Research into the development of a wearable bioartificial kidney with a continuous hemofilter and a bioartificial tubule device using tubular epithelial cells.

abstract：:The major problems with existing centrifugal pumps are leakage, mechanical trauma, and thrombus formation. In consideration of these problems, a new compact centrifugal pump system was developed. The purpose of this study was to evaluate the new centrifugal pump system clinically. Ten patients underwent open heart sur...

journal_title：Artificial organs

authors： Ninomiya J,Shoji T,Tanaka S,Ikeshita M,Ochi M,Yamauchi S,Yajima T,Yamauchi H,Sugimoto T,Aizawa T

更新日期：1994-09-01 00:00:00

abstract：:Myointimal hyperplasia (MIH) is an arterial wall smooth muscle cell (SMC) proliferative disorder. This process is responsible for a significant number of early and long-term arterial reconstructive and graft failures. Histopathologically, this process is characterized by a proliferation of SMC in the intima of traumat...

journal_title：Artificial organs

authors： Painter TA

更新日期：1991-02-01 00:00:00

abstract：:The objective of this study was to evaluate an alternative neonatal extracorporeal life support (ECLS) circuit with a RotaFlow centrifugal pump and Better-Bladder (BB) for hemodynamic performance and gaseous microemboli (GME) capture in a simulated neonatal ECLS system. The circuit consisted of a Maquet RotaFlow centr...

journal_title：Artificial organs

authors： Spencer SB,Wang S,Woitas K,Glass K,Kunselman AR,Ündar A

更新日期：2017-01-01 00:00:00

abstract：:This article reviews the clinical, biological, radiological, and pathological procedures and their respective indications for the practical diagnosis of the following various histological patterns of renal osteodystrophy: osteitis fibrosa due to parathyroid hormone (PTH) hypersecretion: osteomalacia or rickets due to ...

journal_title：Artificial organs

authors： Fournier A,Oprisiu R,Hottelart C,Yverneau PH,Ghazali A,Atik A,Hedri H,Said S,Sechet A,Rasolombololona M,Abighanem O,Sarraj A,El Esper N,Moriniere P,Boudailliez B,Westeel PF,Achard JM,Pruna A

更新日期：1998-07-01 00:00:00

abstract：:We tried to verify the hypothesis that increases in pump flow during diastole are matched by decreases in left ventricular (LV) output during systole. A calf (80 kg) was implanted with an implantable centrifugal blood pump (EVAHEART, SunMedical Technology Research Corp., Nagano, Japan) with left ventricle to aorta (LV...

journal_title：Artificial organs

authors： Akimoto T,Litwak KN,Yamazaki K,Litwak P,Kihara SI,Tagusari O,Yamazaki SI,Kameneva MV,Watach MJ,Umezu M,Tomioka J,Kormos RL,Koyanagi H,Griffith BP

更新日期：2001-09-01 00:00:00

abstract：:From January 1980 through December 1990, implantation of a permanent pacemaker was performed in 34 patients following open heart surgery. The patients were divided into two groups according to the clinical indications for implantation of permanent pacemakers. Group 1 (9 patients) had surgical atrioventricular block, a...

journal_title：Artificial organs

authors： Otaki M

更新日期：1993-05-01 00:00:00

abstract：:We made miniature modules filled with artificial oxygenator hollow fibers and conducted a simple experiment to study the effect of different membrane structures on the blood. Three types of modules were made: one filled with polyolefin, one filled with polypropylene, and a blank module. The 3 modules were connected th...

journal_title：Artificial organs

authors： Nishida H,Shibuya M,Endo M,Koyanagi H

更新日期：1996-12-01 00:00:00

abstract：:As the aortic valve (AV) opens, the pump pressure head remains constant, which is reflected as a "notch/plateau" in pump pressure and flow signals. However, instantaneous flow estimation may be influenced by friction and is particularly difficult in axial pumps. Therefore, a new method to determine the duration of AV ...

journal_title：Artificial organs

authors： Hayward C,Lim CP,Schima H,Macdonald P,Moscato F,Muthiah K,Granegger M

更新日期：2015-08-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB) is a nonphysiologic environment for an organism. The damage of blood components may also lead to organ dysfunction, some-times recognized as postperfusion syndrome. One possible way to diminish the risk of these complications would be to reduce the thorombogenicity and to improve the bioco...

journal_title：Artificial organs

authors： Horimoto H,Kondo K,Asada K,Sasaki S

更新日期：1996-08-01 00:00:00

abstract：:Late referral (LR) to dialysis therapy has been associated with poor outcomes in people with end-stage renal disease. This had been ascribed to the frequent use of temporary vascular catheters (TVCs) in LR patients. The effects of LR and TVC on the outcomes of an incident hemodialysis population (n = 101) were investi...

journal_title：Artificial organs

authors： Gonçalves EA,Andreoli MC,Watanabe R,Freitas MC,Pedrosa AC,Manfredi SR,Draibe SA,Cendoroglo M,Canziani ME

更新日期：2004-11-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB), an integral part of valve surgery, is known to cause hemodilution, which can lead to a need for blood transfusion as well as a systemic inflammatory reaction. Our aim was to evaluate a reduced priming (RP) system for CPB with regard to clinical outcomes in patients undergoing valve surger...

journal_title：Artificial organs

authors： Sato K,Namura O,Sogawa M,Shimada K,Tosaka Y,Hayashi J

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Ventricular assist devices are gaining ground in the therapeutic treatment of chronic heart failure. These devices are sometimes used as a bridge to recovery by unloading the left ventricle (LV) and restoring its function. It is therefore important to preserve the heart muscle and apply less invasive implant...

journal_title：Artificial organs

authors： Vandenberghe S,Nishida T,Segers P,Meyns B,Verdonck P

更新日期：2004-07-01 00:00:00

abstract：:Neurologic complications during on-pump cardiovascular surgery are often induced by mobilization of atherosclerotic plaques, which is directly related to enhanced wall shear stress. In the present study, we numerically evaluated the impact of dispersive aortic cannulas on aortic blood flow characteristics, with specia...

journal_title：Artificial organs

authors： Assmann A,Gül F,Benim AC,Joos F,Akhyari P,Lichtenberg A

更新日期：2015-03-01 00:00:00

abstract：:The trend in neural prostheses using selective nerve stimulation for electrical stimulation therapies is headed toward single-part systems having a large number of working electrodes (WEs), each of which selectively stimulate neural tissue or record neural response (NR). The present article reviews the electrochemical...

journal_title：Artificial organs

authors： Pečlin P,Mehle A,Karpe B,Rozman J

更新日期：2015-10-01 00:00:00

abstract：:Chronic kidney disease is increasing in both developed and emerging countries with progressive encroachment on health services budgets. In spite of the lack of accurate registries, we tried to focus on the magnitude of the problem on different continents. Prevention of progression has been a remote but reachable goal....

journal_title：Artificial organs

authors： Hafez MH,Abdellatif DA,Elkhatib MM

更新日期：2006-07-01 00:00:00

abstract：:Hypoalbuminemia, a strong predictor of morbidity and mortality in hemodialysis patients, can be a consequence of a combination of malnutrition and inflammatory reactions. The purpose of this study was to analyze serum albumin as a marker of nutritional status in maintenance hemodialysis patients with no signs of infla...

journal_title：Artificial organs

authors： Santos NS,Draibe SA,Kamimura MA,Canziani ME,Cendoroglo M,Júnior AG,Cuppari L

更新日期：2003-08-01 00:00:00

abstract：:Liposome-encapsulated hemoglobin (LEH) was proven to be protective in cerebral ischemia/reperfusion injury. The present study evaluated LEH in a rat model of permanent middle cerebral artery (MCA) occlusion to clarify its effect during ischemia and reperfusion. Five minutes after thread occlusion of the MCA, rats were...

journal_title：Artificial organs

authors： Kawaguchi AT,Kurita D,Furuya H,Yamano M,Ogata Y,Haida M

更新日期：2009-02-01 00:00:00

abstract：:Long-term hemodialysis catheter dwell time in the central vein predisposes to fibrin sheath development, which subsequently causes catheter malfunction or occlusion. In very rare cases, the catheter can be overgrown with fibrin and rigidly connected with the vein or heart structures. This makes its removal almost impo...

journal_title：Artificial organs

authors： Garcarek J,Gołębiowski T,Letachowicz K,Kusztal M,Szymczak M,Madziarska K,Jakuszko K,Zmonarski S,Guziński M,Weyde W,Klinger M

更新日期：2016-05-01 00:00:00

abstract：:The injurious effects of reactive oxygen species on venous tissues and the potential protective role played by green tea polyphenol (GTPP) on human saphenous veins were investigated. Oxidative stress was induced exogenously in the vein segments, either by adding 0.8 or 1.6 M of H2O2, or by using 80 or 160 U/L of xanth...

journal_title：Artificial organs

authors： Han DW,Suh H,Park YH,Cho BK,Hyon SH,Park JC

更新日期：2003-12-01 00:00:00

abstract：:The PI3K/Akt signaling pathway has been implicated in playing an important role in platelet activation during hemostasis and thrombosis involving platelet-matrix interaction and platelet aggregation. Its role in non-physiological shear stress (NPSS)-induced platelet activation relevant to high-shear blood contacting m...

journal_title：Artificial organs

authors： Chen Z,Li T,Kareem K,Tran D,Griffith BP,Wu ZJ

更新日期：2019-09-01 00:00:00

abstract：:There is an increasing need for research and development centers to deal with design and evaluation of organ replacement systems, the improvement of older devices, and the study of biocompatibility problems. Special attention, in this article, is focused on the determinant role of the background of the investigators i...

journal_title：Artificial organs

authors： Vanholder R,Ringoir S

更新日期：1989-12-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB) is required in some lung transplantation (LTx) operations. However, it increases risks of bleeding and early graft dysfunction. We report our experiences of replacing CPB with heparin-bound extracorporeal membrane oxygenation (ECMO) in LTx operations. If extracorporeal circulation was anti...

journal_title：Artificial organs

authors： Ko WJ,Chen YS,Lee YC

更新日期：2001-08-01 00:00:00

abstract：:The E4T is a totally implantable total artificial heart (TAH) resulting from many years of research work at the Cleveland Clinic Foundation (CCF) and Nimbus, Inc. It consists of four implanted subsystems: the pumping unit, the variable volume device, the transcutaneous transformer, and the internal battery. The pumpin...

journal_title：Artificial organs

authors： Smith WA,Hete BF,Kiraly RJ,Fujimoto LK,Jacobs GB,Ishikawa M,Butler K,Nosé Y

更新日期：1988-10-01 00:00:00

abstract：:A computer simulation was carried out to investigate the influence of nonpulsatile left ventricular assistance on hemodynamics. A simulation circuit was constructed to represent the circulatory system. A source of current was added to denote the nonpulsatile blood pump. The left and right ventricles were replaced by v...

journal_title：Artificial organs

authors： Mitsui N,Fukunaga S,Koura Y,Morita S,Hotei H,Sueshiro M,Sueda T,Matsuura Y

更新日期：1996-05-01 00:00:00

abstract：:Four hundred and forty-two serum ferritin determinations were performed in 144 patients on chronic intermittent hemodialysis treatment with intravenous iron substitution and/or oral iron substitution. Iron substitution should be done individually according to regular serum ferritin determinations. Intravenous iron sub...

journal_title：Artificial organs

authors： Müller HA,Schneider H,Hövelborn U,Streicher E

更新日期：1981-05-01 00:00:00

abstract：:Different methods are used, clinically and experimentally, to assist severely impaired heart function by means of skeletal muscle. The efficiency of these methods is restricted by skeletal muscle losing strength after transpositioning and during conditioning and not being sufficiently resistant to fatigue. This is mai...

journal_title：Artificial organs

authors： Lanmüller H,Sauermann S,Unger E,Schnetz G,Mayr W,Bijak M,Girsch W

更新日期：1999-04-01 00:00:00

abstract：:Temporary and immediately usable vascular access is a vital need in treating uremic patients. Subclavian vein cannulation, although a major progress, has been associated with significant morbidity and mortality. Accordingly, for the last 2.5 years the authors have been developing an alternative technique consisting of...

journal_title：Artificial organs

authors： Canaud B,Beraud JJ,Joyeux H,Mion C

更新日期：1986-10-01 00:00:00

abstract：:We studied 22 patients with residual pulmonary hypertension or symptoms of postoperative pulmonary hypertensive crisis. They received low-dose inhalation (10 ppm) of nitric oxide (NO), a selective pulmonary vasodilator, after total correction for congenital heart anomalies. Fifteen minutes of NO inhalation improved th...

journal_title：Artificial organs

authors： Matsui J,Yahagi N,Kumon K,Hayashi H,Watanabe Y,Haruna M,Tanigami H,Yagihara T,Takamoto S,Kamiya T

更新日期：1997-01-01 00:00:00

abstract：:The principle of a patient-specific immunoadsorber (PsIA) is demonstrated. Studies with model systems (HSA/anti-HSA) on immobilization, stability, and leakage form the basis for the presented fast-performance liquid chromatography (FPLC) and batch experiments, which were conducted using two different protein A adsorbe...

journal_title：Artificial organs

authors： Kunkel S,Holtz M,Grossjohann B,Schuett W,Klinkmann H,Kong D,Yamada R,Kimura H,Matic GB,Ramlow W,Boeden HF

更新日期：2002-02-01 00:00:00

abstract：:Growth factors and morphogens secreted by bone marrow mesenchymal stem cells (BMSCs) of bone marrow fluid may promote tooth regeneration. Accordingly, a tissue engineering approach was utilized to develop an economical strategy for obtaining the growth factors and morphogens from BMSCs. Unerupted second molar tooth bu...

journal_title：Artificial organs

authors： Kuo TF,Lin HC,Yang KC,Lin FH,Chen MH,Wu CC,Chang HH

更新日期：2011-02-01 00:00:00