Abstract:
:This study was planned to investigate whether part of the energy produced by cardiac contraction to propel blood toward the systemic circulation can be used to increase the coronary flow in systole. Ten devices (I-X) designed to divert laterally part of a flow column (without substantially increasing resistance to flow) were tested in a mock circulation and in nine anesthetized dogs. An increase of 11.69 +/- 1.97% (mean +/- SEM, P less than 0.005) in "coronary flow" and of 8.98 +/- 0.56% (mean +/- SEM, P less than 0.001) in coronary sinus flow were obtained with device I mounted on a stylet and placed above the "aortic valve" in the mock circulation and the dogs, respectively, without increasing the flow resistance. The results in;dicate the possibility of diverting part of the aortic flow toward the coronary arteries without increasing mean aortic pressure.
journal_name
Artif Organsjournal_title
Artificial organsauthors
Moulopoulos S,Stamatelopoulos S,Boufas D,Yannopoulos C,Marousis G,Kouvaras Gdoi
10.1111/j.1525-1594.1979.tb01080.xsubject
Has Abstractpub_date
1979-11-01 00:00:00pages
370-4issue
4eissn
0160-564Xissn
1525-1594journal_volume
3pub_type
杂志文章abstract::To save priming time and perform more rapid initiation of emergency cardiopulmonary bypass for acute cardiopulmonary failure, an extracorporeal circuit with a hollow-fiber oxygenator (EL-2000 for pediatric use; Kurary Co. Ltd., Osaka, Japan) was preprimed, and the gas-exchange function was evaluated after 1 year of st...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1992.tb00331.x
更新日期:1992-10-01 00:00:00
abstract::Thousands of ventricular assist devices (VADs) currently provide circulatory support to patients worldwide, and dozens of heart pump designs for adults and pediatric patients are under various stages of development in preparation for translation to clinical use. The successful bench-to-bedside development of a VAD inv...
journal_title:Artificial organs
pub_type: 杂志文章,评审
doi:10.1111/aor.12600
更新日期:2016-06-01 00:00:00
abstract::The thrombogenicity of membrane oxygenators as well as clotting parameters profiles, using standard human clotting tests, was analyzed in calves and pigs during 6 h perfusion. Three calves and 3 pigs were connected to extracorporeal circulation with standard heparinization. Blood samples were taken for coagulation var...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.2001.025007579.x
更新日期:2001-07-01 00:00:00
abstract::With the goal of investigating artificial proprioception elicited by electrical stimulation, we have developed a tactile phi phenomenon-based stimulator. This two-channel microprocessed pulse amplitude modulation system generates two different envelope waveforms (triangular and elliptical) and allows programming and v...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1995.tb02318.x
更新日期:1995-03-01 00:00:00
abstract::Experiments have been successfully performed culminating in functional, vascularized, three-dimensional cardiac muscle tissue. Past experience in tissue engineering has led us to the understanding that cell seeding density plays a critical role in the formation and function of both in vitro and in vivo engineered tiss...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2008.00591.x
更新日期:2008-09-01 00:00:00
abstract::Thrombosis and thromboembolism are the life-threatening clinical complications for patients supported or treated with prosthetic cardiovascular devices. The high mechanical shear stress within these devices is believed to be the major contributing factor to cause platelet activation (PA) and function alteration, leadi...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.12438
更新日期:2015-07-01 00:00:00
abstract::Modular hip prostheses are commonly used today. Dedicated surgical auxiliary instrumentation is indispensable. A correct coupling between the prosthesis and the instrument is necessary to avoid damage. Based on a specific commercial design (AnCAFit, Wright Cremascoli Ortho, Toulon, France), the aim of this work was to...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2006.00261.x
更新日期:2006-07-01 00:00:00
abstract::Oxidative stress is crucial in red blood cell (RBC) damage induced by activated neutrophils in in vitro experiments. The aim of the study was to evaluate whether the bioincompatibility phenomena occurring during hemodialysis (HD) (where neutrophil activation with increased free radical production is well documented) m...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.2000.06432.x
更新日期:2000-01-01 00:00:00
abstract::Using urea and inulin as markers, we have developed a simple method to calculate intracellular and extracellular fluid volume in patients before and after hemofiltration therapy. During conventional hemofiltration using substitution fluid with a Na+ concentration of 140 mEq/L, a decrease in extracellular fluid volume ...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1982.tb04054.x
更新日期:1982-02-01 00:00:00
abstract::Thirteen percent of 99 patients undergoing maintenance hemodialysis showed an increased predialysis peripheral blood eosinophil count (mean value of 828 cells/mm3, range 410-2,710). Patients with eosinophilia were predominantly male and evidenced more frequent elevation of total plasma IgE levels. Otherwise, no differ...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1987.tb02635.x
更新日期:1987-04-01 00:00:00
abstract::We were encouraged to investigate the reasons for large amounts of foam observed in bloodlines during hemodialysis (HD). Foam was visible in the venous air trap within the Artis Gambro dialysis device. Estimates of the extent of foam were graded (0-no foam, 10-extensive foam) by two persons that were blind to the type...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.13070
更新日期:2018-05-01 00:00:00
abstract::A review and analysis of 5,001 neonatal venoarterial (VA) extracorporeal membrane oxygenation (ECMO) cases showed that bacterial and fungal infection occurred in 147 (2.9%) and 26 (0.6%) patients, respectively, with an overall incidence of 3.5%. Bivariate analysis was used to compare infected infants with controls, ba...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1996.tb04428.x
更新日期:1996-03-01 00:00:00
abstract::Spiral/helical forms of blood flow have been observed in large arteries of the cardiovascular system, but their benefits remain underappreciated. Spiral flow has been postulated to improve near-wall washout, promoting anti-atherothrombotic conditions. This research aims to study the washout characteristics of spiral f...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.13520
更新日期:2019-12-01 00:00:00
abstract::One hundred eighty-eight Mitroflow pericardial valves, implanted on 166 patients from March 1983 to December 1986, have been followed for a total of 4316 patients x months. Mortality rate in the first three postoperative months is approximately 10% related to noncardiac complications. One hundred forty-nine patients a...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1988.tb02781.x
更新日期:1988-08-01 00:00:00
abstract::Eight patients were studied during four sessions of acetate-free biofiltration (AFBF). AFBF is a new dialysis technique with no base replacement agents in the dialysate and with the addition in postdilution mode of bicarbonate (HCO3) solution directly into the extracorporeal blood circuit. In this study the effects on...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1989.tb01561.x
更新日期:1989-10-01 00:00:00
abstract::The heparin-conjugated fibrin (HCF) system has been developed to deliver bone morphogenetic proteins (BMPs) for a long-term period and thus enhance bone regeneration. In the present study, we tested the effectiveness of the delivery system for spinal fusion with a very low dose of BMP-2. A total of 15 rabbits underwen...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2012.01578.x
更新日期:2013-05-01 00:00:00
abstract::To date, single-needle (SN) hemodialysis (HD) requires a dialysis machine equipped with two blood pumps-one controlling arterial blood flow (Qb) and one controlling venous Qb. B. Braun has developed an innovative single-pump SN HD system. Therefore, usability is improved by reducing complexity. The aim of this study w...
journal_title:Artificial organs
pub_type: 杂志文章,随机对照试验
doi:10.1111/aor.13149
更新日期:2018-08-01 00:00:00
abstract::We developed a new left ventricular (LV) assist catheter (transaortic valve from LV to femoral artery) that is implemented percutaneously and exerted as a synchronous pulsatile partial LV flow support with conventional intraaortic balloon pump (IABP) driving system and centrifugal pump system. We investigated whether ...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1992.tb00311.x
更新日期:1992-06-01 00:00:00
abstract::A compact three-dimensional (3D) module is needed for hepatocyte culture in order to develop an effective hybrid artificial liver system that can retain hepatocellular structure and differentiated functions. We treated the 3D module with collagen gel to entrap rat hepatocytes. This method yielded a high hepatocellular...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1995.tb02310.x
更新日期:1995-02-01 00:00:00
abstract::To elucidate the precise mechanism of carpal tunnel syndrome (CTS), serum hyaluronic acid (HA), interleukin-1 beta (IL-1 beta), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-alpha) were measured in 71 chronic hemodialysis patients with or without CTS and/or shoulder pain. Patients were divided into two gr...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1994.tb02227.x
更新日期:1994-06-01 00:00:00
abstract:BACKGROUND:DALI (direct adsorption of lipids) is the first LDL-apheresis technique able to adsorb low-density lipoprotein (LDL) and lipoproteina) directly from whole blood. In the standard procedure, acid citrate dextrose (ACD-A) is used as anticoagulation and the adsorber is rinsed with a specially manufactured primin...
journal_title:Artificial organs
pub_type: 临床试验,杂志文章
doi:10.1046/j.1525-1594.2003.07104.x
更新日期:2003-06-01 00:00:00
abstract::Many patients who receive a prosthetic heart valve also have or acquire cardiac arrhythmias. However, most in vitro studies of prosthetic valves examine them under normal rhythms. In this study, a monoleaflet prosthetic heart valve was tested in vitro under conditions that simulated normal sinus rhythm, first degree a...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2005.29101.x
更新日期:2005-08-01 00:00:00
abstract::The flow of blood as a viscous, Newtonian, incompressible liquid in an expanding spherical cavity with a ball-type inlet valve was examined. This type of flow can serve as a model of the phase of ventricular diastole in a sac-type artificial heart. The critical values of Reynolds numbers at which flow interruption beh...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1983.tb04170.x
更新日期:1983-02-01 00:00:00
abstract::As known from patients with pulsatile ventricular assist devices (VADs), early mobilization, physical exercise, and return to normal life are essential for optimal recovery. Recently, implantable rotary pumps became available for extended left ventricular support as bridges to transplantation. Modified procedures are ...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.2001.025005331.x
更新日期:2001-05-01 00:00:00
abstract::The aim of this study was to verify if dialysis solution volumes used in patients on continuous ambulatory peritoneal dialysis (CAPD) interfere with pulmonary function and if the pulmonary volumes interfere with the lymphatic absorption of the peritoneal cavity. We submitted 10 CAPD patients with a mean age of 48 +/- ...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.2001.06904.x
更新日期:2001-11-01 00:00:00
abstract::To assess the influence of hydration state on plasma volume (PV) changes during ultrafiltration, 11 clinically normhydrated patients on maintenance hemodialysis were studied intraindividually during 2 hydration states differing by 2-15% of lean body mass (LBM). Plasma volume was measured continually during a 15-min ul...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1995.tb02352.x
更新日期:1995-05-01 00:00:00
abstract::Rotary blood pumps are emerging as a viable technology for total artificial hearts, and the development of physiological control algorithms is accelerated with new evaluation environments. In this article, we present a novel hybrid mock circulation loop (HMCL) designed specifically for evaluation of rotary total artif...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.12380
更新日期:2014-09-01 00:00:00
abstract::The Fas molecule, also designated APO-1/CD95, belongs to the tumor necrosis factor (TNF) receptor family. It is a widely expressed membrane-anchored protein that induces apoptosis by Fas/Fas ligand (Fas-L) mediation. It was reported that Fas-mediated apoptosis plays an important role in regulation of the immune system...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.2000.06591.x
更新日期:2000-08-01 00:00:00
abstract::In total, 30 patients suffering from familial hypercholesterolemia, resistant to diet and lipid-lowering drugs, were treated for up to 6 years (3.6 + or - 1.6; range, 0.2-6.8 years) with low-density lipoprotein (LDL) apheresis. Three different systems were used; the dextran sulfate adsorption system (Kaneka) for 27 of...
journal_title:Artificial organs
pub_type: 临床试验,杂志文章
doi:10.1111/j.1525-1594.1996.tb04455.x
更新日期:1996-04-01 00:00:00
abstract::Porcine endogenous retrovirus (PERV) genomes are present in all pig cells. In this retrospective study, we assessed PERV infectivity in 28 patients treated with an extracorporeal bioartificial liver (HepatAssist system) that includes a membrane device containing porcine hepatocytes. All patients tested negative for PE...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.1999.06444.x
更新日期:1999-09-01 00:00:00