Abstract:
:Genomewide scan, as shown by recently published linkage studies on the behavior of mice or in psychiatry, provides evidence for replicated quantitative trait loci (QTL). Several studies of Alzheimer's disease have demonstrated the promise of moving from clinical diagnoses to biological signs for psychiatric investigations. Empirical studies also demonstrate that genetic background, differences in environment, epistatic effects, and definition of the phenotype (including psychiatric diagnosis) all actively contribute to limit the duplication of QTL.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
Roubertoux PL,Le Roy-Duflos Idoi
10.1023/a:1010222328509subject
Has Abstractpub_date
2001-01-01 00:00:00pages
141-8issue
1eissn
0001-8244issn
1573-3297journal_volume
31pub_type
杂志文章abstract::The amygdala integrates and coordinates emotional and autonomic responses. The genetics that underlie variation in amygdala structure may be coupled to variation in levels of aggression, fear, anxiety, and affiliated behaviors. We systematically quantified the volume and cell populations of the basolateral amygdala co...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-006-9122-3
更新日期:2007-01-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01067662
更新日期:1991-01-01 00:00:00
abstract::Selection for high and low locomotor activity has been applied in two base populations of Drosophila melanogaster of distinct geographical origin. From each base population a high and a low line were selected, in which anesthesia was performed with ether. In addition, from one of the base populations a high line and a...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01067350
更新日期:1979-11-01 00:00:00
abstract::The heritability of human personality is well-established. Recent research indicates that nonadditive genetic effects, such as dominance and epistasis, play a large role in personality variation. One possible explanation for the latter finding is that there has been recent selection on human personality. To test this ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-012-9537-y
更新日期:2012-07-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01066164
更新日期:1989-05-01 00:00:00
abstract::It is well established that many continuously distributed traits have a heritable component. However, it is often difficult to communicate to the general public the meaning of quantitative estimates of heritability. To address this problem, the present paper introduces a heuristic for communicating heritability to non...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1025670316169
更新日期:1997-09-01 00:00:00
abstract::Mating behavior, including courtship and copulation, is a main component of male fitness, especially in species with no parental care. Variation in this behavior can thus be a target for mate choice and sexual selection, and can lead to evolution. The fruit fly, Drosophila melanogaster, has well-documented complex mal...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-008-9204-5
更新日期:2008-07-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-010-9379-4
更新日期:2011-03-01 00:00:00
abstract::The concept of generalist genes operating across diverse domains of cognitive abilities is now widely accepted. Much less is known about the etiology of the high extreme of performance. Is there more specialization at the high extreme? Using a representative sample of 4,000 12-year-old twin pairs from the UK Twins Ear...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-009-9271-2
更新日期:2009-07-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1020880211144
更新日期:2002-11-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01070002
更新日期:1981-09-01 00:00:00
abstract::We review the literature on the familial resemblance of body mass index (BMI) and other adiposity measures and find strikingly convergent results for a variety of relationships. Results from twin studies suggest that genetic factors explain 50 to 90% of the variance in BMI. Family studies generally report estimates of...
journal_title:Behavior genetics
pub_type: 杂志文章,评审
doi:10.1023/a:1025635913927
更新日期:1997-07-01 00:00:00
abstract::Percentages of left-handed relatives were compared between subgroups of left-handers and of right-handers to test the prediction that the subgroups are ordered for probability of carrying the rs +/gene (hypothesized by the right-shift theory of handedness). Data included families of undergraduates and Open University ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01067928
更新日期:1994-01-01 00:00:00
abstract::Heterozygous staggerer mice (Rora(+)/Rora(sg)) and control mice (Rora(+)/Rora(+)) of the same C57BL/6J strain background were tested in a spontaneous alternation task at 3 to 24 months old. The results demonstrated a decrement in long-term working memory as early as 6 months in Rora(+)/Rora(+) mice and at 3 months in ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/B:BEGE.0000017875.78571.a6
更新日期:2004-05-01 00:00:00
abstract::Parameters of quantitative genetic models have traditionally been estimated by either algebraic manipulation of familial correlations (or familial mean squares), biometric model fitting, or multiple-group covariance structure analysis. With few exceptions, researchers who have used these methods for the analysis of tw...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01066662
更新日期:1992-05-01 00:00:00
abstract::In the present study we evaluated long term memory in twenty individuals with molecularly confirmed diagnosis of Noonan syndrome and LEOPARD syndrome, two disorders caused by mutations in genes coding transducers participating in the RAS-MAPK signaling cascade. The profile of explicit long term memory abilities was in...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-011-9446-5
更新日期:2011-05-01 00:00:00
abstract::In the original version of this article, unfortunately, in the acknowledgement section "National Institutes of Health (NIH, R37 AG033590-08) to J Cacioppo" was omitted. This has been corrected by publishing this erratum. ...
journal_title:Behavior genetics
pub_type: 已发布勘误
doi:10.1007/s10519-019-09956-9
更新日期:2019-05-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-004-1747-5
更新日期:2005-07-01 00:00:00
abstract::Social aggregations of free-ranging cattle were studied in the Sonoran Desert of Mexico. Cows reared with animals of their own breed in isolation from other breeds maintained segregated social groups. Cows raised together in a mixed herd containing other breeds allied themselves with herd-mates regardless of breed. Ca...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01065562
更新日期:1990-05-01 00:00:00
abstract::A model of handedness incorporating both genetic and cultural processes is proposed, based on an evolutionary analysis, and maximum-likelihood estimates of its parameters are generated. This model has the characteristics that (i) no genetic variation underlies variation in handedness, and (ii) variation in handedness ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF02253372
更新日期:1995-09-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01066617
更新日期:1992-07-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01065888
更新日期:1989-01-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01068210
更新日期:1979-07-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01065601
更新日期:1980-07-01 00:00:00
abstract::Gender-moderated gene-environment interactions are rarely explored, raising concerns about inaccurate specification of etiological models and inferential errors. The current study examined the influence of gender, negative and positive daily life events, and GABRA2 genotype (SNP rs279871) on alcohol dependence, testin...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-013-9607-9
更新日期:2013-09-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01070816
更新日期:1981-07-01 00:00:00
abstract::In studies of child psychopathology, phenotypes of interest are often obtained by parental ratings. When behavioral ratings are obtained in the context of a twin study, this allows for the decomposition of the phenotypic variance, into a genetic and a non-genetic part. If a phenotype is assessed by a single rater, her...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-016-9823-1
更新日期:2017-03-01 00:00:00
abstract::To extend Purcell's well known ACE model in testing gene by measured environment interactions (GxM) in behavior genetic designs, Rathouz et al. considered a broader class of models for quantifying and testing such interactions. Only a sub-group of these extended models have been investigated for their statistical oper...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-015-9710-1
更新日期:2015-07-01 00:00:00
abstract::The paradise fish, a small insectivore, coinhabits marshes of Southeast Asia with several predator fish species. Its ability to recognize and avoid harmful fish may depend upon both genetic factors and experience. Here we demonstrate genetic variability between the 20-day-old larvae of two inbred strains of paradise f...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1025601828464
更新日期:1997-05-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1025607107566
更新日期:1997-01-01 00:00:00