Miniaturized centrifugal ventricular assist device for bridge to decision: Preclinical chronic study in a bovine model.

abstract：:Growth factors and morphogens secreted by bone marrow mesenchymal stem cells (BMSCs) of bone marrow fluid may promote tooth regeneration. Accordingly, a tissue engineering approach was utilized to develop an economical strategy for obtaining the growth factors and morphogens from BMSCs. Unerupted second molar tooth bu...

journal_title：Artificial organs

authors： Kuo TF,Lin HC,Yang KC,Lin FH,Chen MH,Wu CC,Chang HH

更新日期：2011-02-01 00:00:00

abstract：:The coronary arteries of the goat heart were studied using angiographic techniques and molds of the coronary vessel trees. Blood supplies to the left and right ventricles, interventricular septum, atrioventricular node, and apex of the caprine heart were studied. The goat possesses a left dominant pattern of coronary ...

journal_title：Artificial organs

authors： Lipovetsky G,Fenoglio JJ,Gieger M,Srinivasan MR,Dobelle WH

更新日期：1983-05-01 00:00:00

abstract：:Artificial cells are prepared in the laboratory for medical and biotechnological applications. Encapsulated cells are being studied for the treatment of diabetes, liver failure, and other conditions. More recently, there have been extensive studies into the use of encapsulated genetically engineered cells for gene the...

journal_title：Artificial organs

authors： Chang TM

更新日期：1998-11-01 00:00:00

abstract：:In vitro tests have shown that electric currents may lead either to relaxation or contraction of the bowel wall. Because voluntary changes of the intestinal motility could be useful in the treatment of intestinal disorders, we investigated the reactions elicited by electrostimulation of the small intestine in the inta...

journal_title：Artificial organs

authors： Moritz A,Grundfest-Broniatowski S,Ilyes L,Kasick J,Jacobs G,Olsen E,Nosé Y

更新日期：1989-04-01 00:00:00

abstract：:The aim of this study was to characterize and compare human great saphenous veins (HGSVs), HGSV cryoallografts, expanded polytetrafluoroethylene (ePTFE) segments, and elastic and muscular arteries' biomechanics, so as to identify if the biomechanical coupling and the HGSV advantages with respect to ePTFE depend on the...

journal_title：Artificial organs

authors： Bia D,Zócalo Y,Pessana F,Armentano R,Pérez H,Saldías M,Alvarez I

更新日期：2007-11-01 00:00:00

abstract：:Following implantation of a left ventricular assist device (LVAD), acceptable functional performance is now being achieved; however, peak VO2 and peak work load (watts) remain considerably limited. Maximum physical capacity is essentially dependent on generated cardiac output (CO) and arteriovenous oxygen difference (...

journal_title：Artificial organs

authors： Schmidt T,Bjarnason-Wehrens B,Mommertz S,Hannig M,Schulte-Eistrup S,Willemsen D,Reiss N

更新日期：2018-07-01 00:00:00

abstract：:The objective of this study was to evaluate the hemodynamic performance and gaseous microemboli (GME) handling ability of a simulated neonatal extracorporeal life support (ECLS) circuit with an in-line continuous renal replacement therapy (CRRT) device. The circuit consisted of a Maquet RotaFlow centrifugal pump or HL...

journal_title：Artificial organs

authors： Shank KR,Profeta E,Wang S,O'Connor C,Kunselman AR,Woitas K,Myers JL,Ündar A

更新日期：2018-04-01 00:00:00

abstract：:Rotary ventricular assist devices (VADs) are primarily used during surgery and short-term postoperative assistance. There are issues involving the use of rotary VADs including the behavior of flow emanating from the assist device which might induce flow irregularities that could potentially lead to stroke or cerebrova...

journal_title：Artificial organs

authors： Manning KB,Miller GE

更新日期：2002-08-01 00:00:00

abstract：:In clinical application of rotary blood pumps, flow obstruction as a result of suction of the inflow cannula, kinking of tubing, or thrombus formation occurs quite frequently. Early detection of such problems is essential to avoid hemolysis, tissue degradation, or release of thrombi to the patient. A program was devel...

journal_title：Artificial organs

authors： Holzer S,Scherer R,Schmidt C,Schwendenwein I,Wieselthaler G,Noisser R,Schima H

更新日期：1995-07-01 00:00:00

abstract：:Patients with kidney failure can only survive with some form of kidney replacement (transplant or dialysis). Unfortunately, innovations in kidney replacement therapy lag behind many other medical fields. This study compiles expert opinions on candidate technologies for future kidney replacement therapies. A worldwide ...

journal_title：Artificial organs

authors： Pereira Cabral B,Bonventre JV,Wieringa F,Mota FB

更新日期：2020-07-22 00:00:00

abstract：:Turbulent blood flow in medical devices contributes to blood trauma, yet the exact mechanism(s) have not been fully elucidated. Local turbulent stresses, viscous stresses, and the rate of dissipation of the turbulent kinetic energy have been proffered as hypotheses to describe and predict blood damage. In this work, s...

journal_title：Artificial organs

authors： Ozturk M,O'Rear EA,Papavassiliou DV

更新日期：2015-12-01 00:00:00

abstract：:Chronic kidney disease is increasing in both developed and emerging countries with progressive encroachment on health services budgets. In spite of the lack of accurate registries, we tried to focus on the magnitude of the problem on different continents. Prevention of progression has been a remote but reachable goal....

journal_title：Artificial organs

authors： Hafez MH,Abdellatif DA,Elkhatib MM

更新日期：2006-07-01 00:00:00

abstract：:The presence in rat serum of three novel immunosuppressive proteins is associated with induction of tolerance after liver grafting. One of these, KX-5 (40 kilodalton molecular weight) is present 40-100 days after grafting of DA liver into PVG, a combination in which liver grafts are not rejected; two others, KX-2 (87 ...

journal_title：Artificial organs

authors： Kamada N

更新日期：1996-10-01 00:00:00

abstract：:In vitro cardiovascular device performance evaluation in a mock circulation loop (MCL) is a necessary step prior to in vivo testing. A MCL that accurately represents the physiology of the cardiovascular system accelerates the assessment of the device's ability to treat pathological conditions. To serve this purpose, a...

journal_title：Artificial organs

authors： Timms DL,Gregory SD,Greatrex NA,Pearcy MJ,Fraser JF,Steinseifer U

更新日期：2011-04-01 00:00:00

abstract：:Characteristics of morphology, cardiac function, and cardiac reserve at late state were evaluated at rest, by changing the pacing rates, and after exercise in patients with ventricular pacemakers for isolated congenital complete atrioventricular block. Heart size was reduced statistically after pacemaker implantation,...

journal_title：Artificial organs

authors： Nawa S,Kioka Y,Shimizu A,Tsuji H,Miyachi Y,Ebara K,Kino K,Shigenobu M,Murakami T,Senoo Y

更新日期：1987-06-01 00:00:00

abstract：:Tissue engineering can improve the former limitations of artificial organs. This article reports the long-term clinical results of grafts constructed with fragmented autologous adipose tissue. We did a retrospective analysis of a series of 53 patients with lower leg ischemia that received 69 fragmented adipose tissue ...

journal_title：Artificial organs

authors： Karube N,Soma T,Noishiki Y,Yamazaki I,Kosuge T,Ichikawa Y,Takanashi Y

更新日期：2001-03-01 00:00:00

abstract：:In this pilot study, we assessed the feasibility of using positron emission tomography (PET) imaging for in vivo measurement of skeletal muscle ventricle (SMV) tissue blood flow. In 4 dogs, with SMVs prepared from their latissimus dorsi muscle, we quantified SMV tissue blood flow by PET and related it to the tissue fl...

journal_title：Artificial organs

authors： Singh TP,Greer K,Muzik O,Hammond RL,Stephenson LW,Di Carli MF

更新日期：2001-04-01 00:00:00

abstract：:Extracorporeal human lymphatic organs are expected to be excellent tools in the study of human molecular and cellular bases of the immunologic balance and tissue harmony. A rational approach and process to design a device and a procedure to recreate the human lymph node environment in vitro is described with emphasis ...

journal_title：Artificial organs

authors： Giese C,Demmler CD,Ammer R,Hartmann S,Lubitz A,Miller L,Müller R,Marx U

更新日期：2006-10-01 00:00:00

abstract：:The weight gain of IVOX devices removed from the first 49 human clinical trials patients after from 1 to 29 days of implantation into the venae caval blood stream has been assessed. Each patient had received sufficient systemic heparin to maintain activated clotting times between 150 and 200 s while the IVOX device wa...

journal_title：Artificial organs

authors： Imai H,Schaap RN,Mortensen JD

更新日期：1994-11-01 00:00:00

abstract：:In patients undergoing exchange-transfusion with hemoglobin (Hb)-based oxygen (O₂) carriers (HBOC), native Hb coexists with newly transfused Hb. The two Hb types share the same arterial and venous PO₂, but their affinities for O₂ vary. A simple spreadsheet model is described aiming at evaluating the contribution of ea...

journal_title：Artificial organs

authors： Samaja M,Terraneo L

更新日期：2012-02-01 00:00:00

abstract：:To assess the influence of hydration state on plasma volume (PV) changes during ultrafiltration, 11 clinically normhydrated patients on maintenance hemodialysis were studied intraindividually during 2 hydration states differing by 2-15% of lean body mass (LBM). Plasma volume was measured continually during a 15-min ul...

journal_title：Artificial organs

authors： Wizemann V,Leibinger A,Mueller K,Nilson A

更新日期：1995-05-01 00:00:00

abstract：:Implantable ventricular assist devices have proven efficacious as a bridge to transplantation and as a bridge to recovery. Although current indications for use of assist devices are somewhat limited, they are likely to expand in the upcoming years, including their use as destination therapy for end-stage heart failure...

journal_title：Artificial organs

authors： Hampton CR,Verrier ED

更新日期：2002-11-01 00:00:00

abstract：:The effects of pyridoxalated hemoglobin polyoxyethylene conjugate (PHP) and other hemoglobin-related substances on arterial blood pressure (ABP) and heart rate (HR) were examined. Infusion of PHP and other hemoglobin-related substances elevated ABP and increased HR. The degree of the increase in ABP and HR did not dif...

journal_title：Artificial organs

authors： Kida Y,Maeda M,Iwata S,Iwashita Y,Goto K,Nishi K

更新日期：1995-02-01 00:00:00

abstract：:There is increasing evidence showing that adult stem cells are useful for tissue regeneration. Bone marrow mesenchymal stem cells (MSCs) are self-renewing and are potent in differentiating into multiple cells and tissues. To investigate the practicability of repairing burn wounds with tissue-engineered (TE) skin combi...

journal_title：Artificial organs

authors： Liu P,Deng Z,Han S,Liu T,Wen N,Lu W,Geng X,Huang S,Jin Y

更新日期：2008-12-01 00:00:00

abstract：:The characteristic depressed hemodynamic state and gradually declining circulatory function in Fontan patients necessitates alternative postoperative management strategies incorporating a system level approach. In this study, the single-ventricle Fontan circulation is modeled by constructing a practical in vitro bench...

journal_title：Artificial organs

authors： Dur O,Lara M,Arnold D,Vandenberghe S,Keller BB,DeGroff C,Pekkan K

更新日期：2009-11-01 00:00:00

abstract：:Cardiovascular disorders are the leading causes of mortality and morbidity in the developed world. Cell-based modalities have received considerable scientific attention over the last decade for their potential use in this clinical arena. This review was intended as a brief overview on the subject of therapeutic potent...

journal_title：Artificial organs

authors： Akar AR,Durdu S,Corapcioglu T,Ozyurda U

更新日期：2006-04-01 00:00:00

abstract：:Centrifugal pumps are generally employed as nonpulsatile blood flow pumps; however, these pumps can produce pulsatile flow by periodically alternating the impeller rotation speed. This study investigates blood trauma due to the effect of pulse frequency and various ranges of pump speed. The hemolysis tests were conduc...

journal_title：Artificial organs

authors： Tayama E,Niimi Y,Takami Y,Ohashi Y,Ohtsuka G,Glueck JA,Mueller J,Nosé Y

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:Lung infection (LI) often occurs in patients with liver transplantation (LT). This meta-analysis was conducted to determine the risk factors associated with LI after LT. METHODS:We retrieved relevant research published as of February 2020 from 8 electronic databases. The studieswere reviewed against the incl...

journal_title：Artificial organs

authors： Zhang J,He Q,Du L,Ji R,Yuan L,Zhang H,Yuan X,Shen L,Li Y

更新日期：2020-09-26 00:00:00

abstract：:A relative contraindication to intermittent peritoneal dialysis (IPD) is chronic lung disease. To evaluate whether the instillation of 2 L of fluid into the peritoneal cavity affects respiratory function, five IPD patients were studied in the supine position during the first 4 h of a routine IPD session. Blood gas ten...

journal_title：Artificial organs

authors： Korzets Z,Pomeranz A,Shachor Y,Bernheim J

更新日期：1988-06-01 00:00:00

abstract：:Effect of hemodialysis (HD) on some indices of immune response was studied in nine chronic uremics. Total lymphocyte, OKT4+, and OKT8+ cell numbers significantly decreased during the first 20 min of HD, and they were decreased till the third hour of the procedure, whereas the OKT4+/OKT8+ cell number ratio did not chan...

journal_title：Artificial organs

authors： Tchórzewski H,Luciak M,Trznadel K,Majewska E,Pokoca L

更新日期：1989-06-01 00:00:00