Abstract:
:We analyzed the genetic architecture of prepubertal development of relative weight to height in 216 monozygotic and 159 dizygotic complete Japanese twin pairs (52% girls). Ponderal index at birth (kg/m(3)) and body mass index (BMI, kg/m(2)) from 1 to 11 years of age were used. Additive genetic factors explained the major proportion (52-74%) of the variation of BMI from 1 to 11 years of age. Environmental factors common to both co-twins also showed some effect (7-28%), but at most ages this was not statistically significant. Strong genetic tracking was found for BMI from 1 to 11 years of age, but there was also evidence for a persistent effect of common environmental factors. Our results suggest that the genetic architecture of BMI development in the Japanese population is generally similar to that found in previous twin studies in Caucasian populations.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
Silventoinen K,Kaprio J,Yokoyama Ydoi
10.1007/s10519-010-9380-ysubject
Has Abstractpub_date
2011-03-01 00:00:00pages
234-41issue
2eissn
0001-8244issn
1573-3297journal_volume
41pub_type
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