Abstract:
:Ventricular assist devices (VADs) are considered the standard of care for end-stage heart failure (HF) patients. Despite increasing confidence in the technology, evidence data, endorsement by scientific societies and guidelines, the number of implants reached a steady state and is not increasing at the expected pace. This is most likely related to complications that are still burdening the technology and consequently excluding the most needy, ill, and fragile population. In this manuscript we are reporting a single-center experience in a very fragile, elderly and end-stage HF population, with a superficial, partial support device: the CircuLite Synergy. The patients were included in the pre-CE mark clinical study and consequently the device underwent technical adjustment during the support, based on the complications recorded. At our institution were implanted 6 patients overall: 3 patients survived to discharge and 2 survived up to 5 years. Most of the complications recorded were due to patients' frailty and overall clinical conditions. The initial experience with the CircuLite Synergy device is proving that a more "superficial" device might be more tolerable in an elderly, frail population. Partial support has proven hemodynamically efficacious and efficient in relieving heart failure symptoms, improving medical therapy tolerability, and improving quality of life. Unfortunately, the technology was not made available due to financial uncertainty and poor management, but we hope that once the concept has been proved someone will collect the legacy.
journal_name
Artif Organsjournal_title
Artificial organsauthors
Barbone A,Pagliaro B,Basciu A,Iaccarino A,Droandi G,Romano G,Citterio E,Fumero A,Torracca L,Pini Ddoi
10.1111/aor.13714subject
Has Abstractpub_date
2020-04-23 00:00:00eissn
0160-564Xissn
1525-1594pub_type
杂志文章abstract::Doppler ultrasound is a noninvasive technique for monitoring moving objects such as flowing blood while ignoring stationary objects such as shunt tubing. A Doppler system was investigated to determine its sensitivity in detecting particulate release in blood during hemodialysis. Seven hemodialysis procedures with dogs...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1984.tb04275.x
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journal_title:Artificial organs
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journal_title:Artificial organs
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pub_type: 杂志文章
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journal_title:Artificial organs
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1995.tb02371.x
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journal_title:Artificial organs
pub_type: 杂志文章
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pub_type: 临床试验,杂志文章
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更新日期:1995-08-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.1999.06426.x
更新日期:1999-08-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章,评审
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journal_title:Artificial organs
pub_type: 杂志文章,评审
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更新日期:1998-07-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.2001.025001053.x
更新日期:2001-01-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2005.29071.x
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pub_type: 杂志文章
doi:10.1111/j.1525-1594.2011.01213.x
更新日期:2011-03-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.2002.06973.x
更新日期:2002-12-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1978.tb03442.x
更新日期:1978-05-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.13484
更新日期:2019-10-01 00:00:00
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journal_title:Artificial organs
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journal_title:Artificial organs
pub_type: 杂志文章
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1990.tb02997.x
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更新日期:2016-11-01 00:00:00
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更新日期:2004-02-01 00:00:00
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更新日期:2002-02-01 00:00:00
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journal_title:Artificial organs
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1996.tb04507.x
更新日期:1996-05-01 00:00:00
abstract::Existing peritoneal dialysis (PD) solutions were formulated for the maintenance of fluid and electrolyte balance, correction of metabolic acidosis, and the removal of metabolic waste products. Solutions currently in development are designed to improve biocompatibility by neutralizing pH and reducing glucose degradatio...
journal_title:Artificial organs
pub_type: 杂志文章,评审
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