A hybrid mock circulation loop for a total artificial heart.

abstract：:In this study, we investigated the differences between pulsatile cardiopulmonary bypass (CPB) procedure and nonpulsatile CPB procedure in terms of their effects on hemolysis and deformability of red blood cells (RBCs) under various shear stress conditions. In order to research the effects on hemolysis and deformabilit...

journal_title：Artificial organs

authors： Kang YJ,Kim MG,Son KH,Lim CH,Son HS,Yoon SY,Kwon HS,Yang S

更新日期：2010-04-01 00:00:00

abstract：:The aim of this study was to assess the in vivo performance of a new microaxial rotary blood pump developed for long-term intraportal implantation. The pump, measuring 7 mm in diameter, has a single stage impeller and is powered by a microelectric motor. The pump was implanted into the portal vein in 13 large white pi...

journal_title：Artificial organs

authors： Havlík R,Kerkhoffs W,Jiao LR,Schumacher O,Reul H,Habib N

更新日期：2001-05-01 00:00:00

abstract：:The objective of our study was to investigate chondrogenesis potential of human adipose-derived mesenchymal stromal cells (MSCs), using as a positive control a human source of cartilage-derived progenitor cells (PCs). This source of PCs was recently described by our group and dwells on the surface of nasoseptal cartil...

journal_title：Artificial organs

authors： Baptista LS,Silva KR,Pedrosa CS,Amaral RJ,Belizário JV,Borojevic R,Granjeiro JM

更新日期：2013-12-01 00:00:00

abstract：:We aimed to determine the effect of elective left heart decompression at the time of initiation of central venoarterial extracorporeal membrane oxygenation (VA ECMO) on VA ECMO duration and clinical outcomes in children in a single tertiary ECMO referral center with a large pediatric population from a national referra...

journal_title：Artificial organs

authors： Hacking DF,Best D,d'Udekem Y,Brizard CP,Konstantinov IE,Millar J,Butt W

更新日期：2015-04-01 00:00:00

abstract：:In this study a highly biocompatible polymer membrane was prepared by surface modification. An artificial cornea was also developed for clinical applications. Silicone rubber (SR) membrane was grafted with hydrophilic monomers such as 2-hydroxyethyl methacrylate (HEMA) and acrylic acid by plasma induced grafted polyme...

journal_title：Artificial organs

authors： Hsiue GH,Lee SD,Chang PC

更新日期：1996-11-01 00:00:00

abstract：:We have studied the cardiac beat synchronization (CBS) control for a rotary blood pump (RBP) and revealed that it can promote pulsatility and reduce cardiac load. Besides, patients with LVAD support sometimes suffer from aortic and mitral regurgitation (AR and MR). A control method for the RBP should be validated in w...

journal_title：Artificial organs

authors： Ogawa D,Kobayashi S,Yamazaki K,Motomura T,Nishimura T,Shimamura J,Tsukiya T,Mizuno T,Takewa Y,Tatsumi E,Nishinaka T

更新日期：2020-08-19 00:00:00

abstract：:Small blood vessels may play a more important role in artificial heart (AH) recipients than ever suspected before. Observations of elevated total peripheral resistance, low hematocrit, reduced oncotic pressure, high circulating blood volume, and arterial pulsations with nonpulsatile devices require consideration of pe...

journal_title：Artificial organs

authors： Lübbe AS

更新日期：1988-02-01 00:00:00

abstract：:In chronic cardiomyopathy, mechanical circulatory support (MCS) plays an increasingly important role for children as the shortage of suitable donor hearts increases waiting time on the transplant list. We report our experience with the paracorporal Berlin Heart EXCOR System (Berlin Heart AG, Berlin, Germany) used as a...

journal_title：Artificial organs

authors： Schweiger M,Schrempf J,Sereinigg M,Prenner G,Tscheliessnigg KH,Wasler A,Krumnikel J,Gamillschegg A,Knez I

更新日期：2013-08-01 00:00:00

abstract：:This study deals with the design of a controller for cycling induced by functional electrical stimulation. The controller will be exploitable in the rehabilitation of hemiparetic patients who need to recover motor symmetry. It uses the pulse width as the control variable in the stimulation of the two legs in order to ...

journal_title：Artificial organs

authors： Ambrosini E,Ferrante S,Schauer T,Ferrigno G,Molteni F,Pedrocchi A

更新日期：2010-08-01 00:00:00

abstract：:Patients receiving mechanical circulatory support often present with heightened inflammation and free radical production associated with pre-existing conditions in addition to that which is due to blood interactions with nonbiological surfaces. The aim of this experimental laboratory study was to assess the deformabil...

journal_title：Artificial organs

authors： McNamee AP,Horobin JT,Tansley GD,Simmonds MJ

更新日期：2018-02-01 00:00:00

abstract：:In 1993, the development began of a small axial flow blood pump, the DeBakey ventricular assist device (VAD). The material was recently converted to a titanium alloy, and a waterproof pump package was incorporated for long-term intracorporeal circulation. Thirteen intrathoracic implantations in calves were achieved. N...

journal_title：Artificial organs

authors： Tayama E,Olsen DB,Ohashi Y,Benkowski R,Morley D,Noon GP,Nosé Y,Debakey ME

更新日期：1999-12-01 00:00:00

abstract：:A belt worn controller and lithium-ion battery pack have been developed for use with the initial clinical trials of the Jarvik 2000 heart. Patient interface considerations, safety, and simplicity were major design inputs for the system. The controller was developed using all analog technology to avoid difficulties wit...

journal_title：Artificial organs

authors： Jarvik R,Scott V,Morrow M,Takecuhi E

更新日期：1999-06-01 00:00:00

abstract：:The Symbion Acute Ventricular Assist Device (AVAD) System is an experimental paracorporeal pulsatile ventricular assist device (VAD) for single or biventricular assist. Eleven patients were implanted but 2 died within 24 h and were excluded from the study. Nine patients, four with left ventricular assist devices (LVAD...

journal_title：Artificial organs

authors： Icenogle TB,Smith RG,Cleavinger M,Vasu MA,Williams RJ,Sethi GK,Copeland JG

更新日期：1989-12-01 00:00:00

abstract：:A woven fabric graft made of ultrafine polyester fibers (UFPF) (Toray Graft, water porosity: 100 ml/min/cm2:120 mm Hg H2O) was clinically applied in 81 cases (28 thoracic aortic aneurysms, 6 thoracoabdominal aortic aneurysms, 42 abdominal aortic aneurysms, and 5 atherosclerotic obstructions of the peripheral arteries)...

journal_title：Artificial organs

authors： Satoh S,Niu S,Kanda K,Hirai J,Nakazima S,Wada Y,Oka T,Noishiki Y

更新日期：1995-01-01 00:00:00

abstract：:Over the last 5 years, 12 patients received ventricular assist devices (VADs) while in postcardiotomy cardiogenic shock. There were 7 male and 5 female patients ranging in age from 22 to 73 years (average age, 54). Eight patients underwent surgery for valve replacements, 3 for coronary artery bypass graftings, and 1 f...

journal_title：Artificial organs

authors： Murakami T,Nakayama H,Irie H,Kino K,Hisamochi K,Koomoto T,Takagaki M,Sugawara E,Senoo Y,Teramoto S

更新日期：1993-07-01 00:00:00

abstract：:In a calf model, 3 standard and 3 heparin coated intraaortic balloons (IAB) were inserted and left deflated in the descending aorta during 20 min to simulate balloon rupture. At the end of the experiment, the IAB were examined, and 3 samples of each were collected for scanning electron microscopy (SEM) analysis. None ...

journal_title：Artificial organs

authors： Mueller XM,Tevaearai HT,Hayoz D,von Segesser LK

更新日期：1999-02-01 00:00:00

abstract：:Malnutrition is a common feature seen in chronic dialysis patients, and the survival rate of obese patients receiving such treatment is higher than that of lean patients. Irrespective of obesity or diabetes, dialysis patients commonly have insulin resistance, and the leading cause of death is cardiovascular (CV) disea...

journal_title：Artificial organs

authors： Tanaka S,Yano S,Sheikh AM,Nagai A,Sugimoto T

更新日期：2014-07-01 00:00:00

abstract：:The compliance problem represents a major obstacle in the development of implantable blood pumps. The motor-driven pumps are enclosed in an airtight casing with gas in the motor space. The trapped gas in the motor space either increases the load on the motor during systole or impedes blood sac filling. Potential solut...

journal_title：Artificial organs

authors： Lee S,Rosenberg G,Donachy JH,Wisman CB,Pierce WS

更新日期：1984-02-01 00:00:00

abstract：:Centrifugal pumps are generally employed as nonpulsatile blood flow pumps; however, these pumps can produce pulsatile flow by periodically alternating the impeller rotation speed. This study investigates blood trauma due to the effect of pulse frequency and various ranges of pump speed. The hemolysis tests were conduc...

journal_title：Artificial organs

authors： Tayama E,Niimi Y,Takami Y,Ohashi Y,Ohtsuka G,Glueck JA,Mueller J,Nosé Y

更新日期：1997-12-01 00:00:00

abstract：:Extracorporeal human lymphatic organs are expected to be excellent tools in the study of human molecular and cellular bases of the immunologic balance and tissue harmony. A rational approach and process to design a device and a procedure to recreate the human lymph node environment in vitro is described with emphasis ...

journal_title：Artificial organs

authors： Giese C,Demmler CD,Ammer R,Hartmann S,Lubitz A,Miller L,Müller R,Marx U

更新日期：2006-10-01 00:00:00

abstract：:Spiral/helical forms of blood flow have been observed in large arteries of the cardiovascular system, but their benefits remain underappreciated. Spiral flow has been postulated to improve near-wall washout, promoting anti-atherothrombotic conditions. This research aims to study the washout characteristics of spiral f...

journal_title：Artificial organs

authors： Huang Zhang P,Tkatch C,Newman R,Grimme W,Vainchtein D,Kresh JY

更新日期：2019-12-01 00:00:00

abstract：:Renal Solutions Allient Sorbent Hemodialysis System utilizes a two-chambered pneumatic pump (Pulsar Blood Pump, Renal Solutions, Inc., Warrendale, PA, USA) to avoid limitations associated with peristaltic pumping systems. Single-needle access is enabled by counter-pulsing the two pump chambers, thereby obviating compl...

journal_title：Artificial organs

authors： Shu F,Parks R,Maholtz J,Ash S,Antaki JF

更新日期：2009-04-01 00:00:00

abstract：:The specific timing for discontinuing renal replacement therapy (RRT) in acute kidney injury (AKI) patients is debatable. The predictive abilities of variables at the time of discontinuation of RRT for the long-term prognoses of patients have not been explored. This study aimed to explore the prognostic factors upon d...

journal_title：Artificial organs

authors： Yang T,Sun S,Lin L,Han M,Liu Q,Zeng X,Zhao Y,Li Y,Su B,Huang S,Yang L

更新日期：2017-12-01 00:00:00

abstract：:Plasma levels of granulocyte elastase in complex with alpha 1-proteinase inhibitor (E-alpha 1-PI) increased during hemodialysis from 110 +/- 10 to 506 +/- 66 micrograms/L using dialyzers made of polyamide, from 95 +/- 2.2 to 211 +/- 54 micrograms/ml with hemophane and from 114 +/- 10 to 203 +/- 25 using dialyzers made...

journal_title：Artificial organs

authors： Haag-Weber M,Schollmeyer P,Hörl WH

更新日期：1989-04-01 00:00:00

abstract：:Pharmacologic agents and other non-protein-bound compounds smaller than 5,000 daltons have the potential to be removed by continuous arteriovenous hemofiltration (CAVH). A proposed method for estimating drug clearance by CAVH (ClCAVH) equates ultrafiltrate clearance to the product of the sieving coefficient and the av...

journal_title：Artificial organs

authors： Horton MW,Godley PJ,Moore ES,Fineg J,Gillespie WR

更新日期：1990-12-01 00:00:00

abstract：:To overcome the weak mechanical properties of cell/hydrogel composites, a poly(DL-lactic-co-glycolic acid) sandwiched adipose-derived stem cell (ADSC)/fibrin construct was fabricated using a step-by-step mold/extraction method to generate the middle smooth muscle layer of natural blood vessels. A pulse bioreactor with...

journal_title：Artificial organs

authors： Wang X,Sui S

更新日期：2011-06-01 00:00:00

abstract：:The thrombogenicity of membrane oxygenators as well as clotting parameters profiles, using standard human clotting tests, was analyzed in calves and pigs during 6 h perfusion. Three calves and 3 pigs were connected to extracorporeal circulation with standard heparinization. Blood samples were taken for coagulation var...

journal_title：Artificial organs

authors： Mueller XM,Tevaearai HT,Jegger D,Tucker O,von Segesser LK

更新日期：2001-07-01 00:00:00

abstract：:To provide percutaneous access, a new circulatory assist system was developed. We call this newly developed system the modified assist device (MAD). The system is composed of a sac-type blood pump and cannula. Inflow and outflow valves are mounted in the apex and at the side wall 10 cm from the apex of the cannula, re...

journal_title：Artificial organs

authors： Imanishi K,Imachi K,Yoshito H,Isoyama T,Abe Y,Chinzei T,Mabuchi K,Kanda K,Tsutsui N,Suma K,Fujimasa I

更新日期：1996-02-01 00:00:00

abstract：:Patient survival from our hemodialysis (HD) center over the past 11 years was analyzed. Four hundred four patients, 212 female and 192 male, were treated by chronic intermittent HD. Patients were offered standard acetate-cellulosic membranes of 1.0-1.3 m2. During this period 181 patients died. One hundred three patien...

journal_title：Artificial organs

authors： Polenakovik M,Sikole A,Stojcev N,Spasovski G,Amitov V,Nikolov V,Masin G,Klinkmann H

更新日期：1999-01-01 00:00:00

abstract：:Hemodynamic control of left ventricular assist devices (LVADs) is generally a complicated problem due to diverse operating environments and the variability of the patients: both the changes in the circulatory and metabolic parameters as well as disturbances that require adjustment to the operating point. This challeng...

journal_title：Artificial organs

authors： Choi S,Boston JR,Antaki JF

更新日期：2007-02-01 00:00:00