Abstract:
:Combination of 9-(S)-(2,3-dihydroxypropyl)adenine [(S)-DHPA] and 6-azauridine (AzUrd) is highly active in the selective inhibition of vaccinia virus in chick embryo cell culture. Synergic effect of this combination of compounds was not encountered in HeLa cell culture. Of the 17 analogues related to DHPA studied in this paper, 3 showed medium activity against vaccinia virus, but none of them was as effective as (S)-DHPA in combination with AzUrd.
journal_name
Chemotherapyjournal_title
Chemotherapyauthors
Rada B,Holý Adoi
10.1159/000237903subject
Has Abstractpub_date
1980-01-01 00:00:00pages
184-90issue
3eissn
0009-3157issn
1421-9794journal_volume
26pub_type
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