Hepatocyte culture between woven capillary networks: a microscopy study.

Abstract:

:A multi-compartment capillary membrane culture model with independently perfused three-dimensionally woven capillaries was developed for immobilization of hepatocytes in bioreactors. This enables spatial restructuring of cells and enhanced mass transfer performance with more efficient oxygenation and metabolite exchange. Seeding density defines cell behaviour in this model. With low densities cells attach to the membranes and flatten. Increasing density leads to spontaneous formation of aggregates which are immobilized between the capillaries.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Gerlach J,Schnoy N,Smith MD,Neuhaus P

doi

10.1111/j.1525-1594.1994.tb02181.x

subject

Has Abstract

pub_date

1994-03-01 00:00:00

pages

226-30

issue

3

eissn

0160-564X

issn

1525-1594

journal_volume

18

pub_type

杂志文章
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    doi:10.1111/j.1525-1594.1982.tb01675.x

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    更新日期:1982-08-01 00:00:00

  • Performance of baffled bubble blood oxygenators.

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    pub_type: 杂志文章

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  • Influence of Instruments Used in Root Canal Preparation on Amount of Apically Extruded Debris.

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  • Estimation of maximum ventricular elastance under assistance with a rotary blood pump.

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  • Predictive Factors Upon Discontinuation of Renal Replacement Therapy for Long-Term Chronic Dialysis and Death in Acute Kidney Injury Patients.

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  • Delivery of the bioactive gas hydrogen sulfide during cold preservation of rat liver: effects on hepatic function in an ex vivo model.

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  • Changes in albumin/platelet interaction with an artificial surface--due to a antibiotics, pyridoxal phosphate, and lymphocytes.

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  • Evaluation of platelet adhesion and activation on materials for an implantable centrifugal blood pump.

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  • Effect of cyclosporine therapy with low doses of corticosteroids on idiopathic nephrotic syndrome.

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