Isoelastic polyurethane prosthesis for segmental trachea replacement in beagle dogs.


:Porous polyurethane (nonwoven) was used for the development of tracheal prosthesis, which--in a special testing design--was adapted to shape and biomechanic properties of the natural organ. This prosthesis was implanted into 19 beagle dogs using inverted, everted, and end-to-end anastomosis. Insufficiency of the anastomosis or infection was observed in the everted and end-to-end anastomosis, whereas the inverted anastomosis showed complete incorporation into surrounding tissue of the porous prosthesis but was complicated by airway obstruction due to anastomosis granuloma.


Artif Organs


Artificial organs


Schauwecker HH,Gerlach J,Planck H,Bücherl ES




Has Abstract


1989-06-01 00:00:00












  • The use of an approved biodegradable polymer scaffold as a solid support system for improvement of islet engraftment.

    abstract::The aim of this study was to investigate whether the use of a medically approved biodegradable scaffold as a solid support system would enhance graft survival following transplantation into the omental pouch in a preclinical large animal model. Six beagle dogs underwent total pancreatectomy followed by islet autotrans...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Kin T,O'Neil JJ,Pawlick R,Korbutt GS,Shapiro AM,Lakey JR

    更新日期:2008-12-01 00:00:00

  • Beta-2-microglobulin and main granulocyte components in hemodialysis patients.

    abstract::Plasma levels of granulocyte elastase in complex with alpha 1-proteinase inhibitor (E-alpha 1-PI) increased during hemodialysis from 110 +/- 10 to 506 +/- 66 micrograms/L using dialyzers made of polyamide, from 95 +/- 2.2 to 211 +/- 54 micrograms/ml with hemophane and from 114 +/- 10 to 203 +/- 25 using dialyzers made...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Haag-Weber M,Schollmeyer P,Hörl WH

    更新日期:1989-04-01 00:00:00

  • Development of a Tissue-Engineered Artificial Ligament: Reconstruction of Injured Rabbit Medial Collateral Ligament With Elastin-Collagen and Ligament Cell Composite Artificial Ligament.

    abstract::Ligament reconstruction using a tissue-engineered artificial ligament (TEAL) requires regeneration of the ligament-bone junction such that fixation devices such as screws and end buttons do not have to be used. The objective of this study was to develop a TEAL consisting of elastin-coated polydioxanone (PDS) sutures c...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Hirukawa M,Katayama S,Sato T,Inoue K,Niwa K,Ito N,Hattori T,Hosoi T,Unno H,Suzuki Y,Hasegawa M,Miyamoto K,Horiuchi T

    更新日期:2018-07-01 00:00:00

  • Ozone Prevents Cochlear Damage From Ischemia-Reperfusion Injury in Guinea Pigs.

    abstract::The cochlea is an end organ, which is metabolically dependent on a nutrient and oxygen supply to maintain its normal physiological function. Cochlear ischemia and reperfusion (IR) injury is considered one of the most important causes of human idiopathic sudden sensorineural hearing loss. The aim of the present study w...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Onal M,Elsurer C,Selimoglu N,Yilmaz M,Erdogan E,Bengi Celik J,Kal O,Onal O

    更新日期:2017-08-01 00:00:00

  • Re-endothelialization of non-detergent decellularized porcine vessels.

    abstract::Tissue engineering utilizes an interdisciplinary approach to generate constructs for the treatment and repair of diseased organs. Generation of small vessels as vascular grafts or as envisioned central vessel for vascularized constructs is still a challenge. Here, the decellularization of porcine vessels by a non-dete...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Eyre K,Samper E,Haverich A,Hilfiker A,Andrée B

    更新日期:2020-10-01 00:00:00

  • Prevention of right heart failure after left ventricular assist device implantation by phosphodiesterase 5 inhibitor.

    abstract::Right ventricular (RV) function immediately after left ventricular assist device (LVAD) implantation is a crucial prognostic factor. RV failure is linked to increased mortality and worse outcome. A phosphodiesterase 5 inhibitor, sildenafil, was shown to decrease pulmonary vascular resistance and pulmonary artery press...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Hamdan R,Mansour H,Nassar P,Saab M

    更新日期:2014-11-01 00:00:00

  • Improved mechanism for capturing muscle power for circulatory support.

    abstract::Although it is now understood that trained skeletal muscle can generate enough steady-state power to provide significant circulatory support, there are currently no means by which to tap this endogenous energy source to aid the failing heart. To that end, an implantable muscle energy converter (MEC) has been construct...

    journal_title:Artificial organs

    pub_type: 杂志文章,评审


    authors: Trumble DR,Melvin DB,Byrne MT,Magovern JA

    更新日期:2005-09-01 00:00:00

  • Effects of customized bicarbonate buffered solutions for continuous renal replacement therapies on polymorphonuclear leukocytes function and viability.

    abstract::It has previously been shown that the mixture of bicarbonate and calcium in the solutions used for continuous renal replacement therapy led to crystallization and significant changes in calcium concentration and pH. The aim of this study was to investigate the impact of bicarbonate/calcium and lactate/calcium solution...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Maccariello E,Dalboni MA,Draibe SA,Rocha E,Pavão dos Santos OF,Santos B,Cendoroglo M

    更新日期:2004-06-01 00:00:00

  • Analysis of left ventricular impedance in comparison with ultrasound images.

    abstract::Cardiac monitoring of ventricular assist devices (VADs) is important for detecting heart failure risks, such as critical arrhythmia and ventricular fibrillation, and for supplying data that are useful for hemodynamic control. Specifically, impedance cardiograms (ICGs) are especially beneficial because they have no eff...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Choi SW,Park SM

    更新日期:2012-05-01 00:00:00

  • Acquired Von Willebrand Syndrome and Blood Pump Design.

    abstract::The existence of acquired von Willebrand syndrome (AVWS) in patients with continuous flow left ventricular assist devices (LVADs) is well documented and has been verified by numerous investigators. AVWS has not been observed to occur in pulsatile devices such as the SynCardia total artificial heart (TAH), the HeartMat...

    journal_title:Artificial organs

    pub_type: 杂志文章,评审


    authors: Rosenberg G,Siedlecki CA,Jhun CS,Weiss WJ,Manning K,Deutsch S,Pierce W

    更新日期:2018-12-01 00:00:00

  • First experiences with outpatient care of patients with implanted axial flow pumps.

    abstract::As known from patients with pulsatile ventricular assist devices (VADs), early mobilization, physical exercise, and return to normal life are essential for optimal recovery. Recently, implantable rotary pumps became available for extended left ventricular support as bridges to transplantation. Modified procedures are ...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Wieselthaler GM,Schima H,Dworschak M,Quittan M,Nuhr M,Czerny M,Seebacher G,Huber L,Grimm M,Wolner E

    更新日期:2001-05-01 00:00:00

  • The accurate control of ultrafiltration.

    abstract::An apparatus has been contructed to regulate ultrafiltration accurately during dialysis. The principle of the apparatus is that, per unit of time, exactly the same amount of dialysate is introduced into the dialyzer as is discharged from it. The apparatus consists of two isovolumetric pumps connected in line. The four...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Flendrig JG,Carpay WM,Dekkers WT

    更新日期:1978-05-01 00:00:00

  • Single axis controlled hybrid magnetic bearing for left ventricular assist device: hybrid core and closed magnetic circuit.

    abstract::In previous studies, we presented main strategies for suspending the rotor of a mixed-flow type (centrifugal and axial) ventricular assist device (VAD), originally presented by the Institute Dante Pazzanese of Cardiology (IDPC), Brazil. Magnetic suspension is achieved by the use of a magnetic bearing architecture in w...

    journal_title:Artificial organs

    pub_type: 杂志文章,多中心研究


    authors: da Silva I,Horikawa O,Cardoso JR,Camargo FA,Andrade AJ,Bock EG

    更新日期:2011-05-01 00:00:00

  • The compliance problem: a major obstacle in the development of implantable blood pumps.

    abstract::The compliance problem represents a major obstacle in the development of implantable blood pumps. The motor-driven pumps are enclosed in an airtight casing with gas in the motor space. The trapped gas in the motor space either increases the load on the motor during systole or impedes blood sac filling. Potential solut...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Lee S,Rosenberg G,Donachy JH,Wisman CB,Pierce WS

    更新日期:1984-02-01 00:00:00

  • Extracorporeal life support during and after bilateral sequential lung transplantation in patients with pulmonary artery hypertension.

    abstract::The use of extracorporeal membrane oxygenator instead of standard cardiopulmonary bypass during lung transplantation is debatable. Moreover, recently, the concept of prolonged postoperative extracorporeal membrane oxygenator (ECMO) support has been introduced in many transplant centers to prevent primary graft dysfunc...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Dell'Amore A,Campisi A,Congiu S,Mazzarra S,Pastore S,Dolci G,Baiocchi M,Frascaroli G

    更新日期:2020-06-01 00:00:00

  • The PediPump: a new ventricular assist device for children.

    abstract::Options for mechanical circulatory support for the treatment of end-stage heart failure in children are limited. Ventricular assist devices (VADs), which have revolutionized cardiac care in adults, remain largely unavailable for pediatric applications. The PediPump is a new rotary dynamic VAD designed to provide suppo...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Duncan BW,Lorenz M,Kopcak MW,Fukamachi K,Ootaki Y,Chen HM,Chapman PA,Davis SJ,Smith WA

    更新日期:2005-07-01 00:00:00

  • Flow behavior within the 12-cc Penn State pulsatile pediatric ventricular assist device: an experimental study of the initial design.

    abstract::Planar particle image velocimetry was used to explore the flow behavior of the newly designed 12-cc Penn State pneumatic pediatric assist pump. Wall shear maps complemented the velocity data. Bjork-Shiley Monostrut 17-mm mechanical heart valves were used in the inlet and outlet ports. In comparison with larger Penn St...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Manning KB,Wivholm BD,Yang N,Fontaine AA,Deutsch S

    更新日期:2008-06-01 00:00:00

  • Nonsymmetric leaflet motion of St. Jude Medical mitral valves simulated with a computer-controlled hydraulic mock circulator.

    abstract::Since the introduction of high-performance prosthetic heart valves, particularly bileaflet valves and monoleaflet valves with larger opening angles, we have observed in vivo complex leaflet motion which has not been experimentally confirmed yet. We developed a computer-controlled hydraulic mock circulator to study the...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Ohta Y,Okamoto K,Sonderegger M,Dohi T,Matsumoto H,Horiuchi T

    更新日期:1997-04-01 00:00:00

  • Is Multiple Overlapping Uncovered Stents Technique Suitable for Aortic Aneurysm Repair?

    abstract::A computational fluid dynamic model to assess the impact of flow-diverter device on intra-aneurysmal flow in complex aortic aneurysm from the viewpoint of hemodynamics is presented. The aim of this study is to investigate the hemodynamic effects of an endovascular flow-diverter technique using multiple overlapping unc...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Yeow SL,Leo HL

    更新日期:2018-02-01 00:00:00

  • Modeling of a rotary blood pump.

    abstract::The accurate representation of rotary blood pumps in a numerical environment is important for meaningful investigation of pump-cardiovascular system interactions. Although numerous models for ventricular assist devices (VADs) have been developed, modeling methods for rotary total artificial hearts (rTAHs) are still re...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Nestler F,Bradley AP,Wilson SJ,Timms DL

    更新日期:2014-03-01 00:00:00

  • Survival of patients on chronic hemodialysis: single center experience.

    abstract::Patient survival from our hemodialysis (HD) center over the past 11 years was analyzed. Four hundred four patients, 212 female and 192 male, were treated by chronic intermittent HD. Patients were offered standard acetate-cellulosic membranes of 1.0-1.3 m2. During this period 181 patients died. One hundred three patien...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Polenakovik M,Sikole A,Stojcev N,Spasovski G,Amitov V,Nikolov V,Masin G,Klinkmann H

    更新日期:1999-01-01 00:00:00

  • Anticoagulation with fondaparinux for hemodiafiltration in patients with heparin-induced thrombocytopenia: dose-finding study and safety evaluation.

    abstract::The optimal anticoagulation regimen for hemodialysis (HD) in patients with heparin-induced thrombocytopenia (HIT) has not been defined. Hemodiafiltration (HDF) adds a large convective component to HD, thereby changing the pharmacokinetics of most anticoagulants. Data on coagulation regimens for HDF are scant. We there...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Mahieu E,Claes K,Jacquemin M,Evenepoel P,Op De Beek K,Bogaert AM,Kuypers D,Verhamme P,Meijers B

    更新日期:2013-05-01 00:00:00

  • Motor control in the human spinal cord.

    abstract::Features of the human spinal cord motor control are described using two spinal cord injury models: (i) the spinal cord completely separated from brain motor structures by accidental injury; (ii) the spinal cord receiving reduced and altered supraspinal input due to an incomplete lesion. Systematic studies using surfac...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Dimitrijevic MR,Persy I,Forstner C,Kern H,Dimitrijevic MM

    更新日期:2005-03-01 00:00:00

  • Optimal continuous retrograde coronary perfusion flow rate with beating heart in normal temperature.

    abstract:PURPOSE:We were led to the premise that with retrograde oxygenated blood perfusion, it would be possible to perform operations on the beating heart. METHODS:The experiment consisted of two stages: procedure 1 and 2. In procedure 1, six pigs were used. Retrograde perfusion flow was controlled to be in the range of 5.0-...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Tsukioka T,Tomita S,Watanabe G,Takemura H

    更新日期:2004-03-01 00:00:00

  • A new smartphone-based method for wound area measurement.

    abstract::Proper wound healing can be assessed by monitoring the wound surface area. Its reduction by 10 or 50% should be achieved after 1 or 4 weeks, respectively, from the start of the applied therapy. There are various methods of wound area measurement, which differ in terms of the cost of the devices and their accuracy. Thi...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Foltynski P,Ladyzynski P,Wojcicki JM

    更新日期:2014-04-01 00:00:00

  • Simple evaluation method of biocompatibility of artificial oxygenator hollow fiber.

    abstract::We made miniature modules filled with artificial oxygenator hollow fibers and conducted a simple experiment to study the effect of different membrane structures on the blood. Three types of modules were made: one filled with polyolefin, one filled with polypropylene, and a blank module. The 3 modules were connected th...

    journal_title:Artificial organs

    pub_type: 临床试验,杂志文章


    authors: Nishida H,Shibuya M,Endo M,Koyanagi H

    更新日期:1996-12-01 00:00:00

  • The impact of obesity on outcomes in patients receiving extracorporeal life support.

    abstract::Extracorporeal life support (ECLS) has been increasingly utilized to manage cardiac and pulmonary dysfunction. The impact of obesity on outcomes of ECLS is poorly defined. The purpose of the study was to compare in-hospital mortality, resource use, complications, and readmissions in obese versus non-obese patients rec...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Christian-Miller N,Hadaya J,Nakhla M,Sanaiha Y,Madrigal J,Emami S,Cale M,Sareh S,Benharash P

    更新日期:2020-11-01 00:00:00

  • Significance of percutaneous cardiopulmonary bypass support for volume reduction surgery with severe hypercapnia.

    abstract::In patients with reduced respiratory function, lung resection is associated with high risk because separate ventilation is generally needed for safe management. For patients with end-stage emphysema, intraoperative respiratory management is important and particularly difficult because neither incomplete oxygenation no...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Tsunezuka Y,Sato H,Tsubota M,Seki M

    更新日期:2000-01-01 00:00:00

  • Biodegradation and biocompatibility of polyorganophosphazene.

    abstract::We investigated biodegradation and biocompatibility of poly(organophosphazenes). We prepared poly(organophosphazenes) having different side chain groups. The blood compatibility of poly(organophosphazenes) containing fluorinated side groups, poly(bis[trifluoroethoxy]phosphazene) (PbFP) and poly([trifluoroethoxy][ethyl...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Kawakami H,Kanezaki S,Sudo M,Kanno M,Nagaoka S,Kubota S

    更新日期:2002-10-01 00:00:00

  • Termination of extracorporeal membrane oxygenation for cardiac support.

    abstract::The determination of when to stop extracorporeal membrane oxygenation (ECMO) rests upon demonstration of the return of adequate cardiac function to support vital organs and permit subsequent recovery. In general, patients with myocardial stun will recover function within several days. Factors that limit recovery inclu...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Steinhorn DM

    更新日期:1999-11-01 00:00:00