Isoelastic polyurethane prosthesis for segmental trachea replacement in beagle dogs.


:Porous polyurethane (nonwoven) was used for the development of tracheal prosthesis, which--in a special testing design--was adapted to shape and biomechanic properties of the natural organ. This prosthesis was implanted into 19 beagle dogs using inverted, everted, and end-to-end anastomosis. Insufficiency of the anastomosis or infection was observed in the everted and end-to-end anastomosis, whereas the inverted anastomosis showed complete incorporation into surrounding tissue of the porous prosthesis but was complicated by airway obstruction due to anastomosis granuloma.


Artif Organs


Artificial organs


Schauwecker HH,Gerlach J,Planck H,Bücherl ES




Has Abstract


1989-06-01 00:00:00












  • Unsteady fluid dynamics of several mechanical prosthetic heart valves using a two component laser Doppler anemometer system.

    abstract::Five typical mechanical heart valves (Starr-Edwards, Björk-Shiley convexo-concave (c-c), Björk-Shiley monostrut, Bicer-Val, and St. Jude Medical) were tested in the mitral position under the pulsatile flow condition. The test program included measurements of velocity and turbulent stresses at 5 downstream locations. T...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Akutsu T,Modi VJ

    更新日期:1997-10-01 00:00:00

  • Development and clinical assay of the BCM ventricular assist device.

    abstract::The development of a ventricular assist device is depicted. The seven subprograms that make up the project are described briefly. Results obtained during the clinical assay showed that the new design of the input cannula working as a false auricle provides better efficiency, as well as a certain level of autoregulatio...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: del Cañizo JF,Antoranz JC,Desco MM,Alvarez-Valdivielso JM,Fernandez-Caleya D,López M,Garcia-Barreno P,Duarte J

    更新日期:1994-07-01 00:00:00

  • Improved mechanism for capturing muscle power for circulatory support.

    abstract::Although it is now understood that trained skeletal muscle can generate enough steady-state power to provide significant circulatory support, there are currently no means by which to tap this endogenous energy source to aid the failing heart. To that end, an implantable muscle energy converter (MEC) has been construct...

    journal_title:Artificial organs

    pub_type: 杂志文章,评审


    authors: Trumble DR,Melvin DB,Byrne MT,Magovern JA

    更新日期:2005-09-01 00:00:00

  • Is the dog a useful model for accelerated calcification study of cardiovascular bioprostheses?

    abstract::Chitosan posttreatment has been shown to be effective in prevention of calcification of the glutaraldehyde treated bovine pericardium when implanted subdermally in rats for 12 weeks. The efficacy of chitosan posttreatment in complete calcium mitigation of the glutaraldehyde treated porcine aortic valves implanted in t...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Chanda J,Kuribayashi R,Abe T,Sekine S,Shibata Y,Yamagishi I

    更新日期:1997-05-01 00:00:00

  • The effects of homologous cross-circulation and in situ liver perfusion on fulminant hepatic failure rats.

    abstract::A galactosamine-induced fulminant hepatic failure (FHF) rat model was used to study the effects of homologous cross-circulation and in situ liver perfusion. Cross-circulation with homologous donors did not significantly improve the survival time or recovery rate of grade II hepatic coma rats. Homologous in situ liver ...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Mohsini K,Lister C,Chang TM

    更新日期:1980-08-01 00:00:00

  • Bioengineered cartilage in a scaffold-free method by human cartilage-derived progenitor cells: a comparison with human adipose-derived mesenchymal stromal cells.

    abstract::The objective of our study was to investigate chondrogenesis potential of human adipose-derived mesenchymal stromal cells (MSCs), using as a positive control a human source of cartilage-derived progenitor cells (PCs). This source of PCs was recently described by our group and dwells on the surface of nasoseptal cartil...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Baptista LS,Silva KR,Pedrosa CS,Amaral RJ,Belizário JV,Borojevic R,Granjeiro JM

    更新日期:2013-12-01 00:00:00

  • The need for standardizing the index of hemolysis.

    abstract::Hemolysis is one of the most important performance parameters of blood pumps. However, comparative in vitro evaluation of the reported hemolysis effect is difficult owing to the lack of uniformity in the test methods used. Currently, three types of formulas are generally accepted and widely used for the index of hemol...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Naito K,Mizuguchi K,Nosé Y

    更新日期:1994-01-01 00:00:00

  • Liposome-encapsulated hemoglobin alleviates brain edema after permanent occlusion of the middle cerebral artery in rats.

    abstract::Liposome-encapsulated hemoglobin (LEH) was proven to be protective in cerebral ischemia/reperfusion injury. The present study evaluated LEH in a rat model of permanent middle cerebral artery (MCA) occlusion to clarify its effect during ischemia and reperfusion. Five minutes after thread occlusion of the MCA, rats were...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Kawaguchi AT,Kurita D,Furuya H,Yamano M,Ogata Y,Haida M

    更新日期:2009-02-01 00:00:00

  • Intravascular micropump for augmented liver perfusion: first in vivo experience.

    abstract::The aim of this study was to assess the in vivo performance of a new microaxial rotary blood pump developed for long-term intraportal implantation. The pump, measuring 7 mm in diameter, has a single stage impeller and is powered by a microelectric motor. The pump was implanted into the portal vein in 13 large white pi...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Havlík R,Kerkhoffs W,Jiao LR,Schumacher O,Reul H,Habib N

    更新日期:2001-05-01 00:00:00

  • Feasibility of extracorporeal on-line large-scale plasma adsorptions on protein A-sepharose columns in cancer patients.

    abstract::The feasibility of extracorporeal adsorption of 1.5-3 L plasma on protein A-Sepharose was investigated in six patients with advanced cancer. Anticoagulation with heparin was associated with respiratory distress syndrome in two patients, most likely caused by complement activation as indicated by a transient leukopenia...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Wallmark A,Grubb A,Freiburghaus C,Flodgren P,Husberg B,Lindholm T,Lindström C,Thysell H,Sjögren HO

    更新日期:1984-02-01 00:00:00

  • Flow visualization study on centrifugal blood pump using a high speed video camera.

    abstract::Flow visualization is widely applied to evaluate rotary blood pumps; however, it is very difficult to visualize flow near the vanes of centrifugal blood pumps because the rotational speed of the impeller is usually several thousand rpm. In this study, a tracer method with a high speed video camera that can take more t...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Sakuma I,Tadokoro H,Fukui Y,Dohi T

    更新日期:1995-07-01 00:00:00

  • Development of integrated electronics unit for drive and control of undulation pump-left ventricular assist device.

    abstract::In this study, we have developed an implantable electronics unit (IEU) for driving an undulation pump-left ventricular assist device (UP-LVAD). The IEU consists of a pump driver, three series-connected lithium ion batteries (1800 mAh), a charger, and a transcutaneous information transmission system. These electronic s...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Okamoto E,Makino T,Inoue Y,Tanaka S,Yasuda T,Nakamura M,Saito I,Abe Y,Chinzei T,Isoyama T,Mochiizuki S,Imachi K,Mitamura Y

    更新日期:2006-05-01 00:00:00

  • A compact mock circulation loop for the in vitro testing of cardiovascular devices.

    abstract::In vitro cardiovascular device performance evaluation in a mock circulation loop (MCL) is a necessary step prior to in vivo testing. A MCL that accurately represents the physiology of the cardiovascular system accelerates the assessment of the device's ability to treat pathological conditions. To serve this purpose, a...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Timms DL,Gregory SD,Greatrex NA,Pearcy MJ,Fraser JF,Steinseifer U

    更新日期:2011-04-01 00:00:00

  • Coronary artery anatomy of the goat.

    abstract::The coronary arteries of the goat heart were studied using angiographic techniques and molds of the coronary vessel trees. Blood supplies to the left and right ventricles, interventricular septum, atrioventricular node, and apex of the caprine heart were studied. The goat possesses a left dominant pattern of coronary ...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Lipovetsky G,Fenoglio JJ,Gieger M,Srinivasan MR,Dobelle WH

    更新日期:1983-05-01 00:00:00

  • Paracorporeal artificial heart in postoperative heart failure.

    abstract::A pneumatically driven artificial heart with a tubular silicone rubber membrane and disc valves was used for functional heart replacement in the paracorporeal mode. A fluidic drive system allows adjustment of the heart rate, positive and negative pressures and systole/diastole ratio. Since August, 1977, the artificial...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Turina MT,Bosio R,Senning A

    更新日期:1978-08-01 00:00:00

  • An advanced mock circulation loop for in vitro cardiovascular device evaluation.

    abstract::Controlled and repeatable in vitro evaluation of cardiovascular devices using a mock circulation loop (MCL) is essential prior to in vivo or clinical trials. MCLs often consist of only a systemic circulation with no autoregulatory responses and limited validation. This study aimed to develop, and validate against huma...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Gregory SD,Pauls JP,Wu EL,Stephens A,Steinseifer U,Tansley G,Fraser JF

    更新日期:2020-06-01 00:00:00

  • Evaluation of membrane oxygenators and reservoirs in terms of capturing gaseous microemboli and pressure drops.

    abstract::An increasing amount of evidence points to cerebral embolization during cardiopulmonary bypass (CPB) as the principal etiologic factor of neurologic complications. In this study, the capability of capturing and classification of gaseous emboli and pressure drop of three different membrane oxygenators (Sorin Apex, Teru...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Guan Y,Palanzo D,Kunselman A,Undar A

    更新日期:2009-11-01 00:00:00

  • Intravenous prostacyclin mitigates inhaled nitric oxide rebound effect: A case control study.

    abstract::Although extracorporeal membrane oxygenation (ECMO) improves oxygenation, pulmonary vascular resistance may be increased due to endothelial function impairment. Inhaled nitric oxide (iNO) is increasingly used for treatment of pulmonary hypertension after surgical repair of congenital heart defects, with or without ECM...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Hermon M,Golej J,Burda G,Marx M,Trittenwein G,Pollak A

    更新日期:1999-11-01 00:00:00

  • Experimental setup to evaluate the performance of percutaneous pulmonary valved stent in different outflow tract morphologies.

    abstract::Percutaneous pulmonary valve implantation is a potential treatment for right ventricular outflow tract (RVOT) dysfunction. However, RVOT implantation site varies among subjects and the success of the procedure depends on RVOT morphology selection. The aim of this study was to use in vitro testing to establish percutan...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Vismara R,Laganà K,Migliavacca F,Schievano S,Coats L,Taylor A,Bonhoeffer P

    更新日期:2009-01-01 00:00:00

  • Anionic collagen: polymer composites with improved dielectric and rheological properties.

    abstract::This work describes the preparation and characterization of anionic collagen composites with rhamsan and vinylidene fluoride-trifluorethylene with improved rheological and dielectric properties without loss of collagen secondary structure with an interaction occurring between both macromolecules of the composites. On ...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Goissis G,Piccirili L,Goes JC,de Guzzi Plepis AM,Das-Gupta DK

    更新日期:1998-03-01 00:00:00

  • Behavior of endothelial cells cultured on Silastic and Dacron velour under flow conditions in vitro: implications for prelining vascular grafts with cells.

    abstract::Tissue-cultured bovine aortic endothelial cells were subjected to flow in an in vitro circulatory loop designed to simulate the flow and pressure conditions in the aorta. The cells were cultured under stationary conditions on tubes of fibronectin-coated Silastic or of Dacron velour. The tubes were then added to the fl...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Eskin SG,Navarro LT,O'Bannon W,DeBakey ME

    更新日期:1983-02-01 00:00:00

  • Effects of pyridoxalated hemoglobin polyoxyethylene conjugate and other hemoglobin-related substances on arterial blood pressure in anesthetized and conscious rats.

    abstract::The effects of pyridoxalated hemoglobin polyoxyethylene conjugate (PHP) and other hemoglobin-related substances on arterial blood pressure (ABP) and heart rate (HR) were examined. Infusion of PHP and other hemoglobin-related substances elevated ABP and increased HR. The degree of the increase in ABP and HR did not dif...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Kida Y,Maeda M,Iwata S,Iwashita Y,Goto K,Nishi K

    更新日期:1995-02-01 00:00:00

  • Central Extracorporeal Life Support With Left Ventricular Decompression to Berlin Heart Excor: A Reliable "Bridge to Bridge" Strategy in Crash and Burn Patients.

    abstract::The aim of this study was to compare patients with severe biventricular heart failure who underwent Berlin Heart Excor implantation with (cardiogenic shock [CS] status) or without the need for preoperative extracorporeal life support (ECLS) as a bridge to long-term device. A total of 40 consecutive patients with sever...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Weymann A,Farag M,Sabashnikov A,Fatullayev J,Zeriouh M,Schmack B,Arif R,Müller F,Alt C,Raake P,Prakash Patil N,Popov AF,Rüdiger Simon A,Karck M,Ruhparwar A,Heidelberg-Cologne-Harefield Cardiothoracic Transplantation & Mecha

    更新日期:2017-06-01 00:00:00

  • Surface modification of silicone rubber membrane by plasma induced graft copolymerization as artificial cornea.

    abstract::In this study a highly biocompatible polymer membrane was prepared by surface modification. An artificial cornea was also developed for clinical applications. Silicone rubber (SR) membrane was grafted with hydrophilic monomers such as 2-hydroxyethyl methacrylate (HEMA) and acrylic acid by plasma induced grafted polyme...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Hsiue GH,Lee SD,Chang PC

    更新日期:1996-11-01 00:00:00

  • Is the New Infant Jarvik 2015 Suitable for Patients

    abstract::Our aim was to study the feasibility of implanting the Infant Jarvik 2015 in patients weighing less than 8 kg. The Infant Jarvik 2015 left ventricular assist device (LVAD) was tested in a hybrid simulator of the cardiovascular system reproducing specific patients' hemodynamics for different patient weights (2-7 kg). F...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Di Molfetta A,Zielinski K,Ferrari G,Kozarski M,Okrzeja P,Iacobelli R,Filippelli S,Perri G,Darowski M,Massetti M,Jarvik R,Amodeo A

    更新日期:2019-01-01 00:00:00

  • Technical aspects on middle molecules: separation, isolation, and identification.

    abstract::For the last few years we have attempted to separate and isolate from biological fluids the uremic Middle Molecules (MM). The first step in the treatment of plasma is an ultrafiltration through AN69 membrane. The samples are fractionated by Sephadex G-15 chromatography into 9 peaks "a" to "i' under precise conditions ...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Cueille G,Man NK,Sausse A,Farges JP,Funck-Brentano JL

    更新日期:1981-01-01 00:00:00

  • Computational fluid dynamics and stent design.

    abstract::Stents are small, usually metallic tubes that are intended to prop open arteries blocked with atherosclerotic plaques. While stents have been used successfully in recent years, they still suffer from failure due to development of new tissue in stented segment (restenosis). Variations in the failure rates associated wi...

    journal_title:Artificial organs

    pub_type: 杂志文章,评审


    authors: Frank AO,Walsh PW,Moore JE Jr

    更新日期:2002-07-01 00:00:00

  • Constraint stress, microstructural characteristics, and enhanced mechanical properties of a special fibroblast-embedded collagen construct.

    abstract::Cell-contracted collagen gels could provide rejection-free biomaterials for tissue engineering, but their application is limited by relatively low mechanical strength. We developed a special type I collagen construct (based on embedded fibroblasts) that was formed into a gel thread by using two anchors to constrain ge...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Feng Z,Ishibashi M,Nomura Y,Kitajima T,Nakamura T

    更新日期:2006-11-01 00:00:00

  • An image processing approach for blind mobility facilitated through visual intracortical stimulation.

    abstract::This article presents an image processing approach dedicated for a blind mobility aid facilitated through visual intracortical electrical stimulation. The method examines a display framework based on the distances related to a scene. The distances of objects to the walker are measured using a size perspective method w...

    journal_title:Artificial organs

    pub_type: 杂志文章


    authors: Mohammadi HM,Ghafar-Zadeh E,Sawan M

    更新日期:2012-07-01 00:00:00

  • Electrochemical and Electrophysiological Performance of Platinum Electrodes Within the Ninety-Nine-Electrode Stimulating Nerve Cuff.

    abstract::The trend in neural prostheses using selective nerve stimulation for electrical stimulation therapies is headed toward single-part systems having a large number of working electrodes (WEs), each of which selectively stimulate neural tissue or record neural response (NR). The present article reviews the electrochemical...

    journal_title:Artificial organs

    pub_type: 杂志文章,评审


    authors: Pečlin P,Mehle A,Karpe B,Rozman J

    更新日期:2015-10-01 00:00:00