Abstract:
:Lurcher mutant mice were impaired in spatial orientation and motor coordination in comparison to normal mice. Both groups improved across days in both invisible and visible water maze platform conditions. Contrary to normal mice, lurcher mutants did not improve over days in terms of the time taken to reach a side-bar in a motor coordination test, an indication of defective motor learning. However, lurchers were able to stay on the bar longer across days. These results indicate that motor learning deficits in this cerebellar-damaged animal are not absolute but dependent on the type of measurement attempted. There was no correlation between motor coordination and spatial orientation for normal mice. A similar absence of correlation was noted for lurcher mutants, except for falling latencies in the coat-hanger test during the middle of training.
journal_name
Behav Genetjournal_title
Behavior geneticsauthors
Lalonde R,Thifault Sdoi
10.1007/BF01071563subject
Has Abstractpub_date
1994-11-01 00:00:00pages
497-501issue
6eissn
0001-8244issn
1573-3297journal_volume
24pub_type
杂志文章abstract::Genes involved in melatonin synthesis, such as Aa-nat, may be important for our understanding of diurnal preference and circadian rhythm disturbances in humans. In Japan, Hohjoh et al. reported increased allelic frequencies of the 619A allele of the G619A Aa-nat gene polymorphism in a sample of Delayed Sleep Phase Syn...
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journal_title:Behavior genetics
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pub_type: 杂志文章,评审
doi:10.1007/BF02359383
更新日期:1996-05-01 00:00:00
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pub_type: 杂志文章
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更新日期:2007-03-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
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更新日期:1997-05-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s10519-008-9197-0
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更新日期:2009-01-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/BF01066177
更新日期:1975-07-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
doi:10.1007/s10519-009-9308-6
更新日期:2010-01-01 00:00:00
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journal_title:Behavior genetics
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Behavior genetics
pub_type: 杂志文章
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更新日期:1990-01-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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