Cytotoxicity of bile in human Hep G2 cells and in primary cultures of rat hepatocytes.

abstract：:We aimed to investigate whether acellular endocardium can be used as a useful biomaterial for the intima of engineered small-caliber vascular grafts. Fresh endocardium was harvested from the swine left atrium and was decellularized by digestion with the decellularization solution of Triton X-100 and SDS containing DNa...

journal_title：Artificial organs

authors： Wang F,Guan X,Wu T,Qiao J,Han Z,Wu J,Yu X,You Q

更新日期：2016-12-01 00:00:00

abstract：:Recent studies show that oxytocin has various effects on cellular behaviors. Oxytocin is reported to stimulate cardiomyogenesis of embryonic stem cells and endothelial cell proliferation. Mesenchymal stem cells (MSCs) are widely used for cardiac repair, and we elucidated the effect of oxytocin on umbilical cord derive...

journal_title：Artificial organs

authors： Kim YS,Kwon JS,Hong MH,Kim J,Song CH,Jeong MH,Cho JG,Park JC,Kang JC,Ahn Y

更新日期：2010-06-01 00:00:00

abstract：:Loss of photoreceptor cells is one of the major causes of blindness. Several groups are exploring the functional replacement of photoreceptors by a retinal prosthesis. The goal of this study was to simulate the vision levels that recipients of retinal prostheses with 4 x 4, 6 x 10, and 16 x 16 electrode arrays may exp...

journal_title：Artificial organs

authors： Hayes JS,Yin VT,Piyathaisere D,Weiland JD,Humayun MS,Dagnelie G

更新日期：2003-11-01 00:00:00

abstract：:To save priming time and perform more rapid initiation of emergency cardiopulmonary bypass for acute cardiopulmonary failure, an extracorporeal circuit with a hollow-fiber oxygenator (EL-2000 for pediatric use; Kurary Co. Ltd., Osaka, Japan) was preprimed, and the gas-exchange function was evaluated after 1 year of st...

journal_title：Artificial organs

authors： Otsu T,Terasaki H,Choi H,Tajiri A,Okamoto T,Matsuyama K,Morioka T

更新日期：1992-10-01 00:00:00

abstract：:Although the debate still continues over the effectiveness of pulsatile versus nonpulsatile perfusion, it has been clearly proven that there are several significant physiological benefits of pulsatile perfusion during cardiopulmonary bypass (CPB) compared to nonpulsatile perfusion. However, the components of the extra...

journal_title：Artificial organs

authors： Undar A,Lodge AJ,Daggett CW,Runge TM,Ungerleider RM,Calhoon JH

更新日期：1998-08-01 00:00:00

abstract：:Artificial oxygen (O2 ) carriers were reported to be protective in ischemia/reperfusion (I/R) in various organs including the heart. In the current study, 20 rats underwent ligation (MI) of the left anterior descending artery, were treated with 10 mL/kg of PEGylated carboxyhemoglobin bovine (SANGUINATE, S+, n = 10) or...

journal_title：Artificial organs

authors： Kawaguchi AT,Salybekov AA,Yamano M,Kitagishi H,Sekine K,Tamaki T

更新日期：2018-12-01 00:00:00

abstract：:In this study two aspects of hybrid functional electrical stimulation (FES) orthoses were investigated: joint motion constraints and FES control strategies. First, the effects of joint motion constraints on the gait of normal subjects were investigated using modern motion analysis systems, including electromyogram (EM...

journal_title：Artificial organs

authors： Yang L,Granat MH,Paul JP,Condie DN,Rowley DI

更新日期：1997-03-01 00:00:00

abstract：:We were encouraged to investigate the reasons for large amounts of foam observed in bloodlines during hemodialysis (HD). Foam was visible in the venous air trap within the Artis Gambro dialysis device. Estimates of the extent of foam were graded (0-no foam, 10-extensive foam) by two persons that were blind to the type...

journal_title：Artificial organs

authors： Jonsson P,Lindmark L,Axelsson J,Karlsson L,Lundberg L,Stegmayr B

更新日期：2018-05-01 00:00:00

abstract：:The optimal anticoagulation regimen for hemodialysis (HD) in patients with heparin-induced thrombocytopenia (HIT) has not been defined. Hemodiafiltration (HDF) adds a large convective component to HD, thereby changing the pharmacokinetics of most anticoagulants. Data on coagulation regimens for HDF are scant. We there...

journal_title：Artificial organs

authors： Mahieu E,Claes K,Jacquemin M,Evenepoel P,Op De Beek K,Bogaert AM,Kuypers D,Verhamme P,Meijers B

更新日期：2013-05-01 00:00:00

abstract：:The multi-output adaptive controller of a left ventricular assist device (LVAD) was studied by computer simulation. The controller regulated two outputs--mean aortic pressure (mAoP) and mean atrial pressure (mLAP)--by regulating vacuum pressure (input). The autoregressive models were used to describe the circulatory s...

journal_title：Artificial organs

authors： Shimooka T,Mitamura Y,Yuhta T

更新日期：1991-04-01 00:00:00

abstract：:Neurological morbidity is a major concern in pediatric cardiac surgery. Cardiopulmonary bypass is one of the few modifiable factors affecting neurodevelopmental outcome. This study aimed to measure the incidence of abnormalities apparent by magnetic resonance imaging (MRI) after neonatal arterial switch operation usin...

journal_title：Artificial organs

authors： Durandy Y,Rubatti M,Couturier R,Rohnean A

更新日期：2011-11-01 00:00:00

abstract：:A small and light direct-drive centrifugal pump has been developed for cardiopulmonary bypass. In the development process, blood compatibility studies including a hemolysis study, an in vitro fluid dynamic performance study, and in vivo durability and feasibility studies were performed. The centrifugal pump with a 50 ...

journal_title：Artificial organs

authors： Jikuya T,Sasaki T,Aizawa T,Shiono M,Glueck JA,Smith CP,Feldman L,Sakuma I,Sekela ME,Noda T

更新日期：1992-12-01 00:00:00

abstract：:In vitro tests have shown that electric currents may lead either to relaxation or contraction of the bowel wall. Because voluntary changes of the intestinal motility could be useful in the treatment of intestinal disorders, we investigated the reactions elicited by electrostimulation of the small intestine in the inta...

journal_title：Artificial organs

authors： Moritz A,Grundfest-Broniatowski S,Ilyes L,Kasick J,Jacobs G,Olsen E,Nosé Y

更新日期：1989-04-01 00:00:00

abstract：:The major problems with existing centrifugal pumps are leakage, mechanical trauma, and thrombus formation. In consideration of these problems, a new compact centrifugal pump system was developed. The purpose of this study was to evaluate the new centrifugal pump system clinically. Ten patients underwent open heart sur...

journal_title：Artificial organs

authors： Ninomiya J,Shoji T,Tanaka S,Ikeshita M,Ochi M,Yamauchi S,Yajima T,Yamauchi H,Sugimoto T,Aizawa T

更新日期：1994-09-01 00:00:00

abstract：PURPOSE:We were led to the premise that with retrograde oxygenated blood perfusion, it would be possible to perform operations on the beating heart. METHODS:The experiment consisted of two stages: procedure 1 and 2. In procedure 1, six pigs were used. Retrograde perfusion flow was controlled to be in the range of 5.0-...

journal_title：Artificial organs

authors： Tsukioka T,Tomita S,Watanabe G,Takemura H

更新日期：2004-03-01 00:00:00

abstract：:To overcome the weak mechanical properties of cell/hydrogel composites, a poly(DL-lactic-co-glycolic acid) sandwiched adipose-derived stem cell (ADSC)/fibrin construct was fabricated using a step-by-step mold/extraction method to generate the middle smooth muscle layer of natural blood vessels. A pulse bioreactor with...

journal_title：Artificial organs

authors： Wang X,Sui S

更新日期：2011-06-01 00:00:00

abstract：:Changing financial incentives have strongly influenced dosing patterns of recombinant human erythropoietin (rHuEPO) since its introduction in 1989. Although guidelines for prescribing rHuEPO exist, the extent to which they are adhered to is unknown. Using a retrospective cohort observational study design, the factors ...

journal_title：Artificial organs

authors： Thamer M,Richard CM,Klinkmann J,Ivanovich P,Lang G,Cotter DJ

更新日期：2000-02-01 00:00:00

abstract：:Oxidative stress is crucial in red blood cell (RBC) damage induced by activated neutrophils in in vitro experiments. The aim of the study was to evaluate whether the bioincompatibility phenomena occurring during hemodialysis (HD) (where neutrophil activation with increased free radical production is well documented) m...

journal_title：Artificial organs

authors： Lucchi L,Bergamini S,Botti B,Rapanà R,Ciuffreda A,Ruggiero P,Ballestri M,Tomasi A,Albertazzi A

更新日期：2000-01-01 00:00:00

abstract：:Temporary extracorporeal membrane oxygenation (ECMO) has been established as an essential part of therapy in patients with pulmonary or cardiac failure. As physiological gaseous exchange is artificially altered in this patient group, it is debatable whether a (13) C-breath test can be carried out. In this proof of tec...

journal_title：Artificial organs

authors： Bednarsch J,Menk M,Malinowski M,Weber-Carstens S,Pratschke J,Stockmann M

更新日期：2016-07-01 00:00:00

abstract：:A computer simulation was carried out to investigate the influence of nonpulsatile left ventricular assistance on hemodynamics. A simulation circuit was constructed to represent the circulatory system. A source of current was added to denote the nonpulsatile blood pump. The left and right ventricles were replaced by v...

journal_title：Artificial organs

authors： Mitsui N,Fukunaga S,Koura Y,Morita S,Hotei H,Sueshiro M,Sueda T,Matsuura Y

更新日期：1996-05-01 00:00:00

abstract：:Fibroblast cell culture was performed to evaluate cell adhesion and cell morphology on novel hydrolyzable copolymers composed of poly(D,L-lactic acid) (PDLA) macromonomer, 2-methacryloyloxyethyl phosphorylcholine (MPC), and n-butyl methacrylate. The copolymers were used as cell culture materials for regulating the int...

journal_title：Artificial organs

authors： Watanabe J,Ishihara K

更新日期：2003-03-01 00:00:00

abstract：:The aim of this study was to evaluate the efficiency of hemoperfusion (HP) through coated resin adsorbent Synachrom E-5 in animal intoxications with organophosphate inhibitors of cholinesterases type of nerve agents. Five anesthetized dogs were intoxicated with 2 to 6 LD50 of VX substance and another 4 with 2 to 3 LD5...

journal_title：Artificial organs

authors： Monhart V,Fusek J,Brndiar M,Tlustakova M

更新日期：1994-10-01 00:00:00

abstract：:An investigation has been made into whether charcoal hemoperfusion stimulates a hyperplastic response in the liver of the normal rat. Animals underwent hemoperfusion over Norit RBX1 (Strathclyde, Glasgow, U.K.) charcoal granules using a technique which allowed perfusion in the unrestrained and conscious state. Control...

journal_title：Artificial organs

authors： Ryan CJ,Courtney JM,Wood CB,Blumgart LH

更新日期：1982-05-01 00:00:00

abstract：:Plasma procoagulant activities of factors XII, XI, IX, and VIII and plasma concentrations of factor XII antigen and high molecular weight kininogen (HMK) were determined in nine men with chronic renal failure (CRF) associated with long-standing spinal cord injury (SCI) treated with hemodialysis. The results were compa...

journal_title：Artificial organs

authors： Vaziri ND,Winer RL,Toohey J,Danviriyasup K,Alikhani S,Eltorai I,Gordon S,Paule P

更新日期：1985-05-01 00:00:00

abstract：:There is increasing evidence showing that adult stem cells are useful for tissue regeneration. Bone marrow mesenchymal stem cells (MSCs) are self-renewing and are potent in differentiating into multiple cells and tissues. To investigate the practicability of repairing burn wounds with tissue-engineered (TE) skin combi...

journal_title：Artificial organs

authors： Liu P,Deng Z,Han S,Liu T,Wen N,Lu W,Geng X,Huang S,Jin Y

更新日期：2008-12-01 00:00:00

abstract：:Secondary flow in the centrifugal blood pump helps to enhance the washout effect and to minimize thrombus formation. On the other hand, it has an adverse effect on pump efficiency. Excessive secondary flow may induce hemolytic effects. Understanding the secondary flow is thus important to the design of a compact, effi...

journal_title：Artificial organs

authors： Watanabe N,Masuda T,Iida T,Kataoka H,Fujimoto T,Takatani S

更新日期：2005-01-01 00:00:00

abstract：:An apparatus has been contructed to regulate ultrafiltration accurately during dialysis. The principle of the apparatus is that, per unit of time, exactly the same amount of dialysate is introduced into the dialyzer as is discharged from it. The apparatus consists of two isovolumetric pumps connected in line. The four...

journal_title：Artificial organs

authors： Flendrig JG,Carpay WM,Dekkers WT

更新日期：1978-05-01 00:00:00

abstract：:Extracorporeal membrane oxygenation (ECMO) is used for severe acute respiratory distress syndrome. However, available ECMO systems are large and not well designed for fast delivery, emergency implantation, and interhospital transfer. Therefore, a new miniaturized oxygenator with integrated rotary blood pump (ILIAS) wa...

journal_title：Artificial organs

authors： Pilarczyk K,Heckmann J,Lyskawa K,Strauß A,Haake N,Wiese I,Jakob H,Kamler M,Pizanis N

更新日期：2016-07-01 00:00:00

abstract：:Controlled and repeatable in vitro evaluation of cardiovascular devices using a mock circulation loop (MCL) is essential prior to in vivo or clinical trials. MCLs often consist of only a systemic circulation with no autoregulatory responses and limited validation. This study aimed to develop, and validate against huma...

journal_title：Artificial organs

authors： Gregory SD,Pauls JP,Wu EL,Stephens A,Steinseifer U,Tansley G,Fraser JF

更新日期：2020-06-01 00:00:00

abstract：:In previous studies, we presented main strategies for suspending the rotor of a mixed-flow type (centrifugal and axial) ventricular assist device (VAD), originally presented by the Institute Dante Pazzanese of Cardiology (IDPC), Brazil. Magnetic suspension is achieved by the use of a magnetic bearing architecture in w...

journal_title：Artificial organs

authors： da Silva I,Horikawa O,Cardoso JR,Camargo FA,Andrade AJ,Bock EG

更新日期：2011-05-01 00:00:00