Magnevad status of design improvements human blood results and preliminary sheep trial.

abstract：:Recent studies show that oxytocin has various effects on cellular behaviors. Oxytocin is reported to stimulate cardiomyogenesis of embryonic stem cells and endothelial cell proliferation. Mesenchymal stem cells (MSCs) are widely used for cardiac repair, and we elucidated the effect of oxytocin on umbilical cord derive...

journal_title：Artificial organs

authors： Kim YS,Kwon JS,Hong MH,Kim J,Song CH,Jeong MH,Cho JG,Park JC,Kang JC,Ahn Y

更新日期：2010-06-01 00:00:00

abstract：:The majority of cases involving the surgical treatment of congenital heart disease require implementation of cardiopulmonary bypass (CPB). However, neonates and infants are particularly prone to serious complications associated with CPB as a result of capillary leak due to cardiovascular failure. These complications a...

journal_title：Artificial organs

authors： Schnoering H,Arens J,Detering SM,Sachweh JS,Goetzenich A,Schmitz-Rode T,Steinseifer U,Vazquez-Jimenez JF

更新日期：2013-06-01 00:00:00

abstract：:To study the microvessels in bulbar conjunctiva, we conducted an experiment in goat with a pneumatically driven left heart bypass pump, which was replaced with an undulation pump-left ventricle assist device for 9 days. Three flow patterns were tested: complete pulsatile, continuous, and percentage of pulsatile. We st...

journal_title：Artificial organs

authors： Dobsák P,Novakova M,Baba A,Vasku J,Isoyama T,Saito I,Abe Y,Chinzei T,Imachi K

更新日期：2006-06-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB), an integral part of valve surgery, is known to cause hemodilution, which can lead to a need for blood transfusion as well as a systemic inflammatory reaction. Our aim was to evaluate a reduced priming (RP) system for CPB with regard to clinical outcomes in patients undergoing valve surger...

journal_title：Artificial organs

authors： Sato K,Namura O,Sogawa M,Shimada K,Tosaka Y,Hayashi J

更新日期：2006-08-01 00:00:00

abstract：:Continuous hemodiafiltration (CHDF) has been performed for the treatment of severe acute pancreatitis. Phospholipase A2 (PLA2) is one of the important mediators which exacerbate acute pancreatitis, but whether PLA2 can be removed by CHDF is unclear. In this study, the kinetics of group IB and group IIA PLA2 was examin...

journal_title：Artificial organs

authors： Suzuki M,Okahisa T,Sogabe M,Iwaki H,Okita Y,Ohnishi Y,Ito S

更新日期：2007-05-01 00:00:00

abstract：:A physiological controller is a key component to optimize the performance of left ventricular assist devices (LVADs) from short term to long term (10-20 years). The difficulties of its design lie in the inaccurate modeling of any particular human cardiovascular system because of limited knowledge, the large fluctuatio...

journal_title：Artificial organs

authors： Wu Y,Allaire PE,Tao G,Adams M,Liu Y,Wood H,Olsen DB

更新日期：2004-10-01 00:00:00

abstract：:Electrolyzed water accelerated the healing of full-thickness cutaneous wounds in rats, but only anode chamber water (acid pH or neutralized) was effective. Hypochlorous acid (HOCl), also produced by electrolysis, was ineffective, suggesting that these types of electrolyzed water enhance wound healing by a mechanism un...

journal_title：Artificial organs

authors： Yahagi N,Kono M,Kitahara M,Ohmura A,Sumita O,Hashimoto T,Hori K,Ning-Juan C,Woodson P,Kubota S,Murakami A,Takamoto S

更新日期：2000-12-01 00:00:00

abstract：:Recent reports suggest a survival advantage for dialysis patients treated by postdilutional online hemodiafiltration (OL-HDF) who achieve higher volume convective exchanges. As such, the factors associated with achieving higher convective volume exchange were determined. The convective exchange volumes during the midw...

journal_title：Artificial organs

authors： Davenport A

更新日期：2016-12-01 00:00:00

abstract：:For the last few years we have attempted to separate and isolate from biological fluids the uremic Middle Molecules (MM). The first step in the treatment of plasma is an ultrafiltration through AN69 membrane. The samples are fractionated by Sephadex G-15 chromatography into 9 peaks "a" to "i' under precise conditions ...

journal_title：Artificial organs

authors： Cueille G,Man NK,Sausse A,Farges JP,Funck-Brentano JL

更新日期：1981-01-01 00:00:00

abstract：:Using computed tomography (CT)-based preoperative planning software, we can define with good accuracy the position of a cementless hip stem inside the host bone, but previous studies suggest that the pose the surgeon achieves during freehand surgery may differ from the planned one even by some millimeters. Advances in...

journal_title：Artificial organs

authors： Reggiani B,Cristofolini L,Taddei F,Viceconti M

更新日期：2008-07-01 00:00:00

abstract：:As known from patients with pulsatile ventricular assist devices (VADs), early mobilization, physical exercise, and return to normal life are essential for optimal recovery. Recently, implantable rotary pumps became available for extended left ventricular support as bridges to transplantation. Modified procedures are ...

journal_title：Artificial organs

authors： Wieselthaler GM,Schima H,Dworschak M,Quittan M,Nuhr M,Czerny M,Seebacher G,Huber L,Grimm M,Wolner E

更新日期：2001-05-01 00:00:00

abstract：:Coil-type silicone membrane oxygenators can only be used with roller blood pumps due to the resistance from the high blood flow. Therefore, during extracorporeal membrane oxygenation (ECMO) treatment, the combination of a roller pump and an oxygenator with a high blood flow resistance will induce severe hemolysis, whi...

journal_title：Artificial organs

authors： Motomura T,Maeda T,Kawahito S,Matsui T,Ichikawa S,Ishitoya H,Kawamura M,Nishimura I,Shinohara T,Oestmann D,Glueck J,Kawaguchi Y,Sato K,Nosé Y

更新日期：2002-11-01 00:00:00

abstract：:Postoperative liver failure remains a major cause of morbidity and mortality after extensive hepatectomies. This study aims to evaluate the effectiveness of a hepatocyte bioreactor in the treatment of experimental post-hepatectomy liver failure. Our experimental model included a combination of a side-to-side portacava...

journal_title：Artificial organs

authors： Arkadopoulos N,Kostopanagiotou G,Nastos C,Papalois A,Papoutsidakis N,Kalimeris K,Defterevos G,Kanna T,Polyzois K,Kampouroglou G,Kypriotis D,Costopanagiotou C,Pafiti A,Tzanatos H,Smyrniotis V

更新日期：2011-01-01 00:00:00

abstract：:The objectives of this study were: (i) to evaluate the effects of perfusion modes (pulsatile vs. nonpulsatile) on vital organs recovery and (ii) to investigate the influences of two different perfusion modes on the homeostasis of thyroid hormones in pediatric patients undergoing cardiopulmonary bypass (CPB) procedures...

journal_title：Artificial organs

authors： Akçevin A,Alkan-Bozkaya T,Qiu F,Undar A

更新日期：2010-11-01 00:00:00

abstract：:The aim of this study was to verify if dialysis solution volumes used in patients on continuous ambulatory peritoneal dialysis (CAPD) interfere with pulmonary function and if the pulmonary volumes interfere with the lymphatic absorption of the peritoneal cavity. We submitted 10 CAPD patients with a mean age of 48 +/- ...

journal_title：Artificial organs

authors： Marmanillo CG,Pecoits-Filho RF,Romão JE Jr,Kakehashi ET,Sabbaga E,Marcondes M,Abensur H

更新日期：2001-11-01 00:00:00

abstract：:Chitosan posttreatment has been shown to be effective in prevention of calcification of the glutaraldehyde treated bovine pericardium when implanted subdermally in rats for 12 weeks. The efficacy of chitosan posttreatment in complete calcium mitigation of the glutaraldehyde treated porcine aortic valves implanted in t...

journal_title：Artificial organs

authors： Chanda J,Kuribayashi R,Abe T,Sekine S,Shibata Y,Yamagishi I

更新日期：1997-05-01 00:00:00

abstract：:To avoid using sensors with low biocompatibility and low durability in implantable total artificial heart (TAH) systems, the authors previously proposed a new method for estimating instantaneous values of flow rate and pressure head on the basis of voltage, current, and rotational speed in a motor driven centrifugal p...

journal_title：Artificial organs

authors： Tanaka A,Yoshizawa M,Abe K,Takeda H,Yambe T,Nitta S

更新日期：2003-01-01 00:00:00

abstract：:In 1993, the development began of a small axial flow blood pump, the DeBakey ventricular assist device (VAD). The material was recently converted to a titanium alloy, and a waterproof pump package was incorporated for long-term intracorporeal circulation. Thirteen intrathoracic implantations in calves were achieved. N...

journal_title：Artificial organs

authors： Tayama E,Olsen DB,Ohashi Y,Benkowski R,Morley D,Noon GP,Nosé Y,Debakey ME

更新日期：1999-12-01 00:00:00

abstract：:ABO incompatible allogeneic bone marrow transplants can be performed successfully to treat patients with leukemia or aplastic anemia. These transplants carry no great risk of rejection or graft-versus-host disease, however, some method must be used to avoid acute hemolysis at the time of infusion of ABO incompatible m...

journal_title：Artificial organs

authors： Bensinger WI

更新日期：1981-08-01 00:00:00

abstract：:We report on the most recent data confirming the angiographic and pathological efficacy of LDL-apheresis for coronary atherosclerosis of a familial hypercholesterolemia (FH) patient using collected data of a large number of cases and especially of one autopsy case. Changes in coronary artery stenosis have been assesse...

journal_title：Artificial organs

authors： Koga N,Iwata Y,Yamamoto A

更新日期：1992-04-01 00:00:00

abstract：:In order to define physiological properties of the autograft root, magnetic resonance imaging (MRI) findings relative to three different operative techniques were compared with those of control subjects. Twenty-three patients, 18/5 M/F, aged 32 ± 9 years, underwent MRI assessment of the aortic root. Patients with norm...

journal_title：Artificial organs

authors： Luciani GB,Viscardi F,Puppini G,Faggian G,Mazzucco A

更新日期：2011-12-01 00:00:00

abstract：:Polyvinyl chloride (PVC) is one of the most frequently used polymers for the manufacturing of medical devices. Limitations for its usage are based upon unfavorable surface properties of the polymer including its hydrophobicity and lack of functionalities in order to increase its versatility. To address this issue, wet...

journal_title：Artificial organs

authors： Gabriel M,Strand D,Vahl CF

更新日期：2012-09-01 00:00:00

abstract：:A computer simulation was carried out to investigate the influence of nonpulsatile left ventricular assistance on hemodynamics. A simulation circuit was constructed to represent the circulatory system. A source of current was added to denote the nonpulsatile blood pump. The left and right ventricles were replaced by v...

journal_title：Artificial organs

authors： Mitsui N,Fukunaga S,Koura Y,Morita S,Hotei H,Sueshiro M,Sueda T,Matsuura Y

更新日期：1996-05-01 00:00:00

abstract：:In this pilot study, we assessed the feasibility of using positron emission tomography (PET) imaging for in vivo measurement of skeletal muscle ventricle (SMV) tissue blood flow. In 4 dogs, with SMVs prepared from their latissimus dorsi muscle, we quantified SMV tissue blood flow by PET and related it to the tissue fl...

journal_title：Artificial organs

authors： Singh TP,Greer K,Muzik O,Hammond RL,Stephenson LW,Di Carli MF

更新日期：2001-04-01 00:00:00

abstract：:Experimental studies on the effects of scaling on the performance of centrifugal blood pumps were conducted in a closed-loop test rig. For the prototype, eight different impellers of the same outer diameter of 25 mm were tested at 1,500, 2,000, and 2,500 revolutions per minute (rpm) using blood analog as fluid medium....

journal_title：Artificial organs

authors： Wong YW,Chan WK,Yu SC,Chua LP

更新日期：2002-11-01 00:00:00

abstract：:It has previously been shown that the mixture of bicarbonate and calcium in the solutions used for continuous renal replacement therapy led to crystallization and significant changes in calcium concentration and pH. The aim of this study was to investigate the impact of bicarbonate/calcium and lactate/calcium solution...

journal_title：Artificial organs

authors： Maccariello E,Dalboni MA,Draibe SA,Rocha E,Pavão dos Santos OF,Santos B,Cendoroglo M

更新日期：2004-06-01 00:00:00

abstract：:Fibroblast cell culture was performed to evaluate cell adhesion and cell morphology on novel hydrolyzable copolymers composed of poly(D,L-lactic acid) (PDLA) macromonomer, 2-methacryloyloxyethyl phosphorylcholine (MPC), and n-butyl methacrylate. The copolymers were used as cell culture materials for regulating the int...

journal_title：Artificial organs

authors： Watanabe J,Ishihara K

更新日期：2003-03-01 00:00:00

abstract：:Transplanted allogeneic marrow grafts often fail to engraft in a lethally irradiated host. Resistance to hemopoietic allograft is a complexed phenomenon involving multiple components. To study the involvement of a hemopoietic cytokine, which was known to play a role for stem cell function, we established lines of mice...

journal_title：Artificial organs

authors： Kokai Y,Kimura H,Matsuura A,Fujimoto J

更新日期：1996-08-01 00:00:00

abstract：:Changing financial incentives have strongly influenced dosing patterns of recombinant human erythropoietin (rHuEPO) since its introduction in 1989. Although guidelines for prescribing rHuEPO exist, the extent to which they are adhered to is unknown. Using a retrospective cohort observational study design, the factors ...

journal_title：Artificial organs

authors： Thamer M,Richard CM,Klinkmann J,Ivanovich P,Lang G,Cotter DJ

更新日期：2000-02-01 00:00:00

abstract：:Early in 1956, the first model of a biological artificial liver, using a live dog's liver incorporated in a cross-hemodialyzer, was placed in an experimental animal with portocaval encephalopathy. This "biological artificial liver," a hybrid artificial liver in the present terminology, was the first in the world. In O...

journal_title：Artificial organs

authors： Hori M

更新日期：1986-06-01 00:00:00