Abstract:
:To avoid using sensors with low biocompatibility and low durability in implantable total artificial heart (TAH) systems, the authors previously proposed a new method for estimating instantaneous values of flow rate and pressure head on the basis of voltage, current, and rotational speed in a motor driven centrifugal pump. The previous in vitro experiments showed that the proposed estimator could automatically compensate for the effect of the change in blood viscosity on the estimation accuracy by employing two kinds of autoregressive exogenous models. In this study, validity and reliability of this estimation method were ascertained in an acute animal experiment. In the experiment, two centrifugal blood pumps were implanted into an adult goat as a total artificial heart. Results of estimation were compared with true values when blood viscosity was changed by injecting physiological saline. The results indicated that the system could successfully estimate pressure head by compensating the change of viscosity, although the estimation accuracy of the in vivo estimation was not so high as that of the previous in vitro tests.
journal_name
Artif Organsjournal_title
Artificial organsauthors
Tanaka A,Yoshizawa M,Abe K,Takeda H,Yambe T,Nitta Sdoi
10.1046/j.1525-1594.2003.07175.xsubject
Has Abstractpub_date
2003-01-01 00:00:00pages
99-103issue
1eissn
0160-564Xissn
1525-1594pii
7175journal_volume
27pub_type
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journal_title:Artificial organs
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pub_type: 杂志文章
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.12678
更新日期:2016-08-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.2003.07174.x
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journal_title:Artificial organs
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journal_title:Artificial organs
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doi:10.1111/j.1525-1594.2009.00748.x
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journal_title:Artificial organs
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