Abstract:
:We conducted a retrospective clinical evaluation to assess the efficacy of a 1-gram once-daily regimen of intravenously administered ceftriaxone in the treatment of a variety of bacterial infections. Of the 250 patients studied, 167 had infections of the lower respiratory tract, approximately 70% of which were diagnosed as community-acquired pneumonias. The principal identified pathogens were Staphylococcus aureus and Haemophilus influenzae. Forty per cent of community-acquired pneumonias occurred in patients over 69 years of age, who showed a 13% mortality compared to a mortality rate of 4% in younger patients. Once-daily ceftriaxone was effective and well tolerated as empiric therapy for pneumonia likely to be caused by susceptible organisms.
journal_name
Chemotherapyjournal_title
Chemotherapyauthors
Brown Rdoi
10.1159/000238927subject
Has Abstractpub_date
1991-01-01 00:00:00pages
11-4eissn
0009-3157issn
1421-9794journal_volume
37 Suppl 3pub_type
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