New versatile dual-support pediatric heart pump.

abstract：:Cell exclusion is the phenomenon whereby the hematocrit and viscosity of blood decrease in areas of high stress. While this is well known in naturally occurring Poiseuille flow in the human body, it has never previously been shown in Couette flow, which occurs in implantable devices including blood pumps. The high-she...

journal_title：Artificial organs

authors： Leslie LJ,Marshall LJ,Devitt A,Hilton A,Tansley GD

更新日期：2013-03-01 00:00:00

abstract：:This study compares the effects of polyethylene glycol (PEG) modified bovine hemoglobin on vascular half-life and renal function in rabbits to those of unmodified bovine hemoglobin. Renal function was assessed by the measurement of the glomerular filtration rate, urinalysis, blood chemistries, hemoglobin (Hb) excretio...

journal_title：Artificial organs

authors： Conover CD,Gilbert CW,Shum KL,Shorr RG

更新日期：1997-08-01 00:00:00

abstract：:Porcine endogenous retrovirus (PERV) genomes are present in all pig cells. In this retrospective study, we assessed PERV infectivity in 28 patients treated with an extracorporeal bioartificial liver (HepatAssist system) that includes a membrane device containing porcine hepatocytes. All patients tested negative for PE...

journal_title：Artificial organs

authors： Pitkin Z,Mullon C

更新日期：1999-09-01 00:00:00

abstract：:Improvements in implantable ventricular assist device (VAD) performance will be required to obtain patient outcomes that are comparable with those of heart transplantation. The HeartQuest VAD (WorldHeart, Oakland, CA, U.S.A.) is an advanced device, with full magnetic suspension of the rotor, designed to address specif...

journal_title：Artificial organs

authors： Bearnson GB,Jacobs GB,Kirk J,Khanwilkar PS,Nelson KE,Long JW

更新日期：2006-05-01 00:00:00

abstract：:The maximum ventricular elastance is a reliable index for assessing the cardiac function from changes in its pressure-volume relationship. The advantage of this index is that it can represent the contractility of either unassisted hearts or native hearts assisted with rotary blood pumps. However, there are situations ...

journal_title：Artificial organs

authors： Sugai TK,Tanaka A,Yoshizawa M,Shiraishi Y,Yambe T,Nitta S,Baba A

更新日期：2010-05-01 00:00:00

abstract：:In a typical open-heart surgery, the blood flow through the aortic cannula is a critical element of the cardiopulmonary bypass (CPB) procedure. Especially for the neonatal and pediatric CPB flow conditions, the need for small hydraulic diameter and large blood flow results confined turbulent jet flow regimes that exac...

journal_title：Artificial organs

authors： Rasooli R,Pekkan K

更新日期：2019-10-01 00:00:00

abstract：:We previously demonstrated that tumor necrosis factor-alpha (TNF-alpha) increased following a reduction in systemic blood flow to 60% or less of the original cardiac output using a left ventricular assist device (LVAD). The aim of this study was to investigate the effect of reducing systemic blood flow on tissue oxyge...

journal_title：Artificial organs

authors： Uozaki Y,Dihmis WC,Yamauchi H,Moczar M,Miyama M,Pasteau F,Tixier D,Bambang SL,Loisance DY

更新日期：2001-01-01 00:00:00

abstract：:Planar particle image velocimetry was used to explore the flow behavior of the newly designed 12-cc Penn State pneumatic pediatric assist pump. Wall shear maps complemented the velocity data. Bjork-Shiley Monostrut 17-mm mechanical heart valves were used in the inlet and outlet ports. In comparison with larger Penn St...

journal_title：Artificial organs

authors： Manning KB,Wivholm BD,Yang N,Fontaine AA,Deutsch S

更新日期：2008-06-01 00:00:00

abstract：:Individualized short hemodialysis treatment schedules, approximately three 3-h treatments per week, were introduced in a nephrology unit in 1976. In May 1985, 259 patients had been treated, which corresponds to approximately 60 new patients per million inhabitants per year. Ages at start of therapy ranged between 17 a...

journal_title：Artificial organs

authors： Wauters JP,Bercini-Pansiot S,Gilliard N,Stauffer JC

更新日期：1986-06-01 00:00:00

abstract：:Changes in plasma sodium (Na) concentration during hemodialysis were predicted by changes in Na concentration of the dialysate at equilibrium with the plasma, according to the formula C't = CD - (CD - C'0) [(V0 - QFt)/V0]A/QF, where C'0 and C't are the Na concentration of the dialysate at equilibrium with the plasma a...

journal_title：Artificial organs

authors： Man NK,Petitclerc T,Tien NQ,Jehenne G,Funck-Brentano JL

更新日期：1985-05-01 00:00:00

abstract：:A centrifugal blood pump with a double pivot impeller and an eccentric inlet port is being developed as an implantable artificial heart by the Baylor College of Medicine and Miwatec Co. Ltd. Flow visualization measurements were conducted to compare the flow around the pivot for two impeller operational modes: the top ...

journal_title：Artificial organs

authors： Yamane T,Kodama T,Nishida M,Maruyama O,Yamamoto Y,Shinohara T,Motomura T,Nosé Y

更新日期：2006-01-01 00:00:00

abstract：:Tissue engineering can improve the former limitations of artificial organs. This article reports the long-term clinical results of grafts constructed with fragmented autologous adipose tissue. We did a retrospective analysis of a series of 53 patients with lower leg ischemia that received 69 fragmented adipose tissue ...

journal_title：Artificial organs

authors： Karube N,Soma T,Noishiki Y,Yamazaki I,Kosuge T,Ichikawa Y,Takanashi Y

更新日期：2001-03-01 00:00:00

abstract：:Over a 4 year period, five of 98 patients at our dialysis unit developed signs and symptoms consistent with first-use syndrome (FUS). Marked improvement was noted after subjecting new dialyzers to automated processing using either formaldehyde or peracetic acid. No episodes of FUS occurred in patients being treated wi...

journal_title：Artificial organs

authors： Vanholder R,Ringoir S

更新日期：1987-04-01 00:00:00

abstract：:Since the introduction of high-performance prosthetic heart valves, particularly bileaflet valves and monoleaflet valves with larger opening angles, we have observed in vivo complex leaflet motion which has not been experimentally confirmed yet. We developed a computer-controlled hydraulic mock circulator to study the...

journal_title：Artificial organs

authors： Ohta Y,Okamoto K,Sonderegger M,Dohi T,Matsumoto H,Horiuchi T

更新日期：1997-04-01 00:00:00

abstract：:In an attempt to find an adequate end-point rewarming temperature after hypothermic cardiopulmonary bypass (CPB), 50 pediatric patients who underwent cardiac surgery were randomly assigned for the end-point rectal rewarming temperature at either 35.5 (Group 1) or 37.0 degrees C (Group 2). The patients' rectal temperat...

journal_title：Artificial organs

authors： Kim WG,Yang JH

更新日期：2005-11-01 00:00:00

abstract：:In this study, we have developed an implantable electronics unit (IEU) for driving an undulation pump-left ventricular assist device (UP-LVAD). The IEU consists of a pump driver, three series-connected lithium ion batteries (1800 mAh), a charger, and a transcutaneous information transmission system. These electronic s...

journal_title：Artificial organs

authors： Okamoto E,Makino T,Inoue Y,Tanaka S,Yasuda T,Nakamura M,Saito I,Abe Y,Chinzei T,Isoyama T,Mochiizuki S,Imachi K,Mitamura Y

更新日期：2006-05-01 00:00:00

abstract：:The ventricular assist device inflow cannulation site is the primary interface between the device and the patient. Connecting these cannulae to either atria or ventricles induces major changes in flow dynamics; however, there are little data available on precise quantification of these changes. The objective of this i...

journal_title：Artificial organs

authors： Timms D,Gregory S,Hsu PL,Thomson B,Pearcy M,McNeil K,Fraser J,Steinseifer U

更新日期：2010-09-01 00:00:00

abstract：:This study was planned to investigate whether part of the energy produced by cardiac contraction to propel blood toward the systemic circulation can be used to increase the coronary flow in systole. Ten devices (I-X) designed to divert laterally part of a flow column (without substantially increasing resistance to flo...

journal_title：Artificial organs

authors： Moulopoulos S,Stamatelopoulos S,Boufas D,Yannopoulos C,Marousis G,Kouvaras G

更新日期：1979-11-01 00:00:00

abstract：:Five hundred and eighty homograft valves have been inserted into the aortic position as isolated valve replacements, and followed up for 7--14 years. After ten years 90% of frozen homografts, 80% of autografts and 70% of freeze-dried homografts were free of valve-related death. There was only one embolism reported giv...

journal_title：Artificial organs

authors： Bodnar E,Wain WH,Martelli V,Ross DN

更新日期：1980-02-01 00:00:00

abstract：:Right ventricular (RV) function immediately after left ventricular assist device (LVAD) implantation is a crucial prognostic factor. RV failure is linked to increased mortality and worse outcome. A phosphodiesterase 5 inhibitor, sildenafil, was shown to decrease pulmonary vascular resistance and pulmonary artery press...

journal_title：Artificial organs

authors： Hamdan R,Mansour H,Nassar P,Saab M

更新日期：2014-11-01 00:00:00

abstract：:In clinical settings, no method has been established to examine the fatigue of a latissimus dorsi muscle (LDM) preconditioned for cardiomyoplasty. We examined the feasibility of measuring muscle stiffness (tactile stiffness) to evaluate muscle fatigue in situ using our tactile sensor. We stimulated canine LDM with bur...

journal_title：Artificial organs

authors： Inaba H,Miyaji K,Kaneko Y,Ohtsuka T,Ezure M,Tambara K,Takamoto S,Omata S

更新日期：2000-10-01 00:00:00

abstract：:Although the debate still continues over the effectiveness of pulsatile versus nonpulsatile perfusion, it has been clearly proven that there are several significant physiological benefits of pulsatile perfusion during cardiopulmonary bypass (CPB) compared to nonpulsatile perfusion. However, the components of the extra...

journal_title：Artificial organs

authors： Undar A,Lodge AJ,Daggett CW,Runge TM,Ungerleider RM,Calhoon JH

更新日期：1998-08-01 00:00:00

abstract：:When cavitation occurs near a material surface of a mechanical heart valve (MHV), pits on the surface of the MHV and hemolysis are caused. Therefore, it is very important to investigate the possibility of the occurrence of cavitation in an MHV. To study the possibility of cavitation occurrence in a 25 mm Björk-Shiley ...

journal_title：Artificial organs

authors： Lee H,Tsukiya T,Homma A,Taenaka Y,Tatsumi E,Takano H

更新日期：2003-08-01 00:00:00

abstract：:The injurious effects of reactive oxygen species on venous tissues and the potential protective role played by green tea polyphenol (GTPP) on human saphenous veins were investigated. Oxidative stress was induced exogenously in the vein segments, either by adding 0.8 or 1.6 M of H2O2, or by using 80 or 160 U/L of xanth...

journal_title：Artificial organs

authors： Han DW,Suh H,Park YH,Cho BK,Hyon SH,Park JC

更新日期：2003-12-01 00:00:00

abstract：:Current hemodialysis treatment is insufficient because of intermittent treatment and loss of tubular function. In order to overcome the loss of tubular function, a bioartificial kidney has been developed consisting of continuous hemofiltration (CHF) with 10 L/day of filtrate and a bioartificial tubule device using pro...

journal_title：Artificial organs

authors： Saito A

更新日期：2004-01-01 00:00:00

abstract：:Changing financial incentives have strongly influenced dosing patterns of recombinant human erythropoietin (rHuEPO) since its introduction in 1989. Although guidelines for prescribing rHuEPO exist, the extent to which they are adhered to is unknown. Using a retrospective cohort observational study design, the factors ...

journal_title：Artificial organs

authors： Thamer M,Richard CM,Klinkmann J,Ivanovich P,Lang G,Cotter DJ

更新日期：2000-02-01 00:00:00

abstract：:In this study, we investigated the differences between pulsatile cardiopulmonary bypass (CPB) procedure and nonpulsatile CPB procedure in terms of their effects on hemolysis and deformability of red blood cells (RBCs) under various shear stress conditions. In order to research the effects on hemolysis and deformabilit...

journal_title：Artificial organs

authors： Kang YJ,Kim MG,Son KH,Lim CH,Son HS,Yoon SY,Kwon HS,Yang S

更新日期：2010-04-01 00:00:00

abstract：:The trend in neural prostheses using selective nerve stimulation for electrical stimulation therapies is headed toward single-part systems having a large number of working electrodes (WEs), each of which selectively stimulate neural tissue or record neural response (NR). The present article reviews the electrochemical...

journal_title：Artificial organs

authors： Pečlin P,Mehle A,Karpe B,Rozman J

更新日期：2015-10-01 00:00:00

abstract：:Extracorporeal human lymphatic organs are expected to be excellent tools in the study of human molecular and cellular bases of the immunologic balance and tissue harmony. A rational approach and process to design a device and a procedure to recreate the human lymph node environment in vitro is described with emphasis ...

journal_title：Artificial organs

authors： Giese C,Demmler CD,Ammer R,Hartmann S,Lubitz A,Miller L,Müller R,Marx U

更新日期：2006-10-01 00:00:00

abstract：:To elucidate the precise mechanism of carpal tunnel syndrome (CTS), serum hyaluronic acid (HA), interleukin-1 beta (IL-1 beta), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-alpha) were measured in 71 chronic hemodialysis patients with or without CTS and/or shoulder pain. Patients were divided into two gr...

journal_title：Artificial organs

authors： Takasu S,Takatsu S,Kunitomo K,Kokumai Y

更新日期：1994-06-01 00:00:00