Wear-Resistant, Hemocompatible Ti-Nb-Zr and Zr-Nb Alloys to Improve Blood Pump Design and Performance.

abstract：:The major problems with existing centrifugal pumps are leakage, mechanical trauma, and thrombus formation. In consideration of these problems, a new compact centrifugal pump system was developed. The purpose of this study was to evaluate the new centrifugal pump system clinically. Ten patients underwent open heart sur...

journal_title：Artificial organs

authors： Ninomiya J,Shoji T,Tanaka S,Ikeshita M,Ochi M,Yamauchi S,Yajima T,Yamauchi H,Sugimoto T,Aizawa T

更新日期：1994-09-01 00:00:00

abstract：:Cell-contracted collagen gels could provide rejection-free biomaterials for tissue engineering, but their application is limited by relatively low mechanical strength. We developed a special type I collagen construct (based on embedded fibroblasts) that was formed into a gel thread by using two anchors to constrain ge...

journal_title：Artificial organs

authors： Feng Z,Ishibashi M,Nomura Y,Kitajima T,Nakamura T

更新日期：2006-11-01 00:00:00

abstract：:Infusion into rats of the polycation hexadimethrine (HDM) leads to onset of massive proteinuria, which recovers when the infusion is stopped. Several lines of evidence indicate that the proteinuria results from binding of HDM to polyanions of the glomerular filter, with neutralization of shielding of their charges. To...

journal_title：Artificial organs

authors： Hunsicker LG,Bertolatus JA

更新日期：1987-12-01 00:00:00

abstract：:A compact three-dimensional (3D) module is needed for hepatocyte culture in order to develop an effective hybrid artificial liver system that can retain hepatocellular structure and differentiated functions. We treated the 3D module with collagen gel to entrap rat hepatocytes. This method yielded a high hepatocellular...

journal_title：Artificial organs

authors： Takeshita K,Ishibashi H,Suzuki M,Yamamoto T,Akaike T,Kodama M

更新日期：1995-02-01 00:00:00

abstract：:Patients with kidney failure can only survive with some form of kidney replacement (transplant or dialysis). Unfortunately, innovations in kidney replacement therapy lag behind many other medical fields. This study compiles expert opinions on candidate technologies for future kidney replacement therapies. A worldwide ...

journal_title：Artificial organs

authors： Pereira Cabral B,Bonventre JV,Wieringa F,Mota FB

更新日期：2020-07-22 00:00:00

abstract：:Long-term hemodialysis catheter dwell time in the central vein predisposes to fibrin sheath development, which subsequently causes catheter malfunction or occlusion. In very rare cases, the catheter can be overgrown with fibrin and rigidly connected with the vein or heart structures. This makes its removal almost impo...

journal_title：Artificial organs

authors： Garcarek J,Gołębiowski T,Letachowicz K,Kusztal M,Szymczak M,Madziarska K,Jakuszko K,Zmonarski S,Guziński M,Weyde W,Klinger M

更新日期：2016-05-01 00:00:00

abstract：:From January 1980 through December 1990, implantation of a permanent pacemaker was performed in 34 patients following open heart surgery. The patients were divided into two groups according to the clinical indications for implantation of permanent pacemakers. Group 1 (9 patients) had surgical atrioventricular block, a...

journal_title：Artificial organs

authors： Otaki M

更新日期：1993-05-01 00:00:00

abstract：:The optimization of the monomer composition, using a polymerization kinetic study and the mechanical behavior study of the composites, was the principal objective of this work. The monomeric mixture analyzed is a part of the composite that has been in development at the University of Campinas, Brazil. Parameters such ...

journal_title：Artificial organs

authors： López Palacio RE,de Carvalho Zavaglia CA

更新日期：2003-05-01 00:00:00

abstract：:A 36-year-old female was treated successfully by hemoperfusion over Amberlite XAD-4 resin after ingestion of 40 gm of meprobamate. Hemoperfusion was started five hours after the ingestion. At that time the patient was in deep coma. The patient was treated by hemoperfusion for five hours, at the end of which time she w...

journal_title：Artificial organs

authors： Freund LG

更新日期：1981-02-01 00:00:00

abstract：:This article presents computational studies on the effects of inlet guide vanes (IGVs) on the flow pattern and shear stress in a centrifugal blood pump. The effect of IGVs is to introduce a pre-swirl to fluid particles entering the impeller with the intention that the fluid particles will travel along the blade profil...

journal_title：Artificial organs

authors： Chan WK,Wong YW,Yu SC,Chua LP

更新日期：2002-06-01 00:00:00

abstract：:Cardiomyoplasty has been proposed as an alternative surgical treatment for congestive heart failure. The girdling effect of the muscle wrap is believed to reduce diastolic wall stress. We tested the hypothesis that nonstimulated or passive cardiomyoplasty (CDM) would reduce hemodynamic deficits in rats with experiment...

journal_title：Artificial organs

authors： De Angelis K,Leirner AA,Irigoyen MC,Cestari IA

更新日期：2001-11-01 00:00:00

abstract：:The majority of cases involving the surgical treatment of congenital heart disease require implementation of cardiopulmonary bypass (CPB). However, neonates and infants are particularly prone to serious complications associated with CPB as a result of capillary leak due to cardiovascular failure. These complications a...

journal_title：Artificial organs

authors： Schnoering H,Arens J,Detering SM,Sachweh JS,Goetzenich A,Schmitz-Rode T,Steinseifer U,Vazquez-Jimenez JF

更新日期：2013-06-01 00:00:00

abstract：:A totally implantable centrifugal artificial heart has been developed in which a pivot bearing supported centrifugal pump is used as a blood pump. The following have been adopted as blood contacting materials in our pump: titanium alloy (Ti-6A1-4V) for the housing and impeller, alumina ceramic (Al2O3) for the male piv...

journal_title：Artificial organs

authors： Takami Y,Yamane S,Makinouchi K,Niimi Y,Sueoka A,Nosé Y

更新日期：1998-09-01 00:00:00

abstract：:Extracorporeal membrane oxygenation (ECMO) is gaining importance in the perioperative management of lung transplant patients. To date, the ideal substance for anticoagulation of ECMO patients is still a matter of debate. In this study, we describe our experience with the use of low molecular weight heparin (LMWH) in c...

journal_title：Artificial organs

authors： Gratz J,Pausch A,Schaden E,Baierl A,Jaksch P,Erhart F,Hoetzenecker K,Wiegele M

更新日期：2020-06-01 00:00:00

abstract：:In this study, we have developed an implantable electronics unit (IEU) for driving an undulation pump-left ventricular assist device (UP-LVAD). The IEU consists of a pump driver, three series-connected lithium ion batteries (1800 mAh), a charger, and a transcutaneous information transmission system. These electronic s...

journal_title：Artificial organs

authors： Okamoto E,Makino T,Inoue Y,Tanaka S,Yasuda T,Nakamura M,Saito I,Abe Y,Chinzei T,Isoyama T,Mochiizuki S,Imachi K,Mitamura Y

更新日期：2006-05-01 00:00:00

abstract：:The Fas molecule, also designated APO-1/CD95, belongs to the tumor necrosis factor (TNF) receptor family. It is a widely expressed membrane-anchored protein that induces apoptosis by Fas/Fas ligand (Fas-L) mediation. It was reported that Fas-mediated apoptosis plays an important role in regulation of the immune system...

journal_title：Artificial organs

authors： Kawahito K,Misawa Y,Fuse K

更新日期：2000-08-01 00:00:00

abstract：:Ten dialysis patients were followed in a prospective study to determine the neurotoxicity of metabolites in the middle molecule (MM) molecular weight (mol wt) range of 500-200 daltons/molecule. In the absence of readily available direct serum measurements of MM concentrations, a theoretically calculated dialysis index...

journal_title：Artificial organs

authors： Milutinovic J,Babb AL,Eschbach JW,Follette WC,Graefe U,Strand MJ,Scribner BH

更新日期：1978-02-01 00:00:00

abstract：:The development of a ventricular assist device is depicted. The seven subprograms that make up the project are described briefly. Results obtained during the clinical assay showed that the new design of the input cannula working as a false auricle provides better efficiency, as well as a certain level of autoregulatio...

journal_title：Artificial organs

authors： del Cañizo JF,Antoranz JC,Desco MM,Alvarez-Valdivielso JM,Fernandez-Caleya D,López M,Garcia-Barreno P,Duarte J

更新日期：1994-07-01 00:00:00

abstract：:Sponge-type small-diameter vascular grafts were fabricated from a medical-grade polyurethane, Pellethane 2363-80A, by utilization of a salt casting technique. The grafts were compliance matched with a storage modulus of 0.53 +/- 0.08 MPa. The luminal surface of grafts was modified with a thin layer ( approximately 40 ...

journal_title：Artificial organs

authors： Hsu SH,Sun SH,Chen DC

更新日期：2003-12-01 00:00:00

abstract：:The aim of this work is to construct a computational fluid dynamics model capable of simulating the transient non-Newtonian process of apheresis. A Lagrangian-Eulerian model has been developed which tracks the blood particles within a two-dimensional flow configuration. Within the Eulerian method, the fluid mass and m...

journal_title：Artificial organs

authors： De Gruttola S,Boomsma K,Poulikakos D

更新日期：2005-12-01 00:00:00

abstract：:The characteristic depressed hemodynamic state and gradually declining circulatory function in Fontan patients necessitates alternative postoperative management strategies incorporating a system level approach. In this study, the single-ventricle Fontan circulation is modeled by constructing a practical in vitro bench...

journal_title：Artificial organs

authors： Dur O,Lara M,Arnold D,Vandenberghe S,Keller BB,DeGroff C,Pekkan K

更新日期：2009-11-01 00:00:00

abstract：:Magnevad II is an improved version of Magnevad I and both are fourth-generation axial flow left ventricular assist devices. A major simplification has been implemented and tested. Magnevad I used a magnetically suspended rotor requiring active axial control. Magnevad II is completely passive but otherwise similar. A s...

journal_title：Artificial organs

authors： Goldowsky M,Lafaro R,Reed G

更新日期：2005-10-01 00:00:00

abstract：:Microcapsules containing insulin crystals or islets of Langerhans were made by extruding a mixture of insulin crystals or islets and sodium alginate into a calcium chloride solution, and then coating it with poly-l-lysine. When these microcapsules were incubated at 37 degrees C, insulin could be detected readily in th...

journal_title：Artificial organs

authors： Leung YF,O'Shea GM,Goosen MF,Sun AM

更新日期：1983-05-01 00:00:00

abstract：:In order to define physiological properties of the autograft root, magnetic resonance imaging (MRI) findings relative to three different operative techniques were compared with those of control subjects. Twenty-three patients, 18/5 M/F, aged 32 ± 9 years, underwent MRI assessment of the aortic root. Patients with norm...

journal_title：Artificial organs

authors： Luciani GB,Viscardi F,Puppini G,Faggian G,Mazzucco A

更新日期：2011-12-01 00:00:00

abstract：:Proper wound healing can be assessed by monitoring the wound surface area. Its reduction by 10 or 50% should be achieved after 1 or 4 weeks, respectively, from the start of the applied therapy. There are various methods of wound area measurement, which differ in terms of the cost of the devices and their accuracy. Thi...

journal_title：Artificial organs

authors： Foltynski P,Ladyzynski P,Wojcicki JM

更新日期：2014-04-01 00:00:00

abstract：:In a controlled European multicenter study, clinical tolerance of subcutaneously administered recombinant human erythropoietin (rh-EPO) therapy and its influence on the course of illness in 362 hemodialyzed patients (162 males, 200 females) from 16 European dialysis centers was studied. Of these, 181 patients served a...

journal_title：Artificial organs

authors： Klinkmann H,Wieczorek L,Scigalla P

更新日期：1993-04-01 00:00:00

abstract：:Interest in the effects and possible mechanisms of hemodialysis on schizophrenic patients has led to a double-blind evaluation of the effects of plasmapheresis on symptoms of schizophrenia. Also, plasmapheresis was felt to be an invaluable tool for investigating the autoimmune theory of schizophrenia. Patients (n = 10...

journal_title：Artificial organs

authors： Schulz SC,van Kammen DP,Waters R,Klein HG,Balow JE,Bunney WE Jr

更新日期：1983-08-01 00:00:00

abstract：:The determination of when to stop extracorporeal membrane oxygenation (ECMO) rests upon demonstration of the return of adequate cardiac function to support vital organs and permit subsequent recovery. In general, patients with myocardial stun will recover function within several days. Factors that limit recovery inclu...

journal_title：Artificial organs

authors： Steinhorn DM

更新日期：1999-11-01 00:00:00

abstract：:The objective of this study was to evaluate an alternative neonatal extracorporeal life support (ECLS) circuit with a RotaFlow centrifugal pump and Better-Bladder (BB) for hemodynamic performance and gaseous microemboli (GME) capture in a simulated neonatal ECLS system. The circuit consisted of a Maquet RotaFlow centr...

journal_title：Artificial organs

authors： Spencer SB,Wang S,Woitas K,Glass K,Kunselman AR,Ündar A

更新日期：2017-01-01 00:00:00

abstract：:The most common method of controlling acidemia during lung-protective ventilation is CO₂ removal with an extracorporeal lung assist (ECLA) system. Another possibility to prevent acidemia is based on intravenous (i.v.) application of tris-hydroxymethyl-aminomethane (3 mol/L, THAM) buffer, which can bind hydrogen proton...

journal_title：Artificial organs

authors： Russ M,Deja M,Ott S,Bedarf J,Keckel T,Hiebl B,Wagner JJ,Unger JK

更新日期：2011-06-01 00:00:00