Numerical Simulation of Nonpulsatile Left Ventricular Bypass.

Abstract:

:A computer simulation was carried out to investigate the influence of nonpulsatile left ventricular assistance on hemodynamics. A simulation circuit was constructed to represent the circulatory system. A source of current was added to denote the nonpulsatile blood pump. The left and right ventricles were replaced by variable compliances. Left heart failure was simulated by decreasing the amount of compliance change of the left ventricle. We introduced a pulsatility indicator (PI) to clarify the pulsatility characteristics in the hemodynamics; this PI was defined as the ratio of the pulse pressure (PP) to the mean aortic pressure (AoP). When nonpulsatile bypass flow increased, the mean AoP, tension time index (TTI), and diastolic pressure time index (DPTI) increased, and cardiac output, PP, and PI decreased. When assisted flow increased with the constant total flow rate, the mean AoP and DPTI changed little; the PP, TTI, and PI decreased, and the endocardial viability rate increased. The PI would be helpful in evaluating the effect of pulsatility.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Mitsui N,Fukunaga S,Koura Y,Morita S,Hotei H,Sueshiro M,Sueda T,Matsuura Y

doi

10.1111/j.1525-1594.1996.tb04494.x

subject

Has Abstract

pub_date

1996-05-01 00:00:00

pages

632-636

issue

5

eissn

0160-564X

issn

1525-1594

journal_volume

20

pub_type

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