Recombinant-inbred strains: general methodological considerations relevant to the study of complex characters.

abstract：:To study the relationship between genetics and epilepsy, Wistar rats susceptible to audiogenic seizure were selected from the main breeding stock of the Ribeirão Preto School of Medicine at the University of São Paulo, Brazil, and inbred. The criteria for selection were the highest seizure severity index (SI) and shor...

journal_title：Behavior genetics

authors： Doretto MC,Fonseca CG,Lôbo RB,Terra VC,Oliveira JA,Garcia-Cairasco N

更新日期：2003-01-01 00:00:00

abstract：:A wealth of literature suggests that normative and heavy alcohol consumption continue to follow a historical pattern of greater prevalence among males as compared to females. Some prior research suggested that sex-specific factors might explain some of this gender gap. Generally speaking, though, more recent studies h...

journal_title：Behavior genetics

authors： Richardson GB,Boutwell BB

更新日期：2020-09-01 00:00:00

abstract：:Effective mapping strategies for quantitative trains must allow for the detection of the more important quantitative trait loci (QTLs) while minimizing false positives. Type I (false-positive) and Type II (false-negative) error rates were estimated from a computer simulation of QTL mapping in the BXD recombinant inbre...

journal_title：Behavior genetics

authors： Belknap JK,Mitchell SR,O'Toole LA,Helms ML,Crabbe JC

更新日期：1996-03-01 00:00:00

abstract：:A powerful longitudinal data source, the National Longitudinal Survey of Youth Children data, allows measurement of behavior problems (BP) within a developmental perspective linking them to menarcheal timing (MT). In a preliminary analysis, we evaluate the bivariate relationships between BP measured at different devel...

journal_title：Behavior genetics

authors： Rodgers JL,Van Hulle C,D'Onofrio B,Rathouz P,Beasley W,Johnson A,Waldman I,Lahey BB

更新日期：2015-01-01 00:00:00

abstract：:In the present study we evaluated long term memory in twenty individuals with molecularly confirmed diagnosis of Noonan syndrome and LEOPARD syndrome, two disorders caused by mutations in genes coding transducers participating in the RAS-MAPK signaling cascade. The profile of explicit long term memory abilities was in...

journal_title：Behavior genetics

authors： Alfieri P,Cesarini L,Mallardi M,Piccini G,Caciolo C,Leoni C,Mirante N,Pantaleoni F,Digilio MC,Gambardella ML,Tartaglia M,Vicari S,Mercuri E,Zampino G

更新日期：2011-05-01 00:00:00

abstract：:Social aggregations of free-ranging cattle were studied in the Sonoran Desert of Mexico. Cows reared with animals of their own breed in isolation from other breeds maintained segregated social groups. Cows raised together in a mixed herd containing other breeds allied themselves with herd-mates regardless of breed. Ca...

journal_title：Behavior genetics

authors： Murphey RM

更新日期：1990-05-01 00:00:00

abstract：:Differences between population-typical norms of individual variability were studied in five genetic lines of Japanese quail (Coturnix coturnix japonica); two (BL and RL) were bidirectionally selected for early approach preference between blue and red stimuli, two (Hi and Lo) for high and low imprintabilities to the sa...

journal_title：Behavior genetics

authors： Kovach JK

更新日期：1992-09-01 00:00:00

abstract：:This study uses longitudinal population-based samples of young siblings to examine the effects of two hypothesized moderators of early externalizing behaviors: parental emotional support and family socioeconomic status. The first sample, a twin sample from the Early Childhood Longitudinal Study-Birth Cohort (ECLS-B), ...

journal_title：Behavior genetics

authors： Cheung AK,Harden KP,Tucker-Drob EM

更新日期：2014-09-01 00:00:00

abstract：:Biometric studies have shown that happiness is strongly affected by genes. The findings are mainly based on twin data, however, and the full validity of the results has been debated. To overcome some limitations in classical twin research, we examined aetiological sources of subjective well-being (SWB), using two inde...

journal_title：Behavior genetics

authors： Nes RB,Czajkowski N,Tambs K

更新日期：2010-09-01 00:00:00

abstract：:Genomewide scan, as shown by recently published linkage studies on the behavior of mice or in psychiatry, provides evidence for replicated quantitative trait loci (QTL). Several studies of Alzheimer's disease have demonstrated the promise of moving from clinical diagnoses to biological signs for psychiatric investigat...

journal_title：Behavior genetics

authors： Roubertoux PL,Le Roy-Duflos I

更新日期：2001-01-01 00:00:00

abstract：:We review the literature on the familial resemblance of body mass index (BMI) and other adiposity measures and find strikingly convergent results for a variety of relationships. Results from twin studies suggest that genetic factors explain 50 to 90% of the variance in BMI. Family studies generally report estimates of...

journal_title：Behavior genetics

authors： Maes HH,Neale MC,Eaves LJ

更新日期：1997-07-01 00:00:00

abstract：:Alterations of peripheral magnesium (Mg) concentration have been reported in association with several behavioral disorders and sleep organization. Blood Mg regulation is under a strong genetic control, whereas brain Mg regulation does not seem to be affected. We have studied peripheral and central levels of Mg and ana...

journal_title：Behavior genetics

authors： Chollet D,Franken P,Raffin Y,Henrotte JG,Widmer J,Malafosse A,Tafti M

更新日期：2001-09-01 00:00:00

abstract：:Extreme sampling of sibling pairs has been shown to be efficient in terms of statistical power and sample sizes (in number of sibling pairs needed to genotype) to detect a quantitative trait locus (QTL) when the residual distribution is normal. In the present study, the efficiency of extreme sampling strategies to det...

journal_title：Behavior genetics

authors： Heo M,Faith MS,Allison DB

更新日期：2002-01-01 00:00:00

abstract：:In an investigation into the effects of developmental isolation from all conspecifics, the Drosophila willistoni group of six sibling species responded to differing degrees: all six are reproductively isolated from D. paulistorum, the tester species. Drosophila pavlovskiana, a narrow endemic, proved the most vulnerabl...

journal_title：Behavior genetics

authors： Kim YK,Ehrman L

更新日期：1999-01-01 00:00:00

abstract：:Almost 40 years ago, evidence from large studies of adult twins and their relatives suggested that between 30 and 60% of the variance in social and political attitudes could be explained by genetic influences. However, these findings have not been widely accepted or incorporated into the dominant paradigms that explai...

journal_title：Behavior genetics

authors： Hatemi PK,Medland SE,Klemmensen R,Oskarsson S,Littvay L,Dawes CT,Verhulst B,McDermott R,Nørgaard AS,Klofstad CA,Christensen K,Johannesson M,Magnusson PK,Eaves LJ,Martin NG

更新日期：2014-05-01 00:00:00

abstract：:The zebrafish enjoys several advantages over other model organisms. It is small, easy to maintain, prolific, and numerous genetic tools are available for it. For example, forward genetic screens have allowed investigators to identify important genes potentially involved in a variety of functions from embryogenesis to ...

journal_title：Behavior genetics

authors： Gerlai R,Poshusta TL,Rampersad M,Fernandes Y,Greenwood TM,Cousin MA,Klee EW,Clark KJ

更新日期：2017-01-01 00:00:00

abstract：:We examined data from a large cohort of homosexual and heterosexual females and males concerning their siblings' sexual orientations. As in previous studies, both male and female homosexuality were familial. Homosexual females had an excess of homosexual brothers compared to heterosexual subjects, thus providing evide...

journal_title：Behavior genetics

authors： Bailey JM,Bell AP

更新日期：1993-07-01 00:00:00

abstract：:Tested in Hirsch-Hadler mazes, Drosophila pseudoobscura is on the average geoneutral and photoneutral. Strongly geo- and photopositive and geo- and photonegative populations can be obtained by artificial selection, but upon relaxation of the selection they tend to relapse toward neutrality. This genetic homeostasis is...

journal_title：Behavior genetics

authors： Levene H,Dobzhansky T

更新日期：1976-07-01 00:00:00

abstract：:Gender-moderated gene-environment interactions are rarely explored, raising concerns about inaccurate specification of etiological models and inferential errors. The current study examined the influence of gender, negative and positive daily life events, and GABRA2 genotype (SNP rs279871) on alcohol dependence, testin...

journal_title：Behavior genetics

authors： Perry BL,Pescosolido BA,Bucholz K,Edenberg H,Kramer J,Kuperman S,Schuckit MA,Nurnberger JI Jr

更新日期：2013-09-01 00:00:00

abstract：:Complex illnesses, like depression, are thought to arise from the interplay between psychosocial stressors and genetic predispositions. Approaches that take into account both personal and neighborhood factors and that consider gene regions as well as individual SNPs may be necessary to capture these interactions acros...

journal_title：Behavior genetics

authors： Ware EB,Smith JA,Mukherjee B,Lee S,Kardia SL,Diez-Roux AV

更新日期：2016-01-01 00:00:00

abstract：:We present a repeated-measures, genetic analysis of ethanol-induced anesthesia (sleep time) in mice from the inbred long-sleep (ILS) and short-sleep (ISS) strains of mice and their derived F1 and F2 generations. Mice (total N > 1300) were administered a 4.1 g/kg intraperitoneal dose of ethanol at two times, 7 to 10 da...

journal_title：Behavior genetics

authors： Markel PD,DeFries JC,Johnson TE

更新日期：1995-01-01 00:00:00

abstract：:Here we provide a detailed description of the genome-wide information available on the National Longitudinal Study of Adolescent to Adult Health (Add Health) sibling pair subsample (Harris et al. in Twin Res Hum Genet 16:391-398, 2013). A total of 2,020 samples were genotyped (including duplicates) arising from 1946 A...

journal_title：Behavior genetics

authors： McQueen MB,Boardman JD,Domingue BW,Smolen A,Tabor J,Killeya-Jones L,Halpern CT,Whitsel EA,Harris KM

更新日期：2015-01-01 00:00:00

abstract：:Selection for geotaxis was carried out with flies from a natural population of Drosophila melanogaster; geotactic behavior was measured by means of a Hirsch classification maze. The population was initally almost neutral to gravity, and it responded to both positive (downward) and negative (upward) selection with a re...

journal_title：Behavior genetics

authors： Watanabe TK,Anderson WW

更新日期：1976-01-01 00:00:00

abstract：:Voluntary physical activity may be related to personality traits. Here, we investigated these relations in two mouse lines selectively bred for high voluntary wheel-running behavior and in one non-selected control line. Selection lines were more explorative and "information gathering" in the open-field test, either wi...

journal_title：Behavior genetics

authors： Jónás I,Schubert KA,Reijne AC,Scholte J,Garland T Jr,Gerkema MP,Scheurink AJ,Nyakas C,van Dijk G

更新日期：2010-07-01 00:00:00

abstract：:The amygdala integrates and coordinates emotional and autonomic responses. The genetics that underlie variation in amygdala structure may be coupled to variation in levels of aggression, fear, anxiety, and affiliated behaviors. We systematically quantified the volume and cell populations of the basolateral amygdala co...

journal_title：Behavior genetics

authors： Mozhui K,Hamre KM,Holmes A,Lu L,Williams RW

更新日期：2007-01-01 00:00:00

abstract：:The non-synonymous SNP rs2228145 in the IL6R gene on chromosome 1q21.3 is associated with a wide range of common diseases, including asthma, rheumatoid arthritis, type 1 diabetes and coronary heart disease. We examined the contribution of this functional IL6R gene polymorphism rs2228145 versus other genome-wide SNPs t...

journal_title：Behavior genetics

authors： van Dongen J,Jansen R,Smit D,Hottenga JJ,Mbarek H,Willemsen G,Kluft C,AAGC Collaborators.,Penninx BW,Ferreira MA,Boomsma DI,de Geus EJ

更新日期：2014-07-01 00:00:00

abstract：:Chickens homozygous for the Dominant white or wild-type allele of PMEL17 were subjected to a broad phenotyping in order to detect consistent differences between genotypes. To exclude feather pecking, the chickens were individually housed without physical contact, from the day of hatching, and tested for social, aggres...

journal_title：Behavior genetics

authors： Karlsson AC,Mormede P,Kerje S,Jensen P

更新日期：2011-03-01 00:00:00

abstract：:We analyzed the genetic architecture of prepubertal development of relative weight to height in 216 monozygotic and 159 dizygotic complete Japanese twin pairs (52% girls). Ponderal index at birth (kg/m(3)) and body mass index (BMI, kg/m(2)) from 1 to 11 years of age were used. Additive genetic factors explained the ma...

journal_title：Behavior genetics

authors： Silventoinen K,Kaprio J,Yokoyama Y

更新日期：2011-03-01 00:00:00

abstract：:Thirty-one female subjects with Turner syndrome (TS) and 31 normal females matched for age and verbal IQ were given a spatial task requiring the mental rotation of geometric figures. The results revealed a poorer performance by the TS group for most items involving rotations. The relationship between reaction time and...

journal_title：Behavior genetics

authors： Rovet J,Netley C

更新日期：1980-09-01 00:00:00

abstract：:Roman high- and low-avoidance (RHA/Verh and RLA/Verh) rats are selected and bred for extreme divergence in two-way active avoidance acquisition. In addition, compared to RLA/Verh rats, RHA/Verh rats are (behaviorally and physiologically) less anxious or reactive to stressors, show increased novelty (sensation)-seeking...

journal_title：Behavior genetics

authors： Fernández-Teruel A,Escorihuela RM,Castellano B,González B,Tobeña A

更新日期：1997-11-01 00:00:00