Once-daily ceftriaxone in the treatment of lower respiratory tract infections.

Abstract:

:We conducted a retrospective clinical evaluation to assess the efficacy of a 1-gram once-daily regimen of intravenously administered ceftriaxone in the treatment of a variety of bacterial infections. Of the 250 patients studied, 167 had infections of the lower respiratory tract, approximately 70% of which were diagnosed as community-acquired pneumonias. The principal identified pathogens were Staphylococcus aureus and Haemophilus influenzae. Forty per cent of community-acquired pneumonias occurred in patients over 69 years of age, who showed a 13% mortality compared to a mortality rate of 4% in younger patients. Once-daily ceftriaxone was effective and well tolerated as empiric therapy for pneumonia likely to be caused by susceptible organisms.

journal_name

Chemotherapy

journal_title

Chemotherapy

authors

Brown R

doi

10.1159/000238927

subject

Has Abstract

pub_date

1991-01-01 00:00:00

pages

11-4

eissn

0009-3157

issn

1421-9794

journal_volume

37 Suppl 3

pub_type

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