An in vitro investigation into the hemodynamic effects of orifice geometry and position on left ventricular vortex formation and turbulence intensity.

abstract：:An increasing amount of evidence points to cerebral embolization during cardiopulmonary bypass (CPB) as the principal etiologic factor of neurologic complications. In this study, the capability of capturing and classification of gaseous emboli and pressure drop of three different membrane oxygenators (Sorin Apex, Teru...

journal_title：Artificial organs

authors： Guan Y,Palanzo D,Kunselman A,Undar A

更新日期：2009-11-01 00:00:00

abstract：:In previous studies, we presented main strategies for suspending the rotor of a mixed-flow type (centrifugal and axial) ventricular assist device (VAD), originally presented by the Institute Dante Pazzanese of Cardiology (IDPC), Brazil. Magnetic suspension is achieved by the use of a magnetic bearing architecture in w...

journal_title：Artificial organs

authors： da Silva I,Horikawa O,Cardoso JR,Camargo FA,Andrade AJ,Bock EG

更新日期：2011-05-01 00:00:00

abstract：:Magnevad II is an improved version of Magnevad I and both are fourth-generation axial flow left ventricular assist devices. A major simplification has been implemented and tested. Magnevad I used a magnetically suspended rotor requiring active axial control. Magnevad II is completely passive but otherwise similar. A s...

journal_title：Artificial organs

authors： Goldowsky M,Lafaro R,Reed G

更新日期：2005-10-01 00:00:00

abstract：:In this study two aspects of hybrid functional electrical stimulation (FES) orthoses were investigated: joint motion constraints and FES control strategies. First, the effects of joint motion constraints on the gait of normal subjects were investigated using modern motion analysis systems, including electromyogram (EM...

journal_title：Artificial organs

authors： Yang L,Granat MH,Paul JP,Condie DN,Rowley DI

更新日期：1997-03-01 00:00:00

abstract：:One hundred eighty-eight Mitroflow pericardial valves, implanted on 166 patients from March 1983 to December 1986, have been followed for a total of 4316 patients x months. Mortality rate in the first three postoperative months is approximately 10% related to noncardiac complications. One hundred forty-nine patients a...

journal_title：Artificial organs

authors： Loisance D,Hillion ML,Cachera JP

更新日期：1988-08-01 00:00:00

abstract：:Total artificial hearts (TAHs) and biventricular assist devices (BVADs) have varying levels of acceptance and reliability, and the research on both focuses on their control mechanisms. Efforts generally aim to achieve a response to physiologic demand and left/right output balance, and beneficial cardiac output (CO) an...

journal_title：Artificial organs

authors： Hall AW,Soykan O,Harken AH

更新日期：1996-03-01 00:00:00

abstract：:The optimal anticoagulation regimen for hemodialysis (HD) in patients with heparin-induced thrombocytopenia (HIT) has not been defined. Hemodiafiltration (HDF) adds a large convective component to HD, thereby changing the pharmacokinetics of most anticoagulants. Data on coagulation regimens for HDF are scant. We there...

journal_title：Artificial organs

authors： Mahieu E,Claes K,Jacquemin M,Evenepoel P,Op De Beek K,Bogaert AM,Kuypers D,Verhamme P,Meijers B

更新日期：2013-05-01 00:00:00

abstract：:Bovine pericardium is a widely utilized biomaterial. Usually, after harvesting, it is advantageous that the pericardium be immersed in glycerol to improve its shelf life. This can induce some degree of toxicity in the material. The studies were performed in compliance with the rules of ISO 10993 and OECD 487, in the b...

journal_title：Artificial organs

authors： Rodas AC,Maizato MJ,Leirner AA,Pitombo RN,Polakiewicz B,Beppu MM,Higa OZ

更新日期：2008-04-01 00:00:00

abstract：:The purpose of this paper is to review the pathways of hydrogen ion production and removal due to intermediary metabolism. The principal method of analysis employed was one based on a theoretical approach because it is the most accurate and has the broadest application. In the absence of hypoxia and insulin deficiency...

journal_title：Artificial organs

authors： Halperin ML

更新日期：1982-11-01 00:00:00

abstract：:Cybernetics-based concepts can allow for complete independence for paralyzed individuals, including sensory motor recovery. Spinal cord injuries are responsible for a huge stress on health and a financial burden to society. This article focuses on novel procedures such as functional diagnosis for paraplegics and tetra...

journal_title：Artificial organs

authors： Varoto R,Cliquet A Jr

更新日期：2015-10-01 00:00:00

abstract：:A magnetically levitated (maglev) centrifugal blood pump (CBP), intended for use as a ventricular assist device, needs to be highly durable and reliable for long-term use without any mechanical failure. Furthermore, maglev CBPs should be small enough to be implanted into patients of various size and weight. We have de...

journal_title：Artificial organs

authors： Asama J,Shinshi T,Hoshi H,Takatani S,Shimokohbe A

更新日期：2006-03-01 00:00:00

abstract：:The objective of this study was to evaluate an alternative neonatal extracorporeal life support (ECLS) circuit with a RotaFlow centrifugal pump and Better-Bladder (BB) for hemodynamic performance and gaseous microemboli (GME) capture in a simulated neonatal ECLS system. The circuit consisted of a Maquet RotaFlow centr...

journal_title：Artificial organs

authors： Spencer SB,Wang S,Woitas K,Glass K,Kunselman AR,Ündar A

更新日期：2017-01-01 00:00:00

abstract：:Over the last 5 years, 12 patients received ventricular assist devices (VADs) while in postcardiotomy cardiogenic shock. There were 7 male and 5 female patients ranging in age from 22 to 73 years (average age, 54). Eight patients underwent surgery for valve replacements, 3 for coronary artery bypass graftings, and 1 f...

journal_title：Artificial organs

authors： Murakami T,Nakayama H,Irie H,Kino K,Hisamochi K,Koomoto T,Takagaki M,Sugawara E,Senoo Y,Teramoto S

更新日期：1993-07-01 00:00:00

abstract：:It is well known that the baroreflex system is one of the most important indicators of the pathophysiology in hypertensive patients. We can check the sensitivity of the baroreflex by observing heart rate (HR) responses; however, there is no simple diagnostic method to measure the arterial behavior in the baroreflex sy...

journal_title：Artificial organs

authors： Yambe T,Imachi K,Shiraishi Y,Yamaguchi T,Shibata M,Kameyama T,Yoshizawa M,Sugita N

更新日期：2009-09-01 00:00:00

abstract：:Although several left ventricular assist devices (LVADs) have been used widely, remote monitoring of LVAD parameters has been available only recently. We present our remote monitoring experience with an axial-flow LVAD (HeartAssist-5, MicroMed Cardiovascular, Inc., Houston, TX, USA). Five consecutive patients who were...

journal_title：Artificial organs

authors： Pektok E,Demirozu ZT,Arat N,Yildiz O,Oklu E,Eker D,Ece F,Ciftci C,Yazicioglu N,Bayindir O,Kucukaksu DS

更新日期：2013-09-01 00:00:00

abstract：:The aim of this study was to investigate whether the use of a medically approved biodegradable scaffold as a solid support system would enhance graft survival following transplantation into the omental pouch in a preclinical large animal model. Six beagle dogs underwent total pancreatectomy followed by islet autotrans...

journal_title：Artificial organs

authors： Kin T,O'Neil JJ,Pawlick R,Korbutt GS,Shapiro AM,Lakey JR

更新日期：2008-12-01 00:00:00

abstract：:This study probed the changes of keratocytes cultured under simulated microgravity. Keratocytes were isolated from rabbit corneas using collagenase digestion method. Cells were seeded in a 55-mL capacity high-aspect-ratio vessel (HARV) of rotary cell culture system (RCCS) at a density of 1 x 10(4) cells/mL. Dehydrated...

journal_title：Artificial organs

authors： Chen J,Chen R,Gao S

更新日期：2007-09-01 00:00:00

abstract：:Neurologic complications during neonatal extracorporeal life support (ECLS) are associated with significant morbidity and mortality. Gaseous microemboli (GME) in the ECLS circuit may be a possible cause. Advances in neonatal circuitry may improve hemodynamic performance and GME handling leading to reduction in patient...

journal_title：Artificial organs

authors： Glass K,Trivedi P,Wang S,Woitas K,Kunselman AR,Ündar A

更新日期：2017-04-01 00:00:00

abstract：:Centrifugal pumps have been used widely as the main pump in open heart surgery to reduce damage to blood elements and to reduce the activation of the coagulation system. The purpose of this study was the evaluation and comparison of the effects of two types of centrifugal pumps and of one type of roller pump on blood ...

journal_title：Artificial organs

authors： Yoshikai M,Hamada M,Takarabe K,Okazaki Y,Yoshika M

更新日期：1996-05-01 00:00:00

abstract：:The use of electrical stimulation for denervated muscles is still considered to be a controversial issue by many rehabilitation facilities and medical professionals because prior clinical experience has shown that treating denervated muscle tissue using exponential current over a long time period constitutes an imposs...

journal_title：Artificial organs

authors： Kern H,Hofer C,Strohhofer M,Mayr W,Richter W,Stöhr H

更新日期：1999-05-01 00:00:00

abstract：:The majority of cases involving the surgical treatment of congenital heart disease require implementation of cardiopulmonary bypass (CPB). However, neonates and infants are particularly prone to serious complications associated with CPB as a result of capillary leak due to cardiovascular failure. These complications a...

journal_title：Artificial organs

authors： Schnoering H,Arens J,Detering SM,Sachweh JS,Goetzenich A,Schmitz-Rode T,Steinseifer U,Vazquez-Jimenez JF

更新日期：2013-06-01 00:00:00

abstract：:Molecular biology has been moving swiftly toward clarifying the entire genome of organisms, including human. The human genome efforts that promote this transaction are characterized by the large-scale, high throughput production of data about the structure of the genome of the molecular level and its computer-assisted...

journal_title：Artificial organs

authors： Matsubara K

更新日期：1996-08-01 00:00:00

abstract：:As known from patients with pulsatile ventricular assist devices (VADs), early mobilization, physical exercise, and return to normal life are essential for optimal recovery. Recently, implantable rotary pumps became available for extended left ventricular support as bridges to transplantation. Modified procedures are ...

journal_title：Artificial organs

authors： Wieselthaler GM,Schima H,Dworschak M,Quittan M,Nuhr M,Czerny M,Seebacher G,Huber L,Grimm M,Wolner E

更新日期：2001-05-01 00:00:00

abstract：:Clinically, the percutaneous transcatheter aortic valve (TAV) has been reported to be deformed in a noncircular configuration after its implant. The deformation is universal and various, and it leads to serious leakage and durability problems. Even in the same deformation, the leaflets made in different tissue thickne...

journal_title：Artificial organs

authors： Feng W,Yang X,Liu Y,Fan Y

更新日期：2017-08-01 00:00:00

abstract：:Many types of rotary blood pumps and pump control methods have recently been developed with the goal of clinical use. From experiments, we know that pump flow spontaneously increases during exercise without changing pump control parameters. The purpose of this study was to determine the hemodynamics associated with th...

journal_title：Artificial organs

authors： Akimoto T,Yamazaki K,Litwak P,Litwak KN,Tagusari O,Mori T,Antaki JF,Kameneva MV,Watach MJ,Umezu M,Tomioka J,Kormos RL,Koyanagi H,Griffith BP

更新日期：1999-08-01 00:00:00

abstract：:In patients undergoing exchange-transfusion with hemoglobin (Hb)-based oxygen (O₂) carriers (HBOC), native Hb coexists with newly transfused Hb. The two Hb types share the same arterial and venous PO₂, but their affinities for O₂ vary. A simple spreadsheet model is described aiming at evaluating the contribution of ea...

journal_title：Artificial organs

authors： Samaja M,Terraneo L

更新日期：2012-02-01 00:00:00

abstract：:What the most causative factor affecting hemolysis is still controversial. To resolve this problem, we investigated the relationship between hemolysis and heat generation in six types of centrifugal blood pumps (Bio-Pump, Delphin, Capiox, Nikkiso, Isoflow, and Toyobo). The analyzed parameters were index of hemolysis i...

journal_title：Artificial organs

authors： Araki K,Taenaka Y,Masuzawa T,Tatsumi E,Wakisaka Y,Watari M,Nakatani T,Akagi H,Baba Y,Anai H

更新日期：1995-09-01 00:00:00

abstract：:Changing financial incentives have strongly influenced dosing patterns of recombinant human erythropoietin (rHuEPO) since its introduction in 1989. Although guidelines for prescribing rHuEPO exist, the extent to which they are adhered to is unknown. Using a retrospective cohort observational study design, the factors ...

journal_title：Artificial organs

authors： Thamer M,Richard CM,Klinkmann J,Ivanovich P,Lang G,Cotter DJ

更新日期：2000-02-01 00:00:00

abstract：:This article reviews the clinical, biological, radiological, and pathological procedures and their respective indications for the practical diagnosis of the following various histological patterns of renal osteodystrophy: osteitis fibrosa due to parathyroid hormone (PTH) hypersecretion: osteomalacia or rickets due to ...

journal_title：Artificial organs

authors： Fournier A,Oprisiu R,Hottelart C,Yverneau PH,Ghazali A,Atik A,Hedri H,Said S,Sechet A,Rasolombololona M,Abighanem O,Sarraj A,El Esper N,Moriniere P,Boudailliez B,Westeel PF,Achard JM,Pruna A

更新日期：1998-07-01 00:00:00

abstract：:The aims of this study were to investigate whether introducing an interphase interval (IPI) to biphasic pulses during stimulation of the dorsiflexor muscles would affect force production and to determine whether the IPI effect is dependent on electrode position. Twelve healthy volunteers participated in the study. Eac...

journal_title：Artificial organs

authors： Springer S,Braun-Benyamin O,Abraham-Shitreet C,Becher M,Laufer Y

更新日期：2014-11-01 00:00:00