Abstract:
:To develop a method for making percutaneous devices that have high biocompatibility and do not induce downgrowth of epidermal cells, we prepared a partial decellularized dermis (DD)/poly(methyl methacrylate) (PMMA) complex (PDPC) with a PMMA rod firmly stabilized inside. The porcine decellularized tissue was chosen because of its high biocompatibility and mechanical properties, and MMA was used because it would adhere firmly to a polymer such as a catheter. The MMA filled the cavities in the dermis and polymerized, anchoring to the collagenous fibrils inside the porcine DD. The PDPC was cemented to the PMMA rod tightly and it was integrated with the surrounding tissue within 12 weeks of implantation. Furthermore, no downgrowth of the epidermis, which may cause clinical problems, was observed. We consider that the tissue-polymer complex may be a suitable candidate for use in percutaneous devices.
journal_name
Artif Organsjournal_title
Artificial organsauthors
Nam K,Matsushima R,Kimura T,Fujisato T,Kishida Adoi
10.1111/aor.12330subject
Has Abstractpub_date
2014-12-01 00:00:00pages
1060-5issue
12eissn
0160-564Xissn
1525-1594journal_volume
38pub_type
杂志文章abstract::Patients with kidney failure can only survive with some form of kidney replacement (transplant or dialysis). Unfortunately, innovations in kidney replacement therapy lag behind many other medical fields. This study compiles expert opinions on candidate technologies for future kidney replacement therapies. A worldwide ...
journal_title:Artificial organs
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journal_title:Artificial organs
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.13833
更新日期:2020-10-01 00:00:00
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journal_title:Artificial organs
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更新日期:1985-05-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1984.tb04248.x
更新日期:1984-02-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/aor.12000
更新日期:2013-04-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
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更新日期:1998-06-01 00:00:00
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pub_type: 杂志文章
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更新日期:2012-05-01 00:00:00
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更新日期:2011-04-01 00:00:00
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pub_type: 杂志文章
doi:10.1111/j.1525-1594.1982.tb01675.x
更新日期:1982-08-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.2008.00633.x
更新日期:2008-10-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1046/j.1525-1594.1999.06445.x
更新日期:1999-11-01 00:00:00
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doi:10.1046/j.1525-1594.2000.06551.x
更新日期:2000-10-01 00:00:00
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更新日期:2010-12-01 00:00:00
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journal_title:Artificial organs
pub_type: 临床试验,杂志文章
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更新日期:1990-12-01 00:00:00
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journal_title:Artificial organs
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更新日期:1997-09-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2018-08-01 00:00:00
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更新日期:2000-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1046/j.1525-1594.2001.06907.x
更新日期:2001-11-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
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更新日期:1978-08-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
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更新日期:1997-04-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
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更新日期:1984-11-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1988.tb02747.x
更新日期:1988-04-01 00:00:00
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journal_title:Artificial organs
pub_type: 杂志文章
doi:10.1111/j.1525-1594.1987.tb02622.x
更新日期:1987-02-01 00:00:00