The mechanics of spiral flow: Enhanced washout and transport.

abstract：:Only a small number of English hospitals provide postcardiotomy venoarterial extracorporeal membrane oxygenation (VA-ECMO) and there are doubts about its efficacy and safety. The aim of this service evaluation was to determine local survival rates and report on patient demographics. This was a retrospective service ev...

journal_title：Artificial organs

authors： Charlesworth M,Garcia M,Head L,Barker JM,Ashworth AD,Barnard JB,Feddy L,Venkateswaran RV

更新日期：2020-07-01 00:00:00

abstract：:Patients with kidney failure can only survive with some form of kidney replacement (transplant or dialysis). Unfortunately, innovations in kidney replacement therapy lag behind many other medical fields. This study compiles expert opinions on candidate technologies for future kidney replacement therapies. A worldwide ...

journal_title：Artificial organs

authors： Pereira Cabral B,Bonventre JV,Wieringa F,Mota FB

更新日期：2020-07-22 00:00:00

abstract：:We tried to verify the hypothesis that increases in pump flow during diastole are matched by decreases in left ventricular (LV) output during systole. A calf (80 kg) was implanted with an implantable centrifugal blood pump (EVAHEART, SunMedical Technology Research Corp., Nagano, Japan) with left ventricle to aorta (LV...

journal_title：Artificial organs

authors： Akimoto T,Litwak KN,Yamazaki K,Litwak P,Kihara SI,Tagusari O,Yamazaki SI,Kameneva MV,Watach MJ,Umezu M,Tomioka J,Kormos RL,Koyanagi H,Griffith BP

更新日期：2001-09-01 00:00:00

abstract：:Cell exclusion is the phenomenon whereby the hematocrit and viscosity of blood decrease in areas of high stress. While this is well known in naturally occurring Poiseuille flow in the human body, it has never previously been shown in Couette flow, which occurs in implantable devices including blood pumps. The high-she...

journal_title：Artificial organs

authors： Leslie LJ,Marshall LJ,Devitt A,Hilton A,Tansley GD

更新日期：2013-03-01 00:00:00

abstract：:Lipid apheresis has developed from a heroic treatment into a routine clinical therapy and currently is the major indication for performing extracorporeal plasma therapy. Whereas it was once reserved for patients with homozygous familial hypercholesterolemia, today it has a place in the secondary prevention of severe c...

journal_title：Artificial organs

authors： Bosch T

更新日期：1996-05-01 00:00:00

abstract：:Artificial oxygen (O2 ) carriers were reported to be protective in ischemia/reperfusion (I/R) in various organs including the heart. In the current study, 20 rats underwent ligation (MI) of the left anterior descending artery, were treated with 10 mL/kg of PEGylated carboxyhemoglobin bovine (SANGUINATE, S+, n = 10) or...

journal_title：Artificial organs

authors： Kawaguchi AT,Salybekov AA,Yamano M,Kitagishi H,Sekine K,Tamaki T

更新日期：2018-12-01 00:00:00

abstract：:The determination of when to stop extracorporeal membrane oxygenation (ECMO) rests upon demonstration of the return of adequate cardiac function to support vital organs and permit subsequent recovery. In general, patients with myocardial stun will recover function within several days. Factors that limit recovery inclu...

journal_title：Artificial organs

authors： Steinhorn DM

更新日期：1999-11-01 00:00:00

abstract：:The use of and demand for functional electrical stimulation (FES) systems and conventional orthoses in the spinal cord lesioned population was assessed. The assessment was conducted by a postal survey of the members of the spinal injury associations in the U.K. Out of all the respondents, only 2% had used an FES syste...

journal_title：Artificial organs

authors： Maxwell DJ,Granat MH,Baardman G,Hermens HJ

更新日期：1999-05-01 00:00:00

abstract：:Molecular biology has been moving swiftly toward clarifying the entire genome of organisms, including human. The human genome efforts that promote this transaction are characterized by the large-scale, high throughput production of data about the structure of the genome of the molecular level and its computer-assisted...

journal_title：Artificial organs

authors： Matsubara K

更新日期：1996-08-01 00:00:00

abstract：:Mechanical circulatory support (MCS) devices continue to be hampered by thrombotic adverse events (AEs), a consequence of device-imparted supraphysiologic shear stresses, leading to shear-mediated platelet activation (SMPA). In advancing MCS devices from design to clinical use, in vitro circulatory loops containing th...

journal_title：Artificial organs

authors： Li M,Walk R,Roka-Moiia Y,Sheriff J,Bluestein D,Barth EJ,Slepian MJ

更新日期：2020-06-01 00:00:00

abstract：:Transplanted allogeneic marrow grafts often fail to engraft in a lethally irradiated host. Resistance to hemopoietic allograft is a complexed phenomenon involving multiple components. To study the involvement of a hemopoietic cytokine, which was known to play a role for stem cell function, we established lines of mice...

journal_title：Artificial organs

authors： Kokai Y,Kimura H,Matsuura A,Fujimoto J

更新日期：1996-08-01 00:00:00

abstract：:To study the microvessels in bulbar conjunctiva, we conducted an experiment in goat with a pneumatically driven left heart bypass pump, which was replaced with an undulation pump-left ventricle assist device for 9 days. Three flow patterns were tested: complete pulsatile, continuous, and percentage of pulsatile. We st...

journal_title：Artificial organs

authors： Dobsák P,Novakova M,Baba A,Vasku J,Isoyama T,Saito I,Abe Y,Chinzei T,Imachi K

更新日期：2006-06-01 00:00:00

abstract：:To assess the efficiency of respiratory gas exchange in vitro through a dialysis membrane mounted inside a flat plate Kiil dialyzer, the model reactions of hydrogen peroxide reduction by a metal ion and of the carbon dioxide precipitation in the form of a carbonate in the dialysate were used. A comparison of the rates...

journal_title：Artificial organs

authors： Zborowski M

更新日期：1983-05-01 00:00:00

abstract：:We made miniature modules filled with artificial oxygenator hollow fibers and conducted a simple experiment to study the effect of different membrane structures on the blood. Three types of modules were made: one filled with polyolefin, one filled with polypropylene, and a blank module. The 3 modules were connected th...

journal_title：Artificial organs

authors： Nishida H,Shibuya M,Endo M,Koyanagi H

更新日期：1996-12-01 00:00:00

abstract：:Continuous hemodiafiltration (CHDF) has been performed for the treatment of severe acute pancreatitis. Phospholipase A2 (PLA2) is one of the important mediators which exacerbate acute pancreatitis, but whether PLA2 can be removed by CHDF is unclear. In this study, the kinetics of group IB and group IIA PLA2 was examin...

journal_title：Artificial organs

authors： Suzuki M,Okahisa T,Sogabe M,Iwaki H,Okita Y,Ohnishi Y,Ito S

更新日期：2007-05-01 00:00:00

abstract：:Individualized short hemodialysis treatment schedules, approximately three 3-h treatments per week, were introduced in a nephrology unit in 1976. In May 1985, 259 patients had been treated, which corresponds to approximately 60 new patients per million inhabitants per year. Ages at start of therapy ranged between 17 a...

journal_title：Artificial organs

authors： Wauters JP,Bercini-Pansiot S,Gilliard N,Stauffer JC

更新日期：1986-06-01 00:00:00

abstract：:The generation of anaphylatoxins, particularly C5a, is important in extracorporeal circulation therapies such as granulocyte/monocyte apheresis, which activates the complement system and elevates C5a levels. However, no side effects of granulocyte/monocyte apheresis using cellulose acetate beads have been reported. To...

journal_title：Artificial organs

authors： Takeda Y,Ohba M,Ueno M,Saniabadi AR,Wakabayashi I

更新日期：2010-12-01 00:00:00

abstract：:Albumin-coated Amberlite XAD-7 has been previously shown to be blood compatible in in vitro hemoperfusion experiments whith human blood. In this study, the preliminary results are reported on single hemoperfusions with albumin-coated XAD-7 resin in four patients with acute liver failure. The mean platelet count was 11...

journal_title：Artificial organs

authors： Hughes R,Ton HY,Langley P,Davies M,Hanid MA,Mellon P,Silk DB,Williams R

更新日期：1979-02-01 00:00:00

abstract：:Oxidative stress is crucial in red blood cell (RBC) damage induced by activated neutrophils in in vitro experiments. The aim of the study was to evaluate whether the bioincompatibility phenomena occurring during hemodialysis (HD) (where neutrophil activation with increased free radical production is well documented) m...

journal_title：Artificial organs

authors： Lucchi L,Bergamini S,Botti B,Rapanà R,Ciuffreda A,Ruggiero P,Ballestri M,Tomasi A,Albertazzi A

更新日期：2000-01-01 00:00:00

abstract：:Jaundice is characterized by an excessive accumulation of bilirubin in the blood and tissues. A novel approach to reduce plasma levels of bilirubin by blocking its enterohepatic circulation was investigated. The treatment consisted of oral administration of immobilized bilirubin oxidase, which could oxidize bilirubin ...

journal_title：Artificial organs

authors： Soltys PJ,Mullon C,Langer R

更新日期：1992-08-01 00:00:00

abstract：:To avoid using sensors with low biocompatibility and low durability in implantable total artificial heart (TAH) systems, the authors previously proposed a new method for estimating instantaneous values of flow rate and pressure head on the basis of voltage, current, and rotational speed in a motor driven centrifugal p...

journal_title：Artificial organs

authors： Tanaka A,Yoshizawa M,Abe K,Takeda H,Yambe T,Nitta S

更新日期：2003-01-01 00:00:00

abstract：:The addition of human serum albumin (HSA) to peritoneal dialysate increases the clearance of bilirubin in rats suffering from obstructive jaundice. The acceptor properties of the fluid can be enhanced by using HSA that does not contain standard stabilizing additives and has been purified by further adsorption on activ...

journal_title：Artificial organs

authors： Sarnatskaya VV,Nikolaev VG,Osipova LA,Ivanov AI,Maslenny VN,Ivanyuk AA,Yushko LA

更新日期：1993-10-01 00:00:00

abstract：:Malnutrition is a common feature seen in chronic dialysis patients, and the survival rate of obese patients receiving such treatment is higher than that of lean patients. Irrespective of obesity or diabetes, dialysis patients commonly have insulin resistance, and the leading cause of death is cardiovascular (CV) disea...

journal_title：Artificial organs

authors： Tanaka S,Yano S,Sheikh AM,Nagai A,Sugimoto T

更新日期：2014-07-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB) is a nonphysiologic environment for an organism. The damage of blood components may also lead to organ dysfunction, some-times recognized as postperfusion syndrome. One possible way to diminish the risk of these complications would be to reduce the thorombogenicity and to improve the bioco...

journal_title：Artificial organs

authors： Horimoto H,Kondo K,Asada K,Sasaki S

更新日期：1996-08-01 00:00:00

abstract：:The aim of this work is the evaluation of four different heat exchangers used for myocardium during cardioplegic system in cardiac surgeries. Four types of shell and tube heat exchangers made of different exchange elements were constructed, as follows: stainless steel tubes, aluminium tubes, polypropylene hollow fiber...

journal_title：Artificial organs

authors： Drummond M,Novello WP,de Arruda AC,Braile DM

更新日期：2003-05-01 00:00:00

abstract：:Changes in plasma sodium (Na) concentration during hemodialysis were predicted by changes in Na concentration of the dialysate at equilibrium with the plasma, according to the formula C't = CD - (CD - C'0) [(V0 - QFt)/V0]A/QF, where C'0 and C't are the Na concentration of the dialysate at equilibrium with the plasma a...

journal_title：Artificial organs

authors： Man NK,Petitclerc T,Tien NQ,Jehenne G,Funck-Brentano JL

更新日期：1985-05-01 00:00:00

abstract：:In this pilot study, we assessed the feasibility of using positron emission tomography (PET) imaging for in vivo measurement of skeletal muscle ventricle (SMV) tissue blood flow. In 4 dogs, with SMVs prepared from their latissimus dorsi muscle, we quantified SMV tissue blood flow by PET and related it to the tissue fl...

journal_title：Artificial organs

authors： Singh TP,Greer K,Muzik O,Hammond RL,Stephenson LW,Di Carli MF

更新日期：2001-04-01 00:00:00

abstract：:We treated 12 patients with rheumatoid arthritis by filtration leukocytapheresis (FLCP) and evaluated its effect on leukocyte enzyme activities. We calculated the number of leukocytes removed and assessed the clinical response. We also evaluated the cellular enzyme activities of elastase and dipeptidylpeptidase IV (DP...

journal_title：Artificial organs

authors： Yamasaki S,Ueki Y,Nakamura H,Yano M,Matsumoto K,Miyake S,Tominaga T,Tominaga M,Eguchi K

更新日期：2002-04-01 00:00:00

abstract：:The effectiveness of the blood substitute neo red cells (NRC) on hemorrhagic shock was evaluated in dogs. Shock was induced by bloodletting, and NRC was infused immediately until the dogs recovered from shock; the process was repeated 3 times (mild shock), or NRC was infused after shock was maintained for 30 min, and ...

journal_title：Artificial organs

authors： Usuba A,Osuka F,Kimura T,Sato R,Fujita Y,Yamashita M,Hoshino C

更新日期：1998-02-01 00:00:00

abstract：:This study probed the changes of keratocytes cultured under simulated microgravity. Keratocytes were isolated from rabbit corneas using collagenase digestion method. Cells were seeded in a 55-mL capacity high-aspect-ratio vessel (HARV) of rotary cell culture system (RCCS) at a density of 1 x 10(4) cells/mL. Dehydrated...

journal_title：Artificial organs

authors： Chen J,Chen R,Gao S

更新日期：2007-09-01 00:00:00