Intermittent stops of shear reduce the mechanical damage of red blood cells.

abstract：:The sensitivity of liver allografts to even minimal periods of ischemia currently limits the duration of hepatic preservation prior to liver transplantation. This study evaluates the role of activated carbon hemoperfusion (ACH) for assisting the recovery of canine livers ischemically damaged by a 20-min occlusion of t...

journal_title：Artificial organs

authors： Toledo-Pereyra LH

更新日期：1985-08-01 00:00:00

abstract：:Long-term hemodialysis catheter dwell time in the central vein predisposes to fibrin sheath development, which subsequently causes catheter malfunction or occlusion. In very rare cases, the catheter can be overgrown with fibrin and rigidly connected with the vein or heart structures. This makes its removal almost impo...

journal_title：Artificial organs

authors： Garcarek J,Gołębiowski T,Letachowicz K,Kusztal M,Szymczak M,Madziarska K,Jakuszko K,Zmonarski S,Guziński M,Weyde W,Klinger M

更新日期：2016-05-01 00:00:00

abstract：:Cyclosporine (CyA) has an immunosuppressive effect that might suggest a therapeutic role in idiopathic glomerular conditions. We focused on the optimization of CyA treatment control in patients with idiopathic nephrotic syndrome by using trough-level CyA measurements (C0) and the 2-h postdose levels (C2). Twenty-two p...

journal_title：Artificial organs

authors： Griveas I,Visvardis G,Papadopoulou D,Nakopolou L,Karanikas E,Gogos K,Stavianoudakis G

更新日期：2010-03-01 00:00:00

abstract：:To provide percutaneous access, a new circulatory assist system was developed. We call this newly developed system the modified assist device (MAD). The system is composed of a sac-type blood pump and cannula. Inflow and outflow valves are mounted in the apex and at the side wall 10 cm from the apex of the cannula, re...

journal_title：Artificial organs

authors： Imanishi K,Imachi K,Yoshito H,Isoyama T,Abe Y,Chinzei T,Mabuchi K,Kanda K,Tsutsui N,Suma K,Fujimasa I

更新日期：1996-02-01 00:00:00

abstract：:Thirteen percent of 99 patients undergoing maintenance hemodialysis showed an increased predialysis peripheral blood eosinophil count (mean value of 828 cells/mm3, range 410-2,710). Patients with eosinophilia were predominantly male and evidenced more frequent elevation of total plasma IgE levels. Otherwise, no differ...

journal_title：Artificial organs

authors： Friedberg M,Joffe P,Nielsen B,Nielsen LP

更新日期：1987-04-01 00:00:00

abstract：:In this study two aspects of hybrid functional electrical stimulation (FES) orthoses were investigated: joint motion constraints and FES control strategies. First, the effects of joint motion constraints on the gait of normal subjects were investigated using modern motion analysis systems, including electromyogram (EM...

journal_title：Artificial organs

authors： Yang L,Granat MH,Paul JP,Condie DN,Rowley DI

更新日期：1997-03-01 00:00:00

abstract：:Experimental studies on the effects of scaling on the performance of centrifugal blood pumps were conducted in a closed-loop test rig. For the prototype, eight different impellers of the same outer diameter of 25 mm were tested at 1,500, 2,000, and 2,500 revolutions per minute (rpm) using blood analog as fluid medium....

journal_title：Artificial organs

authors： Wong YW,Chan WK,Yu SC,Chua LP

更新日期：2002-11-01 00:00:00

abstract：:To develop artificial materials for prolonged use in the vascular system, the complicated process of surface-induced thrombosis needs to be better understood. It is documented that certain antihypertensive drugs can inhibit platelet adhesion to an artificial surface; on the other hand, steroid drugs increase platelet ...

journal_title：Artificial organs

authors： Chandy T,Sharma CP

更新日期：1991-06-01 00:00:00

abstract：:This article reviews the clinical, biological, radiological, and pathological procedures and their respective indications for the practical diagnosis of the following various histological patterns of renal osteodystrophy: osteitis fibrosa due to parathyroid hormone (PTH) hypersecretion: osteomalacia or rickets due to ...

journal_title：Artificial organs

authors： Fournier A,Oprisiu R,Hottelart C,Yverneau PH,Ghazali A,Atik A,Hedri H,Said S,Sechet A,Rasolombololona M,Abighanem O,Sarraj A,El Esper N,Moriniere P,Boudailliez B,Westeel PF,Achard JM,Pruna A

更新日期：1998-07-01 00:00:00

abstract：:Transcatheter aortic valve (TAV) replacement has become a viable alternative to surgery for high and intermediate risk patients with severe aortic stenosis. This technology may extend to the younger and lower risk patients. In this population, long-term durability of the TAV is key. Increased leaflet mechanical stress...

journal_title：Artificial organs

authors： Stanová V,Zenses AS,Thollon L,Kadem L,Barragan P,Rieu R,Pibarot P

更新日期：2020-07-01 00:00:00

abstract：:We assessed the relationship of certain clinical variables (including bradykinin [BK] release and dialysis membrane) to initial mean arterial pressure (MAP) reduction in 47 patients requiring continuous renal replacement therapy (CRRT) in an intensive care unit. The pretreatment MAP was 84 +/- 14 mm Hg for the group a...

journal_title：Artificial organs

authors： Stoves J,Goode NP,Visvanathan R,Jones CH,Shires M,Will EJ,Davison AM

更新日期：2001-12-01 00:00:00

abstract：:Traumatic injury is often associated with hemorrhagic shock. Liposome-encapsulated hemoglobin (LEH) is being developed as an artificial oxygen carrier to address post-hemorrhage oxygen and volume deficit. Here, we report a new composition of LEH based on the use of polyethylene glycol (PEG2K ) conjugated with nonphosp...

journal_title：Artificial organs

authors： Yadav VR,Nag O,Awasthi V

更新日期：2014-08-01 00:00:00

abstract：:The weight gain of IVOX devices removed from the first 49 human clinical trials patients after from 1 to 29 days of implantation into the venae caval blood stream has been assessed. Each patient had received sufficient systemic heparin to maintain activated clotting times between 150 and 200 s while the IVOX device wa...

journal_title：Artificial organs

authors： Imai H,Schaap RN,Mortensen JD

更新日期：1994-11-01 00:00:00

abstract：:Thyrotoxic crisis (thyroid storm) is a life-threatening condition. Standard therapy is based on thiamazole, prednisolone, and nonselective beta-blockers. Extracorporeal plasmapheresis is an additional tool for removing circulating thyroxine in patients who do not respond quickly to conventional standard therapy. As th...

journal_title：Artificial organs

authors： Koball S,Hickstein H,Gloger M,Hinz M,Henschel J,Stange J,Mitzner S

更新日期：2010-02-01 00:00:00

abstract：:The undulation pump total artificial heart (UPTAH) is a small implantable total artificial heart. As the UPTAH generates outflow and inflow at the same time, control of the UPTAH is very difficult. Therefore suitable control methods specifically for the UPTAH should be established. Various motor control, left-right fl...

journal_title：Artificial organs

authors： Saito I,Chinzei T,Abe Y,Ishimaru M,Mochizuki S,Ono T,Isoyama T,Iwasaki K,Kouno A,Baba A,Ozeki T,Takiura K,Tohyama T,Nakagawa H,Imachi K

更新日期：2003-01-01 00:00:00

abstract：:A comparative study of the thrombogenicity of several microporous membranes was performed using an ex vivo system simulating the conditions in an artificial lung. A study of platelet adhesion and adsorbed protein layer indicated that the membranes separated into three groups. Copolyurethane membranes adsorbed very few...

journal_title：Artificial organs

authors： Knight PM,Lyman DJ

更新日期：1985-02-01 00:00:00

abstract：:We made miniature modules filled with artificial oxygenator hollow fibers and conducted a simple experiment to study the effect of different membrane structures on the blood. Three types of modules were made: one filled with polyolefin, one filled with polypropylene, and a blank module. The 3 modules were connected th...

journal_title：Artificial organs

authors： Nishida H,Shibuya M,Endo M,Koyanagi H

更新日期：1996-12-01 00:00:00

abstract：:As a preliminary investigation to establish a cryopreservation method suited for bioartificial livers (BALs), three-dimensional (3-D) cryopreservation experiments with fibroblasts were performed, in which the cells were firstly seeded into a porous scaffold, and the scaffold containing the cells was then cryopreserved...

journal_title：Artificial organs

authors： Miyoshi H,Ehashi T,Ohshima N,Jagawa A

更新日期：2010-07-01 00:00:00

abstract：:Mechanical circulatory support (MCS) devices for pediatric patients continue to lag in development behind those for adults. There is no heart pump with the design innovation to support dysfunctional states of heart failure and the anatomic heterogeneity of cardiac defects in pediatric patients. To address this unmet n...

journal_title：Artificial organs

authors： Fox C,Sarkisyan H,Stevens R,Arabia F,Fischer W,Rossano J,Throckmorton A

更新日期：2019-11-01 00:00:00

abstract：:The heparin-conjugated fibrin (HCF) system has been developed to deliver bone morphogenetic proteins (BMPs) for a long-term period and thus enhance bone regeneration. In the present study, we tested the effectiveness of the delivery system for spinal fusion with a very low dose of BMP-2. A total of 15 rabbits underwen...

journal_title：Artificial organs

authors： Koo KH,Lee JM,Ahn JM,Kim BS,La WG,Kim CS,Im GI

更新日期：2013-05-01 00:00:00

abstract：:As known from patients with pulsatile ventricular assist devices (VADs), early mobilization, physical exercise, and return to normal life are essential for optimal recovery. Recently, implantable rotary pumps became available for extended left ventricular support as bridges to transplantation. Modified procedures are ...

journal_title：Artificial organs

authors： Wieselthaler GM,Schima H,Dworschak M,Quittan M,Nuhr M,Czerny M,Seebacher G,Huber L,Grimm M,Wolner E

更新日期：2001-05-01 00:00:00

abstract：:We designed a 24-field array and an on-line control box that selects which and how many of 24 fields will conduct electrical charge during functional electrical stimulation. The array was made using a conductive microfiber textile, silver two-component adhesive, and the conductive ink imprint on the polycarbonate. The...

journal_title：Artificial organs

authors： Popović-Bijelić A,Bijelić G,Jorgovanović N,Bojanić D,Popović MB,Popović DB

更新日期：2005-06-01 00:00:00

abstract：:Few instruments are currently available to test mitral valve function in an ex vivo state due to the technical difficulties involved. To investigate the native ex vivo mitral valve or prosthetic mitral valve with chordae, we developed a mitral valve adapter with an annulus suturing portion and 2 papillary muscle sutur...

journal_title：Artificial organs

authors： Katoh T,Ikeda N,Nishi K,Gohra H,Hamano K,Noda H,Fujimura Y,Esato K

更新日期：1999-10-01 00:00:00

abstract：:A 68-year-old woman with fulminant hepatic failure of unknown etiology was treated with a bioartificial liver assist device. Prior to treatment, she had a number of clinical and laboratory features that suggested a hopeless outcome. Treatment was associated with a dramatic change in her mental status, and her clinical...

journal_title：Artificial organs

authors： Sussman NL,Kelly JH

更新日期：1993-01-01 00:00:00

abstract：:We aimed to investigate whether acellular endocardium can be used as a useful biomaterial for the intima of engineered small-caliber vascular grafts. Fresh endocardium was harvested from the swine left atrium and was decellularized by digestion with the decellularization solution of Triton X-100 and SDS containing DNa...

journal_title：Artificial organs

authors： Wang F,Guan X,Wu T,Qiao J,Han Z,Wu J,Yu X,You Q

更新日期：2016-12-01 00:00:00

abstract：:Sponge-type small-diameter vascular grafts were fabricated from a medical-grade polyurethane, Pellethane 2363-80A, by utilization of a salt casting technique. The grafts were compliance matched with a storage modulus of 0.53 +/- 0.08 MPa. The luminal surface of grafts was modified with a thin layer ( approximately 40 ...

journal_title：Artificial organs

authors： Hsu SH,Sun SH,Chen DC

更新日期：2003-12-01 00:00:00

abstract：:What the most causative factor affecting hemolysis is still controversial. To resolve this problem, we investigated the relationship between hemolysis and heat generation in six types of centrifugal blood pumps (Bio-Pump, Delphin, Capiox, Nikkiso, Isoflow, and Toyobo). The analyzed parameters were index of hemolysis i...

journal_title：Artificial organs

authors： Araki K,Taenaka Y,Masuzawa T,Tatsumi E,Wakisaka Y,Watari M,Nakatani T,Akagi H,Baba Y,Anai H

更新日期：1995-09-01 00:00:00

abstract：:Aortic wall thinness was one of the most characteristic changes observed in experimental animals under prolonged continuous flow left heart bypass. The goal of this study was to determine the roles of smooth muscle cells in the vascular remodeling process in cases demonstrating aortic wall thinness under prolonged con...

journal_title：Artificial organs

authors： Mizuno T,Nishinaka T,Ohnishi H,Tatsumi E,Tsukiya T,Oshikawa M,Shioya K,Takewa Y,Homma A,Takano H,Kitamura S,Taenaka Y

更新日期：2003-10-01 00:00:00

abstract：:Although current continuous-flow total artificial hearts (CFTAHs) are much smaller than previous models, venous kinking may still occur after device implantation, especially in smaller animals. By inserting a self-expanding stent at the site of venous narrowing in a sheep model implanted with a CFTAH, we were able to ...

journal_title：Artificial organs

authors： Tuzun E,Parnis S,Rios J,Winkler JA,Cohn WE

更新日期：2011-07-01 00:00:00

abstract：:The optimal anticoagulation regimen for hemodialysis (HD) in patients with heparin-induced thrombocytopenia (HIT) has not been defined. Hemodiafiltration (HDF) adds a large convective component to HD, thereby changing the pharmacokinetics of most anticoagulants. Data on coagulation regimens for HDF are scant. We there...

journal_title：Artificial organs

authors： Mahieu E,Claes K,Jacquemin M,Evenepoel P,Op De Beek K,Bogaert AM,Kuypers D,Verhamme P,Meijers B

更新日期：2013-05-01 00:00:00