A compact mock circulation loop for the in vitro testing of cardiovascular devices.

abstract：:Eight patients were studied during four sessions of acetate-free biofiltration (AFBF). AFBF is a new dialysis technique with no base replacement agents in the dialysate and with the addition in postdilution mode of bicarbonate (HCO3) solution directly into the extracorporeal blood circuit. In this study the effects on...

journal_title：Artificial organs

authors： Santoro A,Ferrari G,Spongano M,Badiali F,Zucchelli P

更新日期：1989-10-01 00:00:00

abstract：:Plasma procoagulant activities of factors XII, XI, IX, and VIII and plasma concentrations of factor XII antigen and high molecular weight kininogen (HMK) were determined in nine men with chronic renal failure (CRF) associated with long-standing spinal cord injury (SCI) treated with hemodialysis. The results were compa...

journal_title：Artificial organs

authors： Vaziri ND,Winer RL,Toohey J,Danviriyasup K,Alikhani S,Eltorai I,Gordon S,Paule P

更新日期：1985-05-01 00:00:00

abstract：:Modular hip prostheses are commonly used today. Dedicated surgical auxiliary instrumentation is indispensable. A correct coupling between the prosthesis and the instrument is necessary to avoid damage. Based on a specific commercial design (AnCAFit, Wright Cremascoli Ortho, Toulon, France), the aim of this work was to...

journal_title：Artificial organs

authors： Varini E,Cristofolini L,Viceconti M,Traina F

更新日期：2006-07-01 00:00:00

abstract：:We compared in vitro rates of hemolysis for a recently developed centrifugal pump with a conventional roller pump (10-10-00; Stöckert, Munich, Germany). Flow rates of 0.3 L/min and 1 L/min and a pressure of 200 mm Hg were chosen to simulate conditions during neonatal extracorporeal membrane oxygenation (ECMO). There w...

journal_title：Artificial organs

authors： Moon YS,Ohtsubo S,Gomez MR,Moon JK,Nose Y

更新日期：1996-05-01 00:00:00

abstract：:From January 1980 through December 1990, implantation of a permanent pacemaker was performed in 34 patients following open heart surgery. The patients were divided into two groups according to the clinical indications for implantation of permanent pacemakers. Group 1 (9 patients) had surgical atrioventricular block, a...

journal_title：Artificial organs

authors： Otaki M

更新日期：1993-05-01 00:00:00

abstract：:Transplanted allogeneic marrow grafts often fail to engraft in a lethally irradiated host. Resistance to hemopoietic allograft is a complexed phenomenon involving multiple components. To study the involvement of a hemopoietic cytokine, which was known to play a role for stem cell function, we established lines of mice...

journal_title：Artificial organs

authors： Kokai Y,Kimura H,Matsuura A,Fujimoto J

更新日期：1996-08-01 00:00:00

abstract：:Patients with kidney failure can only survive with some form of kidney replacement (transplant or dialysis). Unfortunately, innovations in kidney replacement therapy lag behind many other medical fields. This study compiles expert opinions on candidate technologies for future kidney replacement therapies. A worldwide ...

journal_title：Artificial organs

authors： Pereira Cabral B,Bonventre JV,Wieringa F,Mota FB

更新日期：2020-07-22 00:00:00

abstract：:Molecular Adsorbent Recirculating System (MARS) is a liver support system widely employed in the treatment of liver failure. The method is normally well tolerated. To develop a liver support system combining high efficiency and tolerability, we modified the MARS albumin circuit with the insertion of double adsorption ...

journal_title：Artificial organs

authors： Marangoni R,Bellati G,Castelli A,Romagnoli E

更新日期：2014-10-01 00:00:00

abstract：:Magnevad II is an improved version of Magnevad I and both are fourth-generation axial flow left ventricular assist devices. A major simplification has been implemented and tested. Magnevad I used a magnetically suspended rotor requiring active axial control. Magnevad II is completely passive but otherwise similar. A s...

journal_title：Artificial organs

authors： Goldowsky M,Lafaro R,Reed G

更新日期：2005-10-01 00:00:00

abstract：:In transplantation surgery, extending the criteria for organ donation to include organs that may have otherwise been previously discarded has provided the impetus to improve organ preservation. The traditional method of cold static storage (CS) has been tried and tested and is suitable for organs meeting standard crit...

journal_title：Artificial organs

authors： Kumar R,Chung WY,Dennison AR,Garcea G

更新日期：2017-09-01 00:00:00

abstract：:Modeling different treatment options before a procedure is performed is a promising approach for surgical decision making and patient care in heart valve disease. This study investigated the hemodynamic impact of different prostheses through patient-specific MRI-based CFD simulations. Ten time-resolved MRI data sets w...

journal_title：Artificial organs

authors： Hellmeier F,Nordmeyer S,Yevtushenko P,Bruening J,Berger F,Kuehne T,Goubergrits L,Kelm M

更新日期：2018-01-01 00:00:00

abstract：:To perform the first experimental tests for validation of a new gear unit concept, the pump chamber, diaphragm, and pusher plate design of an orthotopic electromechanical total artificial heart (TAH) (Helmholtz Labtype) was manufactured. In its early stage of development, it provides some of the most important feature...

journal_title：Artificial organs

authors： Kaufmann R,Reul H,Rau G

更新日期：1994-07-01 00:00:00

abstract：:We have been developing a new type of centrifugal pump for long-term use. The magnetically suspended centrifugal pump (MSCP) contains no shaft and seal so that long life expectancy is predicted. Paracorporeal left ventricular (LV) assist circulation between the left atrium and the descending aorta was instituted using...

journal_title：Artificial organs

authors： Yamada T,Nishimura K,Park CH,Kono S,Yuasa S,Tsukiya T,Akamatsu T,Matsuda K,Ban T

更新日期：1997-07-01 00:00:00

abstract：:The aim of this study was to compare patients with severe biventricular heart failure who underwent Berlin Heart Excor implantation with (cardiogenic shock [CS] status) or without the need for preoperative extracorporeal life support (ECLS) as a bridge to long-term device. A total of 40 consecutive patients with sever...

journal_title：Artificial organs

authors： Weymann A,Farag M,Sabashnikov A,Fatullayev J,Zeriouh M,Schmack B,Arif R,Müller F,Alt C,Raake P,Prakash Patil N,Popov AF,Rüdiger Simon A,Karck M,Ruhparwar A,Heidelberg-Cologne-Harefield Cardiothoracic Transplantation & Mecha

更新日期：2017-06-01 00:00:00

abstract：:Neurological morbidity is a major concern in pediatric cardiac surgery. Cardiopulmonary bypass is one of the few modifiable factors affecting neurodevelopmental outcome. This study aimed to measure the incidence of abnormalities apparent by magnetic resonance imaging (MRI) after neonatal arterial switch operation usin...

journal_title：Artificial organs

authors： Durandy Y,Rubatti M,Couturier R,Rohnean A

更新日期：2011-11-01 00:00:00

abstract：:Long-term hemodialysis catheter dwell time in the central vein predisposes to fibrin sheath development, which subsequently causes catheter malfunction or occlusion. In very rare cases, the catheter can be overgrown with fibrin and rigidly connected with the vein or heart structures. This makes its removal almost impo...

journal_title：Artificial organs

authors： Garcarek J,Gołębiowski T,Letachowicz K,Kusztal M,Szymczak M,Madziarska K,Jakuszko K,Zmonarski S,Guziński M,Weyde W,Klinger M

更新日期：2016-05-01 00:00:00

abstract：:Patients with end-stage renal failure and peripheral vascular disease pose a difficult management problem in establishing long-term angioaccess for hemodialysis. In 4 patients with access problems, we created axillary artery to contralateral axillary vein Goretex grafts. The grafts were cannulated regularly for period...

journal_title：Artificial organs

authors： Ono K,Muto Y,Yano K,Yukizane T

更新日期：1995-12-01 00:00:00

abstract：:A belt worn controller and lithium-ion battery pack have been developed for use with the initial clinical trials of the Jarvik 2000 heart. Patient interface considerations, safety, and simplicity were major design inputs for the system. The controller was developed using all analog technology to avoid difficulties wit...

journal_title：Artificial organs

authors： Jarvik R,Scott V,Morrow M,Takecuhi E

更新日期：1999-06-01 00:00:00

abstract：:The neutralization of bacterial endotoxins (ET) is still an unsolved problem in therapeutic medicine. The efficacy of anti-endotoxin antibodies or receptor antagonists and other substances interfering with the endotoxin-induced pathomechanisms is dependent on an intact cellular degradation system of the host. However,...

journal_title：Artificial organs

authors： Mitzner S,Schneidewind J,Falkenhagen D,Loth F,Klinkmann H

更新日期：1993-09-01 00:00:00

abstract：:Over a 4 year period, five of 98 patients at our dialysis unit developed signs and symptoms consistent with first-use syndrome (FUS). Marked improvement was noted after subjecting new dialyzers to automated processing using either formaldehyde or peracetic acid. No episodes of FUS occurred in patients being treated wi...

journal_title：Artificial organs

authors： Vanholder R,Ringoir S

更新日期：1987-04-01 00:00:00

abstract：:Total artificial hearts (TAHs) and biventricular assist devices (BVADs) have varying levels of acceptance and reliability, and the research on both focuses on their control mechanisms. Efforts generally aim to achieve a response to physiologic demand and left/right output balance, and beneficial cardiac output (CO) an...

journal_title：Artificial organs

authors： Hall AW,Soykan O,Harken AH

更新日期：1996-03-01 00:00:00

abstract：:Ten dialysis patients were followed in a prospective study to determine the neurotoxicity of metabolites in the middle molecule (MM) molecular weight (mol wt) range of 500-200 daltons/molecule. In the absence of readily available direct serum measurements of MM concentrations, a theoretically calculated dialysis index...

journal_title：Artificial organs

authors： Milutinovic J,Babb AL,Eschbach JW,Follette WC,Graefe U,Strand MJ,Scribner BH

更新日期：1978-02-01 00:00:00

abstract：:The present study aimed to determine the feasibility of constructing a reinforced autologous vascular graft by combining the advantages of fibrin gel as an autologous cell carrier material with the inherent mechanical strength of an integrated mesh structure. It was hypothesized that the mesh and dynamic culture condi...

journal_title：Artificial organs

authors： Tschoeke B,Flanagan TC,Cornelissen A,Koch S,Roehl A,Sriharwoko M,Sachweh JS,Gries T,Schmitz-Rode T,Jockenhoevel S

更新日期：2008-10-01 00:00:00

abstract：:The effects of Fluosol-DA 20% on circulating blood cells, hemodynamic parameters, blood gases, and organs are described and compared with the results of phase I human studies and animal experiments. Bleeding of preoperative anemia and/or surgical bleeding, Fluosol-DA 20% was administered to 7 of 10 Jehovah's Witness p...

journal_title：Artificial organs

authors： Ohyanagi H,Nakaya S,Okumura S,Saitoh Y

更新日期：1984-02-01 00:00:00

abstract：:A computer simulation was carried out to investigate the influence of nonpulsatile left ventricular assistance on hemodynamics. A simulation circuit was constructed to represent the circulatory system. A source of current was added to denote the nonpulsatile blood pump. The left and right ventricles were replaced by v...

journal_title：Artificial organs

authors： Mitsui N,Fukunaga S,Koura Y,Morita S,Hotei H,Sueshiro M,Sueda T,Matsuura Y

更新日期：1996-05-01 00:00:00

abstract：:We report on the most recent data confirming the angiographic and pathological efficacy of LDL-apheresis for coronary atherosclerosis of a familial hypercholesterolemia (FH) patient using collected data of a large number of cases and especially of one autopsy case. Changes in coronary artery stenosis have been assesse...

journal_title：Artificial organs

authors： Koga N,Iwata Y,Yamamoto A

更新日期：1992-04-01 00:00:00

abstract：:The blood flow through the hemofilter device is the key point for ultrafiltrate production during continuous arteriovenous hemofiltration. It mainly depends on arteriovenous pressure gradient and vascular access, which is the major problem for arteriovenous hemofiltration in infants and small children. In infants, we ...

journal_title：Artificial organs

authors： Zobel G,Trop M,Beitzke A,Ring E

更新日期：1988-02-01 00:00:00

abstract：:The effects of pyridoxalated hemoglobin polyoxyethylene conjugate (PHP) and other hemoglobin-related substances on arterial blood pressure (ABP) and heart rate (HR) were examined. Infusion of PHP and other hemoglobin-related substances elevated ABP and increased HR. The degree of the increase in ABP and HR did not dif...

journal_title：Artificial organs

authors： Kida Y,Maeda M,Iwata S,Iwashita Y,Goto K,Nishi K

更新日期：1995-02-01 00:00:00

abstract：:To evaluate the potential clinical usefulness of a modified hemoglobin, pyridoxalated hemoglobin polyoxyethylene conjugate (PHP), the hindlimb vascular bed was perfused with PHP solution while monitoring tissue oxygen tension (PtO2) in anesthetized dogs. The hindlimb region was perfused through the external iliac arte...

journal_title：Artificial organs

authors： Kida Y,Yamakawa T,Iwasaki S,Furusho N,Kadowaki Y,Iwata S,Iwashita Y,Nishi K

更新日期：1995-06-01 00:00:00

abstract：:An important present and emerging trend in biomaterials development is the synthesis of polymers which combine capabilities of biologic recognition ("biomimetic") with sensitivity to small environmental changes ("stimuli-responsive"). This short article highlights some of the many opportunities and challenges in this ...

journal_title：Artificial organs

authors： Hoffman AS

更新日期：1988-12-01 00:00:00