Peritoneal dialysis for the removal of protein-bound markers of hepatic insufficiency.

Abstract:

:The addition of human serum albumin (HSA) to peritoneal dialysate increases the clearance of bilirubin in rats suffering from obstructive jaundice. The acceptor properties of the fluid can be enhanced by using HSA that does not contain standard stabilizing additives and has been purified by further adsorption on activated carbon. Bilirubin-containing dialysate fluid, as well as the ascitic fluid of cirrhotic patients, can be regenerated by a combination of membrane ultrafiltration and carbon adsorption. These observations suggest a potentially useful scheme for continuous, regenerative peritoneal dialysis in the treatment of hepatic insufficiency.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Sarnatskaya VV,Nikolaev VG,Osipova LA,Ivanov AI,Maslenny VN,Ivanyuk AA,Yushko LA

doi

10.1111/j.1525-1594.1993.tb00390.x

subject

Has Abstract

pub_date

1993-10-01 00:00:00

pages

828-36

issue

10

eissn

0160-564X

issn

1525-1594

journal_volume

17

pub_type

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