Abstract:
BACKGROUND:Enterococci and especially glycopeptide-resistant strains (GRE) are widely distributed in the hospital environment, by acquiring resistance determinants and virulence factors. METHODS:The study included 48 GRE isolated during a 1-year period from different inpatients in a tertiary hospital in southwestern Greece. Antibiotic susceptibility was determined by the Etest, and the presence of resistance and virulence genes was shown by PCR. Clonal types were identified by pulsed-field gel electrophoresis of SmaI DNA digests. RESULTS:All GRE were multi-resistant of the VanA phenotype, verified by the detection of the gene by PCR. Two major clones were distributed in all hospital wards. The majority of the strains (46 of 48) harbored the esp gene, while 27 GRE expressed also the gelE and/or as genes. CONCLUSIONS:The spread of two clones expressing the vanA gene and virulence factors were responsible for the emergence of GRE in the University Hospital of Patras.
journal_name
Chemotherapyjournal_title
Chemotherapyauthors
Kolonitsiou F,Mani V,Parikou H,Trakala M,Dimitracopoulos G,Spiliopoulou Idoi
10.1159/000081945subject
Has Abstractpub_date
2004-11-01 00:00:00pages
245-9issue
5eissn
0009-3157issn
1421-9794pii
81945journal_volume
50pub_type
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