Heparin-conjugated poly(lactic-co-glycolic acid) nanospheres enhance large-wound healing by delivering growth factors in platelet-rich plasma.

abstract：:Pyridoxalated-hemoglobin-polyoxyethylene conjugate (PHP), which is made from out-dated human red blood cells by two major chemical modifications, namely pyridoxalation and conjugation with polyoxyethylene (POE), is currently under development as a physiological oxygen carrier. This study assessed the effects of PHP-88...

journal_title：Artificial organs

authors： Takahashi T,Iwasaki K,Malchesky PS,Harasaki H,Matsushita M,Nosé Y,Rolin H 3rd,Hall PM

更新日期：1993-03-01 00:00:00

abstract：:The growing practice of dialyzer reuse in recent years is mainly based on medical and economic considerations. However, adverse reactions such as immunohemolytic anemia due to anti-Nform antibody associated with dialyzer reuse have been reported. In this study, scanning electron microscopy and cytologic staining were ...

journal_title：Artificial organs

authors： Ng YY,Yang AH,Wong KC,Lan HY,Hung TL,Kerr PG,Huang TP

更新日期：1996-01-01 00:00:00

abstract：:Nonpulsatile blood pumps are mainly used in extracorporeal life support systems. Although pulsating blood flow is known to be physiological, a pulsatile pump is not commonly applied in a circuit with a membrane oxygenator because of damage to the blood cells. The hypothesis that the placement of a pressure-relieving c...

journal_title：Artificial organs

authors： Kim TS,Sun K,Lee KB,Lee HW,Baek KJ,Park SY,Son HS,Kim KT,Kim HM

更新日期：2004-12-01 00:00:00

abstract：:Long-term hemodialysis catheter dwell time in the central vein predisposes to fibrin sheath development, which subsequently causes catheter malfunction or occlusion. In very rare cases, the catheter can be overgrown with fibrin and rigidly connected with the vein or heart structures. This makes its removal almost impo...

journal_title：Artificial organs

authors： Garcarek J,Gołębiowski T,Letachowicz K,Kusztal M,Szymczak M,Madziarska K,Jakuszko K,Zmonarski S,Guziński M,Weyde W,Klinger M

更新日期：2016-05-01 00:00:00

abstract：:Rheologic factors are likely to influence the balance between thrombotic and antithrombotic forces at the level of the vascular wall. In this study, the effects of flow-velocity/wall shear stress on the interaction of antithrombin (AT) with surface-immobilized heparin were investigated. The binding of AT to low-affini...

journal_title：Artificial organs

authors： Pasche B,Elgue G,Olsson P,Riesenfeld J,Rasmuson A

更新日期：1991-12-01 00:00:00

abstract：:As the aortic valve (AV) opens, the pump pressure head remains constant, which is reflected as a "notch/plateau" in pump pressure and flow signals. However, instantaneous flow estimation may be influenced by friction and is particularly difficult in axial pumps. Therefore, a new method to determine the duration of AV ...

journal_title：Artificial organs

authors： Hayward C,Lim CP,Schima H,Macdonald P,Moscato F,Muthiah K,Granegger M

更新日期：2015-08-01 00:00:00

abstract：:A review and analysis of 5,001 neonatal venoarterial (VA) extracorporeal membrane oxygenation (ECMO) cases showed that bacterial and fungal infection occurred in 147 (2.9%) and 26 (0.6%) patients, respectively, with an overall incidence of 3.5%. Bivariate analysis was used to compare infected infants with controls, ba...

journal_title：Artificial organs

authors： Douglass BH,Keenan AL,Purohit DM

更新日期：1996-03-01 00:00:00

abstract：:The objective of this study was to compare the hemodynamic performances and gaseous microemboli (GME) handling ability of two pediatric oxygenators in a simulated pediatric cardiopulmonary bypass (CPB) model and the importance of adding an arterial filter in the circuit. The circuit consisted of a Braile Infant oxygen...

journal_title：Artificial organs

authors： Wang S,Caneo LF,Jatene MB,Jatene FB,Cestari IA,Kunselman AR,Ündar A

更新日期：2017-09-01 00:00:00

abstract：:The VentrAssist pump has no shaft or seal, and the device is unique in design because the rotor is suspended passively by hydrodynamic forces, and urging is accomplished by an integrated direct current motor rotor that also acts as the pump impeller. This device has led to many challenges in its fluidic design, namely...

journal_title：Artificial organs

authors： Tansley G,Vidakovic S,Reizes J

更新日期：2000-06-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB) is a nonphysiologic environment for an organism. The damage of blood components may also lead to organ dysfunction, some-times recognized as postperfusion syndrome. One possible way to diminish the risk of these complications would be to reduce the thorombogenicity and to improve the bioco...

journal_title：Artificial organs

authors： Horimoto H,Kondo K,Asada K,Sasaki S

更新日期：1996-08-01 00:00:00

abstract：:A pneumatically driven artificial heart with a tubular silicone rubber membrane and disc valves was used for functional heart replacement in the paracorporeal mode. A fluidic drive system allows adjustment of the heart rate, positive and negative pressures and systole/diastole ratio. Since August, 1977, the artificial...

journal_title：Artificial organs

authors： Turina MT,Bosio R,Senning A

更新日期：1978-08-01 00:00:00

abstract：:Neurological morbidity is a major concern in pediatric cardiac surgery. Cardiopulmonary bypass is one of the few modifiable factors affecting neurodevelopmental outcome. This study aimed to measure the incidence of abnormalities apparent by magnetic resonance imaging (MRI) after neonatal arterial switch operation usin...

journal_title：Artificial organs

authors： Durandy Y,Rubatti M,Couturier R,Rohnean A

更新日期：2011-11-01 00:00:00

abstract：:The trend in neural prostheses using selective nerve stimulation for electrical stimulation therapies is headed toward single-part systems having a large number of working electrodes (WEs), each of which selectively stimulate neural tissue or record neural response (NR). The present article reviews the electrochemical...

journal_title：Artificial organs

authors： Pečlin P,Mehle A,Karpe B,Rozman J

更新日期：2015-10-01 00:00:00

abstract：:There has been increasing interest in the development of a hepatocyte bioreactor for the treatment of acute hepatic failure; however, little is known about the effect of hepatocyte byproducts on the viability of the cells in the bioreactor environment. We investigated the effects of increasing concentrations of bile o...

journal_title：Artificial organs

authors： Smirthwaite AD,Gaylor JD,Cousins RB,Grant MH

更新日期：1998-10-01 00:00:00

abstract：:A totally implantable centrifugal artificial heart has been developed in which a pivot bearing supported centrifugal pump is used as a blood pump. The following have been adopted as blood contacting materials in our pump: titanium alloy (Ti-6A1-4V) for the housing and impeller, alumina ceramic (Al2O3) for the male piv...

journal_title：Artificial organs

authors： Takami Y,Yamane S,Makinouchi K,Niimi Y,Sueoka A,Nosé Y

更新日期：1998-09-01 00:00:00

abstract：:The combination of plasma exchange and continuous hemofiltration was applied to patients with acute liver failure, and its clinically advantageous effects were evaluated. This procedure was found to be a powerful approach in decreasing patient morbidity; however, the effect was temporary and the patients finally died....

journal_title：Artificial organs

authors： Matsubara S

更新日期：1994-05-01 00:00:00

abstract：:In vitro cardiovascular device performance evaluation in a mock circulation loop (MCL) is a necessary step prior to in vivo testing. A MCL that accurately represents the physiology of the cardiovascular system accelerates the assessment of the device's ability to treat pathological conditions. To serve this purpose, a...

journal_title：Artificial organs

authors： Timms DL,Gregory SD,Greatrex NA,Pearcy MJ,Fraser JF,Steinseifer U

更新日期：2011-04-01 00:00:00

abstract：:Adsorption therapy, which treats the autoimmune disease by the selective removal of pathogenic substances from the blood, is an active subject. In this therapy, bioactive molecules such as antigen, antibodies and protein A are usually used as affinity-ligands. The disadvantages of using these substances as affinity-li...

journal_title：Artificial organs

authors： Yamamoto Y,Sameshima T,Akaike T

更新日期：1990-10-01 00:00:00

abstract：:Planar particle image velocimetry was used to explore the flow behavior of the newly designed 12-cc Penn State pneumatic pediatric assist pump. Wall shear maps complemented the velocity data. Bjork-Shiley Monostrut 17-mm mechanical heart valves were used in the inlet and outlet ports. In comparison with larger Penn St...

journal_title：Artificial organs

authors： Manning KB,Wivholm BD,Yang N,Fontaine AA,Deutsch S

更新日期：2008-06-01 00:00:00

abstract：:Many patients who receive a prosthetic heart valve also have or acquire cardiac arrhythmias. However, most in vitro studies of prosthetic valves examine them under normal rhythms. In this study, a monoleaflet prosthetic heart valve was tested in vitro under conditions that simulated normal sinus rhythm, first degree a...

journal_title：Artificial organs

authors： Zapanta CM

更新日期：2005-08-01 00:00:00

abstract：:The aim of this work is the evaluation of four different heat exchangers used for myocardium during cardioplegic system in cardiac surgeries. Four types of shell and tube heat exchangers made of different exchange elements were constructed, as follows: stainless steel tubes, aluminium tubes, polypropylene hollow fiber...

journal_title：Artificial organs

authors： Drummond M,Novello WP,de Arruda AC,Braile DM

更新日期：2003-05-01 00:00:00

abstract：:Aseptic joint loosening is a key factor that reduces the life span of arthroplasty. There are currently few effective treatments for joint loosening except surgical revision. We explored the inhibitory effects of tumor necrosis factor (TNF)-alpha-targeted small interfering RNA (siRNA) on particle-induced inflammatory ...

journal_title：Artificial organs

authors： Qin CQ,Ding Y,Huang DS,Xu J,Ma RF,Huang JB

更新日期：2011-07-01 00:00:00

abstract：:To assess the efficiency of respiratory gas exchange in vitro through a dialysis membrane mounted inside a flat plate Kiil dialyzer, the model reactions of hydrogen peroxide reduction by a metal ion and of the carbon dioxide precipitation in the form of a carbonate in the dialysate were used. A comparison of the rates...

journal_title：Artificial organs

authors： Zborowski M

更新日期：1983-05-01 00:00:00

abstract：:Only a small number of English hospitals provide postcardiotomy venoarterial extracorporeal membrane oxygenation (VA-ECMO) and there are doubts about its efficacy and safety. The aim of this service evaluation was to determine local survival rates and report on patient demographics. This was a retrospective service ev...

journal_title：Artificial organs

authors： Charlesworth M,Garcia M,Head L,Barker JM,Ashworth AD,Barnard JB,Feddy L,Venkateswaran RV

更新日期：2020-07-01 00:00:00

abstract：:The multi-output adaptive controller of a left ventricular assist device (LVAD) was studied by computer simulation. The controller regulated two outputs--mean aortic pressure (mAoP) and mean atrial pressure (mLAP)--by regulating vacuum pressure (input). The autoregressive models were used to describe the circulatory s...

journal_title：Artificial organs

authors： Shimooka T,Mitamura Y,Yuhta T

更新日期：1991-04-01 00:00:00

abstract：:Ventricular assist devices (VADs) are considered the standard of care for end-stage heart failure (HF) patients. Despite increasing confidence in the technology, evidence data, endorsement by scientific societies and guidelines, the number of implants reached a steady state and is not increasing at the expected pace. ...

journal_title：Artificial organs

authors： Barbone A,Pagliaro B,Basciu A,Iaccarino A,Droandi G,Romano G,Citterio E,Fumero A,Torracca L,Pini D

更新日期：2020-04-23 00:00:00

abstract：:Veno-arterial extracorporeal membrane oxygenation (ECMO) may be implanted using peripheral ECMO (pECMO) or central ECMO (cECMO) cannulation techniques. The aim of this study was to compare the outcome between these two cannulation techniques. A retrospective study was performed at Düsseldorf University Hospital from O...

journal_title：Artificial organs

authors： Saeed D,Stosik H,Islamovic M,Albert A,Kamiya H,Maxhera B,Lichtenberg A

更新日期：2014-07-01 00:00:00

abstract：:The developments in apheresis techniques and their clinical applications world-wide are technologically driven. In the past, apheresis survey statistics have high-lighted both the differences by region in clinical practice and in the types of technologies utilized. Such differences have provided a basis for the scient...

journal_title：Artificial organs

authors： Malchesky PS,Bambauer R,Horiuchi T,Kaplan A,Sakurada Y,Samuelsson G

更新日期：1995-04-01 00:00:00

abstract：:The aim of this study was to evaluate the efficiency of hemoperfusion (HP) through coated resin adsorbent Synachrom E-5 in animal intoxications with organophosphate inhibitors of cholinesterases type of nerve agents. Five anesthetized dogs were intoxicated with 2 to 6 LD50 of VX substance and another 4 with 2 to 3 LD5...

journal_title：Artificial organs

authors： Monhart V,Fusek J,Brndiar M,Tlustakova M

更新日期：1994-10-01 00:00:00

abstract：:Left dominant biventricular failure is a common type of heart failure after cardiac surgery. We developed a biventricular bypass (BVB) system for treatment of postcardiotomy ventricular failure, and we previously reported that the clinical results of the BVB system were superior to those obtained with venoarterial byp...

journal_title：Artificial organs

authors： Kodera K,Kitamura M,Shibuya M,Kurihara H,Koyanagi H

更新日期：1998-09-01 00:00:00