Extracorporeal membrane oxygenator compatible with centrifugal blood pumps.

Abstract:

:Coil-type silicone membrane oxygenators can only be used with roller blood pumps due to the resistance from the high blood flow. Therefore, during extracorporeal membrane oxygenation (ECMO) treatment, the combination of a roller pump and an oxygenator with a high blood flow resistance will induce severe hemolysis, which is a serious problem. A silicone rubber, hollow fiber membrane oxygenator that has a low blood flow resistance was developed and evaluated with centrifugal pumps. During in vitro tests, sufficient gas transfer was demonstrated with a blood flow less than 3 L/min. Blood flow resistance was 18 mm Hg at 1 L/min blood flow. This oxygenator module was combined with the Gyro C1E3 (Kyocera, Japan), and veno-arterial ECMO was established on a Dexter strain calf. An ex vivo experiment was performed for 3 days with stable gas performance and low blood flow resistance. The combination of this oxygenator and centrifugal pump may be advantageous to enhance biocompatibility and have less blood trauma characteristics.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Motomura T,Maeda T,Kawahito S,Matsui T,Ichikawa S,Ishitoya H,Kawamura M,Nishimura I,Shinohara T,Oestmann D,Glueck J,Kawaguchi Y,Sato K,Nosé Y

doi

10.1046/j.1525-1594.2002.07117.x

subject

Has Abstract

pub_date

2002-11-01 00:00:00

pages

952-8

issue

11

eissn

0160-564X

issn

1525-1594

pii

aor7117

journal_volume

26

pub_type

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