Modeling of a rotary blood pump.

abstract：:We have been developing some types of microcapsule suspensions with polyurethane membranes to evaluate the absolute hemolytic characteristics of the centrifugal blood pumps used in circulatory support devices such as artificial hearts. In order to facilitate/realize hemolysis testing on centrifugal blood pumps that ha...

journal_title：Artificial organs

authors： Maruyama O,Yamaguchi K,Nishida M,Onoguchi T,Tsutsui T,Jikuya T,Yamane T

更新日期：2008-02-01 00:00:00

abstract：:The most common method of controlling acidemia during lung-protective ventilation is CO₂ removal with an extracorporeal lung assist (ECLA) system. Another possibility to prevent acidemia is based on intravenous (i.v.) application of tris-hydroxymethyl-aminomethane (3 mol/L, THAM) buffer, which can bind hydrogen proton...

journal_title：Artificial organs

authors： Russ M,Deja M,Ott S,Bedarf J,Keckel T,Hiebl B,Wagner JJ,Unger JK

更新日期：2011-06-01 00:00:00

abstract：:Bubble blood oxygenators equipped with baffles of various types in the oxygenating column were studied. The rate of hemolysis, the volumetric coefficient for oxygen absorption into blood, and the fractional gas holdup were found to be affected mainly by the superficial gas velocity. When compared with the conventional...

journal_title：Artificial organs

authors： Ohshima N,Yoshido F

更新日期：1979-05-01 00:00:00

abstract：:Two series of experiments were conducted to assess the potential of artificial ventricular bypass in restoring cardiac activity. One series evaluated use of a paracorporeal left ventricle in 17 calves; the other evaluated biventricular bypass in 11 calves. Module pumps with a seamless blood chamber of polyurethane wer...

journal_title：Artificial organs

authors： Tolpekin VE,Koblov LF,Kuvaev AE,Gasanov EK

更新日期：1987-02-01 00:00:00

abstract：:For introduction of a left atrial (LA) cannula by the transseptal puncture technique, we examined the feasibility of using biplane transesophageal echocardiography (B-TEE). A transseptal puncture was performed on 15 patients (3 male; 12 female; mean age, 48.9 +/- 11.2 years) by B-TEE guide during percutaneous transven...

journal_title：Artificial organs

authors： Kyo S,Motoyama T,Miyamoto N,Noda H,Dohi Y,Omoto R

更新日期：1992-08-01 00:00:00

abstract：:Porous polyurethane (nonwoven) was used for the development of tracheal prosthesis, which--in a special testing design--was adapted to shape and biomechanic properties of the natural organ. This prosthesis was implanted into 19 beagle dogs using inverted, everted, and end-to-end anastomosis. Insufficiency of the anast...

journal_title：Artificial organs

authors： Schauwecker HH,Gerlach J,Planck H,Bücherl ES

更新日期：1989-06-01 00:00:00

abstract：:Ligament reconstruction using a tissue-engineered artificial ligament (TEAL) requires regeneration of the ligament-bone junction such that fixation devices such as screws and end buttons do not have to be used. The objective of this study was to develop a TEAL consisting of elastin-coated polydioxanone (PDS) sutures c...

journal_title：Artificial organs

authors： Hirukawa M,Katayama S,Sato T,Inoue K,Niwa K,Ito N,Hattori T,Hosoi T,Unno H,Suzuki Y,Hasegawa M,Miyamoto K,Horiuchi T

更新日期：2018-07-01 00:00:00

abstract：:The rapid acceleration of technology development is outpacing our ability to assess it objectively and competently. Our challenge is to develop new assessment methods that take into account the fast moving nature of technology development while still protecting the patients' and the public interest. ...

journal_title：Artificial organs

authors： Abele JE

更新日期：1998-01-01 00:00:00

abstract：:Extracorporeal life support (ECLS) has been increasingly utilized to manage cardiac and pulmonary dysfunction. The impact of obesity on outcomes of ECLS is poorly defined. The purpose of the study was to compare in-hospital mortality, resource use, complications, and readmissions in obese versus non-obese patients rec...

journal_title：Artificial organs

authors： Christian-Miller N,Hadaya J,Nakhla M,Sanaiha Y,Madrigal J,Emami S,Cale M,Sareh S,Benharash P

更新日期：2020-11-01 00:00:00

abstract：:Recent progress in the development of implantable rotary blood pumps realized long-term mechanical circulatory support (MCS) for bridge to transplant, bridge to recovery, or a destination therapy. Meanwhile, a short-term MCS system is becoming necessary for bridge to decision. We developed a novel inflow cannula for t...

journal_title：Artificial organs

authors： Sumikura H,Toda K,Takewa Y,Tsukiya T,Ohnuma K,Sasagawa M,Watanabe F,Ugawa J,Taenaka Y,Tatsumi E

更新日期：2011-08-01 00:00:00

abstract：:The present study aimed to determine the feasibility of constructing a reinforced autologous vascular graft by combining the advantages of fibrin gel as an autologous cell carrier material with the inherent mechanical strength of an integrated mesh structure. It was hypothesized that the mesh and dynamic culture condi...

journal_title：Artificial organs

authors： Tschoeke B,Flanagan TC,Cornelissen A,Koch S,Roehl A,Sriharwoko M,Sachweh JS,Gries T,Schmitz-Rode T,Jockenhoevel S

更新日期：2008-10-01 00:00:00

abstract：:Cybernetics-based concepts can allow for complete independence for paralyzed individuals, including sensory motor recovery. Spinal cord injuries are responsible for a huge stress on health and a financial burden to society. This article focuses on novel procedures such as functional diagnosis for paraplegics and tetra...

journal_title：Artificial organs

authors： Varoto R,Cliquet A Jr

更新日期：2015-10-01 00:00:00

abstract：:In a controlled European multicenter study, clinical tolerance of subcutaneously administered recombinant human erythropoietin (rh-EPO) therapy and its influence on the course of illness in 362 hemodialyzed patients (162 males, 200 females) from 16 European dialysis centers was studied. Of these, 181 patients served a...

journal_title：Artificial organs

authors： Klinkmann H,Wieczorek L,Scigalla P

更新日期：1993-04-01 00:00:00

abstract：:Bone marrow mesenchymal stem cells (MSCs) have demonstrated their pluripotency to differentiate into different cell lineages and may be an alternative cell source for vascular tissue engineering. The objective of this study is to create small diameter vessels by seeding and culture of genetically modified MSCs onto a ...

journal_title：Artificial organs

authors： Zhang J,Qi H,Wang H,Hu P,Ou L,Guo S,Li J,Che Y,Yu Y,Kong D

更新日期：2006-12-01 00:00:00

abstract：:Mechanical circulatory support (MCS) devices for pediatric patients continue to lag in development behind those for adults. There is no heart pump with the design innovation to support dysfunctional states of heart failure and the anatomic heterogeneity of cardiac defects in pediatric patients. To address this unmet n...

journal_title：Artificial organs

authors： Fox C,Sarkisyan H,Stevens R,Arabia F,Fischer W,Rossano J,Throckmorton A

更新日期：2019-11-01 00:00:00

abstract：:Nonpulsatile blood pumps are mainly used in extracorporeal life support systems. Although pulsating blood flow is known to be physiological, a pulsatile pump is not commonly applied in a circuit with a membrane oxygenator because of damage to the blood cells. The hypothesis that the placement of a pressure-relieving c...

journal_title：Artificial organs

authors： Kim TS,Sun K,Lee KB,Lee HW,Baek KJ,Park SY,Son HS,Kim KT,Kim HM

更新日期：2004-12-01 00:00:00

abstract：:In this study a highly biocompatible polymer membrane was prepared by surface modification. An artificial cornea was also developed for clinical applications. Silicone rubber (SR) membrane was grafted with hydrophilic monomers such as 2-hydroxyethyl methacrylate (HEMA) and acrylic acid by plasma induced grafted polyme...

journal_title：Artificial organs

authors： Hsiue GH,Lee SD,Chang PC

更新日期：1996-11-01 00:00:00

abstract：:Upon introducing off-pump coronary artery bypass grafting (CABG), the indications for CABG were expanded to include patients who previously had no operative indications. For accurate anastomosis, various devices and methods have been developed. Bradycardia is easily induced by drug administration. However, this method...

journal_title：Artificial organs

authors： Kuniyoshi Y,Koja K,Miyagi K,Shimoji M,Uezu T,Arakaki K,Yamashiro S,Mabuni K,Senaha S

更新日期：2002-10-01 00:00:00

abstract：:Progress in the techniques for surgical implantation of the artificial heart has progressed in parallel with the technology and design of the prosthesis. In the author's first experience with total artificial heart (TAH) implantation (1968) a trans-sternal split was used opening the sixth intercostal space on the righ...

journal_title：Artificial organs

authors： Olsen DB,Fukumasu H,Kolff J,Nakagaki M,Finch LR,Kolff WJ

更新日期：1977-11-01 00:00:00

abstract：:A multi-compartment capillary membrane culture model with independently perfused three-dimensionally woven capillaries was developed for immobilization of hepatocytes in bioreactors. This enables spatial restructuring of cells and enhanced mass transfer performance with more efficient oxygenation and metabolite exchan...

journal_title：Artificial organs

authors： Gerlach J,Schnoy N,Smith MD,Neuhaus P

更新日期：1994-03-01 00:00:00

abstract：:A computational fluid dynamic model to assess the impact of flow-diverter device on intra-aneurysmal flow in complex aortic aneurysm from the viewpoint of hemodynamics is presented. The aim of this study is to investigate the hemodynamic effects of an endovascular flow-diverter technique using multiple overlapping unc...

journal_title：Artificial organs

authors： Yeow SL,Leo HL

更新日期：2018-02-01 00:00:00

abstract：:With the incidence of end-stage heart failure steadily increasing, the need for a practical total artificial heart (TAH) has never been greater. Continuous flow TAHs (CFTAH) are being developed using rotary blood pumps (RBPs), leveraging their small size, mechanical simplicity, and excellent durability. To completely ...

journal_title：Artificial organs

authors： Nestler F,Timms DL,Stevens M,Bradley AP,Wilson SJ,Kleinheyer M,Lovell N,Frazier OH,Cohn WE

更新日期：2020-06-01 00:00:00

abstract：:The aim of this work is the evaluation of four different heat exchangers used for myocardium during cardioplegic system in cardiac surgeries. Four types of shell and tube heat exchangers made of different exchange elements were constructed, as follows: stainless steel tubes, aluminium tubes, polypropylene hollow fiber...

journal_title：Artificial organs

authors： Drummond M,Novello WP,de Arruda AC,Braile DM

更新日期：2003-05-01 00:00:00

abstract：:Artificial oxygen (O2 ) carriers were reported to be protective in ischemia/reperfusion (I/R) in various organs including the heart. In the current study, 20 rats underwent ligation (MI) of the left anterior descending artery, were treated with 10 mL/kg of PEGylated carboxyhemoglobin bovine (SANGUINATE, S+, n = 10) or...

journal_title：Artificial organs

authors： Kawaguchi AT,Salybekov AA,Yamano M,Kitagishi H,Sekine K,Tamaki T

更新日期：2018-12-01 00:00:00

abstract：:Electrolyzed water accelerated the healing of full-thickness cutaneous wounds in rats, but only anode chamber water (acid pH or neutralized) was effective. Hypochlorous acid (HOCl), also produced by electrolysis, was ineffective, suggesting that these types of electrolyzed water enhance wound healing by a mechanism un...

journal_title：Artificial organs

authors： Yahagi N,Kono M,Kitahara M,Ohmura A,Sumita O,Hashimoto T,Hori K,Ning-Juan C,Woodson P,Kubota S,Murakami A,Takamoto S

更新日期：2000-12-01 00:00:00

abstract：:Widespread use of heart transplantation is limited by the scarcity of donor organs. Total artificial heart (TAH) development has been pursued to address this shortage, especially to treat patients who require biventricular support. We have developed a novel TAH that utilizes a continuously spinning rotor that shuttles...

journal_title：Artificial organs

authors： Glynn J,Song H,Hull B,Withers S,Gelow J,Mudd J,Starr A,Wampler R

更新日期：2017-10-01 00:00:00

abstract：:The aim of the present study was to compare the effects of ProTaper Gold, WaveOne Gold, ProTaper Universal, and WaveOne instruments on the amount of apically extruded debris. Eighty mandibular premolar teeth with straight root canals were selected and assigned to four groups (n = 20). The root canals were instrumented...

journal_title：Artificial organs

authors： Karataş E,Ersoy İ,Gündüz HA,Uygun AD,Kol E,Çakıcı F

更新日期：2016-08-01 00:00:00

abstract：:To remove anti-DNA antibodies from a patient's plasma with systemic lupus erythematosus (SLE), a DNA immunoadsorbent was developed by covalently coupling calf thymus DNA on activated Sepharose 4FF. Sepharose 4FF was activated with 5-norbornene-2,3-dicarboximido carbonochloridate (Cl-CO-ONB), which was proven to be a v...

journal_title：Artificial organs

authors： Kong DL,Schuett W,Boeden HF,Kunkel S,Holtz M,Matic G,Yamada R,Yu YT,Klinkmann H

更新日期：2000-11-01 00:00:00

abstract：:Growth factors and morphogens secreted by bone marrow mesenchymal stem cells (BMSCs) of bone marrow fluid may promote tooth regeneration. Accordingly, a tissue engineering approach was utilized to develop an economical strategy for obtaining the growth factors and morphogens from BMSCs. Unerupted second molar tooth bu...

journal_title：Artificial organs

authors： Kuo TF,Lin HC,Yang KC,Lin FH,Chen MH,Wu CC,Chang HH

更新日期：2011-02-01 00:00:00

abstract：:The objective of our study was to investigate chondrogenesis potential of human adipose-derived mesenchymal stromal cells (MSCs), using as a positive control a human source of cartilage-derived progenitor cells (PCs). This source of PCs was recently described by our group and dwells on the surface of nasoseptal cartil...

journal_title：Artificial organs

authors： Baptista LS,Silva KR,Pedrosa CS,Amaral RJ,Belizário JV,Borojevic R,Granjeiro JM

更新日期：2013-12-01 00:00:00