Selective removal of anti-acetylcholine receptor antibodies and IgG in vitro with an immunoadsorbent containing immobilized sulfathiazole.

abstract：:There has been increasing interest in the development of a hepatocyte bioreactor for the treatment of acute hepatic failure; however, little is known about the effect of hepatocyte byproducts on the viability of the cells in the bioreactor environment. We investigated the effects of increasing concentrations of bile o...

journal_title：Artificial organs

authors： Smirthwaite AD,Gaylor JD,Cousins RB,Grant MH

更新日期：1998-10-01 00:00:00

abstract：:Magnevad II is an improved version of Magnevad I and both are fourth-generation axial flow left ventricular assist devices. A major simplification has been implemented and tested. Magnevad I used a magnetically suspended rotor requiring active axial control. Magnevad II is completely passive but otherwise similar. A s...

journal_title：Artificial organs

authors： Goldowsky M,Lafaro R,Reed G

更新日期：2005-10-01 00:00:00

abstract：:Technological innovations in pediatric extracorporeal life support circuits can reduce system-related complications and may improve patients' outcome. The Deltastream DP3 (Medos Medizintechnik AG, Stolberg, Germany) is a novel rotational pump with a diagonally streamed impeller that can be used over a broad range of f...

journal_title：Artificial organs

authors： Stiller B,Houmes RJ,Rüffer A,Kumpf M,Müller A,Kipfmüller F,Köditz H,Herber Jonat S,Schmoor C,Benk C,Tibboel D,Fleck T

更新日期：2018-04-01 00:00:00

abstract：:Porcine endogenous retrovirus (PERV) genomes are present in all pig cells. In this retrospective study, we assessed PERV infectivity in 28 patients treated with an extracorporeal bioartificial liver (HepatAssist system) that includes a membrane device containing porcine hepatocytes. All patients tested negative for PE...

journal_title：Artificial organs

authors： Pitkin Z,Mullon C

更新日期：1999-09-01 00:00:00

abstract：:Modeling different treatment options before a procedure is performed is a promising approach for surgical decision making and patient care in heart valve disease. This study investigated the hemodynamic impact of different prostheses through patient-specific MRI-based CFD simulations. Ten time-resolved MRI data sets w...

journal_title：Artificial organs

authors： Hellmeier F,Nordmeyer S,Yevtushenko P,Bruening J,Berger F,Kuehne T,Goubergrits L,Kelm M

更新日期：2018-01-01 00:00:00

abstract：:In vitro cardiovascular device performance evaluation in a mock circulation loop (MCL) is a necessary step prior to in vivo testing. A MCL that accurately represents the physiology of the cardiovascular system accelerates the assessment of the device's ability to treat pathological conditions. To serve this purpose, a...

journal_title：Artificial organs

authors： Timms DL,Gregory SD,Greatrex NA,Pearcy MJ,Fraser JF,Steinseifer U

更新日期：2011-04-01 00:00:00

abstract：:It is well known that the baroreflex system is one of the most important indicators of the pathophysiology in hypertensive patients. We can check the sensitivity of the baroreflex by observing heart rate (HR) responses; however, there is no simple diagnostic method to measure the arterial behavior in the baroreflex sy...

journal_title：Artificial organs

authors： Yambe T,Imachi K,Shiraishi Y,Yamaguchi T,Shibata M,Kameyama T,Yoshizawa M,Sugita N

更新日期：2009-09-01 00:00:00

abstract：:We investigated biodegradation and biocompatibility of poly(organophosphazenes). We prepared poly(organophosphazenes) having different side chain groups. The blood compatibility of poly(organophosphazenes) containing fluorinated side groups, poly(bis[trifluoroethoxy]phosphazene) (PbFP) and poly([trifluoroethoxy][ethyl...

journal_title：Artificial organs

authors： Kawakami H,Kanezaki S,Sudo M,Kanno M,Nagaoka S,Kubota S

更新日期：2002-10-01 00:00:00

abstract：:Five typical mechanical heart valves (Starr-Edwards, Björk-Shiley convexo-concave (c-c), Björk-Shiley monostrut, Bicer-Val, and St. Jude Medical) were tested in the mitral position under the pulsatile flow condition. The test program included measurements of velocity and turbulent stresses at 5 downstream locations. T...

journal_title：Artificial organs

authors： Akutsu T,Modi VJ

更新日期：1997-10-01 00:00:00

abstract：:Extracorporeal life support (ECLS) has been increasingly utilized to manage cardiac and pulmonary dysfunction. The impact of obesity on outcomes of ECLS is poorly defined. The purpose of the study was to compare in-hospital mortality, resource use, complications, and readmissions in obese versus non-obese patients rec...

journal_title：Artificial organs

authors： Christian-Miller N,Hadaya J,Nakhla M,Sanaiha Y,Madrigal J,Emami S,Cale M,Sareh S,Benharash P

更新日期：2020-11-01 00:00:00

abstract：:The aim of this work is to construct a computational fluid dynamics model capable of simulating the transient non-Newtonian process of apheresis. A Lagrangian-Eulerian model has been developed which tracks the blood particles within a two-dimensional flow configuration. Within the Eulerian method, the fluid mass and m...

journal_title：Artificial organs

authors： De Gruttola S,Boomsma K,Poulikakos D

更新日期：2005-12-01 00:00:00

abstract：:The aim of the present study was to compare the effects of ProTaper Gold, WaveOne Gold, ProTaper Universal, and WaveOne instruments on the amount of apically extruded debris. Eighty mandibular premolar teeth with straight root canals were selected and assigned to four groups (n = 20). The root canals were instrumented...

journal_title：Artificial organs

authors： Karataş E,Ersoy İ,Gündüz HA,Uygun AD,Kol E,Çakıcı F

更新日期：2016-08-01 00:00:00

abstract：:The multi-output adaptive controller of a left ventricular assist device (LVAD) was studied by computer simulation. The controller regulated two outputs--mean aortic pressure (mAoP) and mean atrial pressure (mLAP)--by regulating vacuum pressure (input). The autoregressive models were used to describe the circulatory s...

journal_title：Artificial organs

authors： Shimooka T,Mitamura Y,Yuhta T

更新日期：1991-04-01 00:00:00

abstract：:A magnetically levitated (maglev) centrifugal blood pump (CBP), intended for use as a ventricular assist device, needs to be highly durable and reliable for long-term use without any mechanical failure. Furthermore, maglev CBPs should be small enough to be implanted into patients of various size and weight. We have de...

journal_title：Artificial organs

authors： Asama J,Shinshi T,Hoshi H,Takatani S,Shimokohbe A

更新日期：2006-03-01 00:00:00

abstract：:Aseptic joint loosening is a key factor that reduces the life span of arthroplasty. There are currently few effective treatments for joint loosening except surgical revision. We explored the inhibitory effects of tumor necrosis factor (TNF)-alpha-targeted small interfering RNA (siRNA) on particle-induced inflammatory ...

journal_title：Artificial organs

authors： Qin CQ,Ding Y,Huang DS,Xu J,Ma RF,Huang JB

更新日期：2011-07-01 00:00:00

abstract：:The generation of anaphylatoxins, particularly C5a, is important in extracorporeal circulation therapies such as granulocyte/monocyte apheresis, which activates the complement system and elevates C5a levels. However, no side effects of granulocyte/monocyte apheresis using cellulose acetate beads have been reported. To...

journal_title：Artificial organs

authors： Takeda Y,Ohba M,Ueno M,Saniabadi AR,Wakabayashi I

更新日期：2010-12-01 00:00:00

abstract：:Polyvinyl chloride (PVC) is one of the most frequently used polymers for the manufacturing of medical devices. Limitations for its usage are based upon unfavorable surface properties of the polymer including its hydrophobicity and lack of functionalities in order to increase its versatility. To address this issue, wet...

journal_title：Artificial organs

authors： Gabriel M,Strand D,Vahl CF

更新日期：2012-09-01 00:00:00

abstract：:This study evaluates the effect of poly(L-lactic acid) (PLLA) and poly(hydroxybutyrate-cohydroxyvalerate) (PHBV) bioabsorbable polymers and their blends on the induction of alteration of cell growth pattern in vitro. Vero cells were cultured on PLLA, PHBV, and different blends (100/0, 60/40, 50/50, 40/60, and 0/100). ...

journal_title：Artificial organs

authors： Santos AR Jr,Ferreira BM,Duek EA,Dolder H,Wada RS,Wada ML

更新日期：2004-04-01 00:00:00

abstract：:Thousands of ventricular assist devices (VADs) currently provide circulatory support to patients worldwide, and dozens of heart pump designs for adults and pediatric patients are under various stages of development in preparation for translation to clinical use. The successful bench-to-bedside development of a VAD inv...

journal_title：Artificial organs

authors： Throckmorton AL,Patel-Raman SM,Fox CS,Bass EJ

更新日期：2016-06-01 00:00:00

abstract：:A 68-year-old woman with fulminant hepatic failure of unknown etiology was treated with a bioartificial liver assist device. Prior to treatment, she had a number of clinical and laboratory features that suggested a hopeless outcome. Treatment was associated with a dramatic change in her mental status, and her clinical...

journal_title：Artificial organs

authors： Sussman NL,Kelly JH

更新日期：1993-01-01 00:00:00

abstract：:This work presents results of preliminary studies concerning application of magnetic bearing in a ventricular assist device (VAD) being developed by Dante Pazzanese Institute of Cardiology-IDPC (São Paulo, Brazil). The VAD-IDPC has a novel architecture that distinguishes from other known VADs. In this, the rotor has a...

journal_title：Artificial organs

authors： Horikawa O,de Andrade AJ,da Silva I,Bock EG

更新日期：2008-04-01 00:00:00

abstract：:The abdominal left ventricular assist device (ALVAD) is an order of magnitude more effective than conventional intra-aortic balloon pumping (IABP) in unloading and providing circulatory support to the failing left ventricle. This is a report of a unique case which demonstrates that in the absence of pulmonary vascular...

journal_title：Artificial organs

authors： Norman JC,Dacso CC,Reul GJ,Massin EK,Klima T,Kahan BD,Keiser JT,Cooley DA

更新日期：1978-11-01 00:00:00

abstract：:A belt worn controller and lithium-ion battery pack have been developed for use with the initial clinical trials of the Jarvik 2000 heart. Patient interface considerations, safety, and simplicity were major design inputs for the system. The controller was developed using all analog technology to avoid difficulties wit...

journal_title：Artificial organs

authors： Jarvik R,Scott V,Morrow M,Takecuhi E

更新日期：1999-06-01 00:00:00

abstract：:The combination of plasma exchange and continuous hemofiltration was applied to patients with acute liver failure, and its clinically advantageous effects were evaluated. This procedure was found to be a powerful approach in decreasing patient morbidity; however, the effect was temporary and the patients finally died....

journal_title：Artificial organs

authors： Matsubara S

更新日期：1994-05-01 00:00:00

abstract：:In this proof of principle study, we investigated the effectiveness and safety of hemodynamic support with the Intra-Ventricular Membrane Pump (IVMP). The IVMP was implanted into the apex of the left ventricle. Hemodynamic assessment was performed in six ex vivo beating porcine hearts (PhysioHeart platform). The cardi...

journal_title：Artificial organs

authors： van Dort DIM,Thannhauser J,Gommans FDH,Ten Cate TJ,Duncker DJ,Suryapranata H,Morshuis WJ,Geuzebroek GSC

更新日期：2020-12-01 00:00:00

abstract：:Small blood vessels may play a more important role in artificial heart (AH) recipients than ever suspected before. Observations of elevated total peripheral resistance, low hematocrit, reduced oncotic pressure, high circulating blood volume, and arterial pulsations with nonpulsatile devices require consideration of pe...

journal_title：Artificial organs

authors： Lübbe AS

更新日期：1988-02-01 00:00:00

abstract：:Mechanical circulatory support (MCS) devices continue to be hampered by thrombotic adverse events (AEs), a consequence of device-imparted supraphysiologic shear stresses, leading to shear-mediated platelet activation (SMPA). In advancing MCS devices from design to clinical use, in vitro circulatory loops containing th...

journal_title：Artificial organs

authors： Li M,Walk R,Roka-Moiia Y,Sheriff J,Bluestein D,Barth EJ,Slepian MJ

更新日期：2020-06-01 00:00:00

abstract：:This paper describes a new miniaturized implantable bladder controller that is composed of 4 main parts: a volume monitoring device based on the tomography approach, a fully programmable miniaturized central processor and stimulator, a bidirectional data and power link, and an external controller. The proposed system ...

journal_title：Artificial organs

authors： Sawan M,Arabi K,Provost B

更新日期：1997-03-01 00:00:00

abstract：:This article presents results from the field calculation in a model of biological tissue taking into account the electroporation process. The electroporation model used in this study was proposed and experimentally verified by Glaser et al. for planar membranes. The numerical method for field calculation is based on a...

journal_title：Artificial organs

authors： Ramos A

更新日期：2005-06-01 00:00:00

abstract：:We have been developing a new type of centrifugal pump for long-term use. The magnetically suspended centrifugal pump (MSCP) contains no shaft and seal so that long life expectancy is predicted. Paracorporeal left ventricular (LV) assist circulation between the left atrium and the descending aorta was instituted using...

journal_title：Artificial organs

authors： Yamada T,Nishimura K,Park CH,Kono S,Yuasa S,Tsukiya T,Akamatsu T,Matsuda K,Ban T

更新日期：1997-07-01 00:00:00