Abstract:
:Selection for high and low locomotor activity has been applied in two base populations of Drosophila melanogaster of distinct geographical origin. From each base population a high and a low line were selected, in which anesthesia was performed with ether. In addition, from one of the base populations a high line and a low line were selected under CO2 narcosis. Locomotor activity was measured in an apparatus consisting of rows of 20 tubes in a line. Heritabilities in the base populations determined in progeny tests were approximately 10%. Divergent directional selection was successful with realized heritabilities of similar value.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
van Dijken FR,Scharloo Wdoi
10.1007/BF01067350subject
Has Abstractpub_date
1979-11-01 00:00:00pages
543-53issue
6eissn
0001-8244issn
1573-3297journal_volume
9pub_type
杂志文章abstract::Here we provide a detailed description of the genome-wide information available on the National Longitudinal Study of Adolescent to Adult Health (Add Health) sibling pair subsample (Harris et al. in Twin Res Hum Genet 16:391-398, 2013). A total of 2,020 samples were genotyped (including duplicates) arising from 1946 A...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9692-4
更新日期:2015-01-01 00:00:00
abstract::Parameter estimates from analyses of univariate twin data usually do not reflect the uncertainty due to the model selection phase of the data analysis. To address the effect of model selection uncertainty on parameter estimates, we introduce frequentist model-averaged estimators for univariate twin data analysis that ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-006-9065-8
更新日期:2006-09-01 00:00:00
abstract::Callous-unemotional (CU) traits comprise the core symptoms of psychopathy, yet no study has estimated the heritability of CU traits in a community sample of children using an instrument designed solely to assess CU traits. The current study uses data from 339 twin pairs aged 9-14 to examine the reliability and heritab...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-016-9831-1
更新日期:2017-03-01 00:00:00
abstract::Lurcher mutant mice were impaired in spatial orientation and motor coordination in comparison to normal mice. Both groups improved across days in both invisible and visible water maze platform conditions. Contrary to normal mice, lurcher mutants did not improve over days in terms of the time taken to reach a side-bar ...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01071563
更新日期:1994-11-01 00:00:00
abstract::It has been hypothesized that numerous genes contribute to individual variation in human cognition. An extensive search of the scientific literature was undertaken to identify candidate genes which might contribute to this complex trait. A list of over 150 candidate genes that may influence some aspect of cognition wa...
journal_title:Behavior genetics
pub_type: 杂志文章,评审
doi:10.1023/a:1013337209957
更新日期:2001-11-01 00:00:00
abstract::Two ongoing selective breeding projects have produced mice that display divergent analgesic responses to morphine. These two projects have selected for similar phenotypes: high and low levorphanol analgesia (HAR/LAR lines; Portland, OR) and high and low swim stress-induced analgesia (HA/LA lines; Jastrzebiec, Poland)....
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF02197290
更新日期:1995-07-01 00:00:00
abstract::To extend Purcell's well known ACE model in testing gene by measured environment interactions (GxM) in behavior genetic designs, Rathouz et al. considered a broader class of models for quantifying and testing such interactions. Only a sub-group of these extended models have been investigated for their statistical oper...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-015-9710-1
更新日期:2015-07-01 00:00:00
abstract::The Inositol 1,4,5-triphosphate (IP3) route is one of the two main transduction cascades that mediate olfactory reception in Drosophila melanogaster. The activity of IP3 kinase1 reduces the levels of this substrate by phosphorylation into inositol 1,3,4,5-tetrakiphosphate (IP4). We show here that the gene is expressed...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-005-9031-x
更新日期:2006-03-01 00:00:00
abstract::Among three sibling species of the D. melanogaster subgroup, two are generalists (D. simulans and D. mauritiana), while the third, D. sechellia, specializes on a single toxic resource, the fruit of Morinda citrifolia. D. sechellia, resistant to the toxics, prefers to oviposit on morinda; D. simulans, which is very sen...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01076179
更新日期:1994-09-01 00:00:00
abstract::Sex differences in genetic and environmental influences on criminal behavior against property were studied in a birth cohort of 6129 male and 7065 female Danish adoptees and their biological and adoptive parents. Both genetic and environmental factors were found to contribute to variation in liability to property crim...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01066164
更新日期:1989-05-01 00:00:00
abstract::Complex illnesses, like depression, are thought to arise from the interplay between psychosocial stressors and genetic predispositions. Approaches that take into account both personal and neighborhood factors and that consider gene regions as well as individual SNPs may be necessary to capture these interactions acros...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-015-9734-6
更新日期:2016-01-01 00:00:00
abstract::Previous studies suggest that brain opioid activity decreases aggression in animal models. The main objective of the current study was to examine the possible genetic relationship between intermale aggression and brain levels of enkephalins, endorphins, and dynorphins in 11 inbred strains of mice. Pursuit, rattling, a...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1025774716976
更新日期:2003-09-01 00:00:00
abstract::Differences between population-typical norms of individual variability were studied in five genetic lines of Japanese quail (Coturnix coturnix japonica); two (BL and RL) were bidirectionally selected for early approach preference between blue and red stimuli, two (Hi and Lo) for high and low imprintabilities to the sa...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01074309
更新日期:1992-09-01 00:00:00
abstract::Genome wide complex trait analysis (GCTA) is extended to include environmental effects of the maternal genotype on offspring phenotype ("maternal effects", M-GCTA). The model includes parameters for the direct effects of the offspring genotype, maternal effects and the covariance between direct and maternal effects. A...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-014-9666-6
更新日期:2014-09-01 00:00:00
abstract::Using high resolution magnetic resonance imaging data, we examined the interrelationships between eight cerebral lobar volumetric measures via both exploratory and confirmatory factor analyses in a large sample (N = 484) of pediatric twins and singletons. These analyses suggest the presence of strong genetic correlati...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-010-9332-6
更新日期:2010-03-01 00:00:00
abstract::It is well established that many continuously distributed traits have a heritable component. However, it is often difficult to communicate to the general public the meaning of quantitative estimates of heritability. To address this problem, the present paper introduces a heuristic for communicating heritability to non...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1025670316169
更新日期:1997-09-01 00:00:00
abstract::Previous animal studies have revealed significant involvement of genetics in nicotine intake; however, the extent of the genetic contribution to this behavior has not been well addressed. We report the first study of nine generations of selection for high and low voluntary nicotine intake in outbred Sprague-Dawley rat...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-013-9605-y
更新日期:2013-09-01 00:00:00
abstract::Extreme sampling of sibling pairs has been shown to be efficient in terms of statistical power and sample sizes (in number of sibling pairs needed to genotype) to detect a quantitative trait locus (QTL) when the residual distribution is normal. In the present study, the efficiency of extreme sampling strategies to det...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1023/a:1014403827957
更新日期:2002-01-01 00:00:00
abstract::We analyzed the genetic architecture of prepubertal development of relative weight to height in 216 monozygotic and 159 dizygotic complete Japanese twin pairs (52% girls). Ponderal index at birth (kg/m(3)) and body mass index (BMI, kg/m(2)) from 1 to 11 years of age were used. Additive genetic factors explained the ma...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-010-9380-y
更新日期:2011-03-01 00:00:00
abstract::In this study we analyzed the etiology of the relationship between personality traits and retrospectively recalled family environment. The data of 226 identical and 168 fraternal twin pairs reared together from the Jena twin study of social attitudes were available. Personality traits were measured using the self- and...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-008-9238-8
更新日期:2009-01-01 00:00:00
abstract::In studies of child psychopathology, phenotypes of interest are often obtained by parental ratings. When behavioral ratings are obtained in the context of a twin study, this allows for the decomposition of the phenotypic variance, into a genetic and a non-genetic part. If a phenotype is assessed by a single rater, her...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-016-9823-1
更新日期:2017-03-01 00:00:00
abstract::Almost 40 years ago, evidence from large studies of adult twins and their relatives suggested that between 30 and 60% of the variance in social and political attitudes could be explained by genetic influences. However, these findings have not been widely accepted or incorporated into the dominant paradigms that explai...
journal_title:Behavior genetics
pub_type: 杂志文章,meta分析
doi:10.1007/s10519-014-9648-8
更新日期:2014-05-01 00:00:00
abstract::In the course of the East Flanders Prospective Twin Survey (EFPTS), handedness was assessed as part of a genealogical study (Meulemans et al., 1995) in 1616 twins (808 twin pairs) aged 6 to 28. Our findings are that, in this large population-based study with known placentation and zygosity, the often observed higher f...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF02359484
更新日期:1996-07-01 00:00:00
abstract::Roman high- and low-avoidance (RHA/Verh and RLA/Verh) rats are selected and bred for extreme divergence in two-way active avoidance acquisition. In addition, compared to RLA/Verh rats, RHA/Verh rats are (behaviorally and physiologically) less anxious or reactive to stressors, show increased novelty (sensation)-seeking...
journal_title:Behavior genetics
pub_type: 杂志文章,评审
doi:10.1023/a:1021400830503
更新日期:1997-11-01 00:00:00
abstract::Testis specific protein, Y-encoded-like 2 (TSPYL2) regulates the expression of genes encoding glutamate receptors. Glutamate pathology is implicated in neurodevelopmental conditions such as autism spectrum disorder, attention deficit hyperactivity disorder (ADHD) and schizophrenia. In line with this, a microduplicatio...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-015-9777-8
更新日期:2016-07-01 00:00:00
abstract::A large sample of adult twins (1117 pairs), who were concordant for having had children were asked to report on their child-rearing practices. A 14-item version of the Parental Bonding Instrument (PBI) was used to assess rearing practices of parent twins. The two factors of Care and Overprotection, commonly found in o...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01067533
更新日期:1994-07-01 00:00:00
abstract::Taste perception allows most animals to find edible food, potential mates, and avoid ingesting toxic molecules. Intriguingly, a small group of Drosophila taste neurones (expressing Gr66a-Gal4) involved in the perception of bitter substances is also used to detect 7-tricosene (7-T), a male cuticular pheromone. Male fli...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-009-9286-8
更新日期:2009-09-01 00:00:00
abstract::Most research on child behavior incorporates information from different individuals. While agreement between informants is generally only modest, there is little understanding of the processes underlying disagreement. In twin studies, differential agreement among raters for MZ and DZ twins is of particular concern. Th...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF02197280
更新日期:1995-07-01 00:00:00
abstract::Male Drosophila melanogaster from lines artificially selected to have divergent life histories were tested to determine if they differed in their effects on female reproductive behavior. During the first 5 days after mating, males from short-generation populations caused females to lay eggs at a faster rate than did m...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF02361157
更新日期:1996-01-01 00:00:00
abstract::Twin studies are useful for assessing the relative importance of genetic or heritable component from the environmental component. In this paper we develop a methodology to study the heritability of age-at-onset or lifespan traits, with application to analysis of twin survival data. Due to limited period of observation...
journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-007-9150-7
更新日期:2007-07-01 00:00:00