Systemic consequences of ventricular assist devices: alterations of coagulation, immune function, inflammation, and the neuroendocrine system.

abstract：:Biofilms are communities of bacteria that can cause infections which are resistant to the immune system and antimicrobial treatments, posing a significant threat for patients with implantable and indwelling medical devices. The purpose of our research was to determine if utilizing specific parameters for electric curr...

journal_title：Artificial organs

authors： Haddad PA,Mah TF,Mussivand T

更新日期：2016-08-01 00:00:00

abstract：:This work describes the preparation and characterization of anionic collagen composites with rhamsan and vinylidene fluoride-trifluorethylene with improved rheological and dielectric properties without loss of collagen secondary structure with an interaction occurring between both macromolecules of the composites. On ...

journal_title：Artificial organs

authors： Goissis G,Piccirili L,Goes JC,de Guzzi Plepis AM,Das-Gupta DK

更新日期：1998-03-01 00:00:00

abstract：:Our study investigated the reliability of appearance of rapid atrial swirl flow (RASF) by ultrasonography (US) in the right atrium (RA), which occurred as a result of rapid isotonic saline infusion (RISI) into the central venous catheter (CVC), in predicting catheter tip position. This prospective observational study ...

journal_title：Artificial organs

authors： Yesilbas O,Sevketoglu E,Kihtir HS,Talip Petmezci M,Akcay N,Kocoglu Barlas U,Palabiyik F

更新日期：2018-12-01 00:00:00

abstract：:The aim of this work is to construct a computational fluid dynamics model capable of simulating the transient non-Newtonian process of apheresis. A Lagrangian-Eulerian model has been developed which tracks the blood particles within a two-dimensional flow configuration. Within the Eulerian method, the fluid mass and m...

journal_title：Artificial organs

authors： De Gruttola S,Boomsma K,Poulikakos D

更新日期：2005-12-01 00:00:00

abstract：:The purpose of this study was the investigation of the usability and ergonomics of ventricular assist devices (VADs) in everyday usage. Patients with four different VAD types were observed. After implantation, instruction, and discharge from the hospital, the patients returned on a regular basis to the outpatient clin...

journal_title：Artificial organs

authors： Geidl L,Zrunek P,Deckert Z,Zimpfer D,Sandner S,Wieselthaler G,Schima H

更新日期：2009-09-01 00:00:00

abstract：:Secondary flow in the centrifugal blood pump helps to enhance the washout effect and to minimize thrombus formation. On the other hand, it has an adverse effect on pump efficiency. Excessive secondary flow may induce hemolytic effects. Understanding the secondary flow is thus important to the design of a compact, effi...

journal_title：Artificial organs

authors： Watanabe N,Masuda T,Iida T,Kataoka H,Fujimoto T,Takatani S

更新日期：2005-01-01 00:00:00

abstract：:A woven fabric graft made of ultrafine polyester fibers (UFPF) (Toray Graft, water porosity: 100 ml/min/cm2:120 mm Hg H2O) was clinically applied in 81 cases (28 thoracic aortic aneurysms, 6 thoracoabdominal aortic aneurysms, 42 abdominal aortic aneurysms, and 5 atherosclerotic obstructions of the peripheral arteries)...

journal_title：Artificial organs

authors： Satoh S,Niu S,Kanda K,Hirai J,Nakazima S,Wada Y,Oka T,Noishiki Y

更新日期：1995-01-01 00:00:00

abstract：:Artificial cells are prepared in the laboratory for medical and biotechnological applications. Encapsulated cells are being studied for the treatment of diabetes, liver failure, and other conditions. More recently, there have been extensive studies into the use of encapsulated genetically engineered cells for gene the...

journal_title：Artificial organs

authors： Chang TM

更新日期：1998-11-01 00:00:00

abstract：:Stents are small, usually metallic tubes that are intended to prop open arteries blocked with atherosclerotic plaques. While stents have been used successfully in recent years, they still suffer from failure due to development of new tissue in stented segment (restenosis). Variations in the failure rates associated wi...

journal_title：Artificial organs

authors： Frank AO,Walsh PW,Moore JE Jr

更新日期：2002-07-01 00:00:00

abstract：:The purpose of this study was to characterize changes in hepatic venous pressures in patients with chronic hepatitis C. The histology and laboratory data from patients with chronic hepatitis C who underwent a transjugular liver biopsy (TJLB) and hepatic venous pressure gradient measurement were analyzed. Portal hypert...

journal_title：Artificial organs

authors： Khurana S,Simcox T,Twaddell W,Drachenberg C,Flasar M

更新日期：2010-07-01 00:00:00

abstract：:Hemodynamic control of left ventricular assist devices (LVADs) is generally a complicated problem due to diverse operating environments and the variability of the patients: both the changes in the circulatory and metabolic parameters as well as disturbances that require adjustment to the operating point. This challeng...

journal_title：Artificial organs

authors： Choi S,Boston JR,Antaki JF

更新日期：2007-02-01 00:00:00

abstract：:A pneumatically driven artificial heart with a tubular silicone rubber membrane and disc valves was used for functional heart replacement in the paracorporeal mode. A fluidic drive system allows adjustment of the heart rate, positive and negative pressures and systole/diastole ratio. Since August, 1977, the artificial...

journal_title：Artificial organs

authors： Turina MT,Bosio R,Senning A

更新日期：1978-08-01 00:00:00

abstract：:Although it is now understood that trained skeletal muscle can generate enough steady-state power to provide significant circulatory support, there are currently no means by which to tap this endogenous energy source to aid the failing heart. To that end, an implantable muscle energy converter (MEC) has been construct...

journal_title：Artificial organs

authors： Trumble DR,Melvin DB,Byrne MT,Magovern JA

更新日期：2005-09-01 00:00:00

abstract：:The growing practice of dialyzer reuse in recent years is mainly based on medical and economic considerations. However, adverse reactions such as immunohemolytic anemia due to anti-Nform antibody associated with dialyzer reuse have been reported. In this study, scanning electron microscopy and cytologic staining were ...

journal_title：Artificial organs

authors： Ng YY,Yang AH,Wong KC,Lan HY,Hung TL,Kerr PG,Huang TP

更新日期：1996-01-01 00:00:00

abstract：:Infusion into rats of the polycation hexadimethrine (HDM) leads to onset of massive proteinuria, which recovers when the infusion is stopped. Several lines of evidence indicate that the proteinuria results from binding of HDM to polyanions of the glomerular filter, with neutralization of shielding of their charges. To...

journal_title：Artificial organs

authors： Hunsicker LG,Bertolatus JA

更新日期：1987-12-01 00:00:00

abstract：:Atherosclerosis is accelerated in dialysis patients, but less is known about asymptomatic atherosclerosis and major risk factors in patients with different stages of chronic kidney disease (CKD). We compared intima media thickness (IMT) and plaque occurrence in the carotid arteries in 104 nondiabetic patients (stages ...

journal_title：Artificial organs

authors： Ekart R,Hojs R,Bevc S,Balon BP

更新日期：2008-03-01 00:00:00

abstract：:A pseudo-one compartment model has been proposed to describe phosphorus kinetics during hemodialysis and the immediate post-dialysis period. This model assumes that phosphorus mobilization from tissues is proportional to the difference between the pre-dialysis serum concentration (a constant) and the instantaneous ser...

journal_title：Artificial organs

authors： Leypoldt JK,Agar BU,Cheung AK,Bernardo AA

更新日期：2017-11-01 00:00:00

abstract：:Continuous and intermittent high shear were loaded to red blood cells in a cone and a plate rheoscope. The mechanical damage to red cells was compared for continuous and intermittent shear. The intermittent shear was achieved by alternately starting and stopping shear repeatedly. In the case of intermittent shear load...

journal_title：Artificial organs

authors： Mizunuma H,Sakai S

更新日期：2007-06-01 00:00:00

abstract：:Cardiopulmonary bypass (CPB) has a risk of cerebral injury, with an important role of gaseous micro-emboli (GME) coming from the CPB circuit. Pulsatile perfusion is supposed to perform specific conditions for supplementary GME activity. We aimed to determine whether pulsatile CPB augments production and delivery of GM...

journal_title：Artificial organs

authors： Dodonov M,Milano A,Onorati F,Dal Corso B,Menon T,Ferrarini D,Tessari M,Faggian G,Mazzucco A

更新日期：2013-04-01 00:00:00

abstract：:As known from patients with pulsatile ventricular assist devices (VADs), early mobilization, physical exercise, and return to normal life are essential for optimal recovery. Recently, implantable rotary pumps became available for extended left ventricular support as bridges to transplantation. Modified procedures are ...

journal_title：Artificial organs

authors： Wieselthaler GM,Schima H,Dworschak M,Quittan M,Nuhr M,Czerny M,Seebacher G,Huber L,Grimm M,Wolner E

更新日期：2001-05-01 00:00:00

abstract：:The neutralization of bacterial endotoxins (ET) is still an unsolved problem in therapeutic medicine. The efficacy of anti-endotoxin antibodies or receptor antagonists and other substances interfering with the endotoxin-induced pathomechanisms is dependent on an intact cellular degradation system of the host. However,...

journal_title：Artificial organs

authors： Mitzner S,Schneidewind J,Falkenhagen D,Loth F,Klinkmann H

更新日期：1993-09-01 00:00:00

abstract：:The on-line measurement during hemodialysis of ionic dialysance provides an estimation of urea clearance with a good and already proven correlation. Some discrepancies remain controversial, and the influence of the dialyzer membrane is still being debated. Eighty-eight measurements of ionic dialysance (ID) were perfor...

journal_title：Artificial organs

authors： Mercadal L,Petitclerc T,Jaudon MC,Béné B,Goux N,Jacobs C

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Ventricular assist devices are gaining ground in the therapeutic treatment of chronic heart failure. These devices are sometimes used as a bridge to recovery by unloading the left ventricle (LV) and restoring its function. It is therefore important to preserve the heart muscle and apply less invasive implant...

journal_title：Artificial organs

authors： Vandenberghe S,Nishida T,Segers P,Meyns B,Verdonck P

更新日期：2004-07-01 00:00:00

abstract：:We report on the most recent data confirming the angiographic and pathological efficacy of LDL-apheresis for coronary atherosclerosis of a familial hypercholesterolemia (FH) patient using collected data of a large number of cases and especially of one autopsy case. Changes in coronary artery stenosis have been assesse...

journal_title：Artificial organs

authors： Koga N,Iwata Y,Yamamoto A

更新日期：1992-04-01 00:00:00

abstract：:Platelet-rich plasma (PRP) contains many growth factors that are involved in tissue regeneration processes. For successful tissue regeneration, protein growth factors require a delivery vehicle for long-term and sustained release to a defect site in order to maintain their bioactivity. Previously, we showed that hepar...

journal_title：Artificial organs

authors： La WG,Yang HS

更新日期：2015-04-01 00:00:00

abstract：:In this study, a detection algorithm for suction and regurgitation of the centrifugal pump during left heart bypass without relying on external flow or pressure sensors was developed and evaluated in acute studies using adult goats. The detection scheme relies on power spectral density (PSD) analysis of the motor curr...

journal_title：Artificial organs

authors： Yuhki A,Hatoh E,Nogawa M,Miura M,Shimazaki Y,Takatani S

更新日期：1999-06-01 00:00:00

abstract：:Current hemodialysis treatment is insufficient because of intermittent treatment and loss of tubular function. In order to overcome the loss of tubular function, a bioartificial kidney has been developed consisting of continuous hemofiltration (CHF) with 10 L/day of filtrate and a bioartificial tubule device using pro...

journal_title：Artificial organs

authors： Saito A

更新日期：2004-01-01 00:00:00

abstract：:A comparative study of the thrombogenicity of several microporous membranes was performed using an ex vivo system simulating the conditions in an artificial lung. A study of platelet adhesion and adsorbed protein layer indicated that the membranes separated into three groups. Copolyurethane membranes adsorbed very few...

journal_title：Artificial organs

authors： Knight PM,Lyman DJ

更新日期：1985-02-01 00:00:00

abstract：:Molecular biology has been moving swiftly toward clarifying the entire genome of organisms, including human. The human genome efforts that promote this transaction are characterized by the large-scale, high throughput production of data about the structure of the genome of the molecular level and its computer-assisted...

journal_title：Artificial organs

authors： Matsubara K

更新日期：1996-08-01 00:00:00

abstract：:The combination of plasma exchange and continuous hemofiltration was applied to patients with acute liver failure, and its clinically advantageous effects were evaluated. This procedure was found to be a powerful approach in decreasing patient morbidity; however, the effect was temporary and the patients finally died....

journal_title：Artificial organs

authors： Matsubara S

更新日期：1994-05-01 00:00:00