Improved liver function following treatment with an extracorporeal liver assist device.

Abstract:

:A 68-year-old woman with fulminant hepatic failure of unknown etiology was treated with a bioartificial liver assist device. Prior to treatment, she had a number of clinical and laboratory features that suggested a hopeless outcome. Treatment was associated with a dramatic change in her mental status, and her clinical picture improved progressively during 6 days of continuous therapy. Evidence of recovery of native liver function allowed the discontinuation of treatment, and she continued to improve for a further 3 1/2 days before her demise from septic shock. We propose that a metabolically active liver assist device is a logical and practical method for treating the critical phase of fulminant hepatic failure.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Sussman NL,Kelly JH

doi

10.1111/j.1525-1594.1993.tb00381.x

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

27-30

issue

1

eissn

0160-564X

issn

1525-1594

journal_volume

17

pub_type

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