Numerical modeling of blood flow in the ventricular cavity of the artificial heart.

abstract：:Patients receiving mechanical circulatory support often present with heightened inflammation and free radical production associated with pre-existing conditions in addition to that which is due to blood interactions with nonbiological surfaces. The aim of this experimental laboratory study was to assess the deformabil...

journal_title：Artificial organs

authors： McNamee AP,Horobin JT,Tansley GD,Simmonds MJ

更新日期：2018-02-01 00:00:00

abstract：:Aseptic joint loosening is a key factor that reduces the life span of arthroplasty. There are currently few effective treatments for joint loosening except surgical revision. We explored the inhibitory effects of tumor necrosis factor (TNF)-alpha-targeted small interfering RNA (siRNA) on particle-induced inflammatory ...

journal_title：Artificial organs

authors： Qin CQ,Ding Y,Huang DS,Xu J,Ma RF,Huang JB

更新日期：2011-07-01 00:00:00

abstract：:A rise in intracellular calcium concentration in erythrocytes has multiple effects on these cells. The purpose of this study was to determine the changes of calcium content in red blood cells (RBCs) and of echinocyte percentages in uremic patients during hemodialysis sessions. In 30 uremic patients under hemodialysis,...

journal_title：Artificial organs

authors： Agroyannis B,Kopelias I,Fourtounas C,Paraskevopoulos A,Tzanatos H,Dalamangas A,Mallas E

更新日期：2001-06-01 00:00:00

abstract：:Tissue engineering utilizes an interdisciplinary approach to generate constructs for the treatment and repair of diseased organs. Generation of small vessels as vascular grafts or as envisioned central vessel for vascularized constructs is still a challenge. Here, the decellularization of porcine vessels by a non-dete...

journal_title：Artificial organs

authors： Eyre K,Samper E,Haverich A,Hilfiker A,Andrée B

更新日期：2020-10-01 00:00:00

abstract：:We report on 10 patients with acute renal involvement in Hantaan virus infection observed at the Department of Nephrology, Faculty of Medicine, Skopje, Republic of Macedonia, during a period of 3 years (October 1987-July 1990). Eight patients were male and 2 were female, aged 37.5 +/- 4.8 years. The diagnosis of Hanta...

journal_title：Artificial organs

authors： Polenaković M,Grcevska L,Gerasimovska-Tanevska V,Oncevski A,Dzikova S,Cakalaroski K,Masin G

更新日期：1995-08-01 00:00:00

abstract：:Atrial connections in a single-unit total artificial heart (TAH) may be difficult to make because of the rigidity of the device and the fixed position of the atrial inlets. We developed a technique to separate the natural atrial borders in an experimental implantation of a unitary TAH. In this technique, the interatri...

journal_title：Artificial organs

authors： Frazier OH,Matsuwaka R,Parnis SM,Furusho N,McGee MG,Fuqua JM

更新日期：1995-08-01 00:00:00

abstract：:The power-law based models for predicting shear-induced hemolysis are widely used in the optimization design of blood-contacting devices. However, this category of models has fallen short of accuracy when compared with the results of the in vitro experiments. The aim of this study is to develop an alternative model fr...

journal_title：Artificial organs

authors： Li H,Ruan X,Qian W,Fu X

更新日期：2014-12-01 00:00:00

abstract：:Cell exclusion is the phenomenon whereby the hematocrit and viscosity of blood decrease in areas of high stress. While this is well known in naturally occurring Poiseuille flow in the human body, it has never previously been shown in Couette flow, which occurs in implantable devices including blood pumps. The high-she...

journal_title：Artificial organs

authors： Leslie LJ,Marshall LJ,Devitt A,Hilton A,Tansley GD

更新日期：2013-03-01 00:00:00

abstract：:The aim of this meta-analysis was to determine whether pulsatile perfusion during cardiac surgery has a lesser effect on renal dysfunction than nonpulsatile perfusion after cardiac surgery in randomized controlled trials. MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials were used to identify ava...

journal_title：Artificial organs

authors： Nam MJ,Lim CH,Kim HJ,Kim YH,Choi H,Son HS,Lim HJ,Sun K

更新日期：2015-09-01 00:00:00

abstract：:Our objective was to assess the effect of nitric oxide added to the sweep gas of the oxygenator during cardiopulmonary bypass (CPB) in infants on platelet count, platelet function, clinical outcomes, and safety. A randomized, double-blinded, placebo-controlled clinical trial in infants less than a year of age undergoi...

journal_title：Artificial organs

authors： Niebler RA,Chiang-Ching H,Daley K,Janecke R,Jobe SM,Mitchell ME,Varner C,Woods K,Scott JP

更新日期：2020-08-01 00:00:00

abstract：:Doppler ultrasound is a noninvasive technique for monitoring moving objects such as flowing blood while ignoring stationary objects such as shunt tubing. A Doppler system was investigated to determine its sensitivity in detecting particulate release in blood during hemodialysis. Seven hemodialysis procedures with dogs...

journal_title：Artificial organs

authors： Badylak SF,Ash SR,Thornhill JA,Carr DJ

更新日期：1984-05-01 00:00:00

abstract：:Insufficient unloading of the left ventricle with blood stagnation is a main cause of unsuccessful left ventricular (LV) recovery during percutaneous cardiopulmonary support (PCPS). The purpose of this investigation was to evaluate the effectiveness of transaortic catheter venting (TACV) for LV unloading. Six adult mo...

journal_title：Artificial organs

authors： Shibuya M,Kitamura M,Kurihara H,Kikuchi C,Endo M,Koyanagi H

更新日期：1997-07-01 00:00:00

abstract：:Protein adsorption and platelet adhesion are two important biological processes arising at the blood prosthetic interface. The effect of certain antibiotics, namely, neomycin, gentamicin, ampicillin, penicillin-G, and streptomycin to modulate the albumin polycarbonate surface interaction was investigated using 125I al...

journal_title：Artificial organs

authors： Chandy T,Sharma CP

更新日期：1988-04-01 00:00:00

abstract：:We made miniature modules filled with artificial oxygenator hollow fibers and conducted a simple experiment to study the effect of different membrane structures on the blood. Three types of modules were made: one filled with polyolefin, one filled with polypropylene, and a blank module. The 3 modules were connected th...

journal_title：Artificial organs

authors： Nishida H,Shibuya M,Endo M,Koyanagi H

更新日期：1996-12-01 00:00:00

abstract：:We aim to evaluate clinical outcomes of emergent extracorporeal membrane oxygenation (ECMO) implantation in newborns with life-threatening meconium aspiration syndrome (MAS) in peripheral hospitals with Hub and Spoke (HandS) setting. We retrospectively reviewed all neonates presenting with MAS, with no other comorbidi...

journal_title：Artificial organs

authors： Fichera D,Zanella F,Fabozzo A,Doglioni N,Trevisanuto D,Lolli E,Vida V,Ceccherini E,Ebraico A,Stellin G,Padalino M

更新日期：2019-01-01 00:00:00

abstract：:A centrifugal blood pump with a double pivot impeller and an eccentric inlet port is being developed as an implantable artificial heart by the Baylor College of Medicine and Miwatec Co. Ltd. Flow visualization measurements were conducted to compare the flow around the pivot for two impeller operational modes: the top ...

journal_title：Artificial organs

authors： Yamane T,Kodama T,Nishida M,Maruyama O,Yamamoto Y,Shinohara T,Motomura T,Nosé Y

更新日期：2006-01-01 00:00:00

abstract：:The combination of plasma exchange and continuous hemofiltration was applied to patients with acute liver failure, and its clinically advantageous effects were evaluated. This procedure was found to be a powerful approach in decreasing patient morbidity; however, the effect was temporary and the patients finally died....

journal_title：Artificial organs

authors： Matsubara S

更新日期：1994-05-01 00:00:00

abstract：:In a healthy human cardiac system, a large asymmetric clockwise vortex present in the left ventricle (LV) efficiently diverts the filling jet from the mitral annulus to the left ventricular outflow track. However, prior clinical studies have shown that artificial mitral valve replacement can affect the formation of ph...

journal_title：Artificial organs

authors： Tan SG,Hon JKF,Nguyen YN,Kim S,Leo HL

更新日期：2020-12-01 00:00:00

abstract：:In this study, a series of natural biodegradable materials in the form of chitosan (C)-alginate (A)-hyaluronate (H) complexes are evaluated as tissue-engineering scaffolds. The weight ratio of C/A is 1 : 1 or 1 : 2. Sodium hyaluronate is mixed in 2%. The complexes can be cast into films or fabricated as scaffolds. The...

journal_title：Artificial organs

authors： Hsu SH,Whu SW,Hsieh SC,Tsai CL,Chen DC,Tan TS

更新日期：2004-08-01 00:00:00

abstract：:In a calf model, 3 standard and 3 heparin coated intraaortic balloons (IAB) were inserted and left deflated in the descending aorta during 20 min to simulate balloon rupture. At the end of the experiment, the IAB were examined, and 3 samples of each were collected for scanning electron microscopy (SEM) analysis. None ...

journal_title：Artificial organs

authors： Mueller XM,Tevaearai HT,Hayoz D,von Segesser LK

更新日期：1999-02-01 00:00:00

abstract：:Porcine endogenous retrovirus (PERV) genomes are present in all pig cells. In this retrospective study, we assessed PERV infectivity in 28 patients treated with an extracorporeal bioartificial liver (HepatAssist system) that includes a membrane device containing porcine hepatocytes. All patients tested negative for PE...

journal_title：Artificial organs

authors： Pitkin Z,Mullon C

更新日期：1999-09-01 00:00:00

abstract：:In a controlled European multicenter study, clinical tolerance of subcutaneously administered recombinant human erythropoietin (rh-EPO) therapy and its influence on the course of illness in 362 hemodialyzed patients (162 males, 200 females) from 16 European dialysis centers was studied. Of these, 181 patients served a...

journal_title：Artificial organs

authors： Klinkmann H,Wieczorek L,Scigalla P

更新日期：1993-04-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB), an integral part of valve surgery, is known to cause hemodilution, which can lead to a need for blood transfusion as well as a systemic inflammatory reaction. Our aim was to evaluate a reduced priming (RP) system for CPB with regard to clinical outcomes in patients undergoing valve surger...

journal_title：Artificial organs

authors： Sato K,Namura O,Sogawa M,Shimada K,Tosaka Y,Hayashi J

更新日期：2006-08-01 00:00:00

abstract：:The undulation pump total artificial heart (UPTAH) is a small implantable total artificial heart. As the UPTAH generates outflow and inflow at the same time, control of the UPTAH is very difficult. Therefore suitable control methods specifically for the UPTAH should be established. Various motor control, left-right fl...

journal_title：Artificial organs

authors： Saito I,Chinzei T,Abe Y,Ishimaru M,Mochizuki S,Ono T,Isoyama T,Iwasaki K,Kouno A,Baba A,Ozeki T,Takiura K,Tohyama T,Nakagawa H,Imachi K

更新日期：2003-01-01 00:00:00

abstract：:Hemolysis is one of the most important performance parameters of blood pumps. However, comparative in vitro evaluation of the reported hemolysis effect is difficult owing to the lack of uniformity in the test methods used. Currently, three types of formulas are generally accepted and widely used for the index of hemol...

journal_title：Artificial organs

authors： Naito K,Mizuguchi K,Nosé Y

更新日期：1994-01-01 00:00:00

abstract：:The clearance characteristics of two sizes of hemodialyzers (0.9 m2 and 1.5 m2) from the same range of products have been studied over the dialysate flow range of 500-3,000 ml/min to establish the device's overall mass transfer resistance characteristics. The results obtained demonstrate a difference in the overall ma...

journal_title：Artificial organs

authors： Allen R,Frost TH,Hoenich NA

更新日期：1995-11-01 00:00:00

abstract：:Visual prostheses are the focus of intensive research efforts to restore some measure of useful vision to blind or near-blind patients. The development of such technology is being guided to an extent by tools that simulate prosthesis behavior for healthy sighted subjects in order to assess system requirements and conf...

journal_title：Artificial organs

authors： Obeid I,Veraart C,Delbeke J

更新日期：2010-05-01 00:00:00

abstract：:Although extracorporeal membrane oxygenation (ECMO) improves oxygenation, pulmonary vascular resistance may be increased due to endothelial function impairment. Inhaled nitric oxide (iNO) is increasingly used for treatment of pulmonary hypertension after surgical repair of congenital heart defects, with or without ECM...

journal_title：Artificial organs

authors： Hermon M,Golej J,Burda G,Marx M,Trittenwein G,Pollak A

更新日期：1999-11-01 00:00:00

abstract：:The efficacy of three flushing techniques on subsequent liver function was assessed using the in vivo isolated liver perfusion model (ILPM). Livers from brain-dead mongrel dogs were flushed with cold Euro-Collins as follows: Group I, rapid in situ flushing (10 min); Group II, regular in situ flushing (45 min); Group I...

journal_title：Artificial organs

authors： Castellanos J,Toledo-Pereyra LH,Finkelstein I,Kestenberg W,Chapman M,Choudhury S

更新日期：1988-06-01 00:00:00

abstract：:Existing peritoneal dialysis (PD) solutions were formulated for the maintenance of fluid and electrolyte balance, correction of metabolic acidosis, and the removal of metabolic waste products. Solutions currently in development are designed to improve biocompatibility by neutralizing pH and reducing glucose degradatio...

journal_title：Artificial organs

authors： Martis L,Chen C,Moberly JB

更新日期：1998-01-01 00:00:00