Intravascular micropump for augmented liver perfusion: first in vivo experience.

Abstract:

:The aim of this study was to assess the in vivo performance of a new microaxial rotary blood pump developed for long-term intraportal implantation. The pump, measuring 7 mm in diameter, has a single stage impeller and is powered by a microelectric motor. The pump was implanted into the portal vein in 13 large white pigs under general anesthesia. All animals recovered after the portal pump implantation, and they were observed until the pump failed. The 2 longest running pumps performed for 40 and 36 h, respectively. Either thrombus formation or technical problems, especially in the bearings, were the main causes of pump failure during the experiment. No local or systemic adverse effects were observed during the portal pumping period. Full recovery of the animals following intraportal pump implantation was achieved. However, further technical improvements to the pump are required to maintain a longer performance in vivo.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Havlík R,Kerkhoffs W,Jiao LR,Schumacher O,Reul H,Habib N

doi

10.1046/j.1525-1594.2001.06772.x

subject

Has Abstract

pub_date

2001-05-01 00:00:00

pages

392-4

issue

5

eissn

0160-564X

issn

1525-1594

pii

aor6772

journal_volume

25

pub_type

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