Charged compounds of the glomerular filter and their role in normal and disordered permselectivity.

abstract：:Since the introduction of high-performance prosthetic heart valves, particularly bileaflet valves and monoleaflet valves with larger opening angles, we have observed in vivo complex leaflet motion which has not been experimentally confirmed yet. We developed a computer-controlled hydraulic mock circulator to study the...

journal_title：Artificial organs

authors： Ohta Y,Okamoto K,Sonderegger M,Dohi T,Matsumoto H,Horiuchi T

更新日期：1997-04-01 00:00:00

abstract：:A review and analysis of 5,001 neonatal venoarterial (VA) extracorporeal membrane oxygenation (ECMO) cases showed that bacterial and fungal infection occurred in 147 (2.9%) and 26 (0.6%) patients, respectively, with an overall incidence of 3.5%. Bivariate analysis was used to compare infected infants with controls, ba...

journal_title：Artificial organs

authors： Douglass BH,Keenan AL,Purohit DM

更新日期：1996-03-01 00:00:00

abstract：:The outgrowth of endothelial cells in an expanded polytetrafluoroethylene graft implanted in the canine inferior vena cava was studied by scanning electron microscopy. The adjacent endothelial cells of the vena cava started to invade the anastomotic area three days after the implantation and reached approximately the ...

journal_title：Artificial organs

authors： Ishimaru S,Berglin E,Hansson HA,Teger-Nilsson AC,William-Olsson G

更新日期：1981-11-01 00:00:00

abstract：:The design criteria of an extracorporeal circuit suitable for pulsatile flow are quite different and more entangled than for steady flow. The time and costs of the design process could be reduced if mutual influences between the pulsatile pump and other extracorporeal devices were considered without experimental trial...

journal_title：Artificial organs

authors： Pennati G,Fiore GB,Laganà K,Fumero R

更新日期：2004-02-01 00:00:00

abstract：:Although extracorporeal membrane oxygenation (ECMO) improves oxygenation, pulmonary vascular resistance may be increased due to endothelial function impairment. Inhaled nitric oxide (iNO) is increasingly used for treatment of pulmonary hypertension after surgical repair of congenital heart defects, with or without ECM...

journal_title：Artificial organs

authors： Hermon M,Golej J,Burda G,Marx M,Trittenwein G,Pollak A

更新日期：1999-11-01 00:00:00

abstract：:In this study, a series of natural biodegradable materials in the form of chitosan (C)-alginate (A)-hyaluronate (H) complexes are evaluated as tissue-engineering scaffolds. The weight ratio of C/A is 1 : 1 or 1 : 2. Sodium hyaluronate is mixed in 2%. The complexes can be cast into films or fabricated as scaffolds. The...

journal_title：Artificial organs

authors： Hsu SH,Whu SW,Hsieh SC,Tsai CL,Chen DC,Tan TS

更新日期：2004-08-01 00:00:00

abstract：:With the incidence of end-stage heart failure steadily increasing, the need for a practical total artificial heart (TAH) has never been greater. Continuous flow TAHs (CFTAH) are being developed using rotary blood pumps (RBPs), leveraging their small size, mechanical simplicity, and excellent durability. To completely ...

journal_title：Artificial organs

authors： Nestler F,Timms DL,Stevens M,Bradley AP,Wilson SJ,Kleinheyer M,Lovell N,Frazier OH,Cohn WE

更新日期：2020-06-01 00:00:00

abstract：:Turbulent blood flow in medical devices contributes to blood trauma, yet the exact mechanism(s) have not been fully elucidated. Local turbulent stresses, viscous stresses, and the rate of dissipation of the turbulent kinetic energy have been proffered as hypotheses to describe and predict blood damage. In this work, s...

journal_title：Artificial organs

authors： Ozturk M,O'Rear EA,Papavassiliou DV

更新日期：2015-12-01 00:00:00

abstract：:A microcapsule suspension, a substitute for animal blood in hemolysis tests, has been developed for evaluation of the absolute hemolytic properties of circulatory artificial organs. The microcapsule suspension was made by dispersing microcapsule slurry into an ethylene glycol sodium chloride solution. The microcapsule...

journal_title：Artificial organs

authors： Maruyama O,Yamane T,Tsunemoto N,Nishida M,Tsutsui T,Jikuya T

更新日期：1999-03-01 00:00:00

abstract：:Molecular biology has been moving swiftly toward clarifying the entire genome of organisms, including human. The human genome efforts that promote this transaction are characterized by the large-scale, high throughput production of data about the structure of the genome of the molecular level and its computer-assisted...

journal_title：Artificial organs

authors： Matsubara K

更新日期：1996-08-01 00:00:00

abstract：:To expand the usage of the centrifugal pump (CP) in open heart surgery, we performed two studies. In the first, we evaluated pulsatile flow in the CP. In vitro pump performance of the Terumo Capiox pump (TCP) and the Sarns Delphin pump (SDP) and increase of free hemoglobin (mg/dl) after driving 6 h were investigated u...

journal_title：Artificial organs

authors： Nishida H,Koyanagi H,Endo M,Suzuki S,Oshiyama H,Nojiri C,Fukasawa H,Akutsu T

更新日期：1994-09-01 00:00:00

abstract：:Transplanted allogeneic marrow grafts often fail to engraft in a lethally irradiated host. Resistance to hemopoietic allograft is a complexed phenomenon involving multiple components. To study the involvement of a hemopoietic cytokine, which was known to play a role for stem cell function, we established lines of mice...

journal_title：Artificial organs

authors： Kokai Y,Kimura H,Matsuura A,Fujimoto J

更新日期：1996-08-01 00:00:00

abstract：:Pump power loss is defined as input power that is not used for the output work of the pump. Less pump power loss means a higher pump efficiency. A common opinion is that the pump power loss is closely related to heat generation of the pump, which may affect not only the endurance of pump materials, but also blood dama...

journal_title：Artificial organs

authors： Takami Y,Nakazawa T,Makinouchi K,Glueck J,Ohara Y,Benkowski RJ,Nosé Y

更新日期：1996-07-01 00:00:00

abstract：:We have made an eccentric roller type total artificial heart (ERTAH). The ERTAH is a positive-displacement device comparable to a DeBakey roller pump. Its left and right outputs are determined by the size of its blood chambers, and the ratio of its left and right output is almost constant. We focused on an interatrial...

journal_title：Artificial organs

authors： Wada H,Fukunaga S,Watari M,Sakai H,Sugawara Y,Ochikubo H,Imai K,Shibamura H,Orihashi K,Sueda T,Matsuura Y

更新日期：1999-08-01 00:00:00

abstract：:Artificial oxygen (O2 ) carriers were reported to be protective in ischemia/reperfusion (I/R) in various organs including the heart. In the current study, 20 rats underwent ligation (MI) of the left anterior descending artery, were treated with 10 mL/kg of PEGylated carboxyhemoglobin bovine (SANGUINATE, S+, n = 10) or...

journal_title：Artificial organs

authors： Kawaguchi AT,Salybekov AA,Yamano M,Kitagishi H,Sekine K,Tamaki T

更新日期：2018-12-01 00:00:00

abstract：:Monoclonal antibodies for targeting cytotoxic conjugates to tumor cells are currently being evaluated together with extracorporeal affinity adsorption. The aim of the adsorption was to reduce undesired side effects in normal organs and to increase the tumor-to-normal tissue ratios. This technique is also applicable to...

journal_title：Artificial organs

authors： Mårtensson L,Nilsson R,Sjögren HO,Strand SE,Tennvall J

更新日期：2007-04-01 00:00:00

abstract：:We reviewed the role of the BioMedicus pump in the reduction of neurologic complications following the repair of Type 1 and Type 2 thoracoabdominal aortic aneurysms. Since 1991, we have used several different methods for the repair of thoracoabdominal aortic aneurysms including simple cross-clamping, selective use of ...

journal_title：Artificial organs

authors： Safi HJ

更新日期：1996-06-01 00:00:00

abstract：:In this study, we have developed an implantable electronics unit (IEU) for driving an undulation pump-left ventricular assist device (UP-LVAD). The IEU consists of a pump driver, three series-connected lithium ion batteries (1800 mAh), a charger, and a transcutaneous information transmission system. These electronic s...

journal_title：Artificial organs

authors： Okamoto E,Makino T,Inoue Y,Tanaka S,Yasuda T,Nakamura M,Saito I,Abe Y,Chinzei T,Isoyama T,Mochiizuki S,Imachi K,Mitamura Y

更新日期：2006-05-01 00:00:00

abstract：:This article describes a new powering system for implantable medical devices that could significantly increase their lifetime. The idea is based on the substitution of the usual implantable device battery for an electric accumulator (rechargeable battery), which is fed by the electric power generated by a photovoltaic...

journal_title：Artificial organs

authors： Algora C,Peña R

更新日期：2009-10-01 00:00:00

abstract：:One hundred and seventy-two patients at The Methodist Hospital in Houston, Texas, were placed on BioMedicus centrifugal ventricular support. One hundred thirty-nine patients were male and 33 were female with a mean age of 59.7 years. Reasons for support were postcardiotomy cardiac failure (129 patients), cardiac allog...

journal_title：Artificial organs

authors： Noon GP,Ball JW Jr,Papaconstantinou HT

更新日期：1995-07-01 00:00:00

abstract：:This work presents results of preliminary studies concerning application of magnetic bearing in a ventricular assist device (VAD) being developed by Dante Pazzanese Institute of Cardiology-IDPC (São Paulo, Brazil). The VAD-IDPC has a novel architecture that distinguishes from other known VADs. In this, the rotor has a...

journal_title：Artificial organs

authors： Horikawa O,de Andrade AJ,da Silva I,Bock EG

更新日期：2008-04-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB) is a nonphysiologic environment for an organism. The damage of blood components may also lead to organ dysfunction, some-times recognized as postperfusion syndrome. One possible way to diminish the risk of these complications would be to reduce the thorombogenicity and to improve the bioco...

journal_title：Artificial organs

authors： Horimoto H,Kondo K,Asada K,Sasaki S

更新日期：1996-08-01 00:00:00

abstract：:This article reviews the clinical, biological, radiological, and pathological procedures and their respective indications for the practical diagnosis of the following various histological patterns of renal osteodystrophy: osteitis fibrosa due to parathyroid hormone (PTH) hypersecretion: osteomalacia or rickets due to ...

journal_title：Artificial organs

authors： Fournier A,Oprisiu R,Hottelart C,Yverneau PH,Ghazali A,Atik A,Hedri H,Said S,Sechet A,Rasolombololona M,Abighanem O,Sarraj A,El Esper N,Moriniere P,Boudailliez B,Westeel PF,Achard JM,Pruna A

更新日期：1998-07-01 00:00:00

abstract：:The polymer poly(ε-caprolactone) (PCL) has been used in the biomaterial field for its relatively inexpensive price and suitability for modification. Also, its chemical and biological properties are desirable for biomedical applications. The electrospinning process has been used for producing polymer fibers of PCL due ...

journal_title：Artificial organs

authors： Capellato P,Silva G,Popat K,Simon-Walker R,Alves Claro AP,Zavaglia C

更新日期：2020-08-01 00:00:00

abstract：:Transcatheter aortic valve (TAV) replacement has become a viable alternative to surgery for high and intermediate risk patients with severe aortic stenosis. This technology may extend to the younger and lower risk patients. In this population, long-term durability of the TAV is key. Increased leaflet mechanical stress...

journal_title：Artificial organs

authors： Stanová V,Zenses AS,Thollon L,Kadem L,Barragan P,Rieu R,Pibarot P

更新日期：2020-07-01 00:00:00

abstract：:From January 1980 through December 1990, implantation of a permanent pacemaker was performed in 34 patients following open heart surgery. The patients were divided into two groups according to the clinical indications for implantation of permanent pacemakers. Group 1 (9 patients) had surgical atrioventricular block, a...

journal_title：Artificial organs

authors： Otaki M

更新日期：1993-05-01 00:00:00

abstract：:A multi-compartment capillary membrane culture model with independently perfused three-dimensionally woven capillaries was developed for immobilization of hepatocytes in bioreactors. This enables spatial restructuring of cells and enhanced mass transfer performance with more efficient oxygenation and metabolite exchan...

journal_title：Artificial organs

authors： Gerlach J,Schnoy N,Smith MD,Neuhaus P

更新日期：1994-03-01 00:00:00

abstract：:In patients undergoing exchange-transfusion with hemoglobin (Hb)-based oxygen (O₂) carriers (HBOC), native Hb coexists with newly transfused Hb. The two Hb types share the same arterial and venous PO₂, but their affinities for O₂ vary. A simple spreadsheet model is described aiming at evaluating the contribution of ea...

journal_title：Artificial organs

authors： Samaja M,Terraneo L

更新日期：2012-02-01 00:00:00

abstract：:Cell-contracted collagen gels could provide rejection-free biomaterials for tissue engineering, but their application is limited by relatively low mechanical strength. We developed a special type I collagen construct (based on embedded fibroblasts) that was formed into a gel thread by using two anchors to constrain ge...

journal_title：Artificial organs

authors： Feng Z,Ishibashi M,Nomura Y,Kitajima T,Nakamura T

更新日期：2006-11-01 00:00:00

abstract：:Patient survival from our hemodialysis (HD) center over the past 11 years was analyzed. Four hundred four patients, 212 female and 192 male, were treated by chronic intermittent HD. Patients were offered standard acetate-cellulosic membranes of 1.0-1.3 m2. During this period 181 patients died. One hundred three patien...

journal_title：Artificial organs

authors： Polenakovik M,Sikole A,Stojcev N,Spasovski G,Amitov V,Nikolov V,Masin G,Klinkmann H

更新日期：1999-01-01 00:00:00