解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Genetic heritability (h2) of alcohol use is reported to be greater in rural dwellers, distressed marriages, low socioeconomic status, in girls who are unmarried or lacking closeness with their parents or religious upbringing, in less-educated men, and in adolescents with peers using alcohol. However, these are all ris...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-020-10005-z
更新日期:2020-09-01 00:00:00
abstract::A wealth of literature suggests that normative and heavy alcohol consumption continue to follow a historical pattern of greater prevalence among males as compared to females. Some prior research suggested that sex-specific factors might explain some of this gender gap. Generally speaking, though, more recent studies h...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-020-10004-0
更新日期:2020-09-01 00:00:00
abstract::This study documented the etiology contributions between anxiety symptoms (AS) and depressive symptoms (DS) from ages 6-12 years. Teachers assessed AS and DS in 1112 twins at 5 time points. A genetic cross-lagged model was used to estimate genetic/environmental contributions to cross-sectional, cross-age and cross-lag...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-019-09988-1
更新日期:2020-03-01 00:00:00
abstract::Feather pecking (FP) is a serious economic and welfare problem in the domestic fowl. It has recently been shown that the distribution of FP bouts within groups is heterogeneous and contains a sub-population of extreme feather peckers (EFP). The present study proposed a novel model to detect EFP hens. A mixture of two ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-019-09971-w
更新日期:2020-01-01 00:00:00
abstract::We investigated the extent to which performance on standardized achievement tests, executive function (EF), and aggression in childhood and adolescence accounted for the relationship between a polygenic score for educational attainment (EA PGS) and years of education in a community sample of African Americans. Partici...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-019-09982-7
更新日期:2020-01-01 00:00:00
abstract::Bullying comes in different forms, yet most previous genetically-sensitive studies have not distinguished between them. Given the serious consequences and the high prevalence of bullying, it is remarkable that the aetiology of bullying and its different forms has been under-researched. We present the first study to in...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-019-09968-5
更新日期:2019-09-01 00:00:00
abstract::The ε4 allele of the apolipoprotein (APOE) gene is a widely recognized genetic risk factor for developing Alzheimer's disease in older age. However, it is controversial whether there is a positive impact of the APOE ε4 allele on human cognitive performance in young adulthood, possibly representing a case of antagonist...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-019-09961-y
更新日期:2019-09-01 00:00:00
abstract::In the original version of this article, unfortunately, in the acknowledgement section "National Institutes of Health (NIH, R37 AG033590-08) to J Cacioppo" was omitted. This has been corrected by publishing this erratum. ...
journal_title:Behavior genetics
pub_type: 已发布勘误
doi:10.1007/s10519-019-09956-9
更新日期:2019-05-01 00:00:00
abstract::The role of non-shared environment (NSE) in the development of psychological traits is usually comparable with that of the genotype. However, no specific factors of NSE with significant impact on such traits have been discovered so far. We propose that the current failures in understanding the origin of NSE are at lea...
journal_title:Behavior genetics
pub_type: 杂志文章,评审
doi:10.1007/s10519-019-09950-1
更新日期:2019-05-01 00:00:00
abstract::Offspring outcomes are a function of maternal genetics operating on the intrauterine and postnatal environment, offspring genetics and environmental factors. Partitioning genetic effects into maternal and offspring components requires genotyped mother-offspring pairs or genotyped individuals with phenotypic informatio...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-018-9944-9
更新日期:2019-05-01 00:00:00
abstract::Cannabis use is linked to positive and negative outcomes. Identifying genetic targets of susceptibility to the negative effects of cannabinoid use is of growing importance. The current study sought to complete short-term selective breeding for adolescent sensitivity and resistance to the locomotor effects of a single ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-018-9894-2
更新日期:2018-05-01 00:00:00
abstract::This study used a theoretically-derived set of items of the Achenbach System of Empirically Based Assessment to develop the Achenbach Self-Control Scale (ASCS) for 7-16 year olds. Using a large dataset of over 20,000 children, who are enrolled in the Netherlands Twin Register, we demonstrated the psychometric properti...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-018-9887-1
更新日期:2018-03-01 00:00:00
abstract::For the participants in the Netherlands Twin Register (NTR) we constructed the extended pedigrees which specify all relations among nuclear and larger twin families in the register. A total of 253,015 subjects from 58,645 families were linked to each other, to the degree that we had information on the relations among ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-017-9872-0
更新日期:2018-01-01 00:00:00
abstract::We used an alternate age variable, functional biological age (fBioAge), which was based on performance on functional body measures. The aim was to examine development of fBioAge across the adult life span, and to also examine potential gender differences and genetic and environmental influences on change with age. We ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-017-9851-5
更新日期:2017-07-01 00:00:00
abstract::Five species of whale with matrilineal social systems (daughters remain with mothers) have remarkably low levels of mitochondrial DNA diversity. Non-heritable matriline-level demography could reduce genetic diversity but the required conditions are not consistent with the natural histories of the matrilineal whales. T...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-017-9840-8
更新日期:2017-05-01 00:00:00
abstract::Callous-unemotional (CU) traits comprise the core symptoms of psychopathy, yet no study has estimated the heritability of CU traits in a community sample of children using an instrument designed solely to assess CU traits. The current study uses data from 339 twin pairs aged 9-14 to examine the reliability and heritab...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-016-9831-1
更新日期:2017-03-01 00:00:00
abstract::In studies of child psychopathology, phenotypes of interest are often obtained by parental ratings. When behavioral ratings are obtained in the context of a twin study, this allows for the decomposition of the phenotypic variance, into a genetic and a non-genetic part. If a phenotype is assessed by a single rater, her...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-016-9823-1
更新日期:2017-03-01 00:00:00
abstract::Individuals involved in a social interaction exhibit different behavioral traits that, in combination, form the individual's behavioral responses. Selectively bred strains of silver foxes (Vulpes vulpes) demonstrate markedly different behaviors in their response to humans. To identify the genetic basis of these behavi...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-016-9815-1
更新日期:2017-01-01 00:00:00
abstract::The zebrafish enjoys several advantages over other model organisms. It is small, easy to maintain, prolific, and numerous genetic tools are available for it. For example, forward genetic screens have allowed investigators to identify important genes potentially involved in a variety of functions from embryogenesis to ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-016-9818-y
更新日期:2017-01-01 00:00:00
abstract::Common SNPs in nicotinic acetylcholine receptor genes (CHRN genes) have been associated with drug behaviors and personality traits, but the influence of rare genetic variants is not well characterized. The goal of this project was to identify novel rare variants in CHRN genes in the Center for Antisocial Drug Dependen...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-016-9792-4
更新日期:2016-09-01 00:00:00
abstract::Testis specific protein, Y-encoded-like 2 (TSPYL2) regulates the expression of genes encoding glutamate receptors. Glutamate pathology is implicated in neurodevelopmental conditions such as autism spectrum disorder, attention deficit hyperactivity disorder (ADHD) and schizophrenia. In line with this, a microduplicatio...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-015-9777-8
更新日期:2016-07-01 00:00:00
abstract::In epidemiological and twin populations, prior interview studies have identified an externalizing spectrum of disorders. Could this be detected utilizing objective registry data? In 20,603 twin pairs from the Swedish Twin Registry, we obtained information from national medical, criminal and pharmacy records on drug ab...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-015-9741-7
更新日期:2016-03-01 00:00:00
abstract::Complex illnesses, like depression, are thought to arise from the interplay between psychosocial stressors and genetic predispositions. Approaches that take into account both personal and neighborhood factors and that consider gene regions as well as individual SNPs may be necessary to capture these interactions acros...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-015-9734-6
更新日期:2016-01-01 00:00:00
abstract::To extend Purcell's well known ACE model in testing gene by measured environment interactions (GxM) in behavior genetic designs, Rathouz et al. considered a broader class of models for quantifying and testing such interactions. Only a sub-group of these extended models have been investigated for their statistical oper...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-015-9710-1
更新日期:2015-07-01 00:00:00
abstract::Manipulation of endogenous levels of the GABAergic neurosteroid allopregnanolone alters sensitivity to some effects of ethanol. Chronic ethanol withdrawal decreases activity and expression of 5α-reductase-1, an important enzyme in allopregnanolone biosynthesis encoded by the 5α-reductase-1 gene (Srd5a1). The present s...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9691-5
更新日期:2015-05-01 00:00:00
abstract::A powerful longitudinal data source, the National Longitudinal Survey of Youth Children data, allows measurement of behavior problems (BP) within a developmental perspective linking them to menarcheal timing (MT). In a preliminary analysis, we evaluate the bivariate relationships between BP measured at different devel...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9676-4
更新日期:2015-01-01 00:00:00
abstract::Here we provide a detailed description of the genome-wide information available on the National Longitudinal Study of Adolescent to Adult Health (Add Health) sibling pair subsample (Harris et al. in Twin Res Hum Genet 16:391-398, 2013). A total of 2,020 samples were genotyped (including duplicates) arising from 1946 A...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9692-4
更新日期:2015-01-01 00:00:00
abstract::Genome wide complex trait analysis (GCTA) is extended to include environmental effects of the maternal genotype on offspring phenotype ("maternal effects", M-GCTA). The model includes parameters for the direct effects of the offspring genotype, maternal effects and the covariance between direct and maternal effects. A...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9666-6
更新日期:2014-09-01 00:00:00
abstract::This study uses longitudinal population-based samples of young siblings to examine the effects of two hypothesized moderators of early externalizing behaviors: parental emotional support and family socioeconomic status. The first sample, a twin sample from the Early Childhood Longitudinal Study-Birth Cohort (ECLS-B), ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9664-8
更新日期:2014-09-01 00:00:00
abstract::The non-synonymous SNP rs2228145 in the IL6R gene on chromosome 1q21.3 is associated with a wide range of common diseases, including asthma, rheumatoid arthritis, type 1 diabetes and coronary heart disease. We examined the contribution of this functional IL6R gene polymorphism rs2228145 versus other genome-wide SNPs t...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9656-8
更新日期:2014-07-01 00:00:00
abstract::Previous studies have shown associations between single nucleotide polymorphisms (SNPs) in gamma aminobutyric acid receptor alpha 2 (GABRA2) and adolescent conduct disorder (CD) and alcohol dependence in adulthood, but not adolescent alcohol dependence. The present study was intended as a replication and extension of ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9653-y
更新日期:2014-07-01 00:00:00
abstract::Almost 40 years ago, evidence from large studies of adult twins and their relatives suggested that between 30 and 60% of the variance in social and political attitudes could be explained by genetic influences. However, these findings have not been widely accepted or incorporated into the dominant paradigms that explai...
journal_title:Behavior genetics
pub_type: 杂志文章,meta分析
doi:10.1007/s10519-014-9648-8
更新日期:2014-05-01 00:00:00
abstract::Human facial attractiveness and facial sexual dimorphism (masculinity-femininity) are important facets of mate choice and are hypothesized to honestly advertise genetic quality. However, it is unclear whether genes influencing facial attractiveness and masculinity-femininity have similar, opposing, or independent effe...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-013-9627-5
更新日期:2014-05-01 00:00:00
abstract::Adolescent depression is common and has become a major public health concern in China, yet little research has examined the etiology of depression in Chinese adolescents. In the present study, genetic and environmental influences on Chinese adolescent depressive symptoms were investigated in 1,181 twin pairs residing ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-013-9632-8
更新日期:2014-01-01 00:00:00
abstract::Gender-moderated gene-environment interactions are rarely explored, raising concerns about inaccurate specification of etiological models and inferential errors. The current study examined the influence of gender, negative and positive daily life events, and GABRA2 genotype (SNP rs279871) on alcohol dependence, testin...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-013-9607-9
更新日期:2013-09-01 00:00:00
abstract::Previous animal studies have revealed significant involvement of genetics in nicotine intake; however, the extent of the genetic contribution to this behavior has not been well addressed. We report the first study of nine generations of selection for high and low voluntary nicotine intake in outbred Sprague-Dawley rat...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-013-9605-y
更新日期:2013-09-01 00:00:00
abstract::The heritability of human personality is well-established. Recent research indicates that nonadditive genetic effects, such as dominance and epistasis, play a large role in personality variation. One possible explanation for the latter finding is that there has been recent selection on human personality. To test this ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-012-9537-y
更新日期:2012-07-01 00:00:00
abstract::Reading difficulties are both heritable and stable; however, little is known about the etiology of this stability. Results from a preliminary analysis of data from 56 twin pairs who participated in the Colorado Longitudinal Twin Study of Reading Disability (Astrom et al., Twin Res Hum Genet 10:434-439, 2007) suggested...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-011-9445-6
更新日期:2011-09-01 00:00:00
abstract::In the present study we evaluated long term memory in twenty individuals with molecularly confirmed diagnosis of Noonan syndrome and LEOPARD syndrome, two disorders caused by mutations in genes coding transducers participating in the RAS-MAPK signaling cascade. The profile of explicit long term memory abilities was in...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-011-9446-5
更新日期:2011-05-01 00:00:00
abstract::We report on a cross-syndrome comparison of hand, foot, eye and ear laterality in three groups of individuals with different genetic disorders (trisomy 21, del7q11.23, and del22q11.2) to test the relationship between atypical laterality and intellectual disability. These groups were compared to a group of typically de...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-011-9465-2
更新日期:2011-05-01 00:00:00