Bulk mass transport limitations during high-flux hemodialysis.

abstract：:The purified water supplies and randomly selected dialysates of 51 chronic and acute dialysis centers in the central United States were surveyed to assess the relative risks to dialysis patients from microbial and endotoxin contamination. A culture medium more sensitive than those generally employed in routine quality...

journal_title：Artificial organs

authors： Klein E,Pass T,Harding GB,Wright R,Million C

更新日期：1990-04-01 00:00:00

abstract：:Molecular Adsorbent Recirculating System (MARS) is a liver support system widely employed in the treatment of liver failure. The method is normally well tolerated. To develop a liver support system combining high efficiency and tolerability, we modified the MARS albumin circuit with the insertion of double adsorption ...

journal_title：Artificial organs

authors： Marangoni R,Bellati G,Castelli A,Romagnoli E

更新日期：2014-10-01 00:00:00

abstract：:The on-line measurement during hemodialysis of ionic dialysance provides an estimation of urea clearance with a good and already proven correlation. Some discrepancies remain controversial, and the influence of the dialyzer membrane is still being debated. Eighty-eight measurements of ionic dialysance (ID) were perfor...

journal_title：Artificial organs

authors： Mercadal L,Petitclerc T,Jaudon MC,Béné B,Goux N,Jacobs C

更新日期：1998-12-01 00:00:00

abstract：:We compared in vitro rates of hemolysis for a recently developed centrifugal pump with a conventional roller pump (10-10-00; Stöckert, Munich, Germany). Flow rates of 0.3 L/min and 1 L/min and a pressure of 200 mm Hg were chosen to simulate conditions during neonatal extracorporeal membrane oxygenation (ECMO). There w...

journal_title：Artificial organs

authors： Moon YS,Ohtsubo S,Gomez MR,Moon JK,Nose Y

更新日期：1996-05-01 00:00:00

abstract：:Interest in the effects and possible mechanisms of hemodialysis on schizophrenic patients has led to a double-blind evaluation of the effects of plasmapheresis on symptoms of schizophrenia. Also, plasmapheresis was felt to be an invaluable tool for investigating the autoimmune theory of schizophrenia. Patients (n = 10...

journal_title：Artificial organs

authors： Schulz SC,van Kammen DP,Waters R,Klein HG,Balow JE,Bunney WE Jr

更新日期：1983-08-01 00:00:00

abstract：:The heparin-conjugated fibrin (HCF) system has been developed to deliver bone morphogenetic proteins (BMPs) for a long-term period and thus enhance bone regeneration. In the present study, we tested the effectiveness of the delivery system for spinal fusion with a very low dose of BMP-2. A total of 15 rabbits underwen...

journal_title：Artificial organs

authors： Koo KH,Lee JM,Ahn JM,Kim BS,La WG,Kim CS,Im GI

更新日期：2013-05-01 00:00:00

abstract：:Extracorporeal membrane oxygenation (ECMO) has long been the sole means of mechanical support for pediatric patients with end-stage cardiac failure, but has a high waitlist mortality and a reported survival to hospital discharge of less than 50%. The purpose of this study was to compare waitlist mortality and survival...

journal_title：Artificial organs

authors： Jeewa A,Manlhiot C,McCrindle BW,Van Arsdell G,Humpl T,Dipchand AI

更新日期：2010-12-01 00:00:00

abstract：:Hypotension is an uncommon complication of procedures involving extracorporeal circulation, including plasmapheresis. From November 1993 to March 1999, we treated 139 patients who underwent a total of 1,137 sessions of double filtration plasmapheresis (DFP). Hypotension was defined as a systolic blood pressure (BP) < ...

journal_title：Artificial organs

authors： Yeh JH,Chiu HC

更新日期：2000-09-01 00:00:00

abstract：:With the goal of investigating artificial proprioception elicited by electrical stimulation, we have developed a tactile phi phenomenon-based stimulator. This two-channel microprocessed pulse amplitude modulation system generates two different envelope waveforms (triangular and elliptical) and allows programming and v...

journal_title：Artificial organs

authors： Nohama P,Lopes AV,Cliquet Júnior A

更新日期：1995-03-01 00:00:00

abstract：:Possible routes for water and salt flow and the most likely theories that describe coupling between water and salt flow across leaky epithelia are presented. The osmotic theories seem the most likely ones. However, several of the theories have weaknesses that render them unsatisfactory, in particular because of the po...

journal_title：Artificial organs

authors： Whittembury G,Carpi-Medina P,González E,Linares H

更新日期：1987-12-01 00:00:00

abstract：:Midsize molecule retention is related with renal-failure-associated mortality. Here, the authors describe a new dialysis modality, pulse push/pull hemodialysis (PPPHD), which increases convective clearance. Blood and dialysate are circulated by a pulsatile pump, but with pulsatile flow patterns that are 180 degrees ou...

journal_title：Artificial organs

authors： Lee K,Lee SR,Mun CH,Min BG

更新日期：2008-05-01 00:00:00

abstract：:To perform the first experimental tests for validation of a new gear unit concept, the pump chamber, diaphragm, and pusher plate design of an orthotopic electromechanical total artificial heart (TAH) (Helmholtz Labtype) was manufactured. In its early stage of development, it provides some of the most important feature...

journal_title：Artificial organs

authors： Kaufmann R,Reul H,Rau G

更新日期：1994-07-01 00:00:00

abstract：:For the development of a totally implantable ventricular assist system (VAS), we have been developing the vibrating flow pump (VFP), which can generate oscillated blood flow with a relative high frequency (10-50 Hz) for a totally implantable system. In this study, the effects of left ventricular assistance with this u...

journal_title：Artificial organs

authors： Nitta S,Yambe T,Kobayashi S,Hashimoto H,Yoshizawa M,Mastuki H,Tabayashi K,Takeda H

更新日期：1999-01-01 00:00:00

abstract：:The multi-output adaptive controller of a left ventricular assist device (LVAD) was studied by computer simulation. The controller regulated two outputs--mean aortic pressure (mAoP) and mean atrial pressure (mLAP)--by regulating vacuum pressure (input). The autoregressive models were used to describe the circulatory s...

journal_title：Artificial organs

authors： Shimooka T,Mitamura Y,Yuhta T

更新日期：1991-04-01 00:00:00

abstract：:Renal Solutions Allient Sorbent Hemodialysis System utilizes a two-chambered pneumatic pump (Pulsar Blood Pump, Renal Solutions, Inc., Warrendale, PA, USA) to avoid limitations associated with peristaltic pumping systems. Single-needle access is enabled by counter-pulsing the two pump chambers, thereby obviating compl...

journal_title：Artificial organs

authors： Shu F,Parks R,Maholtz J,Ash S,Antaki JF

更新日期：2009-04-01 00:00:00

abstract：:Over a 4 year period, five of 98 patients at our dialysis unit developed signs and symptoms consistent with first-use syndrome (FUS). Marked improvement was noted after subjecting new dialyzers to automated processing using either formaldehyde or peracetic acid. No episodes of FUS occurred in patients being treated wi...

journal_title：Artificial organs

authors： Vanholder R,Ringoir S

更新日期：1987-04-01 00:00:00

abstract：:Many types of rotary blood pumps and pump control methods have recently been developed with the goal of clinical use. From experiments, we know that pump flow spontaneously increases during exercise without changing pump control parameters. The purpose of this study was to determine the hemodynamics associated with th...

journal_title：Artificial organs

authors： Akimoto T,Yamazaki K,Litwak P,Litwak KN,Tagusari O,Mori T,Antaki JF,Kameneva MV,Watach MJ,Umezu M,Tomioka J,Kormos RL,Koyanagi H,Griffith BP

更新日期：1999-08-01 00:00:00

abstract：:Artificial cells are prepared in the laboratory for medical and biotechnological applications. Encapsulated cells are being studied for the treatment of diabetes, liver failure, and other conditions. More recently, there have been extensive studies into the use of encapsulated genetically engineered cells for gene the...

journal_title：Artificial organs

authors： Chang TM

更新日期：1998-11-01 00:00:00

abstract：PURPOSE:We were led to the premise that with retrograde oxygenated blood perfusion, it would be possible to perform operations on the beating heart. METHODS:The experiment consisted of two stages: procedure 1 and 2. In procedure 1, six pigs were used. Retrograde perfusion flow was controlled to be in the range of 5.0-...

journal_title：Artificial organs

authors： Tsukioka T,Tomita S,Watanabe G,Takemura H

更新日期：2004-03-01 00:00:00

abstract：:Over the past several years, we have developed novel titanium-niobium-zirconium (Ti-Nb-Zr) alloys to address the long-term performance needs of orthopedic implants. The unique properties of these alloys also render them promising candidates for blood pumps. These properties include excellent biocompatibility in combin...

journal_title：Artificial organs

authors： Davidson JA,Daigle KP,Kovacs P

更新日期：1996-05-01 00:00:00

abstract：:Small-caliber decellularized xenografts with surface heparin coating are known to reduce in vivo thrombogenicity. This study was performed to examine whether heparin coating on the small-caliber decellularized xenografts would reduce macrophage infiltration and intimal hyperplasia. In a rabbit model of bilateral carot...

journal_title：Artificial organs

authors： Cai WW,Gu YJ,Wang XN,Chen CZ

更新日期：2009-06-01 00:00:00

abstract：:Traumatic injury is often associated with hemorrhagic shock. Liposome-encapsulated hemoglobin (LEH) is being developed as an artificial oxygen carrier to address post-hemorrhage oxygen and volume deficit. Here, we report a new composition of LEH based on the use of polyethylene glycol (PEG2K ) conjugated with nonphosp...

journal_title：Artificial organs

authors： Yadav VR,Nag O,Awasthi V

更新日期：2014-08-01 00:00:00

abstract：:This article introduces a unique miniaturization process of a magnetically levitated axial flow blood pump from a functional prototype to a pump suitable for animal trials. Through COMSOL three-dimensional finite element analysis and experimental verification, the hybrid magnetic bearings of the pump have been miniatu...

journal_title：Artificial organs

authors： Cheng S,Olles MW,Olsen DB,Joyce LD,Day SW

更新日期：2010-10-01 00:00:00

abstract：:Planar particle image velocimetry was used to explore the flow behavior of the newly designed 12-cc Penn State pneumatic pediatric assist pump. Wall shear maps complemented the velocity data. Bjork-Shiley Monostrut 17-mm mechanical heart valves were used in the inlet and outlet ports. In comparison with larger Penn St...

journal_title：Artificial organs

authors： Manning KB,Wivholm BD,Yang N,Fontaine AA,Deutsch S

更新日期：2008-06-01 00:00:00

abstract：:This study evaluated the usefulness of the three-dimensional representation of electrocardiogram traces (3DECG) to reveal acute and gradual changes during a full session of hemodiafiltration (HDF) in end-stage renal disease (ESRD) patients. Fifteen ESRD patients were included (six men, nine women, age 46 ± 19 years ol...

journal_title：Artificial organs

authors： Rodriguez-Fernandez R,Infante O,Perez-Grovas H,Hernandez E,Ruiz-Palacios P,Franco M,Lerma C

更新日期：2012-06-01 00:00:00

abstract：:Neurological morbidity is a major concern in pediatric cardiac surgery. Cardiopulmonary bypass is one of the few modifiable factors affecting neurodevelopmental outcome. This study aimed to measure the incidence of abnormalities apparent by magnetic resonance imaging (MRI) after neonatal arterial switch operation usin...

journal_title：Artificial organs

authors： Durandy Y,Rubatti M,Couturier R,Rohnean A

更新日期：2011-11-01 00:00:00

abstract：:In this study two aspects of hybrid functional electrical stimulation (FES) orthoses were investigated: joint motion constraints and FES control strategies. First, the effects of joint motion constraints on the gait of normal subjects were investigated using modern motion analysis systems, including electromyogram (EM...

journal_title：Artificial organs

authors： Yang L,Granat MH,Paul JP,Condie DN,Rowley DI

更新日期：1997-03-01 00:00:00

abstract：:A microcapsule suspension, a substitute for animal blood in hemolysis tests, has been developed for evaluation of the absolute hemolytic properties of circulatory artificial organs. The microcapsule suspension was made by dispersing microcapsule slurry into an ethylene glycol sodium chloride solution. The microcapsule...

journal_title：Artificial organs

authors： Maruyama O,Yamane T,Tsunemoto N,Nishida M,Tsutsui T,Jikuya T

更新日期：1999-03-01 00:00:00

abstract：:The sensitivity of liver allografts to even minimal periods of ischemia currently limits the duration of hepatic preservation prior to liver transplantation. This study evaluates the role of activated carbon hemoperfusion (ACH) for assisting the recovery of canine livers ischemically damaged by a 20-min occlusion of t...

journal_title：Artificial organs

authors： Toledo-Pereyra LH

更新日期：1985-08-01 00:00:00

abstract：:Veno-arterial extracorporeal membrane oxygenation (ECMO) may be implanted using peripheral ECMO (pECMO) or central ECMO (cECMO) cannulation techniques. The aim of this study was to compare the outcome between these two cannulation techniques. A retrospective study was performed at Düsseldorf University Hospital from O...

journal_title：Artificial organs

authors： Saeed D,Stosik H,Islamovic M,Albert A,Kamiya H,Maxhera B,Lichtenberg A

更新日期：2014-07-01 00:00:00