A preliminary study of microcapsule suspension for hemolysis evaluation of artificial organs.

abstract：:Controlled and repeatable in vitro evaluation of cardiovascular devices using a mock circulation loop (MCL) is essential prior to in vivo or clinical trials. MCLs often consist of only a systemic circulation with no autoregulatory responses and limited validation. This study aimed to develop, and validate against huma...

journal_title：Artificial organs

authors： Gregory SD,Pauls JP,Wu EL,Stephens A,Steinseifer U,Tansley G,Fraser JF

更新日期：2020-06-01 00:00:00

abstract：:This study assessed the efficacy of multiarterial bypass in coronary artery bypass grafting (CABG) in dialysis patients. Eighty dialysis patients who underwent CABG were divided into 2 groups. Group A consisted of 38 patients in whom the left internal thoracic artery and additional saphenous vein graft (SVG) had been ...

journal_title：Artificial organs

authors： Nakayama Y,Sakata R,Ura M

更新日期：2001-04-01 00:00:00

abstract：:A computational fluid dynamic model to assess the impact of flow-diverter device on intra-aneurysmal flow in complex aortic aneurysm from the viewpoint of hemodynamics is presented. The aim of this study is to investigate the hemodynamic effects of an endovascular flow-diverter technique using multiple overlapping unc...

journal_title：Artificial organs

authors： Yeow SL,Leo HL

更新日期：2018-02-01 00:00:00

abstract：:Left dominant biventricular failure is a common type of heart failure after cardiac surgery. We developed a biventricular bypass (BVB) system for treatment of postcardiotomy ventricular failure, and we previously reported that the clinical results of the BVB system were superior to those obtained with venoarterial byp...

journal_title：Artificial organs

authors： Kodera K,Kitamura M,Shibuya M,Kurihara H,Koyanagi H

更新日期：1998-09-01 00:00:00

abstract：:Tissue responses to various percutaneous materials with different surface properties and structures were investigated. Dense hydroxyapatite (HA), tricalcium phosphate (TCP), glassy carbon (GC), and 2 types of porous HA were used. Cutaneous and subcutaneous tissues were tightly attached to the surface of the penetratin...

journal_title：Artificial organs

authors： Shin Y,Akao M

更新日期：1997-09-01 00:00:00

abstract：:Mechanical circulatory support (MCS) devices continue to be hampered by thrombotic adverse events (AEs), a consequence of device-imparted supraphysiologic shear stresses, leading to shear-mediated platelet activation (SMPA). In advancing MCS devices from design to clinical use, in vitro circulatory loops containing th...

journal_title：Artificial organs

authors： Li M,Walk R,Roka-Moiia Y,Sheriff J,Bluestein D,Barth EJ,Slepian MJ

更新日期：2020-06-01 00:00:00

abstract：:This study deals with the design of a controller for cycling induced by functional electrical stimulation. The controller will be exploitable in the rehabilitation of hemiparetic patients who need to recover motor symmetry. It uses the pulse width as the control variable in the stimulation of the two legs in order to ...

journal_title：Artificial organs

authors： Ambrosini E,Ferrante S,Schauer T,Ferrigno G,Molteni F,Pedrocchi A

更新日期：2010-08-01 00:00:00

abstract：:Recent studies show that oxytocin has various effects on cellular behaviors. Oxytocin is reported to stimulate cardiomyogenesis of embryonic stem cells and endothelial cell proliferation. Mesenchymal stem cells (MSCs) are widely used for cardiac repair, and we elucidated the effect of oxytocin on umbilical cord derive...

journal_title：Artificial organs

authors： Kim YS,Kwon JS,Hong MH,Kim J,Song CH,Jeong MH,Cho JG,Park JC,Kang JC,Ahn Y

更新日期：2010-06-01 00:00:00

abstract：:The use of extracorporeal membrane oxygenator instead of standard cardiopulmonary bypass during lung transplantation is debatable. Moreover, recently, the concept of prolonged postoperative extracorporeal membrane oxygenator (ECMO) support has been introduced in many transplant centers to prevent primary graft dysfunc...

journal_title：Artificial organs

authors： Dell'Amore A,Campisi A,Congiu S,Mazzarra S,Pastore S,Dolci G,Baiocchi M,Frascaroli G

更新日期：2020-06-01 00:00:00

abstract：:Artificial cells are prepared in the laboratory for medical and biotechnological applications. Encapsulated cells are being studied for the treatment of diabetes, liver failure, and other conditions. More recently, there have been extensive studies into the use of encapsulated genetically engineered cells for gene the...

journal_title：Artificial organs

authors： Chang TM

更新日期：1998-11-01 00:00:00

abstract：:Patients with kidney failure can only survive with some form of kidney replacement (transplant or dialysis). Unfortunately, innovations in kidney replacement therapy lag behind many other medical fields. This study compiles expert opinions on candidate technologies for future kidney replacement therapies. A worldwide ...

journal_title：Artificial organs

authors： Pereira Cabral B,Bonventre JV,Wieringa F,Mota FB

更新日期：2020-07-22 00:00:00

abstract：:The treatment of rheumatoid arthritis remains difficult and often controversial. Plasma exchange has been advocated in some cases. In the present study 71 sessions of double filtration plasmapheresis (DFPP) were performed in 21 patients with rheumatoid arthritis in an average of 3.7 +/- 1.1 sessions per patient within...

journal_title：Artificial organs

authors： Liu JD,Zhang C,Li WS,Lun LD

更新日期：1997-02-01 00:00:00

abstract：:It has been over 40 years since the initial clinical application of a cardiac pacemaker. Currently, approximately 300 per million patients in the United States and Europe are kept alive owing to the benefit of implantable pacemakers. Recently, the Japanese Cardiac Pacing Society and the Japanese Society of Artificial ...

journal_title：Artificial organs

authors： Kojima R

更新日期：1994-01-01 00:00:00

abstract：:The flow of blood as a viscous, Newtonian, incompressible liquid in an expanding spherical cavity with a ball-type inlet valve was examined. This type of flow can serve as a model of the phase of ventricular diastole in a sac-type artificial heart. The critical values of Reynolds numbers at which flow interruption beh...

journal_title：Artificial organs

authors： Starobin IM,Zaĭko VM

更新日期：1983-02-01 00:00:00

abstract：:As known from patients with pulsatile ventricular assist devices (VADs), early mobilization, physical exercise, and return to normal life are essential for optimal recovery. Recently, implantable rotary pumps became available for extended left ventricular support as bridges to transplantation. Modified procedures are ...

journal_title：Artificial organs

authors： Wieselthaler GM,Schima H,Dworschak M,Quittan M,Nuhr M,Czerny M,Seebacher G,Huber L,Grimm M,Wolner E

更新日期：2001-05-01 00:00:00

abstract：:The aim of the present study was to compare the effects of ProTaper Gold, WaveOne Gold, ProTaper Universal, and WaveOne instruments on the amount of apically extruded debris. Eighty mandibular premolar teeth with straight root canals were selected and assigned to four groups (n = 20). The root canals were instrumented...

journal_title：Artificial organs

authors： Karataş E,Ersoy İ,Gündüz HA,Uygun AD,Kol E,Çakıcı F

更新日期：2016-08-01 00:00:00

abstract：:Existing peritoneal dialysis (PD) solutions were formulated for the maintenance of fluid and electrolyte balance, correction of metabolic acidosis, and the removal of metabolic waste products. Solutions currently in development are designed to improve biocompatibility by neutralizing pH and reducing glucose degradatio...

journal_title：Artificial organs

authors： Martis L,Chen C,Moberly JB

更新日期：1998-01-01 00:00:00

abstract：:A totally implantable centrifugal artificial heart has been developed in which a pivot bearing supported centrifugal pump is used as a blood pump. The following have been adopted as blood contacting materials in our pump: titanium alloy (Ti-6A1-4V) for the housing and impeller, alumina ceramic (Al2O3) for the male piv...

journal_title：Artificial organs

authors： Takami Y,Yamane S,Makinouchi K,Niimi Y,Sueoka A,Nosé Y

更新日期：1998-09-01 00:00:00

abstract：:Replacing the renal excretion of low molecular weight proteins (LMWP) by extracorporeal dialysis (dialysis) treatment poses technological challenges. Hemodialyzers with sieving coefficients for LMWP that match or even exceed those of the glomerular membrane barrier are commercially available; however, the associated l...

journal_title：Artificial organs

authors： Glancey G

更新日期：2020-10-01 00:00:00

abstract：:Liposome-encapsulated hemoglobin (LEH) was proven to be protective in cerebral ischemia/reperfusion injury. The present study evaluated LEH in a rat model of permanent middle cerebral artery (MCA) occlusion to clarify its effect during ischemia and reperfusion. Five minutes after thread occlusion of the MCA, rats were...

journal_title：Artificial organs

authors： Kawaguchi AT,Kurita D,Furuya H,Yamano M,Ogata Y,Haida M

更新日期：2009-02-01 00:00:00

abstract：:To assess the influence of hydration state on plasma volume (PV) changes during ultrafiltration, 11 clinically normhydrated patients on maintenance hemodialysis were studied intraindividually during 2 hydration states differing by 2-15% of lean body mass (LBM). Plasma volume was measured continually during a 15-min ul...

journal_title：Artificial organs

authors： Wizemann V,Leibinger A,Mueller K,Nilson A

更新日期：1995-05-01 00:00:00

abstract：:A 36-year-old female was treated successfully by hemoperfusion over Amberlite XAD-4 resin after ingestion of 40 gm of meprobamate. Hemoperfusion was started five hours after the ingestion. At that time the patient was in deep coma. The patient was treated by hemoperfusion for five hours, at the end of which time she w...

journal_title：Artificial organs

authors： Freund LG

更新日期：1981-02-01 00:00:00

abstract：:The E4T is a totally implantable total artificial heart (TAH) resulting from many years of research work at the Cleveland Clinic Foundation (CCF) and Nimbus, Inc. It consists of four implanted subsystems: the pumping unit, the variable volume device, the transcutaneous transformer, and the internal battery. The pumpin...

journal_title：Artificial organs

authors： Smith WA,Hete BF,Kiraly RJ,Fujimoto LK,Jacobs GB,Ishikawa M,Butler K,Nosé Y

更新日期：1988-10-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB) is required in some lung transplantation (LTx) operations. However, it increases risks of bleeding and early graft dysfunction. We report our experiences of replacing CPB with heparin-bound extracorporeal membrane oxygenation (ECMO) in LTx operations. If extracorporeal circulation was anti...

journal_title：Artificial organs

authors： Ko WJ,Chen YS,Lee YC

更新日期：2001-08-01 00:00:00

abstract：:Infusion into rats of the polycation hexadimethrine (HDM) leads to onset of massive proteinuria, which recovers when the infusion is stopped. Several lines of evidence indicate that the proteinuria results from binding of HDM to polyanions of the glomerular filter, with neutralization of shielding of their charges. To...

journal_title：Artificial organs

authors： Hunsicker LG,Bertolatus JA

更新日期：1987-12-01 00:00:00

abstract：:In clinical settings, no method has been established to examine the fatigue of a latissimus dorsi muscle (LDM) preconditioned for cardiomyoplasty. We examined the feasibility of measuring muscle stiffness (tactile stiffness) to evaluate muscle fatigue in situ using our tactile sensor. We stimulated canine LDM with bur...

journal_title：Artificial organs

authors： Inaba H,Miyaji K,Kaneko Y,Ohtsuka T,Ezure M,Tambara K,Takamoto S,Omata S

更新日期：2000-10-01 00:00:00

abstract：:The effect of blood hematocrit (HCT) on a noninvasive flow estimation algorithm was examined in a centrifugal implantable rotary blood pump (iRBP) used for ventricular assistance. An average flow estimator, based on three parameters, input electrical power, pump speed, and HCT, was developed. Data were collected in a ...

journal_title：Artificial organs

authors： Malagutti N,Karantonis DM,Cloherty SL,Ayre PJ,Mason DG,Salamonsen RF,Lovell NH

更新日期：2007-01-01 00:00:00

abstract：:The postdialysis levels of serum sodium concentration, urea concentration, and osmolality, as well as the magnitude of both transcellular fluid shifts and sodium removal, were predicted based on computer modeling without measuring body fluid volumes. A 4-h hemodialysis was performed in five patients at a constant ultr...

journal_title：Artificial organs

authors： Kimura G,Van Stone JC,Bauer JH

更新日期：1983-11-01 00:00:00

abstract：:Thyrotoxic crisis (thyroid storm) is a life-threatening condition. Standard therapy is based on thiamazole, prednisolone, and nonselective beta-blockers. Extracorporeal plasmapheresis is an additional tool for removing circulating thyroxine in patients who do not respond quickly to conventional standard therapy. As th...

journal_title：Artificial organs

authors： Koball S,Hickstein H,Gloger M,Hinz M,Henschel J,Stange J,Mitzner S

更新日期：2010-02-01 00:00:00

abstract：:Nonpulsatile blood pumps are mainly used in extracorporeal life support systems. Although pulsating blood flow is known to be physiological, a pulsatile pump is not commonly applied in a circuit with a membrane oxygenator because of damage to the blood cells. The hypothesis that the placement of a pressure-relieving c...

journal_title：Artificial organs

authors： Kim TS,Sun K,Lee KB,Lee HW,Baek KJ,Park SY,Son HS,Kim KT,Kim HM

更新日期：2004-12-01 00:00:00