Intrinsic coagulation pathway in end-stage renal disease associated with spinal cord injury treated with hemodialysis.

abstract：:Effect of hemodialysis (HD) on some indices of immune response was studied in nine chronic uremics. Total lymphocyte, OKT4+, and OKT8+ cell numbers significantly decreased during the first 20 min of HD, and they were decreased till the third hour of the procedure, whereas the OKT4+/OKT8+ cell number ratio did not chan...

journal_title：Artificial organs

authors： Tchórzewski H,Luciak M,Trznadel K,Majewska E,Pokoca L

更新日期：1989-06-01 00:00:00

abstract：:The development of a ventricular assist device is depicted. The seven subprograms that make up the project are described briefly. Results obtained during the clinical assay showed that the new design of the input cannula working as a false auricle provides better efficiency, as well as a certain level of autoregulatio...

journal_title：Artificial organs

authors： del Cañizo JF,Antoranz JC,Desco MM,Alvarez-Valdivielso JM,Fernandez-Caleya D,López M,Garcia-Barreno P,Duarte J

更新日期：1994-07-01 00:00:00

abstract：:Aortic wall thinness was one of the most characteristic changes observed in experimental animals under prolonged continuous flow left heart bypass. The goal of this study was to determine the roles of smooth muscle cells in the vascular remodeling process in cases demonstrating aortic wall thinness under prolonged con...

journal_title：Artificial organs

authors： Mizuno T,Nishinaka T,Ohnishi H,Tatsumi E,Tsukiya T,Oshikawa M,Shioya K,Takewa Y,Homma A,Takano H,Kitamura S,Taenaka Y

更新日期：2003-10-01 00:00:00

abstract：:The use of extracorporeal membrane oxygenator instead of standard cardiopulmonary bypass during lung transplantation is debatable. Moreover, recently, the concept of prolonged postoperative extracorporeal membrane oxygenator (ECMO) support has been introduced in many transplant centers to prevent primary graft dysfunc...

journal_title：Artificial organs

authors： Dell'Amore A,Campisi A,Congiu S,Mazzarra S,Pastore S,Dolci G,Baiocchi M,Frascaroli G

更新日期：2020-06-01 00:00:00

abstract：:The products of complement activation, including C3a, C4a, C5a, and their des Arg derivatives, have been used by many investigators as indicators of blood or foreign surface bioincompatibility, e.g., during hemodialysis. One problem encountered is that after extracorporeal circulation over some dialysis membranes very...

journal_title：Artificial organs

authors： Spencer PC,Schmidt B,Gurland HJ

更新日期：1986-02-01 00:00:00

abstract：:This paper presents an overview of the U.S. Food and Drug Administration's regulatory requirements for introducing medical device and diagnostic products into commercial distribution in the United States. For any specific product, the requirements vary depending upon the product's associated risks, classification, and...

journal_title：Artificial organs

authors： Morton WA

更新日期：1982-11-01 00:00:00

abstract：:Cybernetics-based concepts can allow for complete independence for paralyzed individuals, including sensory motor recovery. Spinal cord injuries are responsible for a huge stress on health and a financial burden to society. This article focuses on novel procedures such as functional diagnosis for paraplegics and tetra...

journal_title：Artificial organs

authors： Varoto R,Cliquet A Jr

更新日期：2015-10-01 00:00:00

abstract：:The characteristic depressed hemodynamic state and gradually declining circulatory function in Fontan patients necessitates alternative postoperative management strategies incorporating a system level approach. In this study, the single-ventricle Fontan circulation is modeled by constructing a practical in vitro bench...

journal_title：Artificial organs

authors： Dur O,Lara M,Arnold D,Vandenberghe S,Keller BB,DeGroff C,Pekkan K

更新日期：2009-11-01 00:00:00

abstract：:Since the introduction of high-performance prosthetic heart valves, particularly bileaflet valves and monoleaflet valves with larger opening angles, we have observed in vivo complex leaflet motion which has not been experimentally confirmed yet. We developed a computer-controlled hydraulic mock circulator to study the...

journal_title：Artificial organs

authors： Ohta Y,Okamoto K,Sonderegger M,Dohi T,Matsumoto H,Horiuchi T

更新日期：1997-04-01 00:00:00

abstract：:Twelve patients, 8 male and 4 female, aged from 26 to 70 years were studied. They were on hemodialysis (HD) 4 h three times weekly with cuprophan hollow fiber dialyzers (Gambro 120M) and dialysate containing 35 mEq/L of acetate. The study compares two random HD sessions on each patient. Sixty minutes prior to one rand...

journal_title：Artificial organs

authors： Grekas D,Alivanis P,Karamouzis M,Pyrpasopoulos M,Tourkantonis A

更新日期：1989-10-01 00:00:00

abstract：:We designed a 24-field array and an on-line control box that selects which and how many of 24 fields will conduct electrical charge during functional electrical stimulation. The array was made using a conductive microfiber textile, silver two-component adhesive, and the conductive ink imprint on the polycarbonate. The...

journal_title：Artificial organs

authors： Popović-Bijelić A,Bijelić G,Jorgovanović N,Bojanić D,Popović MB,Popović DB

更新日期：2005-06-01 00:00:00

abstract：:The optimal anticoagulation regimen for hemodialysis (HD) in patients with heparin-induced thrombocytopenia (HIT) has not been defined. Hemodiafiltration (HDF) adds a large convective component to HD, thereby changing the pharmacokinetics of most anticoagulants. Data on coagulation regimens for HDF are scant. We there...

journal_title：Artificial organs

authors： Mahieu E,Claes K,Jacquemin M,Evenepoel P,Op De Beek K,Bogaert AM,Kuypers D,Verhamme P,Meijers B

更新日期：2013-05-01 00:00:00

abstract：:To assess the efficiency of respiratory gas exchange in vitro through a dialysis membrane mounted inside a flat plate Kiil dialyzer, the model reactions of hydrogen peroxide reduction by a metal ion and of the carbon dioxide precipitation in the form of a carbonate in the dialysate were used. A comparison of the rates...

journal_title：Artificial organs

authors： Zborowski M

更新日期：1983-05-01 00:00:00

abstract：:This article presents computational studies on the effects of inlet guide vanes (IGVs) on the flow pattern and shear stress in a centrifugal blood pump. The effect of IGVs is to introduce a pre-swirl to fluid particles entering the impeller with the intention that the fluid particles will travel along the blade profil...

journal_title：Artificial organs

authors： Chan WK,Wong YW,Yu SC,Chua LP

更新日期：2002-06-01 00:00:00

abstract：:Patients with end-stage renal disease have a very high prevalence and extent of arterial calcification. A number of studies suggest that similar pathophysiologic mechanisms are responsible for development and progression of calcification of atherosclerotic plaque and bone formation. Fetuin-A is a potent calcification ...

journal_title：Artificial organs

authors： Kirkpantur A,Altun B,Hazirolan T,Akata D,Arici M,Kirazli S,Turgan C

更新日期：2009-10-01 00:00:00

abstract：:The DexAide right ventricular assist device (RVAD) has been developed to provide an implantable RVAD option to surgeons. The aim of this study was to determine the optimal cannula design and optimal implantation location of the DexAide RVAD in preparation for its clinical use. Separately, a HeartMate XVE left ventricu...

journal_title：Artificial organs

authors： Ootaki Y,Ootaki C,Kamohara K,Akiyama M,Cingoz F,Kopcak MW Jr,Dessoffy R,Liu J,Massiello A,Horvath D,Chen JF,Zhou Q,Benefit S,Golding LA,Fukamachi K

更新日期：2007-08-01 00:00:00

abstract：:Cell-contracted collagen gels could provide rejection-free biomaterials for tissue engineering, but their application is limited by relatively low mechanical strength. We developed a special type I collagen construct (based on embedded fibroblasts) that was formed into a gel thread by using two anchors to constrain ge...

journal_title：Artificial organs

authors： Feng Z,Ishibashi M,Nomura Y,Kitajima T,Nakamura T

更新日期：2006-11-01 00:00:00

abstract：:The E4T is a totally implantable total artificial heart (TAH) resulting from many years of research work at the Cleveland Clinic Foundation (CCF) and Nimbus, Inc. It consists of four implanted subsystems: the pumping unit, the variable volume device, the transcutaneous transformer, and the internal battery. The pumpin...

journal_title：Artificial organs

authors： Smith WA,Hete BF,Kiraly RJ,Fujimoto LK,Jacobs GB,Ishikawa M,Butler K,Nosé Y

更新日期：1988-10-01 00:00:00

abstract：:Stents are small, usually metallic tubes that are intended to prop open arteries blocked with atherosclerotic plaques. While stents have been used successfully in recent years, they still suffer from failure due to development of new tissue in stented segment (restenosis). Variations in the failure rates associated wi...

journal_title：Artificial organs

authors： Frank AO,Walsh PW,Moore JE Jr

更新日期：2002-07-01 00:00:00

abstract：:One hundred and seventy-two patients at The Methodist Hospital in Houston, Texas, were placed on BioMedicus centrifugal ventricular support. One hundred thirty-nine patients were male and 33 were female with a mean age of 59.7 years. Reasons for support were postcardiotomy cardiac failure (129 patients), cardiac allog...

journal_title：Artificial organs

authors： Noon GP,Ball JW Jr,Papaconstantinou HT

更新日期：1995-07-01 00:00:00

abstract：:Success of total artificial heart (TAH) implantation as a temporary measure depends on three factors: proper patient selection, adequate surgical technique, and safe cardiac prostheses. From 1986 until March 1990, 237 patients with stagnant heart failure were examined. Sixty-one patients (27%) were put on a waiting li...

journal_title：Artificial organs

authors： Shumakov V,Zimin N,Kazakov E,Kormer A,Vorontsov S,Nikolaenko E,Kozlov I,Drobyshev A

更新日期：1991-10-01 00:00:00

abstract：:In bioartificial pancreatic systems, isolated islets of Langerhans are protected against immune rejection by an artificial membrane, permeable to glucose and insulin, but not to immunoglobulins and lymphocytes. Some of these devices, referred to as vascular systems, are set up to be connected to a vascular site in the...

journal_title：Artificial organs

authors： Lepeintre J,Briandet H,Moussy F,Chicheportiche D,Darquy S,Rouchette J,Imbaud P,Duron JJ,Reach G

更新日期：1990-02-01 00:00:00

abstract：:In this study, we have developed an implantable electronics unit (IEU) for driving an undulation pump-left ventricular assist device (UP-LVAD). The IEU consists of a pump driver, three series-connected lithium ion batteries (1800 mAh), a charger, and a transcutaneous information transmission system. These electronic s...

journal_title：Artificial organs

authors： Okamoto E,Makino T,Inoue Y,Tanaka S,Yasuda T,Nakamura M,Saito I,Abe Y,Chinzei T,Isoyama T,Mochiizuki S,Imachi K,Mitamura Y

更新日期：2006-05-01 00:00:00

abstract：:Cardiomyoplasty has been proposed as an alternative surgical treatment for congestive heart failure. The girdling effect of the muscle wrap is believed to reduce diastolic wall stress. We tested the hypothesis that nonstimulated or passive cardiomyoplasty (CDM) would reduce hemodynamic deficits in rats with experiment...

journal_title：Artificial organs

authors： De Angelis K,Leirner AA,Irigoyen MC,Cestari IA

更新日期：2001-11-01 00:00:00

abstract：:To develop an effective hybrid bioartificial liver (BAL) device, the material of the scaffold is very important to support hepatocytes that have both growth ability and hepatic differentiated functions. In this study we used paper (Kimwipe, Kimberly-Clark Corp., Roswell, GA, U.S.A.) as a scaffold. Primary hepatocytes ...

journal_title：Artificial organs

authors： Mizuguchi T,Mitaka T,Sato F,Mochizuki Y,Hirata K

更新日期：2000-04-01 00:00:00

abstract：:A multi-compartment capillary membrane culture model with independently perfused three-dimensionally woven capillaries was developed for immobilization of hepatocytes in bioreactors. This enables spatial restructuring of cells and enhanced mass transfer performance with more efficient oxygenation and metabolite exchan...

journal_title：Artificial organs

authors： Gerlach J,Schnoy N,Smith MD,Neuhaus P

更新日期：1994-03-01 00:00:00

abstract：:To develop artificial materials for prolonged use in the vascular system, the complicated process of surface-induced thrombosis needs to be better understood. It is documented that certain antihypertensive drugs can inhibit platelet adhesion to an artificial surface; on the other hand, steroid drugs increase platelet ...

journal_title：Artificial organs

authors： Chandy T,Sharma CP

更新日期：1991-06-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB) is a nonphysiologic environment for an organism. The damage of blood components may also lead to organ dysfunction, some-times recognized as postperfusion syndrome. One possible way to diminish the risk of these complications would be to reduce the thorombogenicity and to improve the bioco...

journal_title：Artificial organs

authors： Horimoto H,Kondo K,Asada K,Sasaki S

更新日期：1996-08-01 00:00:00

abstract：:A compact three-dimensional (3D) module is needed for hepatocyte culture in order to develop an effective hybrid artificial liver system that can retain hepatocellular structure and differentiated functions. We treated the 3D module with collagen gel to entrap rat hepatocytes. This method yielded a high hepatocellular...

journal_title：Artificial organs

authors： Takeshita K,Ishibashi H,Suzuki M,Yamamoto T,Akaike T,Kodama M

更新日期：1995-02-01 00:00:00

abstract：:It is well known that the baroreflex system is one of the most important indicators of the pathophysiology in hypertensive patients. We can check the sensitivity of the baroreflex by observing heart rate (HR) responses; however, there is no simple diagnostic method to measure the arterial behavior in the baroreflex sy...

journal_title：Artificial organs

authors： Yambe T,Imachi K,Shiraishi Y,Yamaguchi T,Shibata M,Kameyama T,Yoshizawa M,Sugita N

更新日期：2009-09-01 00:00:00