High cell-density culture system of hepatocytes entrapped in a three-dimensional hollow fiber module with collagen gel.

abstract：:The aims of this study were to investigate whether introducing an interphase interval (IPI) to biphasic pulses during stimulation of the dorsiflexor muscles would affect force production and to determine whether the IPI effect is dependent on electrode position. Twelve healthy volunteers participated in the study. Eac...

journal_title：Artificial organs

authors： Springer S,Braun-Benyamin O,Abraham-Shitreet C,Becher M,Laufer Y

更新日期：2014-11-01 00:00:00

abstract：:Bubble blood oxygenators equipped with baffles of various types in the oxygenating column were studied. The rate of hemolysis, the volumetric coefficient for oxygen absorption into blood, and the fractional gas holdup were found to be affected mainly by the superficial gas velocity. When compared with the conventional...

journal_title：Artificial organs

authors： Ohshima N,Yoshido F

更新日期：1979-05-01 00:00:00

abstract：:A new intravascular pumping oxygenator (IVPO) was developed for intravascular gas exchange and circulatory assistance in critically ill patients with respiratory and circulatory failure. The IVPO utilizes new silicone hollow fibers (diameter, 1 mm; membrane width, 50 microns) and consists of two driving tubes for the ...

journal_title：Artificial organs

authors： Sueda T,Fukunaga S,Morita S,Sueshiro M,Hirai S,Okada K,Orihashi K,Matsuura Y

更新日期：1997-01-01 00:00:00

abstract：:The power-law based models for predicting shear-induced hemolysis are widely used in the optimization design of blood-contacting devices. However, this category of models has fallen short of accuracy when compared with the results of the in vitro experiments. The aim of this study is to develop an alternative model fr...

journal_title：Artificial organs

authors： Li H,Ruan X,Qian W,Fu X

更新日期：2014-12-01 00:00:00

abstract：:The growing practice of dialyzer reuse in recent years is mainly based on medical and economic considerations. However, adverse reactions such as immunohemolytic anemia due to anti-Nform antibody associated with dialyzer reuse have been reported. In this study, scanning electron microscopy and cytologic staining were ...

journal_title：Artificial organs

authors： Ng YY,Yang AH,Wong KC,Lan HY,Hung TL,Kerr PG,Huang TP

更新日期：1996-01-01 00:00:00

abstract：:Patients receiving mechanical circulatory support often present with heightened inflammation and free radical production associated with pre-existing conditions in addition to that which is due to blood interactions with nonbiological surfaces. The aim of this experimental laboratory study was to assess the deformabil...

journal_title：Artificial organs

authors： McNamee AP,Horobin JT,Tansley GD,Simmonds MJ

更新日期：2018-02-01 00:00:00

abstract：:The development of a ventricular assist device is depicted. The seven subprograms that make up the project are described briefly. Results obtained during the clinical assay showed that the new design of the input cannula working as a false auricle provides better efficiency, as well as a certain level of autoregulatio...

journal_title：Artificial organs

authors： del Cañizo JF,Antoranz JC,Desco MM,Alvarez-Valdivielso JM,Fernandez-Caleya D,López M,Garcia-Barreno P,Duarte J

更新日期：1994-07-01 00:00:00

abstract：:The thrombogenicity of membrane oxygenators as well as clotting parameters profiles, using standard human clotting tests, was analyzed in calves and pigs during 6 h perfusion. Three calves and 3 pigs were connected to extracorporeal circulation with standard heparinization. Blood samples were taken for coagulation var...

journal_title：Artificial organs

authors： Mueller XM,Tevaearai HT,Jegger D,Tucker O,von Segesser LK

更新日期：2001-07-01 00:00:00

abstract：:Myristoyl gelatin (MG) retains its gel structure at temperatures above body temperature without any crosslinking. As a coating material, MG adheres well to polyester fibers, and the outermost layers of the sealant that are in contact with blood or surrounding tissue become hydrophilic. We produced MG-impregnated knitt...

journal_title：Artificial organs

authors： Sasajima T,Inaba M,Azuma N,Goh K,Koshiko S,Kubo Y,Miyamoto K,Tokita M,Komai T

更新日期：1997-04-01 00:00:00

abstract：:The E4T is a totally implantable total artificial heart (TAH) resulting from many years of research work at the Cleveland Clinic Foundation (CCF) and Nimbus, Inc. It consists of four implanted subsystems: the pumping unit, the variable volume device, the transcutaneous transformer, and the internal battery. The pumpin...

journal_title：Artificial organs

authors： Smith WA,Hete BF,Kiraly RJ,Fujimoto LK,Jacobs GB,Ishikawa M,Butler K,Nosé Y

更新日期：1988-10-01 00:00:00

abstract：:Clinically, the percutaneous transcatheter aortic valve (TAV) has been reported to be deformed in a noncircular configuration after its implant. The deformation is universal and various, and it leads to serious leakage and durability problems. Even in the same deformation, the leaflets made in different tissue thickne...

journal_title：Artificial organs

authors： Feng W,Yang X,Liu Y,Fan Y

更新日期：2017-08-01 00:00:00

abstract：:The kinetic features of ultrafiltration of cellulose dialysis membrane stored under various humidity and temperature conditions were studied to obtain basic information of shelf-life characteristics of dialyzers. The ultrafiltration rate (UFR) decreased with time and the UFR-time curve suggested that the UFR would app...

journal_title：Artificial organs

authors： Sato H,Kidaka T

更新日期：1981-08-01 00:00:00

abstract：:Thrombosis and thromboembolism are the life-threatening clinical complications for patients supported or treated with prosthetic cardiovascular devices. The high mechanical shear stress within these devices is believed to be the major contributing factor to cause platelet activation (PA) and function alteration, leadi...

journal_title：Artificial organs

authors： Ding J,Chen Z,Niu S,Zhang J,Mondal NK,Griffith BP,Wu ZJ

更新日期：2015-07-01 00:00:00

abstract：:Options for mechanical circulatory support for the treatment of end-stage heart failure in children are limited. Ventricular assist devices (VADs), which have revolutionized cardiac care in adults, remain largely unavailable for pediatric applications. The PediPump is a new rotary dynamic VAD designed to provide suppo...

journal_title：Artificial organs

authors： Duncan BW,Lorenz M,Kopcak MW,Fukamachi K,Ootaki Y,Chen HM,Chapman PA,Davis SJ,Smith WA

更新日期：2005-07-01 00:00:00

abstract：:Biomechanical actuation of an implanted ventricular assist device (VAD) is an attractive means of providing long-term circulatory support. Studies show that energy from electrically stimulated skeletal muscle can, in principle, be used to provide tether-free cardiac assistance without the need for percutaneous driveli...

journal_title：Artificial organs

authors： Trumble DR

更新日期：2011-07-01 00:00:00

abstract：:This paper presents an overview of the U.S. Food and Drug Administration's regulatory requirements for introducing medical device and diagnostic products into commercial distribution in the United States. For any specific product, the requirements vary depending upon the product's associated risks, classification, and...

journal_title：Artificial organs

authors： Morton WA

更新日期：1982-11-01 00:00:00

abstract：:Electrolyzed water accelerated the healing of full-thickness cutaneous wounds in rats, but only anode chamber water (acid pH or neutralized) was effective. Hypochlorous acid (HOCl), also produced by electrolysis, was ineffective, suggesting that these types of electrolyzed water enhance wound healing by a mechanism un...

journal_title：Artificial organs

authors： Yahagi N,Kono M,Kitahara M,Ohmura A,Sumita O,Hashimoto T,Hori K,Ning-Juan C,Woodson P,Kubota S,Murakami A,Takamoto S

更新日期：2000-12-01 00:00:00

abstract：:This study deals with the design of a controller for cycling induced by functional electrical stimulation. The controller will be exploitable in the rehabilitation of hemiparetic patients who need to recover motor symmetry. It uses the pulse width as the control variable in the stimulation of the two legs in order to ...

journal_title：Artificial organs

authors： Ambrosini E,Ferrante S,Schauer T,Ferrigno G,Molteni F,Pedrocchi A

更新日期：2010-08-01 00:00:00

abstract：:Ten dialysis patients were followed in a prospective study to determine the neurotoxicity of metabolites in the middle molecule (MM) molecular weight (mol wt) range of 500-200 daltons/molecule. In the absence of readily available direct serum measurements of MM concentrations, a theoretically calculated dialysis index...

journal_title：Artificial organs

authors： Milutinovic J,Babb AL,Eschbach JW,Follette WC,Graefe U,Strand MJ,Scribner BH

更新日期：1978-02-01 00:00:00

abstract：:Loss of photoreceptor cells is one of the major causes of blindness. Several groups are exploring the functional replacement of photoreceptors by a retinal prosthesis. The goal of this study was to simulate the vision levels that recipients of retinal prostheses with 4 x 4, 6 x 10, and 16 x 16 electrode arrays may exp...

journal_title：Artificial organs

authors： Hayes JS,Yin VT,Piyathaisere D,Weiland JD,Humayun MS,Dagnelie G

更新日期：2003-11-01 00:00:00

abstract：:Late referral (LR) to dialysis therapy has been associated with poor outcomes in people with end-stage renal disease. This had been ascribed to the frequent use of temporary vascular catheters (TVCs) in LR patients. The effects of LR and TVC on the outcomes of an incident hemodialysis population (n = 101) were investi...

journal_title：Artificial organs

authors： Gonçalves EA,Andreoli MC,Watanabe R,Freitas MC,Pedrosa AC,Manfredi SR,Draibe SA,Cendoroglo M,Canziani ME

更新日期：2004-11-01 00:00:00

abstract：:Central extracorporeal life support (ECLS) is an effective treatment method of cardiogenic shock patients with or without lung failure. However, complications like infection and bleeding are common. The classical implantation approach requires full sternotomy, mobilization of the heart, with the well-known risks of bl...

journal_title：Artificial organs

authors： Weymann A,Sabashnikov A,Patil NP,Mohite PN,Zych B,Garcia Saez D,Popov AF,Simon AR

更新日期：2015-02-01 00:00:00

abstract：:In a typical open-heart surgery, the blood flow through the aortic cannula is a critical element of the cardiopulmonary bypass (CPB) procedure. Especially for the neonatal and pediatric CPB flow conditions, the need for small hydraulic diameter and large blood flow results confined turbulent jet flow regimes that exac...

journal_title：Artificial organs

authors： Rasooli R,Pekkan K

更新日期：2019-10-01 00:00:00

abstract：:To analyze the autonomic nervous system during left heart bypass with a vibrating flow pump (VFP), fluctuations in hemodynamic derivatives were evaluated by the spectral analysis method using fast fourier transform methodology. After the left pleural cavity was opened through the fourth intercostal space under general...

journal_title：Artificial organs

authors： Yambe T,Kobayashi S,Nanka S,Naganuma S,Nitta S,Matsuki H,Abe K,Yoshizawa M,Fukuju T,Tabayashi K,Takeda H,Hashimoto H

更新日期：1996-06-01 00:00:00

abstract：:The on-line measurement during hemodialysis of ionic dialysance provides an estimation of urea clearance with a good and already proven correlation. Some discrepancies remain controversial, and the influence of the dialyzer membrane is still being debated. Eighty-eight measurements of ionic dialysance (ID) were perfor...

journal_title：Artificial organs

authors： Mercadal L,Petitclerc T,Jaudon MC,Béné B,Goux N,Jacobs C

更新日期：1998-12-01 00:00:00

abstract：:We developed a new left ventricular (LV) assist catheter (transaortic valve from LV to femoral artery) that is implemented percutaneously and exerted as a synchronous pulsatile partial LV flow support with conventional intraaortic balloon pump (IABP) driving system and centrifugal pump system. We investigated whether ...

journal_title：Artificial organs

authors： Ide H,Yamaguchi A,Ino T,Matsumoto H,Fujimasa I

更新日期：1992-06-01 00:00:00

abstract：:The aim of this study was to evaluate the safety and performance of the Arrow CorAide left ventricular assist system (LVAS) (Arrow International, Reading, PA, USA), a continuous-flow left ventricular assist device, as bridge to transplantation or recovery as well as destination therapy in patients with New York Heart ...

journal_title：Artificial organs

authors： Saeed D,Arusoglu L,Gazzoli F,Hetzer R,Morshius M,Alloni A,Viganò M,Koerfer R,Golding LA,El Banayosy A

更新日期：2013-02-01 00:00:00

abstract：:The use of electrical stimulation for denervated muscles is still considered to be a controversial issue by many rehabilitation facilities and medical professionals because prior clinical experience has shown that treating denervated muscle tissue using exponential current over a long time period constitutes an imposs...

journal_title：Artificial organs

authors： Kern H,Hofer C,Strohhofer M,Mayr W,Richter W,Stöhr H

更新日期：1999-05-01 00:00:00

abstract：:Porous polyurethane (nonwoven) was used for the development of tracheal prosthesis, which--in a special testing design--was adapted to shape and biomechanic properties of the natural organ. This prosthesis was implanted into 19 beagle dogs using inverted, everted, and end-to-end anastomosis. Insufficiency of the anast...

journal_title：Artificial organs

authors： Schauwecker HH,Gerlach J,Planck H,Bücherl ES

更新日期：1989-06-01 00:00:00

abstract：:The microsystems based visual prosthesis (MiViP) visual prosthesis generates visual perceptions well below safety and stimulator saturation limits. These perceptions, called phosphenes, are of reasonably small size and are broadly distributed in the visual field. They can thus be used to convey useful visual informati...

journal_title：Artificial organs

authors： Delbeke J,Wanet-Defalque MC,Gérard B,Troosters M,Michaux G,Veraart C

更新日期：2002-03-01 00:00:00