Abstract:
:The introduction of highly active antiretroviral therapy (HAART) has significantly modified the course of human immunodeficiency virus (HIV) disease, with longer survival and improved quality of life of HIV-infected subjects. However, HAART regimens, especially those including protease inhibitors, have been shown to cause in a high proportion of HIV-infected patients a metabolic syndrome (lipodystrophy/lipoatrophy, dyslipidemia, type 2 diabetes mellitus, insulin resistance) that may be associated with an increased risk of cardiovascular disease (coronary artery disease and stroke). A careful stratification of the cardiovascular risk and cardiovascular monitoring of patients under HAART is needed according to the most recent clinical guidelines.
journal_name
Chemotherapyjournal_title
Chemotherapyauthors
Barbaro G,Barbarini Gdoi
10.1159/000093034subject
Has Abstractpub_date
2006-01-01 00:00:00pages
161-5issue
4eissn
0009-3157issn
1421-9794pii
93034journal_volume
52pub_type
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