Development of high-efficiency molecular adsorbent recirculating system: preliminary report.

abstract：:The new Advanced ventricular assist device (Advanced VAD) has many features such as improving pulsatility and preventing regurgitant flow during pump stoppage. The purpose of this study was to evaluate the effects of design modifications of the Advanced VAD on these features in vitro. Bench testing of four versions of...

journal_title：Artificial organs

authors： Miyamoto T,Byram N,Karimov JH,Adams J,Dessoffy R,Kuban BD,Gao S,Horvath DJ,Fukamachi K

更新日期：2019-10-01 00:00:00

abstract：:We reported previously that Lixelle, which was used for beta-2 microglobulin (BMG) adsorption columns, could adsorb not only BMG but also inflammatory cytokines. We then were interested in the application of Lixelle to patients with systemic inflammatory response syndrome (SIRS) and tried to find out its ability to ad...

journal_title：Artificial organs

authors： Tsuchida K,Takemoto Y,Nakatani T,Nakamura T,Sugimura K,Yamamoto K

更新日期：2000-07-01 00:00:00

abstract：:We aimed to investigate whether acellular endocardium can be used as a useful biomaterial for the intima of engineered small-caliber vascular grafts. Fresh endocardium was harvested from the swine left atrium and was decellularized by digestion with the decellularization solution of Triton X-100 and SDS containing DNa...

journal_title：Artificial organs

authors： Wang F,Guan X,Wu T,Qiao J,Han Z,Wu J,Yu X,You Q

更新日期：2016-12-01 00:00:00

abstract：:Cybernetics-based concepts can allow for complete independence for paralyzed individuals, including sensory motor recovery. Spinal cord injuries are responsible for a huge stress on health and a financial burden to society. This article focuses on novel procedures such as functional diagnosis for paraplegics and tetra...

journal_title：Artificial organs

authors： Varoto R,Cliquet A Jr

更新日期：2015-10-01 00:00:00

abstract：:Out-of-Hospital refractory Cardiac Arrest (OHrCA) has a mortality rate between 90 and 95%. Since 2009, French medical academic societies have recommended the use of extracorporeal life support (ECLS) for OHrCA. According to these guidelines, patients were eligible for ECLS support if vital signs were still present dur...

journal_title：Artificial organs

authors： Rousse N,Robin E,Juthier F,Hysi I,Banfi C,Al Ibrahim M,Coadou H,Goldstein P,Wiel E,Vincentelli A

更新日期：2016-09-01 00:00:00

abstract：:Spiral/helical forms of blood flow have been observed in large arteries of the cardiovascular system, but their benefits remain underappreciated. Spiral flow has been postulated to improve near-wall washout, promoting anti-atherothrombotic conditions. This research aims to study the washout characteristics of spiral f...

journal_title：Artificial organs

authors： Huang Zhang P,Tkatch C,Newman R,Grimme W,Vainchtein D,Kresh JY

更新日期：2019-12-01 00:00:00

abstract：:This study evaluated the usefulness of the three-dimensional representation of electrocardiogram traces (3DECG) to reveal acute and gradual changes during a full session of hemodiafiltration (HDF) in end-stage renal disease (ESRD) patients. Fifteen ESRD patients were included (six men, nine women, age 46 ± 19 years ol...

journal_title：Artificial organs

authors： Rodriguez-Fernandez R,Infante O,Perez-Grovas H,Hernandez E,Ruiz-Palacios P,Franco M,Lerma C

更新日期：2012-06-01 00:00:00

abstract：:We recently experienced a case of a female hemodialysis patient with multiple intestinal angiodysplasias. In 2001, she complained of melena, and angiographic embolization halted bleeding from ileum angiodysplasia. In 2002, she again complained of black stool. Abdominal angiography found jejunum angiodysplasia, and pha...

journal_title：Artificial organs

authors： Takenaka T,Kanno Y,Suzuki H

更新日期：2005-01-01 00:00:00

abstract：:Chitosan posttreatment has been shown to be effective in prevention of calcification of the glutaraldehyde treated bovine pericardium when implanted subdermally in rats for 12 weeks. The efficacy of chitosan posttreatment in complete calcium mitigation of the glutaraldehyde treated porcine aortic valves implanted in t...

journal_title：Artificial organs

authors： Chanda J,Kuribayashi R,Abe T,Sekine S,Shibata Y,Yamagishi I

更新日期：1997-05-01 00:00:00

abstract：:The neutralization of bacterial endotoxins (ET) is still an unsolved problem in therapeutic medicine. The efficacy of anti-endotoxin antibodies or receptor antagonists and other substances interfering with the endotoxin-induced pathomechanisms is dependent on an intact cellular degradation system of the host. However,...

journal_title：Artificial organs

authors： Mitzner S,Schneidewind J,Falkenhagen D,Loth F,Klinkmann H

更新日期：1993-09-01 00:00:00

abstract：:Doppler ultrasound is a noninvasive technique for monitoring moving objects such as flowing blood while ignoring stationary objects such as shunt tubing. A Doppler system was investigated to determine its sensitivity in detecting particulate release in blood during hemodialysis. Seven hemodialysis procedures with dogs...

journal_title：Artificial organs

authors： Badylak SF,Ash SR,Thornhill JA,Carr DJ

更新日期：1984-05-01 00:00:00

abstract：:This article introduces a unique miniaturization process of a magnetically levitated axial flow blood pump from a functional prototype to a pump suitable for animal trials. Through COMSOL three-dimensional finite element analysis and experimental verification, the hybrid magnetic bearings of the pump have been miniatu...

journal_title：Artificial organs

authors： Cheng S,Olles MW,Olsen DB,Joyce LD,Day SW

更新日期：2010-10-01 00:00:00

abstract：:We investigated biodegradation and biocompatibility of poly(organophosphazenes). We prepared poly(organophosphazenes) having different side chain groups. The blood compatibility of poly(organophosphazenes) containing fluorinated side groups, poly(bis[trifluoroethoxy]phosphazene) (PbFP) and poly([trifluoroethoxy][ethyl...

journal_title：Artificial organs

authors： Kawakami H,Kanezaki S,Sudo M,Kanno M,Nagaoka S,Kubota S

更新日期：2002-10-01 00:00:00

abstract：:The aim of the study is to measure the volume of homologous blood needed for one pediatric patient during his hospital stay. Over a 4-month period, all the patients operated upon with a blood prime or requiring blood transfusion during their hospital stay were included in this study.The cardiopulmonary bypass protocol...

journal_title：Artificial organs

authors： Durandy Y

更新日期：2010-11-01 00:00:00

abstract：:Growth factors and morphogens secreted by bone marrow mesenchymal stem cells (BMSCs) of bone marrow fluid may promote tooth regeneration. Accordingly, a tissue engineering approach was utilized to develop an economical strategy for obtaining the growth factors and morphogens from BMSCs. Unerupted second molar tooth bu...

journal_title：Artificial organs

authors： Kuo TF,Lin HC,Yang KC,Lin FH,Chen MH,Wu CC,Chang HH

更新日期：2011-02-01 00:00:00

abstract：:The effects of Fluosol-DA 20% on circulating blood cells, hemodynamic parameters, blood gases, and organs are described and compared with the results of phase I human studies and animal experiments. Bleeding of preoperative anemia and/or surgical bleeding, Fluosol-DA 20% was administered to 7 of 10 Jehovah's Witness p...

journal_title：Artificial organs

authors： Ohyanagi H,Nakaya S,Okumura S,Saitoh Y

更新日期：1984-02-01 00:00:00

abstract：:The use of extracorporeal membrane oxygenator instead of standard cardiopulmonary bypass during lung transplantation is debatable. Moreover, recently, the concept of prolonged postoperative extracorporeal membrane oxygenator (ECMO) support has been introduced in many transplant centers to prevent primary graft dysfunc...

journal_title：Artificial organs

authors： Dell'Amore A,Campisi A,Congiu S,Mazzarra S,Pastore S,Dolci G,Baiocchi M,Frascaroli G

更新日期：2020-06-01 00:00:00

abstract：:The rapid acceleration of technology development is outpacing our ability to assess it objectively and competently. Our challenge is to develop new assessment methods that take into account the fast moving nature of technology development while still protecting the patients' and the public interest. ...

journal_title：Artificial organs

authors： Abele JE

更新日期：1998-01-01 00:00:00

abstract：:Small blood vessels may play a more important role in artificial heart (AH) recipients than ever suspected before. Observations of elevated total peripheral resistance, low hematocrit, reduced oncotic pressure, high circulating blood volume, and arterial pulsations with nonpulsatile devices require consideration of pe...

journal_title：Artificial organs

authors： Lübbe AS

更新日期：1988-02-01 00:00:00

abstract：:Although it is now understood that trained skeletal muscle can generate enough steady-state power to provide significant circulatory support, there are currently no means by which to tap this endogenous energy source to aid the failing heart. To that end, an implantable muscle energy converter (MEC) has been construct...

journal_title：Artificial organs

authors： Trumble DR,Melvin DB,Byrne MT,Magovern JA

更新日期：2005-09-01 00:00:00

abstract：:Left ventricular assist devices (LVADs) are increasingly being used as life-saving therapy in patients with end-stage heart failure. The changes in spirometry following LVAD implantation and subsequent unloading of the left ventricle and pulmonary circulation are unknown. In this study, we explored long-term changes i...

journal_title：Artificial organs

authors： Mohamedali B,Bhat G,Yost G,Tatooles A

更新日期：2015-12-01 00:00:00

abstract：:This study probed the changes of keratocytes cultured under simulated microgravity. Keratocytes were isolated from rabbit corneas using collagenase digestion method. Cells were seeded in a 55-mL capacity high-aspect-ratio vessel (HARV) of rotary cell culture system (RCCS) at a density of 1 x 10(4) cells/mL. Dehydrated...

journal_title：Artificial organs

authors： Chen J,Chen R,Gao S

更新日期：2007-09-01 00:00:00

abstract：:Monoclonal antibodies for targeting cytotoxic conjugates to tumor cells are currently being evaluated together with extracorporeal affinity adsorption. The aim of the adsorption was to reduce undesired side effects in normal organs and to increase the tumor-to-normal tissue ratios. This technique is also applicable to...

journal_title：Artificial organs

authors： Mårtensson L,Nilsson R,Sjögren HO,Strand SE,Tennvall J

更新日期：2007-04-01 00:00:00

abstract：:Hemodialysis vascular access (VA) stenosis remains a frequent complication. However, early detection is challenging and costly. The aim of this in vitro study was to assess a new detection method based on pulse pressure analysis at the hemodialysis needle. A silicon model of a radiocephalic arteriovenous fistula was b...

journal_title：Artificial organs

authors： Van Canneyt K,Planken RN,Eloot S,Segers P,Verdonck P

更新日期：2010-02-01 00:00:00

abstract：:Implantable ventricular assist devices have proven efficacious as a bridge to transplantation and as a bridge to recovery. Although current indications for use of assist devices are somewhat limited, they are likely to expand in the upcoming years, including their use as destination therapy for end-stage heart failure...

journal_title：Artificial organs

authors： Hampton CR,Verrier ED

更新日期：2002-11-01 00:00:00

abstract：:Technological innovations in pediatric extracorporeal life support circuits can reduce system-related complications and may improve patients' outcome. The Deltastream DP3 (Medos Medizintechnik AG, Stolberg, Germany) is a novel rotational pump with a diagonally streamed impeller that can be used over a broad range of f...

journal_title：Artificial organs

authors： Stiller B,Houmes RJ,Rüffer A,Kumpf M,Müller A,Kipfmüller F,Köditz H,Herber Jonat S,Schmoor C,Benk C,Tibboel D,Fleck T

更新日期：2018-04-01 00:00:00

abstract：:Methods to predict and control cardiac output (CO) accurately in total artificial heart (TAH) recipients have varied significantly in the last few decades. Early models exhibited minimal control mechanisms and involved fixed pumping parameters. Elaborate electromechanical systems that have recently evolved require int...

journal_title：Artificial organs

authors： White RK,Olsen DB

更新日期：1991-10-01 00:00:00

abstract：:Loss of photoreceptor cells is one of the major causes of blindness. Several groups are exploring the functional replacement of photoreceptors by a retinal prosthesis. The goal of this study was to simulate the vision levels that recipients of retinal prostheses with 4 x 4, 6 x 10, and 16 x 16 electrode arrays may exp...

journal_title：Artificial organs

authors： Hayes JS,Yin VT,Piyathaisere D,Weiland JD,Humayun MS,Dagnelie G

更新日期：2003-11-01 00:00:00

abstract：:We developed a new left ventricular (LV) assist catheter (transaortic valve from LV to femoral artery) that is implemented percutaneously and exerted as a synchronous pulsatile partial LV flow support with conventional intraaortic balloon pump (IABP) driving system and centrifugal pump system. We investigated whether ...

journal_title：Artificial organs

authors： Ide H,Yamaguchi A,Ino T,Matsumoto H,Fujimasa I

更新日期：1992-06-01 00:00:00

abstract：:Cardiac surgery with cardiopulmonary bypass is associated with a systemic inflammatory response syndrome. The major clinical features of this include a reduction of pulmonary compliance and increased extracellular fluids, with increased pulmonary shunt fraction similar to acute respiratory distress syndrome, thus resu...

journal_title：Artificial organs

authors： Luciani R,Goracci M,Simon C,Principe F,Fazzari L,Punzo G,Menè P

更新日期：2009-08-01 00:00:00