Abstract:
:Hypertension is an important primary etiology of end-stage renal disease as well as a major factor responsible for progression of renal disease due to other causes. Multiple genetic and environmental factors are responsible for the variable prevalence of hypertension in various parts of the world. Although the frequency of hypertension awareness and control is very modest in the developing world, nephroangiosclerosis seems to be more common in the developed countries. Factors responsible for this discrepancy as well as various strategic measures to control hypertension and its impact on renal disease are discussed.
journal_name
Artif Organsjournal_title
Artificial organsauthors
El-Khashab Odoi
10.1046/j.1525-1594.2002.07067.xsubject
Has Abstractpub_date
2002-09-01 00:00:00pages
765-6issue
9eissn
0160-564Xissn
1525-1594pii
aor7067journal_volume
26pub_type
杂志文章abstract::Ligament reconstruction using a tissue-engineered artificial ligament (TEAL) requires regeneration of the ligament-bone junction such that fixation devices such as screws and end buttons do not have to be used. The objective of this study was to develop a TEAL consisting of elastin-coated polydioxanone (PDS) sutures c...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.13124
更新日期:2018-07-01 00:00:00
abstract::Midsize molecule retention is related with renal-failure-associated mortality. Here, the authors describe a new dialysis modality, pulse push/pull hemodialysis (PPPHD), which increases convective clearance. Blood and dialysate are circulated by a pulsatile pump, but with pulsatile flow patterns that are 180 degrees ou...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2008.00561.x
更新日期:2008-05-01 00:00:00
abstract::A microcapsule suspension, a substitute for animal blood in hemolysis tests, has been developed for evaluation of the absolute hemolytic properties of circulatory artificial organs. The microcapsule suspension was made by dispersing microcapsule slurry into an ethylene glycol sodium chloride solution. The microcapsule...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.1999.06316.x
更新日期:1999-03-01 00:00:00
abstract::An apparatus has been contructed to regulate ultrafiltration accurately during dialysis. The principle of the apparatus is that, per unit of time, exactly the same amount of dialysate is introduced into the dialyzer as is discharged from it. The apparatus consists of two isovolumetric pumps connected in line. The four...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1978.tb03442.x
更新日期:1978-05-01 00:00:00
abstract::The maximum ventricular elastance is a reliable index for assessing the cardiac function from changes in its pressure-volume relationship. The advantage of this index is that it can represent the contractility of either unassisted hearts or native hearts assisted with rotary blood pumps. However, there are situations ...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2009.00876.x
更新日期:2010-05-01 00:00:00
abstract::EXTEND (EXTra-uterine Environment for Neonatal Development) is a novel system for supporting extremely premature infants that replicates in utero conditions by maintaining a sterile fluid environment and providing gas exchange via a pumpless arteriovenous oxygenator circuit connected to the umbilical vessels. Target g...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.13524
更新日期:2019-12-01 00:00:00
abstract::We reviewed the role of the BioMedicus pump in the reduction of neurologic complications following the repair of Type 1 and Type 2 thoracoabdominal aortic aneurysms. Since 1991, we have used several different methods for the repair of thoracoabdominal aortic aneurysms including simple cross-clamping, selective use of ...
journal_title:Artificial organs
pub_type: 临床试验,杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract::Multiple observational studies along with a limited number of randomized clinical trials suggest that intensive hemodialysis (IHD) not only improves outcomes for uremic patients undergoing chronic dialysis but does so with a more favorable cost/benefit ratio compared with conventional hemodialysis. As a result of this...
journal_title:Artificial organs
pub_type: 历史文章,杂志文章,评审
doi:10.1111/aor.12458
更新日期:2015-09-01 00:00:00
abstract::The principle of a patient-specific immunoadsorber (PsIA) is demonstrated. Studies with model systems (HSA/anti-HSA) on immobilization, stability, and leakage form the basis for the presented fast-performance liquid chromatography (FPLC) and batch experiments, which were conducted using two different protein A adsorbe...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.2002.06875.x
更新日期:2002-02-01 00:00:00
abstract::Spiral/helical forms of blood flow have been observed in large arteries of the cardiovascular system, but their benefits remain underappreciated. Spiral flow has been postulated to improve near-wall washout, promoting anti-atherothrombotic conditions. This research aims to study the washout characteristics of spiral f...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.13520
更新日期:2019-12-01 00:00:00
abstract::In this study two aspects of hybrid functional electrical stimulation (FES) orthoses were investigated: joint motion constraints and FES control strategies. First, the effects of joint motion constraints on the gait of normal subjects were investigated using modern motion analysis systems, including electromyogram (EM...
journal_title:Artificial organs
pub_type: 临床试验,杂志文章
doi:10.1111/j.1525-1594.1997.tb04648.x
更新日期:1997-03-01 00:00:00
abstract::The Genius is a convenient single-pass batch hemodialysis system. Dialysate is heated during the preparation phase. Once the container is filled at one of the three available starting temperatures, dialysate cools spontaneously. As dialysate temperature plays an important role in hemodynamic stability, knowledge of th...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2009.00981.x
更新日期:2010-12-01 00:00:00
abstract::Mechanical circulatory support (MCS) devices for pediatric patients continue to lag in development behind those for adults. There is no heart pump with the design innovation to support dysfunctional states of heart failure and the anatomic heterogeneity of cardiac defects in pediatric patients. To address this unmet n...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.13507
更新日期:2019-11-01 00:00:00
abstract::We designed a 24-field array and an on-line control box that selects which and how many of 24 fields will conduct electrical charge during functional electrical stimulation. The array was made using a conductive microfiber textile, silver two-component adhesive, and the conductive ink imprint on the polycarbonate. The...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2005.29075.x
更新日期:2005-06-01 00:00:00
abstract::Although extracorporeal membrane oxygenation (ECMO) improves oxygenation, pulmonary vascular resistance may be increased due to endothelial function impairment. Inhaled nitric oxide (iNO) is increasingly used for treatment of pulmonary hypertension after surgical repair of congenital heart defects, with or without ECM...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.1999.06448.x
更新日期:1999-11-01 00:00:00
abstract::Bicarbonate balance is usually calculated from the Henderson-Hasselbalch equation under the assumption that pK is constant. To evaluate the pK variability and its effects on bicarbonate computed with autoanalyzers in dialysis patients, we studied 44 patients on maintenance hemodialysis. The pH, PCO2, total CO2, and pK...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1987.tb02715.x
更新日期:1987-12-01 00:00:00
abstract::For the development of a totally implantable ventricular assist system (VAS), we have been developing the vibrating flow pump (VFP), which can generate oscillated blood flow with a relative high frequency (10-50 Hz) for a totally implantable system. In this study, the effects of left ventricular assistance with this u...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.1999.06288.x
更新日期:1999-01-01 00:00:00
abstract::The presence in rat serum of three novel immunosuppressive proteins is associated with induction of tolerance after liver grafting. One of these, KX-5 (40 kilodalton molecular weight) is present 40-100 days after grafting of DA liver into PVG, a combination in which liver grafts are not rejected; two others, KX-2 (87 ...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1996.tb00646.x
更新日期:1996-10-01 00:00:00
abstract::Extracorporeal membrane oxygenation (ECMO) is used for severe acute respiratory distress syndrome. However, available ECMO systems are large and not well designed for fast delivery, emergency implantation, and interhospital transfer. Therefore, a new miniaturized oxygenator with integrated rotary blood pump (ILIAS) wa...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.12611
更新日期:2016-07-01 00:00:00
abstract::Centrifugal blood pumps are considered to be generally superior to the traditionally used roller pumps in cardiopulmonary bypass. In our institute a new lightweight centrifugal sealless blood pump with a unique spherical thrust bearing and with a magnetic coupling was developed, the HiFlow. The small design makes the ...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1997.tb03754.x
更新日期:1997-07-01 00:00:00
abstract::The effect of blood hematocrit (HCT) on a noninvasive flow estimation algorithm was examined in a centrifugal implantable rotary blood pump (iRBP) used for ventricular assistance. An average flow estimator, based on three parameters, input electrical power, pump speed, and HCT, was developed. Data were collected in a ...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2007.00339.x
更新日期:2007-01-01 00:00:00
abstract::Aortic wall thinness was one of the most characteristic changes observed in experimental animals under prolonged continuous flow left heart bypass. The goal of this study was to determine the roles of smooth muscle cells in the vascular remodeling process in cases demonstrating aortic wall thinness under prolonged con...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.2003.00022.x
更新日期:2003-10-01 00:00:00
abstract::We tried to verify the hypothesis that increases in pump flow during diastole are matched by decreases in left ventricular (LV) output during systole. A calf (80 kg) was implanted with an implantable centrifugal blood pump (EVAHEART, SunMedical Technology Research Corp., Nagano, Japan) with left ventricle to aorta (LV...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.2001.06864.x
更新日期:2001-09-01 00:00:00
abstract::Low molecular weight heparin (LMH) acts as an anticoagulation agent mainly through its anti-activated coagulation factor X (Xa) activity. Thrombelastography (TEG) is expected to be useful to monitor the dosage of LMH during hemodialysis because reaction time on TEG (TEG-r) is considered to reflect blood thromboplastin...
journal_title:Artificial organs
pub_type: 临床试验,杂志文章
doi:10.1111/j.1525-1594.1990.tb02996.x
更新日期:1990-12-01 00:00:00
abstract::We have studied the cardiac beat synchronization (CBS) control for a rotary blood pump (RBP) and revealed that it can promote pulsatility and reduce cardiac load. Besides, patients with LVAD support sometimes suffer from aortic and mitral regurgitation (AR and MR). A control method for the RBP should be validated in w...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.13795
更新日期:2020-08-19 00:00:00
abstract::Creating an interatrial shunt to achieve left-right flow balance and modification of the blood chambers to improve the basic performance of the device were performed in developing an eccentric roller type total artificial heart (ERTAH). Smaller blood chambers reduce friction loss and increase durability and energy eff...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.2000.06602.x
更新日期:2000-08-01 00:00:00
abstract::Adsorption therapy, which treats the autoimmune disease by the selective removal of pathogenic substances from the blood, is an active subject. In this therapy, bioactive molecules such as antigen, antibodies and protein A are usually used as affinity-ligands. The disadvantages of using these substances as affinity-li...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1990.tb02977.x
更新日期:1990-10-01 00:00:00
abstract::The purpose was to evaluate the cytotoxicity of two novel formulations (alpha and beta) of calcium phosphate cements. Positive control, represented by a commercial hydroxyapatite cement, and negative control were included for comparative purposes. A continuous lineage of fibroblastic cells was used, and the effect of ...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2005.29022.x
更新日期:2005-02-01 00:00:00
abstract::The neutralization of bacterial endotoxins (ET) is still an unsolved problem in therapeutic medicine. The efficacy of anti-endotoxin antibodies or receptor antagonists and other substances interfering with the endotoxin-induced pathomechanisms is dependent on an intact cellular degradation system of the host. However,...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1993.tb00630.x
更新日期:1993-09-01 00:00:00
abstract::Mechanical circulatory support (MCS) devices continue to be hampered by thrombotic adverse events (AEs), a consequence of device-imparted supraphysiologic shear stresses, leading to shear-mediated platelet activation (SMPA). In advancing MCS devices from design to clinical use, in vitro circulatory loops containing th...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.13626
更新日期:2020-06-01 00:00:00