Controlled delivery of low-dose bone morphogenetic protein-2 using heparin-conjugated fibrin in the posterolateral lumbar fusion of rabbits.

abstract：:Cardiopulmonary bypass (CPB), an integral part of valve surgery, is known to cause hemodilution, which can lead to a need for blood transfusion as well as a systemic inflammatory reaction. Our aim was to evaluate a reduced priming (RP) system for CPB with regard to clinical outcomes in patients undergoing valve surger...

journal_title：Artificial organs

authors： Sato K,Namura O,Sogawa M,Shimada K,Tosaka Y,Hayashi J

更新日期：2006-08-01 00:00:00

abstract：:The compliance problem represents a major obstacle in the development of implantable blood pumps. The motor-driven pumps are enclosed in an airtight casing with gas in the motor space. The trapped gas in the motor space either increases the load on the motor during systole or impedes blood sac filling. Potential solut...

journal_title：Artificial organs

authors： Lee S,Rosenberg G,Donachy JH,Wisman CB,Pierce WS

更新日期：1984-02-01 00:00:00

abstract：:Hypertension is an important primary etiology of end-stage renal disease as well as a major factor responsible for progression of renal disease due to other causes. Multiple genetic and environmental factors are responsible for the variable prevalence of hypertension in various parts of the world. Although the frequen...

journal_title：Artificial organs

authors： El-Khashab O

更新日期：2002-09-01 00:00:00

abstract：:Hemodynamic control of left ventricular assist devices (LVADs) is generally a complicated problem due to diverse operating environments and the variability of the patients: both the changes in the circulatory and metabolic parameters as well as disturbances that require adjustment to the operating point. This challeng...

journal_title：Artificial organs

authors： Choi S,Boston JR,Antaki JF

更新日期：2007-02-01 00:00:00

abstract：:Contamination of a ventriculoatrial shunt (VAS) with skin organisms that are usually nonpathogenic may be followed by an immunologically mediated renal injury. The bacteria characteristically involved are coagulase-negative Staphylococci (e.g., Staphylococcus epidermidis), which strongly adhere to the plastic surface ...

journal_title：Artificial organs

authors： Samtleben W,Bauriedel G,Bosch T,Goetz C,Klare B,Gurland HJ

更新日期：1993-08-01 00:00:00

abstract：:Bone marrow mesenchymal stem cells (MSCs) have demonstrated their pluripotency to differentiate into different cell lineages and may be an alternative cell source for vascular tissue engineering. The objective of this study is to create small diameter vessels by seeding and culture of genetically modified MSCs onto a ...

journal_title：Artificial organs

authors： Zhang J,Qi H,Wang H,Hu P,Ou L,Guo S,Li J,Che Y,Yu Y,Kong D

更新日期：2006-12-01 00:00:00

abstract：:The implementation of simultaneous mechanical cavopulmonary assistance having blood pumps located in both of the vena cavae is investigated as an approach to treating patients with an ailing Fontan physiology. Identical intravascular blood pumps are employed to model the hemodynamic support of a patient-specific Fonta...

journal_title：Artificial organs

authors： Throckmorton AL,Lopez-Isaza S,Moskowitz W

更新日期：2013-06-01 00:00:00

abstract：:The trend in neural prostheses using selective nerve stimulation for electrical stimulation therapies is headed toward single-part systems having a large number of working electrodes (WEs), each of which selectively stimulate neural tissue or record neural response (NR). The present article reviews the electrochemical...

journal_title：Artificial organs

authors： Pečlin P,Mehle A,Karpe B,Rozman J

更新日期：2015-10-01 00:00:00

abstract：:Atherosclerosis is accelerated in dialysis patients, but less is known about asymptomatic atherosclerosis and major risk factors in patients with different stages of chronic kidney disease (CKD). We compared intima media thickness (IMT) and plaque occurrence in the carotid arteries in 104 nondiabetic patients (stages ...

journal_title：Artificial organs

authors： Ekart R,Hojs R,Bevc S,Balon BP

更新日期：2008-03-01 00:00:00

abstract：:Short-term diabetes was induced in male Wistar rats with streptozotocin injection. The effects of diabetes on latissimus dorsi (LD) muscle contractile and biochemical properties and acute cardiomyoplasty (CDM) were assessed and compared with data from 16 control rats. Isometric force, contractile properties, and fatig...

journal_title：Artificial organs

authors： De Angelis K,Senna S,Irigoyen MC,Cestari IA

更新日期：2004-04-01 00:00:00

abstract：:Hypoalbuminemia, a strong predictor of morbidity and mortality in hemodialysis patients, can be a consequence of a combination of malnutrition and inflammatory reactions. The purpose of this study was to analyze serum albumin as a marker of nutritional status in maintenance hemodialysis patients with no signs of infla...

journal_title：Artificial organs

authors： Santos NS,Draibe SA,Kamimura MA,Canziani ME,Cendoroglo M,Júnior AG,Cuppari L

更新日期：2003-08-01 00:00:00

abstract：:A comparative study of the thrombogenicity of several microporous membranes was performed using an ex vivo system simulating the conditions in an artificial lung. A study of platelet adhesion and adsorbed protein layer indicated that the membranes separated into three groups. Copolyurethane membranes adsorbed very few...

journal_title：Artificial organs

authors： Knight PM,Lyman DJ

更新日期：1985-02-01 00:00:00

abstract：:The feasibility of extracorporeal adsorption of 1.5-3 L plasma on protein A-Sepharose was investigated in six patients with advanced cancer. Anticoagulation with heparin was associated with respiratory distress syndrome in two patients, most likely caused by complement activation as indicated by a transient leukopenia...

journal_title：Artificial organs

authors： Wallmark A,Grubb A,Freiburghaus C,Flodgren P,Husberg B,Lindholm T,Lindström C,Thysell H,Sjögren HO

更新日期：1984-02-01 00:00:00

abstract：:For the development of a totally implantable ventricular assist system (VAS), we have been developing the vibrating flow pump (VFP), which can generate oscillated blood flow with a relative high frequency (10-50 Hz) for a totally implantable system. In this study, the effects of left ventricular assistance with this u...

journal_title：Artificial organs

authors： Nitta S,Yambe T,Kobayashi S,Hashimoto H,Yoshizawa M,Mastuki H,Tabayashi K,Takeda H

更新日期：1999-01-01 00:00:00

abstract：:The developments in apheresis techniques and their clinical applications world-wide are technologically driven. In the past, apheresis survey statistics have high-lighted both the differences by region in clinical practice and in the types of technologies utilized. Such differences have provided a basis for the scient...

journal_title：Artificial organs

authors： Malchesky PS,Bambauer R,Horiuchi T,Kaplan A,Sakurada Y,Samuelsson G

更新日期：1995-04-01 00:00:00

abstract：:Using urea and inulin as markers, we have developed a simple method to calculate intracellular and extracellular fluid volume in patients before and after hemofiltration therapy. During conventional hemofiltration using substitution fluid with a Na+ concentration of 140 mEq/L, a decrease in extracellular fluid volume ...

journal_title：Artificial organs

authors： Kimura G,Satani M,Kojima S,Kuroda K,Itoh K,Ikeda M

更新日期：1982-02-01 00:00:00

abstract：:This paper presents an overview of the U.S. Food and Drug Administration's regulatory requirements for introducing medical device and diagnostic products into commercial distribution in the United States. For any specific product, the requirements vary depending upon the product's associated risks, classification, and...

journal_title：Artificial organs

authors： Morton WA

更新日期：1982-11-01 00:00:00

abstract：:In chronic cardiomyopathy, mechanical circulatory support (MCS) plays an increasingly important role for children as the shortage of suitable donor hearts increases waiting time on the transplant list. We report our experience with the paracorporal Berlin Heart EXCOR System (Berlin Heart AG, Berlin, Germany) used as a...

journal_title：Artificial organs

authors： Schweiger M,Schrempf J,Sereinigg M,Prenner G,Tscheliessnigg KH,Wasler A,Krumnikel J,Gamillschegg A,Knez I

更新日期：2013-08-01 00:00:00

abstract：:Veno-arterial extracorporeal membrane oxygenation (ECMO) may be implanted using peripheral ECMO (pECMO) or central ECMO (cECMO) cannulation techniques. The aim of this study was to compare the outcome between these two cannulation techniques. A retrospective study was performed at Düsseldorf University Hospital from O...

journal_title：Artificial organs

authors： Saeed D,Stosik H,Islamovic M,Albert A,Kamiya H,Maxhera B,Lichtenberg A

更新日期：2014-07-01 00:00:00

abstract：:Cyclosporine (CyA) has an immunosuppressive effect that might suggest a therapeutic role in idiopathic glomerular conditions. We focused on the optimization of CyA treatment control in patients with idiopathic nephrotic syndrome by using trough-level CyA measurements (C0) and the 2-h postdose levels (C2). Twenty-two p...

journal_title：Artificial organs

authors： Griveas I,Visvardis G,Papadopoulou D,Nakopolou L,Karanikas E,Gogos K,Stavianoudakis G

更新日期：2010-03-01 00:00:00

abstract：:Extracorporeal membrane oxygenation (ECMO) is gaining importance in the perioperative management of lung transplant patients. To date, the ideal substance for anticoagulation of ECMO patients is still a matter of debate. In this study, we describe our experience with the use of low molecular weight heparin (LMWH) in c...

journal_title：Artificial organs

authors： Gratz J,Pausch A,Schaden E,Baierl A,Jaksch P,Erhart F,Hoetzenecker K,Wiegele M

更新日期：2020-06-01 00:00:00

abstract：:Over the last 5 years, 12 patients received ventricular assist devices (VADs) while in postcardiotomy cardiogenic shock. There were 7 male and 5 female patients ranging in age from 22 to 73 years (average age, 54). Eight patients underwent surgery for valve replacements, 3 for coronary artery bypass graftings, and 1 f...

journal_title：Artificial organs

authors： Murakami T,Nakayama H,Irie H,Kino K,Hisamochi K,Koomoto T,Takagaki M,Sugawara E,Senoo Y,Teramoto S

更新日期：1993-07-01 00:00:00

abstract：:Modeling different treatment options before a procedure is performed is a promising approach for surgical decision making and patient care in heart valve disease. This study investigated the hemodynamic impact of different prostheses through patient-specific MRI-based CFD simulations. Ten time-resolved MRI data sets w...

journal_title：Artificial organs

authors： Hellmeier F,Nordmeyer S,Yevtushenko P,Bruening J,Berger F,Kuehne T,Goubergrits L,Kelm M

更新日期：2018-01-01 00:00:00

abstract：:The aim of this study was to evaluate the efficiency of hemoperfusion (HP) through coated resin adsorbent Synachrom E-5 in animal intoxications with organophosphate inhibitors of cholinesterases type of nerve agents. Five anesthetized dogs were intoxicated with 2 to 6 LD50 of VX substance and another 4 with 2 to 3 LD5...

journal_title：Artificial organs

authors： Monhart V,Fusek J,Brndiar M,Tlustakova M

更新日期：1994-10-01 00:00:00

abstract：:Spiral/helical forms of blood flow have been observed in large arteries of the cardiovascular system, but their benefits remain underappreciated. Spiral flow has been postulated to improve near-wall washout, promoting anti-atherothrombotic conditions. This research aims to study the washout characteristics of spiral f...

journal_title：Artificial organs

authors： Huang Zhang P,Tkatch C,Newman R,Grimme W,Vainchtein D,Kresh JY

更新日期：2019-12-01 00:00:00

abstract：:We aimed to evaluate the timing of preoperative intra-aortic balloon pump (IABP) placement and outcomes in patients undergoing off-pump coronary artery bypass grafting (OPCAB). Patients with prophylactic IABP placement before OPCAB presenting between January 1, 2010 and December 31, 2013 were included. Patients were c...

journal_title：Artificial organs

authors： Liu F,Yang F,Du Z,Miao N,Zhao Y,Xu B,Hou X

更新日期：2018-03-01 00:00:00

abstract：:A belt worn controller and lithium-ion battery pack have been developed for use with the initial clinical trials of the Jarvik 2000 heart. Patient interface considerations, safety, and simplicity were major design inputs for the system. The controller was developed using all analog technology to avoid difficulties wit...

journal_title：Artificial organs

authors： Jarvik R,Scott V,Morrow M,Takecuhi E

更新日期：1999-06-01 00:00:00

abstract：:Many patients who receive a prosthetic heart valve also have or acquire cardiac arrhythmias. However, most in vitro studies of prosthetic valves examine them under normal rhythms. In this study, a monoleaflet prosthetic heart valve was tested in vitro under conditions that simulated normal sinus rhythm, first degree a...

journal_title：Artificial organs

authors： Zapanta CM

更新日期：2005-08-01 00:00:00

abstract：:The aim of this study was to verify if dialysis solution volumes used in patients on continuous ambulatory peritoneal dialysis (CAPD) interfere with pulmonary function and if the pulmonary volumes interfere with the lymphatic absorption of the peritoneal cavity. We submitted 10 CAPD patients with a mean age of 48 +/- ...

journal_title：Artificial organs

authors： Marmanillo CG,Pecoits-Filho RF,Romão JE Jr,Kakehashi ET,Sabbaga E,Marcondes M,Abensur H

更新日期：2001-11-01 00:00:00

abstract：:Flow visualization is widely applied to evaluate rotary blood pumps; however, it is very difficult to visualize flow near the vanes of centrifugal blood pumps because the rotational speed of the impeller is usually several thousand rpm. In this study, a tracer method with a high speed video camera that can take more t...

journal_title：Artificial organs

authors： Sakuma I,Tadokoro H,Fukui Y,Dohi T

更新日期：1995-07-01 00:00:00