Intestinal tissue oxygenation and tumor necrosis factor-alpha release during systemic blood flow changes in pigs with left ventricular assist devices.

abstract：:Microcapsules containing insulin crystals or islets of Langerhans were made by extruding a mixture of insulin crystals or islets and sodium alginate into a calcium chloride solution, and then coating it with poly-l-lysine. When these microcapsules were incubated at 37 degrees C, insulin could be detected readily in th...

journal_title：Artificial organs

authors： Leung YF,O'Shea GM,Goosen MF,Sun AM

更新日期：1983-05-01 00:00:00

abstract：:In a calf model, 3 standard and 3 heparin coated intraaortic balloons (IAB) were inserted and left deflated in the descending aorta during 20 min to simulate balloon rupture. At the end of the experiment, the IAB were examined, and 3 samples of each were collected for scanning electron microscopy (SEM) analysis. None ...

journal_title：Artificial organs

authors： Mueller XM,Tevaearai HT,Hayoz D,von Segesser LK

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:The use of ventricular assist devices (VAD) as a bridge to heart transplant (HT) is increasing, while HT volume remains stagnant. This may portend longer waiting times and an otherwise more competitive environment for all patients on the HT waiting list. METHODS:A retrospective analysis of patients who were...

journal_title：Artificial organs

authors： Han JJ,Elzayn H,Duda MM,Iyengar A,Acker AM,Patrick WL,Helmers M,Birati EY,Atluri P

更新日期：2020-10-01 00:00:00

abstract：:Capillary membrane filters are devices commonly used for plasmapheresis and recirculating detoxification systems, including plasmaseparation units. Besides clinical trials and case reports, research on plasmafiltration techniques is carried out using in vitro systems. Notably, such hemoperfused in vitro systems requir...

journal_title：Artificial organs

authors： Unger JK,Haltern C,Dohmen B,Rossaint R

更新日期：2003-07-01 00:00:00

abstract：:Porcine endogenous retrovirus (PERV) genomes are present in all pig cells. In this retrospective study, we assessed PERV infectivity in 28 patients treated with an extracorporeal bioartificial liver (HepatAssist system) that includes a membrane device containing porcine hepatocytes. All patients tested negative for PE...

journal_title：Artificial organs

authors： Pitkin Z,Mullon C

更新日期：1999-09-01 00:00:00

abstract：:The design criteria of an extracorporeal circuit suitable for pulsatile flow are quite different and more entangled than for steady flow. The time and costs of the design process could be reduced if mutual influences between the pulsatile pump and other extracorporeal devices were considered without experimental trial...

journal_title：Artificial organs

authors： Pennati G,Fiore GB,Laganà K,Fumero R

更新日期：2004-02-01 00:00:00

abstract：:Total hip arthroplasty (THA) can be achieved by using a cemented or noncemented prosthesis. Besides patient's age, weight, and other clinical signs, the evaluation of the quality of the bones is a crucial parameter on which orthopedic surgeons base the choice between cemented and noncemented THA. Although bone density...

journal_title：Artificial organs

authors： Gargiulo P,Pétursson T,Magnússon B,Bifulco P,Cesarelli M,Izzo GM,Magnúsdóttir G,Halldórsson G,Ludvigsdóttir GK,Tribel J,Jónsson H Jr

更新日期：2013-06-01 00:00:00

abstract：:Recently, there has been an increase in the use of rat models of cardiopulmonary bypass (CPB) for research purposes. Much of this work has focused on cerebral injury associated with CPB. Many of these studies employ a peripheral cannulation approach, often utilizing the caudal artery and internal or external jugular v...

journal_title：Artificial organs

authors： Gourlay T,Modine T

更新日期：2010-06-01 00:00:00

abstract：:The E4T is a totally implantable total artificial heart (TAH) resulting from many years of research work at the Cleveland Clinic Foundation (CCF) and Nimbus, Inc. It consists of four implanted subsystems: the pumping unit, the variable volume device, the transcutaneous transformer, and the internal battery. The pumpin...

journal_title：Artificial organs

authors： Smith WA,Hete BF,Kiraly RJ,Fujimoto LK,Jacobs GB,Ishikawa M,Butler K,Nosé Y

更新日期：1988-10-01 00:00:00

abstract：:We assessed the relationship of certain clinical variables (including bradykinin [BK] release and dialysis membrane) to initial mean arterial pressure (MAP) reduction in 47 patients requiring continuous renal replacement therapy (CRRT) in an intensive care unit. The pretreatment MAP was 84 +/- 14 mm Hg for the group a...

journal_title：Artificial organs

authors： Stoves J,Goode NP,Visvanathan R,Jones CH,Shires M,Will EJ,Davison AM

更新日期：2001-12-01 00:00:00

abstract：:In order to define physiological properties of the autograft root, magnetic resonance imaging (MRI) findings relative to three different operative techniques were compared with those of control subjects. Twenty-three patients, 18/5 M/F, aged 32 ± 9 years, underwent MRI assessment of the aortic root. Patients with norm...

journal_title：Artificial organs

authors： Luciani GB,Viscardi F,Puppini G,Faggian G,Mazzucco A

更新日期：2011-12-01 00:00:00

abstract：:The rotational axis of the centrifugal pump has some associated problems such as blood destruction and sealing between the axis and pump housing. To improve upon these deficits we have developed a new type of blood pump, the magnetic rotary pump (MRP). The MRP has an original design with no rotational axis and no impe...

journal_title：Artificial organs

authors： Naganuma S,Yambe T,Sonobe T,Kobayashi S,Nitta S

更新日期：1997-07-01 00:00:00

abstract：:The abdominal left ventricular assist device (ALVAD) is an order of magnitude more effective than conventional intra-aortic balloon pumping (IABP) in unloading and providing circulatory support to the failing left ventricle. This is a report of a unique case which demonstrates that in the absence of pulmonary vascular...

journal_title：Artificial organs

authors： Norman JC,Dacso CC,Reul GJ,Massin EK,Klima T,Kahan BD,Keiser JT,Cooley DA

更新日期：1978-11-01 00:00:00

abstract：:Clinically, the percutaneous transcatheter aortic valve (TAV) has been reported to be deformed in a noncircular configuration after its implant. The deformation is universal and various, and it leads to serious leakage and durability problems. Even in the same deformation, the leaflets made in different tissue thickne...

journal_title：Artificial organs

authors： Feng W,Yang X,Liu Y,Fan Y

更新日期：2017-08-01 00:00:00

abstract：:A surgical method for the implantation of a mechanical right ventricular assist device which avoids resternotomy/thoracotomy and related complications at the time of explantation is presented. In order to support the failing right heart, a Dacron vascular graft was sewn to the pulmonary artery. For venous drainage, a ...

journal_title：Artificial organs

authors： Schopka S,Haneya A,Rupprecht L,Camboni D,Schmid C,Hilker M

更新日期：2012-08-01 00:00:00

abstract：:We investigated biodegradation and biocompatibility of poly(organophosphazenes). We prepared poly(organophosphazenes) having different side chain groups. The blood compatibility of poly(organophosphazenes) containing fluorinated side groups, poly(bis[trifluoroethoxy]phosphazene) (PbFP) and poly([trifluoroethoxy][ethyl...

journal_title：Artificial organs

authors： Kawakami H,Kanezaki S,Sudo M,Kanno M,Nagaoka S,Kubota S

更新日期：2002-10-01 00:00:00

abstract：:In a controlled European multicenter study, clinical tolerance of subcutaneously administered recombinant human erythropoietin (rh-EPO) therapy and its influence on the course of illness in 362 hemodialyzed patients (162 males, 200 females) from 16 European dialysis centers was studied. Of these, 181 patients served a...

journal_title：Artificial organs

authors： Klinkmann H,Wieczorek L,Scigalla P

更新日期：1993-04-01 00:00:00

abstract：:Coil-type silicone membrane oxygenators can only be used with roller blood pumps due to the resistance from the high blood flow. Therefore, during extracorporeal membrane oxygenation (ECMO) treatment, the combination of a roller pump and an oxygenator with a high blood flow resistance will induce severe hemolysis, whi...

journal_title：Artificial organs

authors： Motomura T,Maeda T,Kawahito S,Matsui T,Ichikawa S,Ishitoya H,Kawamura M,Nishimura I,Shinohara T,Oestmann D,Glueck J,Kawaguchi Y,Sato K,Nosé Y

更新日期：2002-11-01 00:00:00

abstract：:In bioartificial pancreatic systems, isolated islets of Langerhans are protected against immune rejection by an artificial membrane, permeable to glucose and insulin, but not to immunoglobulins and lymphocytes. Some of these devices, referred to as vascular systems, are set up to be connected to a vascular site in the...

journal_title：Artificial organs

authors： Lepeintre J,Briandet H,Moussy F,Chicheportiche D,Darquy S,Rouchette J,Imbaud P,Duron JJ,Reach G

更新日期：1990-02-01 00:00:00

abstract：:A woven fabric graft made of ultrafine polyester fibers (UFPF) (Toray Graft, water porosity: 100 ml/min/cm2:120 mm Hg H2O) was clinically applied in 81 cases (28 thoracic aortic aneurysms, 6 thoracoabdominal aortic aneurysms, 42 abdominal aortic aneurysms, and 5 atherosclerotic obstructions of the peripheral arteries)...

journal_title：Artificial organs

authors： Satoh S,Niu S,Kanda K,Hirai J,Nakazima S,Wada Y,Oka T,Noishiki Y

更新日期：1995-01-01 00:00:00

abstract：:The presence in rat serum of three novel immunosuppressive proteins is associated with induction of tolerance after liver grafting. One of these, KX-5 (40 kilodalton molecular weight) is present 40-100 days after grafting of DA liver into PVG, a combination in which liver grafts are not rejected; two others, KX-2 (87 ...

journal_title：Artificial organs

authors： Kamada N

更新日期：1996-10-01 00:00:00

abstract：:The kinetic features of ultrafiltration of cellulose dialysis membrane stored under various humidity and temperature conditions were studied to obtain basic information of shelf-life characteristics of dialyzers. The ultrafiltration rate (UFR) decreased with time and the UFR-time curve suggested that the UFR would app...

journal_title：Artificial organs

authors： Sato H,Kidaka T

更新日期：1981-08-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB), an integral part of valve surgery, is known to cause hemodilution, which can lead to a need for blood transfusion as well as a systemic inflammatory reaction. Our aim was to evaluate a reduced priming (RP) system for CPB with regard to clinical outcomes in patients undergoing valve surger...

journal_title：Artificial organs

authors： Sato K,Namura O,Sogawa M,Shimada K,Tosaka Y,Hayashi J

更新日期：2006-08-01 00:00:00

abstract：:Postoperative liver failure remains a major cause of morbidity and mortality after extensive hepatectomies. This study aims to evaluate the effectiveness of a hepatocyte bioreactor in the treatment of experimental post-hepatectomy liver failure. Our experimental model included a combination of a side-to-side portacava...

journal_title：Artificial organs

authors： Arkadopoulos N,Kostopanagiotou G,Nastos C,Papalois A,Papoutsidakis N,Kalimeris K,Defterevos G,Kanna T,Polyzois K,Kampouroglou G,Kypriotis D,Costopanagiotou C,Pafiti A,Tzanatos H,Smyrniotis V

更新日期：2011-01-01 00:00:00

abstract：:The purpose was to evaluate the cytotoxicity of two novel formulations (alpha and beta) of calcium phosphate cements. Positive control, represented by a commercial hydroxyapatite cement, and negative control were included for comparative purposes. A continuous lineage of fibroblastic cells was used, and the effect of ...

journal_title：Artificial organs

authors： Rossa C Jr,Marcantonio E Jr,Santos LA,Boschi AO,Raddi MS

更新日期：2005-02-01 00:00:00

abstract：:The Fas molecule, also designated APO-1/CD95, belongs to the tumor necrosis factor (TNF) receptor family. It is a widely expressed membrane-anchored protein that induces apoptosis by Fas/Fas ligand (Fas-L) mediation. It was reported that Fas-mediated apoptosis plays an important role in regulation of the immune system...

journal_title：Artificial organs

authors： Kawahito K,Misawa Y,Fuse K

更新日期：2000-08-01 00:00:00

abstract：:Centrifugal pumps are generally employed as nonpulsatile blood flow pumps; however, these pumps can produce pulsatile flow by periodically alternating the impeller rotation speed. This study investigates blood trauma due to the effect of pulse frequency and various ranges of pump speed. The hemolysis tests were conduc...

journal_title：Artificial organs

authors： Tayama E,Niimi Y,Takami Y,Ohashi Y,Ohtsuka G,Glueck JA,Mueller J,Nosé Y

更新日期：1997-12-01 00:00:00

abstract：:Although it is now understood that trained skeletal muscle can generate enough steady-state power to provide significant circulatory support, there are currently no means by which to tap this endogenous energy source to aid the failing heart. To that end, an implantable muscle energy converter (MEC) has been construct...

journal_title：Artificial organs

authors： Trumble DR,Melvin DB,Byrne MT,Magovern JA

更新日期：2005-09-01 00:00:00

abstract：:This paper describes a new miniaturized implantable bladder controller that is composed of 4 main parts: a volume monitoring device based on the tomography approach, a fully programmable miniaturized central processor and stimulator, a bidirectional data and power link, and an external controller. The proposed system ...

journal_title：Artificial organs

authors： Sawan M,Arabi K,Provost B

更新日期：1997-03-01 00:00:00

abstract：:Multiple observational studies along with a limited number of randomized clinical trials suggest that intensive hemodialysis (IHD) not only improves outcomes for uremic patients undergoing chronic dialysis but does so with a more favorable cost/benefit ratio compared with conventional hemodialysis. As a result of this...

journal_title：Artificial organs

authors： Naso A,Scaparrotta G,Naso E,Calò LA

更新日期：2015-09-01 00:00:00