Computational fluid dynamics prediction of blood damage in a centrifugal pump.

abstract：:The weight gain of IVOX devices removed from the first 49 human clinical trials patients after from 1 to 29 days of implantation into the venae caval blood stream has been assessed. Each patient had received sufficient systemic heparin to maintain activated clotting times between 150 and 200 s while the IVOX device wa...

journal_title：Artificial organs

authors： Imai H,Schaap RN,Mortensen JD

更新日期：1994-11-01 00:00:00

abstract：:We assessed the relationship of certain clinical variables (including bradykinin [BK] release and dialysis membrane) to initial mean arterial pressure (MAP) reduction in 47 patients requiring continuous renal replacement therapy (CRRT) in an intensive care unit. The pretreatment MAP was 84 +/- 14 mm Hg for the group a...

journal_title：Artificial organs

authors： Stoves J,Goode NP,Visvanathan R,Jones CH,Shires M,Will EJ,Davison AM

更新日期：2001-12-01 00:00:00

abstract：:Pyridoxalated-hemoglobin-polyoxyethylene conjugate (PHP), which is made from out-dated human red blood cells by two major chemical modifications, namely pyridoxalation and conjugation with polyoxyethylene (POE), is currently under development as a physiological oxygen carrier. This study assessed the effects of PHP-88...

journal_title：Artificial organs

authors： Takahashi T,Iwasaki K,Malchesky PS,Harasaki H,Matsushita M,Nosé Y,Rolin H 3rd,Hall PM

更新日期：1993-03-01 00:00:00

abstract：:Using urea and inulin as markers, we have developed a simple method to calculate intracellular and extracellular fluid volume in patients before and after hemofiltration therapy. During conventional hemofiltration using substitution fluid with a Na+ concentration of 140 mEq/L, a decrease in extracellular fluid volume ...

journal_title：Artificial organs

authors： Kimura G,Satani M,Kojima S,Kuroda K,Itoh K,Ikeda M

更新日期：1982-02-01 00:00:00

abstract：:As a preliminary investigation to establish a cryopreservation method suited for bioartificial livers (BALs), three-dimensional (3-D) cryopreservation experiments with fibroblasts were performed, in which the cells were firstly seeded into a porous scaffold, and the scaffold containing the cells was then cryopreserved...

journal_title：Artificial organs

authors： Miyoshi H,Ehashi T,Ohshima N,Jagawa A

更新日期：2010-07-01 00:00:00

abstract：:Mechanical circulatory support (MCS) devices continue to be hampered by thrombotic adverse events (AEs), a consequence of device-imparted supraphysiologic shear stresses, leading to shear-mediated platelet activation (SMPA). In advancing MCS devices from design to clinical use, in vitro circulatory loops containing th...

journal_title：Artificial organs

authors： Li M,Walk R,Roka-Moiia Y,Sheriff J,Bluestein D,Barth EJ,Slepian MJ

更新日期：2020-06-01 00:00:00

abstract：:The aim of this meta-analysis was to determine whether pulsatile perfusion during cardiac surgery has a lesser effect on renal dysfunction than nonpulsatile perfusion after cardiac surgery in randomized controlled trials. MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials were used to identify ava...

journal_title：Artificial organs

authors： Nam MJ,Lim CH,Kim HJ,Kim YH,Choi H,Son HS,Lim HJ,Sun K

更新日期：2015-09-01 00:00:00

abstract：:The aim of the study is to measure the volume of homologous blood needed for one pediatric patient during his hospital stay. Over a 4-month period, all the patients operated upon with a blood prime or requiring blood transfusion during their hospital stay were included in this study.The cardiopulmonary bypass protocol...

journal_title：Artificial organs

authors： Durandy Y

更新日期：2010-11-01 00:00:00

abstract：:A centrifugal blood pump with a double pivot impeller and an eccentric inlet port is being developed as an implantable artificial heart by the Baylor College of Medicine and Miwatec Co. Ltd. Flow visualization measurements were conducted to compare the flow around the pivot for two impeller operational modes: the top ...

journal_title：Artificial organs

authors： Yamane T,Kodama T,Nishida M,Maruyama O,Yamamoto Y,Shinohara T,Motomura T,Nosé Y

更新日期：2006-01-01 00:00:00

abstract：:The aim of this study was to verify if dialysis solution volumes used in patients on continuous ambulatory peritoneal dialysis (CAPD) interfere with pulmonary function and if the pulmonary volumes interfere with the lymphatic absorption of the peritoneal cavity. We submitted 10 CAPD patients with a mean age of 48 +/- ...

journal_title：Artificial organs

authors： Marmanillo CG,Pecoits-Filho RF,Romão JE Jr,Kakehashi ET,Sabbaga E,Marcondes M,Abensur H

更新日期：2001-11-01 00:00:00

abstract：:Medial opening-wedge has gained popularity in comparison to other techniques of high tibial osteotomy. This technique involves the creation of a gap in the tibia. Filling the gap with autologous iliac bone graft was recommended in the classic description, to prevent complications such as correction loss or delayed bon...

journal_title：Artificial organs

authors： Zorzi AR,da Silva HG,Muszkat C,Marques LC,Cliquet A Jr,de Miranda JB

更新日期：2011-03-01 00:00:00

abstract：:Improvements in implantable ventricular assist device (VAD) performance will be required to obtain patient outcomes that are comparable with those of heart transplantation. The HeartQuest VAD (WorldHeart, Oakland, CA, U.S.A.) is an advanced device, with full magnetic suspension of the rotor, designed to address specif...

journal_title：Artificial organs

authors： Bearnson GB,Jacobs GB,Kirk J,Khanwilkar PS,Nelson KE,Long JW

更新日期：2006-05-01 00:00:00

abstract：:Extracorporeal human lymphatic organs are expected to be excellent tools in the study of human molecular and cellular bases of the immunologic balance and tissue harmony. A rational approach and process to design a device and a procedure to recreate the human lymph node environment in vitro is described with emphasis ...

journal_title：Artificial organs

authors： Giese C,Demmler CD,Ammer R,Hartmann S,Lubitz A,Miller L,Müller R,Marx U

更新日期：2006-10-01 00:00:00

abstract：:Thirteen percent of 99 patients undergoing maintenance hemodialysis showed an increased predialysis peripheral blood eosinophil count (mean value of 828 cells/mm3, range 410-2,710). Patients with eosinophilia were predominantly male and evidenced more frequent elevation of total plasma IgE levels. Otherwise, no differ...

journal_title：Artificial organs

authors： Friedberg M,Joffe P,Nielsen B,Nielsen LP

更新日期：1987-04-01 00:00:00

abstract：:Roller pumps have been widely used in the ventricular assist field for many years, while the significant hemolysis caused by its mechanical stress is still a fundamental problem. Although the usual under-occlusion setting was considered as an effective method to reduce the hemolysis rate, its nonocclusive condition of...

journal_title：Artificial organs

authors： Zhou Y,Sun B,Chen M,Cui C

更新日期：2020-07-31 00:00:00

abstract：:Stimulation of different spinal cord segments in humans is a widely developed clinical practice for modification of pain, altered sensation, and movement. The human lumbar cord has become a target for modification of motor control by epidural and, more recently, by transcutaneous spinal cord stimulation. Posterior col...

journal_title：Artificial organs

authors： Danner SM,Hofstoetter US,Ladenbauer J,Rattay F,Minassian K

更新日期：2011-03-01 00:00:00

abstract：:The aim of this study is to evaluate the effect of temperature on cerebral oxygen metabolism at total body flow bypass and antegrade cerebral perfusion (ACP). Neonatal piglets were put on cardiopulmonary bypass (CPB) with the initial flow rate of 200mL/kg/min. After cooling to 18°C (n=6) or 25°C (n=7), flow was reduce...

journal_title：Artificial organs

authors： Sasaki T,Boni L,Riemer RK,Yeung JT,Ramamoorthy C,Beckman R,Gisner C,Shuttleworth P,Hanley FL,Reddy VM

更新日期：2010-11-01 00:00:00

abstract：:Continuous-flow left ventricular assist devices (LVADs) reduce peak systolic flow, increase diastolic flow, and eliminate pulsatility of circulation. Altered blood flow may lead to a change in end-organ perfusion. Analysis of the flow dynamics of the arteries of end organs, such as the brain, may indicate whether an o...

journal_title：Artificial organs

authors： Karahan M,Kocabeyoglu SS,Kervan U,Sert DE,Aygun E,Tola M,Demirkan B,Mungan S,Kursun O,Catav Z,Pac M

更新日期：2020-05-01 00:00:00

abstract：:To evaluate the potential clinical usefulness of a modified hemoglobin, pyridoxalated hemoglobin polyoxyethylene conjugate (PHP), the hindlimb vascular bed was perfused with PHP solution while monitoring tissue oxygen tension (PtO2) in anesthetized dogs. The hindlimb region was perfused through the external iliac arte...

journal_title：Artificial organs

authors： Kida Y,Yamakawa T,Iwasaki S,Furusho N,Kadowaki Y,Iwata S,Iwashita Y,Nishi K

更新日期：1995-06-01 00:00:00

abstract：:Postoperative liver failure remains a major cause of morbidity and mortality after extensive hepatectomies. This study aims to evaluate the effectiveness of a hepatocyte bioreactor in the treatment of experimental post-hepatectomy liver failure. Our experimental model included a combination of a side-to-side portacava...

journal_title：Artificial organs

authors： Arkadopoulos N,Kostopanagiotou G,Nastos C,Papalois A,Papoutsidakis N,Kalimeris K,Defterevos G,Kanna T,Polyzois K,Kampouroglou G,Kypriotis D,Costopanagiotou C,Pafiti A,Tzanatos H,Smyrniotis V

更新日期：2011-01-01 00:00:00

abstract：:The objective of our study was to investigate chondrogenesis potential of human adipose-derived mesenchymal stromal cells (MSCs), using as a positive control a human source of cartilage-derived progenitor cells (PCs). This source of PCs was recently described by our group and dwells on the surface of nasoseptal cartil...

journal_title：Artificial organs

authors： Baptista LS,Silva KR,Pedrosa CS,Amaral RJ,Belizário JV,Borojevic R,Granjeiro JM

更新日期：2013-12-01 00:00:00

abstract：:One hundred eighty-eight Mitroflow pericardial valves, implanted on 166 patients from March 1983 to December 1986, have been followed for a total of 4316 patients x months. Mortality rate in the first three postoperative months is approximately 10% related to noncardiac complications. One hundred forty-nine patients a...

journal_title：Artificial organs

authors： Loisance D,Hillion ML,Cachera JP

更新日期：1988-08-01 00:00:00

abstract：:By using high speed gel filtration combined with ion exchange gradient elution chromatography, the concentrations of plasma (p) middle molecules (MM) were determined in 126 samples from 90 non-dialyzed azotemic patients and in 210 pre-dialysis samples from 53 regular hemodialysis and 24 intermittent peritoneal dialysi...

journal_title：Artificial organs

authors： Asaba H,Bergström J,Fürst P,Johnson C,Yahiel V

更新日期：1981-01-01 00:00:00

abstract：:We aimed to determine the effect of elective left heart decompression at the time of initiation of central venoarterial extracorporeal membrane oxygenation (VA ECMO) on VA ECMO duration and clinical outcomes in children in a single tertiary ECMO referral center with a large pediatric population from a national referra...

journal_title：Artificial organs

authors： Hacking DF,Best D,d'Udekem Y,Brizard CP,Konstantinov IE,Millar J,Butt W

更新日期：2015-04-01 00:00:00

abstract：:Tissue-engineered heart valves constructed from a xenogeneic or allogeneic decellularized matrix might overcome the disadvantages of current heart valve substitutes. One major necessity besides effective decellularization is to preserve the biomechanical properties of the valve. Native and decellularized porcine pulmo...

journal_title：Artificial organs

authors： Seebacher G,Grasl C,Stoiber M,Rieder E,Kasimir MT,Dunkler D,Simon P,Weigel G,Schima H

更新日期：2008-01-01 00:00:00

abstract：:Transcatheter aortic valve implantation (TAVI) has gained considerable acceptance in the past decade due to its lower risks than conventional open-heart surgery. However, the deformation and delamination of the leaflets during the crimping procedure have raised questions about the durability and long-term serviceabili...

journal_title：Artificial organs

authors： Mao J,Rassoli A,Tong Y,Rouse EN,Le-Bel G,How D,Germain L,Fatouraee N,Zhang Z,Reed RR,Guidoin R

更新日期：2019-10-01 00:00:00

abstract：:We have made an eccentric roller type total artificial heart (ERTAH). The ERTAH is a positive-displacement device comparable to a DeBakey roller pump. Its left and right outputs are determined by the size of its blood chambers, and the ratio of its left and right output is almost constant. We focused on an interatrial...

journal_title：Artificial organs

authors： Wada H,Fukunaga S,Watari M,Sakai H,Sugawara Y,Ochikubo H,Imai K,Shibamura H,Orihashi K,Sueda T,Matsuura Y

更新日期：1999-08-01 00:00:00

abstract：:Molecular biology has been moving swiftly toward clarifying the entire genome of organisms, including human. The human genome efforts that promote this transaction are characterized by the large-scale, high throughput production of data about the structure of the genome of the molecular level and its computer-assisted...

journal_title：Artificial organs

authors： Matsubara K

更新日期：1996-08-01 00:00:00

abstract：:Modular hip prostheses are commonly used today. Dedicated surgical auxiliary instrumentation is indispensable. A correct coupling between the prosthesis and the instrument is necessary to avoid damage. Based on a specific commercial design (AnCAFit, Wright Cremascoli Ortho, Toulon, France), the aim of this work was to...

journal_title：Artificial organs

authors： Varini E,Cristofolini L,Viceconti M,Traina F

更新日期：2006-07-01 00:00:00

abstract：:Tubular polymer scaffolds based on tissue engineering techniques have been studied as potential alternatives for vascular regeneration implants. The blood vessels of the cardiovascular system are mainly fibrous, composed of collagen (Col) and elastin (El), and its inner layer consists of endothelial cells. In this wor...

journal_title：Artificial organs

authors： Rodrigues ICP,Pereira KD,Woigt LF,Jardini AL,Luchessi AD,Lopes ÉSN,Webster TJ,Gabriel LP

更新日期：2020-11-10 00:00:00