Computational fluid dynamics and stent design.

Abstract:

:Stents are small, usually metallic tubes that are intended to prop open arteries blocked with atherosclerotic plaques. While stents have been used successfully in recent years, they still suffer from failure due to development of new tissue in stented segment (restenosis). Variations in the failure rates associated with different stent designs have led researchers to investigate the role of near-wall flow patterns. While there is no direct evidence yet, the patterns of flow stagnation as the blood flows past the stent struts may affect the restenosis process. Computational fluid dynamics (CFD) approaches are well suited for obtaining detailed information on stent flow patterns. Many CFD simulations make use of a two-dimensional model. The strong dependence of flow stagnation on stent strut spacing has been clearly demonstrated. These results have been employed to interpret the results of in vitro experiments designed to elucidate the mechanisms of restenosis.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Frank AO,Walsh PW,Moore JE Jr

doi

10.1046/j.1525-1594.2002.07084.x

subject

Has Abstract

pub_date

2002-07-01 00:00:00

pages

614-21

issue

7

eissn

0160-564X

issn

1525-1594

pii

aor7084

journal_volume

26

pub_type

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