Abstract:
:Neurological morbidity is a major concern in pediatric cardiac surgery. Cardiopulmonary bypass is one of the few modifiable factors affecting neurodevelopmental outcome. This study aimed to measure the incidence of abnormalities apparent by magnetic resonance imaging (MRI) after neonatal arterial switch operation using warm surgery. Neonates admitted for transposition of the great arteries underwent pre- and postoperative brain MRI. They were operated on using a warm perfusion method. The data collected included antenatal diagnosis, place of birth, gestational age, total maturation score as described by Childs, weight, cyanosis as assessed by minimal SpO(2) sustained for at least 10 min, balloon atrial septostomy, prostaglandin E1 infusion, need for neonatal intensive care, bypass time, time to extubation, and length of stay in intensive care. All of the MRI results were interpreted by the same senior specialist in pediatric neuroimaging, and lesions were classified as white matter injury, infarct, or hemorrhage. On preoperative exam, nine patients (42%) had one or more lesions, with infarct in four patients, white matter injury in four patients, and hemorrhage in five. We were unable to find any correlation between the data collected and brain injury. On postoperative exam, there was one new infarct, two new cases of white matter injury, and three cases of hemorrhage but no worsening of the preoperative lesions. Based on this initial experience with brain imaging, there is no deleterious effect of warm perfusion and no rationale to postpone surgery in neonates with "subclinical" brain injury.
journal_name
Artif Organsjournal_title
Artificial organsauthors
Durandy Y,Rubatti M,Couturier R,Rohnean Adoi
10.1111/j.1525-1594.2011.01325.xsubject
Has Abstractpub_date
2011-11-01 00:00:00pages
1115-8issue
11eissn
0160-564Xissn
1525-1594journal_volume
35pub_type
杂志文章abstract::This work describes the preparation and characterization of anionic collagen composites with rhamsan and vinylidene fluoride-trifluorethylene with improved rheological and dielectric properties without loss of collagen secondary structure with an interaction occurring between both macromolecules of the composites. On ...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.1998.06109.x
更新日期:1998-03-01 00:00:00
abstract::There is an increasing need for research and development centers to deal with design and evaluation of organ replacement systems, the improvement of older devices, and the study of biocompatibility problems. Special attention, in this article, is focused on the determinant role of the background of the investigators i...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1989.tb01579.x
更新日期:1989-12-01 00:00:00
abstract::A method of creating multifocal ischemia in animals leading to left ventricular (LV) functional impairment is described. In a series of 10 mongrel dogs, electrodes were implanted in multiple branches of the coronary arteries. Subsequently, in seven animals, an 800-microA anodal current was applied for 3 h repeatedly o...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1984.tb04321.x
更新日期:1984-11-01 00:00:00
abstract::The aim of this study was to investigate whether the use of a medically approved biodegradable scaffold as a solid support system would enhance graft survival following transplantation into the omental pouch in a preclinical large animal model. Six beagle dogs underwent total pancreatectomy followed by islet autotrans...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2008.00688.x
更新日期:2008-12-01 00:00:00
abstract::The aim of this work is to construct a computational fluid dynamics model capable of simulating the transient non-Newtonian process of apheresis. A Lagrangian-Eulerian model has been developed which tracks the blood particles within a two-dimensional flow configuration. Within the Eulerian method, the fluid mass and m...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2005.00164.x
更新日期:2005-12-01 00:00:00
abstract::The kinetic features of ultrafiltration of cellulose dialysis membrane stored under various humidity and temperature conditions were studied to obtain basic information of shelf-life characteristics of dialyzers. The ultrafiltration rate (UFR) decreased with time and the UFR-time curve suggested that the UFR would app...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1981.tb04003.x
更新日期:1981-08-01 00:00:00
abstract::No standardized treatment algorithm exists for the management of continuous-flow left ventricular assist device (CF-LVAD)-specific infections. The aim of this systematic review and meta-analysis was to compare the outcomes of CF-LVAD-specific infections as managed by device exchange to other treatment modalities not i...
journal_title:Artificial organs
pub_type: 杂志文章,meta分析
doi:10.1111/aor.13378
更新日期:2019-05-01 00:00:00
abstract::A woven fabric graft made of ultrafine polyester fibers (UFPF) (Toray Graft, water porosity: 100 ml/min/cm2:120 mm Hg H2O) was clinically applied in 81 cases (28 thoracic aortic aneurysms, 6 thoracoabdominal aortic aneurysms, 42 abdominal aortic aneurysms, and 5 atherosclerotic obstructions of the peripheral arteries)...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1995.tb02245.x
更新日期:1995-01-01 00:00:00
abstract::The treatment of rheumatoid arthritis remains difficult and often controversial. Plasma exchange has been advocated in some cases. In the present study 71 sessions of double filtration plasmapheresis (DFPP) were performed in 21 patients with rheumatoid arthritis in an average of 3.7 +/- 1.1 sessions per patient within...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1997.tb00344.x
更新日期:1997-02-01 00:00:00
abstract::Lipid apheresis has developed from a heroic treatment into a routine clinical therapy and currently is the major indication for performing extracorporeal plasma therapy. Whereas it was once reserved for patients with homozygous familial hypercholesterolemia, today it has a place in the secondary prevention of severe c...
journal_title:Artificial organs
pub_type: 杂志文章,评审
doi:10.1111/j.1525-1594.1996.tb04525.x
更新日期:1996-05-01 00:00:00
abstract::In this pilot study, we assessed the feasibility of using positron emission tomography (PET) imaging for in vivo measurement of skeletal muscle ventricle (SMV) tissue blood flow. In 4 dogs, with SMVs prepared from their latissimus dorsi muscle, we quantified SMV tissue blood flow by PET and related it to the tissue fl...
journal_title:Artificial organs
pub_type: 杂志文章
doi:
更新日期:2001-04-01 00:00:00
abstract::The clearance characteristics of two sizes of hemodialyzers (0.9 m2 and 1.5 m2) from the same range of products have been studied over the dialysate flow range of 500-3,000 ml/min to establish the device's overall mass transfer resistance characteristics. The results obtained demonstrate a difference in the overall ma...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1995.tb02279.x
更新日期:1995-11-01 00:00:00
abstract::In vitro cardiovascular device performance evaluation in a mock circulation loop (MCL) is a necessary step prior to in vivo testing. A MCL that accurately represents the physiology of the cardiovascular system accelerates the assessment of the device's ability to treat pathological conditions. To serve this purpose, a...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2010.01088.x
更新日期:2011-04-01 00:00:00
abstract::In this study, the hypothesis was tested that a low-resistant, high-compliant oxygenator provides better pulse conductance and less hemolysis than a high-resistant, low-compliant oxygenator during pulsatile cardiopulmonary bypass. Forty adults undergoing coronary artery bypass surgery were randomly divided into two gr...
journal_title:Artificial organs
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1525-1594.2009.00853.x
更新日期:2010-04-01 00:00:00
abstract::One hundred and seventy-two patients at The Methodist Hospital in Houston, Texas, were placed on BioMedicus centrifugal ventricular support. One hundred thirty-nine patients were male and 33 were female with a mean age of 59.7 years. Reasons for support were postcardiotomy cardiac failure (129 patients), cardiac allog...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1995.tb02419.x
更新日期:1995-07-01 00:00:00
abstract::Many patients who receive a prosthetic heart valve also have or acquire cardiac arrhythmias. However, most in vitro studies of prosthetic valves examine them under normal rhythms. In this study, a monoleaflet prosthetic heart valve was tested in vitro under conditions that simulated normal sinus rhythm, first degree a...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2005.29101.x
更新日期:2005-08-01 00:00:00
abstract::Transplanted allogeneic marrow grafts often fail to engraft in a lethally irradiated host. Resistance to hemopoietic allograft is a complexed phenomenon involving multiple components. To study the involvement of a hemopoietic cytokine, which was known to play a role for stem cell function, we established lines of mice...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1996.tb04563.x
更新日期:1996-08-01 00:00:00
abstract::Over the past several years, we have developed novel titanium-niobium-zirconium (Ti-Nb-Zr) alloys to address the long-term performance needs of orthopedic implants. The unique properties of these alloys also render them promising candidates for blood pumps. These properties include excellent biocompatibility in combin...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1996.tb04473.x
更新日期:1996-05-01 00:00:00
abstract::In previous studies, we presented main strategies for suspending the rotor of a mixed-flow type (centrifugal and axial) ventricular assist device (VAD), originally presented by the Institute Dante Pazzanese of Cardiology (IDPC), Brazil. Magnetic suspension is achieved by the use of a magnetic bearing architecture in w...
journal_title:Artificial organs
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1525-1594.2011.01265.x
更新日期:2011-05-01 00:00:00
abstract::In a multicenter study including 5 dialysis units, blood acetate changes during 4 h dialysis sessions in 141 patients treated with a 4 mM acetate-containing bicarbonate dialysate (ABD) were evaluated and compared to the values of 114 patients using an acetate-free bicarbonate dialysate (AFD). Acetate-free bicarbonate ...
journal_title:Artificial organs
pub_type: 杂志文章,多中心研究
doi:10.1046/j.1525-1594.1998.06205.x
更新日期:1998-07-01 00:00:00
abstract::Thousands of ventricular assist devices (VADs) currently provide circulatory support to patients worldwide, and dozens of heart pump designs for adults and pediatric patients are under various stages of development in preparation for translation to clinical use. The successful bench-to-bedside development of a VAD inv...
journal_title:Artificial organs
pub_type: 杂志文章,评审
doi:10.1111/aor.12600
更新日期:2016-06-01 00:00:00
abstract::We developed a novel miniaturized extracorporeal centrifugal pump "BIOFLOAT NCVC (Nipro Corporation Osaka, Japan) as a ventricular assist device (VAD) and performed a preclinical study that is part of the process for its approval as a bridge to decision by the pharmaceutical and medical device agencies. The aim of thi...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.13459
更新日期:2019-09-01 00:00:00
abstract::Mesenchymal stem cells (MSCs) are regarded as a potential autologous source for cartilage repair, because they can differentiate into chondrocytes by transforming growth factor-beta (TGF-beta) treatment under the 3-dimensional (3-D) culture condition. However, more efficient and versatile methods for chondrogenic diff...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2006.00288.x
更新日期:2006-09-01 00:00:00
abstract::Excessive left ventricular (LV) volume unloading can affect right ventricular (RV) function by causing a leftward shift of the interventricular septum in patients with mitral regurgitation (MR) receiving left ventricular assist device (LVAD) support. Optimal settings for the LVAD should be chosen to appropriately cont...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.12702
更新日期:2016-11-01 00:00:00
abstract::The energy dissipated in blood or on a total artificial heart (TAH) chamber's elements directly or indirectly decreases the biological or technical safety of the TAH's work. The energetic analysis of the Polish total artificial heart (POLTAH) external work with the objective of estimating the valve and membrane roles ...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.1998.05074.x
更新日期:1998-10-01 00:00:00
abstract::A new intravascular pumping oxygenator (IVPO) was developed for intravascular gas exchange and circulatory assistance in critically ill patients with respiratory and circulatory failure. The IVPO utilizes new silicone hollow fibers (diameter, 1 mm; membrane width, 50 microns) and consists of two driving tubes for the ...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1997.tb00703.x
更新日期:1997-01-01 00:00:00
abstract::Biofilms are communities of bacteria that can cause infections which are resistant to the immune system and antimicrobial treatments, posing a significant threat for patients with implantable and indwelling medical devices. The purpose of our research was to determine if utilizing specific parameters for electric curr...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.12678
更新日期:2016-08-01 00:00:00
abstract::For the last few years we have attempted to separate and isolate from biological fluids the uremic Middle Molecules (MM). The first step in the treatment of plasma is an ultrafiltration through AN69 membrane. The samples are fractionated by Sephadex G-15 chromatography into 9 peaks "a" to "i' under precise conditions ...
journal_title:Artificial organs
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::Aortic arch repair in newborns and infants has traditionally been accomplished using a period of deep hypothermic circulatory arrest. To reduce neurologic and cardiac dysfunction related to circulatory arrest and myocardial ischemia during complex aortic arch surgery, an alternative and novel strategy for cerebro-myoc...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.13128
更新日期:2018-04-01 00:00:00
abstract::The polymer poly(ε-caprolactone) (PCL) has been used in the biomaterial field for its relatively inexpensive price and suitability for modification. Also, its chemical and biological properties are desirable for biomedical applications. The electrospinning process has been used for producing polymer fibers of PCL due ...
journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.13713
更新日期:2020-08-01 00:00:00