Methodology for identification of serum middle molecules.

Abstract:

:Filtration through membranes with different nominal cut-off was used for isolation of middle molecule fractions from uremic serum. Comparison was made with test substances which in gel filtration did not show a regular relationship between molecular weight and partition coefficient. The XM50 membrane (cut-off 50,000 D) showed the highest permeability to middle molecules (greater than 84%) whereas CF50 (same cut-off) retained middle molecules to some extent if filtration was carried out only once. The UM05 membrane (cut-off 500 D) was highly permeable for small molecules less than 300 D, intermediary permeable for molecules between 300 and 1000 D and retained molecules between 1,100 and 1,350 D more efficiently. It is concluded that filtration through membranes is a suitable method for identification of middle molecules.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Buzio C,Montagna G,Calderini C,Manari A,Migone L

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

22-7

eissn

0160-564X

issn

1525-1594

journal_volume

4 Suppl

pub_type

杂志文章
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    doi:10.1111/j.1525-1594.1987.tb02713.x

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  • Simple evaluation method of biocompatibility of artificial oxygenator hollow fiber.

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    journal_title:Artificial organs

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    更新日期:1996-12-01 00:00:00

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    pub_type: 杂志文章

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    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1996.tb04507.x

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  • Bioengineered cartilage in a scaffold-free method by human cartilage-derived progenitor cells: a comparison with human adipose-derived mesenchymal stromal cells.

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  • Is low-intensity anticoagulant therapy possible with an open pivot valve?: analysis of its development.

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  • Noninvasive average flow estimation for an implantable rotary blood pump: a new algorithm incorporating the role of blood viscosity.

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    doi:10.1111/j.1525-1594.2007.00339.x

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  • A reduced priming system.

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  • Further development of hybrid functional electrical stimulation orthoses.

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  • Balloon Dilatation for Removal of an Irretrievable Permanent Hemodialysis Catheter: The Safest Approach.

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    pub_type: 杂志文章

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  • Heart valve inspired and multi-stream aortic cannula: Novel designs for cardiopulmonary bypass improvement in neonates.

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  • Oxidative Stress Increases Erythrocyte Sensitivity to Shear-Mediated Damage.

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